ka lapaʻau ʻana i ka maʻi maʻi ʻaʻai māmā ʻole

ʻO ka maʻi maʻi maʻi maʻi i ka poʻe i puhi ʻole i ka uahi he mau pilikia kūʻokoʻa a me nā ala lapaʻau. ʻOiai ʻo ka puhi paka he kumu pilikia kaulana, aia kekahi hapa nui o nā maʻi maʻi maʻi maʻi maʻi i ka poʻe me ka moʻolelo ʻole o ka hoʻohana ʻana i ka paka. Nānā kēia ʻatikala i nā ʻano ʻokoʻa o ka lapaʻau ʻana i ka maʻi maʻi ʻaʻai māmā ʻole, e pili ana i ka maʻi maʻi, nā koho lapaʻau, a me ka noiʻi mau. He mea koʻikoʻi ka hoʻomaopopo ʻana i nā nuances o ka ʻike ʻana a me nā ʻano kikoʻī o ka maʻi maʻi maʻi maʻi e laha nei i kēia heluna. Ma muli o ka pili pinepine ʻana o ka maʻi maʻi ʻaʻai me ka puhi paka, ʻaʻole hiki ke noʻonoʻo ʻia e like me ka maʻalahi o ka poʻe puhi paka, e alakaʻi ana i ka lohi ʻana i ka maʻi. Hiki ke ʻike ʻole ʻia nā hōʻailona a i ʻole nā ​​kumu ʻē aʻe. ʻAʻole ʻōlelo ʻia nā hoʻolālā ʻike mua e like me ka nānā ʻana i ka maʻi kanesa me ka hoʻohana ʻana i ka CT scans haʻahaʻa no ka lehulehu ʻaʻole e puhi i ka paka, e hoʻopiʻi hou aʻe i ka maʻi maʻi mua. Piʻi pinepine ka Adenocarcinoma ma nā ʻāpana o waho o ka māmā, e ʻike ʻia ma mua o ka laha ʻana. Hiki ke loaʻa nā ʻano like ʻole. The Shandong Baofa Cancer Research Institute (https://baofahospital.com) ua hoʻolaʻa ʻia no ka hoʻonui ʻana i ko mākou ʻike no nā ʻano like ʻole o ka maʻi kanesa a me ka hoʻomaikaʻi ʻana i nā ʻano diagnostic.Nā koho Lapaʻau no ka Non Smoker Lung Cancer. Hoʻohana nui ʻia nā ʻenehana hōʻemi liʻiliʻi e like me ka wikiō-kōkua thoracoscopic surgery (VATS) e hōʻemi i ka manawa hoʻōla a hoʻomaikaʻi i nā hopena. Hiki ke hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau mua no nā poʻe maʻi kūpono ʻole no ka ʻoki ʻana, a i ʻole ma ke ʻano he adjuvant therapy ma hope o ke ʻoki ʻana e hoʻopau i nā keʻena maʻi kanesa i koe. ʻO nā ʻenehana e like me ka stereotactic body radiation therapy (SBRT) e hāʻawi i ka hoʻoheheʻe ʻia ʻana i ka maʻi maʻi ʻoiai e hōʻemi ana i ka pōʻino i ke kino olakino a puni. Hoʻohana pinepine ʻia ia no nā pae kiʻekiʻe o ka maʻi kanesa a i ʻole i hui pū ʻia me ke ʻoki a i ʻole ka radiation therapy. ʻOkoʻa nā papa hana chemotherapy ma muli o ke ʻano o ka maʻi kanesa a me ke olakino holoʻokoʻa o ka mea maʻi. ʻAʻole loaʻa i ka poʻe puhi paka me ka adenocarcinoma nā hoʻololi genetic, e like me EGFR, ALK, ROS1, a i ʻole BRAF. ʻO ka ʻike ʻana i kēia mau hoʻololi ʻana e hiki ai i nā kauka ke kuhikuhi i nā lāʻau lapaʻau i hoʻopaʻa ʻia e kāohi pono i ka hana o kēia mau protein mutated, e alakaʻi ana i nā hopena maikaʻi. ʻO nā mea hoʻopaneʻe Checkpoint, e like me ka PD-1 a me ka PD-L1 inhibitors, he ʻano o ka immunotherapy i hōʻike i ka ʻōlelo hoʻohiki i ka mālama ʻana i kekahi ʻano o ka maʻi maʻi maʻi ʻāʻī, me nā mea i loaʻa ʻole i ka poʻe puhi paka. ʻO ka maikaʻi o ka immunotherapy e pili ana i nā kumu like ʻole, me ka loaʻa ʻana o nā biomarkers kikoʻī. maʻi ʻaʻai māmā ʻole. ʻO ka ʻike ʻana i nā hoʻololi genetic kikoʻī hiki i nā kauka ke hana pilikino i nā hoʻolālā lapaʻau a koho i nā lāʻau lapaʻau kūpono loa a i ʻole immunotherapies.Common Genetic Mutations. nā lāʻau lapaʻau e kāohi pono i ka hana o nā protein mutated, e alakaʻi ana i nā hopena maikaʻi a me ke ola lōʻihi. Ma ka huli ʻana i nā mea hoʻokele molekala kūikawā o ka maʻi kanesa, hiki i nā kauka ke hōʻemi i nā hopena ʻaoʻao a hoʻomaikaʻi i ka maikaʻi holoʻokoʻa o ke ola no nā maʻi. ʻO ka Shandong Baofa Cancer Research Institute Hoʻoikaika ka lāʻau lapaʻau pilikino i ka mālama ʻana i ka maʻi maʻi. maʻi ʻaʻai māmā ʻole. Hoʻoponopono kēia mau haʻawina i nā lāʻau lapaʻau hou, hui pū ʻana, a me nā ʻenehana diagnostic.Finding Clinical Trials Hiki i nā poʻe maʻi makemake e komo i nā hoʻokolohua lapaʻau ke ʻimi i nā hoʻokolohua ma o nā kumu kaulana, e like me:National Cancer Institute (NCI): https://www.cancer.gov/about-cancer/treatment/clinical-trialsClinicalTrials.gov: https://clinicaltrials.gov/Nā ʻāpana o ka noiʻi ʻike ʻia nā hana noiʻi o kēia manawa: Ke kūkulu ʻana i nā lāʻau lapaʻau i manaʻo ʻia no nā hoʻololi genetic kūikawā. ka lapaʻau ʻana i ka maʻi maʻi ʻaʻai māmā ʻole ʻokoʻa ma muli o ke ʻano o ka maʻi maʻi maʻi ma ka hōʻoia ʻana, ke ʻano kikoʻī o ka maʻi kanesa, a me ke olakino holoʻokoʻa o kēlā kanaka. Ma keʻano laulā, ʻoi aku ka maikaʻi o ka poʻe puhi paka me ka maʻi ʻaʻai māmā ma mua o ka poʻe puhi paka, ʻoiai inā he mau maʻi ko lākou me ka hoʻololi ʻana o ke kino. ʻO ka noiʻi 2020 i paʻi ʻia ma ka *Journal of Thoracic Oncology* ʻike ʻaʻole i loaʻa i ka poʻe puhi paka me ka adenocarcinoma holomua a me ka mutations EGFR i ke ola holoʻokoʻa o 38.6 mau mahina me ka hoʻomaʻamaʻa ʻia, hoʻohālikelike ʻia me 26.7 mau mahina no ka poʻe ulaula me nā ʻano like ʻole i mālama ʻia me ka chemotherapy. 1 Lapaʻau Pūʻulu ʻO ke ola holoʻokoʻa (Mahina) ʻAʻole loa ka poʻe puhi paka me EGFR+ Advanced Adenocarcinoma Targeted Therapy 38.6 Nā mea puhi paka me EGFR+ Advanced Adenocarcinoma Chemotherapy 26.7 Puna: 1. Nūpepa o Thoracic Oncology, 2020Ka hopenaʻO ka mālama ʻana i ka maʻi maʻi maʻi ʻaʻai ʻole he kahua e ulu nei me ka hoʻonui ʻana i nā manawa kūpono no nā lāʻau lapaʻau pilikino a maikaʻi. He mea koʻikoʻi ka hoʻomaopopo ʻana i nā ʻano kikoʻī o ka maʻi maʻi maʻi ʻaʻole i puhi ʻia, me nā ʻano o ka maʻi kanesa a me nā hoʻololi genetic maʻamau. He mea nui ka hoʻomau ʻana i ka noiʻi a me nā hoʻokolohua lapaʻau no ka holomua ʻana i ka mālama ʻana i nā poʻe i loaʻa i ka maʻi kanesa ʻaʻole i puhi. ʻO ka ʻimi ʻana i nā ʻōlelo aʻoaʻo lapaʻau loea a me ka ʻimi ʻana i nā koho lapaʻau i loaʻa he mau hana koʻikoʻi i ka mālama ʻana i kēia maʻi.