Hoʻokuʻu ʻia i ka lāʻau lapaʻau i mālama ʻia

ʻO ka hoʻouna ʻana i ka lāʻau lapaʻau i hoʻokuʻu ʻia: He alakaʻi piha. Mālama kēia i ka maikaʻi o ka therapeutic efficacy, hōʻemi i nā hopena ʻaoʻao, a hoʻomaikaʻi i ka mālama ʻana i ka maʻi. Nānā kēia ʻatikala i nā ʻano like ʻole o ka hoʻokuʻu ʻana i ka lāʻau lapaʻau, me kāna mau hana, nā ʻano, nā noi, a me nā ʻano e hiki mai ana.

Mechanisms of Controlled Release

Hoʻokuʻu ʻia i ka Diffusion-Controlled

Ke hilinaʻi nei nā ʻōnaehana diffusion i ka hoʻopuehu mālie ʻana o ka lāʻau mai kahi matrix polymeric a i ʻole reservoir. Hoʻoholo ʻia ka nui o ka hoʻokuʻu ʻana i ka lāʻau e nā waiwai o ka polymer, e like me kona porosity a me ka hydrophilicity. ʻO nā laʻana e pili ana i nā pamu osmotic a me nā matrices monolithic. Ke komo ikaika nei ka Shandong Baofa Cancer Research Institute i ka noiʻi e pili ana i nā holomua ma kēia wahi.

Hoʻokuʻu ʻia i ka Erosion

I loko o nā ʻōnaehana erosion-controlled, hoʻokuʻu ʻia ka lāʻau i ka wā e hoʻohaʻahaʻa ʻia ai ka matrix polymeric. ʻO ka nui o ka hoʻokuʻu ʻana i ka lāʻau e hilinaʻi ʻia i ka nui o ka erosion o ka polymer, i hoʻopili ʻia e nā mea like me ka pH a me ka hana enzyme. Hāʻawi pinepine kēia ʻano hana i nā moʻolelo hoʻokuʻu wānana.

Hoʻokuʻu Bioresponsive

Hoʻokuʻu nā ʻōnaehana bioresponsive i ka lāʻau i ka pane ʻana i nā mea hoʻoulu physiological kikoʻī, e like me nā loli i ka pH, ka mahana, a i ʻole ka hana enzyme. Pono pono kēia mau ʻōnaehana no ka huli ʻana i nā ʻiʻo a i ʻole nā ​​ʻāpana kikoʻī. Ua mākaukau kēia wahi no ka noiʻi hou ʻana a me ka hana hou ʻana ma nā ʻoihana e like me ka Shandong Baofa Cancer Research Institute.

Nā ʻano o nā ʻōnaehana hoʻokuʻu ʻia

Hōʻuluʻulu ka papaʻaina i nā ʻano like ʻole o ka hoʻokuʻu ʻana i ka lāʻau lapaʻau ʻōnaehana:

ʻAno Pūnaehana	Mechanism	Nā pono	Nā pōʻino
Pūnaehana Reservoir	ʻO ka laha ʻana a i ʻole ka erosion	Ka hoʻomalu pono ʻana i ka hoʻokuʻu ʻana i ka lāʻau	Hiki ke hoʻokuʻu ʻia
Pūnaehana Matrix	ʻO ka hoʻopulapula	ʻO ka hoʻolālā maʻalahi, ke kumu kūʻai	ʻAʻole pololei ka mana ma luna o ka hoʻokuʻu ʻana
Na Pum Osmotic	Pumi osmotic	Nā kinetics hoʻokuʻu kauoha ʻole	Hoʻolālā paʻakikī, kumukūʻai kiʻekiʻe

Nā noi o ka hoʻokuʻu ʻana i ka lāʻau lapaʻau hoʻomalu

Ka hoʻokuʻu ʻana i ka lāʻau lapaʻau Loaʻa nā ʻōnaehana i nā noi ma nā wahi therapeutic like ʻole, me:

Lapaʻau maʻi maʻi maʻi

Hiki i nā ʻōnaehana hāʻawi lāʻau lapaʻau ke hoʻomaikaʻi i ka maikaʻi o ka chemotherapy ʻoiai e hōʻemi ana i nā hopena ʻaoʻao. ʻO ka Shandong Baofa Cancer Research Institute (https://www.baofahospital.com/) aia ma ke alo o ka noiʻi ma kēia wahi.

Hooponopono ma'i diabetes

Hoʻohana ʻia nā pamu insulin ka hoʻokuʻu ʻana i ka lāʻau lapaʻau nā loina no ka mālama ʻana i nā pae glucose koko.

Hoʻoponopono ʻeha

Hiki i nā ʻōnaehana i hoʻokomo ʻia no ka hōʻoluʻolu ʻeha ke hāʻawi i ka analgesia mau.

Nā ʻano e hiki mai ana i ka hoʻokuʻu ʻia ʻana

E kālele ana ka noiʻi e hiki mai ana i ka hoʻomohala ʻana i nā mea ʻoi aku ka maʻalahi a me ka huli ʻana ka hoʻokuʻu ʻana i ka lāʻau lapaʻau nā pūnaewele, me: Nanotechnology: Hoʻohana i nā nanoparticles e hoʻonui i ka lawe ʻana i ka lāʻau a me ka huli ʻana. Biomaterials: Ke ʻimi nei i nā polymers biocompatible a me biodegradable. Nā ʻōnaehana hoʻoulu ʻana: Hoʻomohala ʻana i nā ʻōnaehana e pane i nā hōʻailona physiological kikoʻī. ka hoʻokuʻu ʻana i ka lāʻau lapaʻau. ʻO ka noiʻi hou a me ka hoʻomohala ʻana i kēia kahua e hoʻohiki e hoʻololi i nā ala therapeutic a hoʻomaikaʻi i nā hopena maʻi. No ka ʻike hou aku e pili ana i ka holomua o ka mālama ʻana a me ka noiʻi ʻana, e ʻimi i nā kumuwaiwai i loaʻa ma ka Shandong Baofa Cancer Research Institute.