pae 3a ka mālama ʻana i ka maʻi kanesa

ʻO ka maʻi maʻi maʻi maʻi maʻi pae 3A: Nā koho lapaʻau a me ka nānā ʻana. Hoʻopili mākou i nā ʻano hana lapaʻau like ʻole, e like me ke ʻoki ʻana, ka chemotherapy, radiation therapy, a me ka mea i hoʻopaʻa ʻia i ka lāʻau lapaʻau, e kūkākūkā ana i ko lākou pono, nā hopena ʻaoʻao kūpono, a me ke kūpono no nā ʻano pilikino like ʻole. ʻO ka ʻike i hāʻawi ʻia ma ʻaneʻi no nā kumu hoʻonaʻauao a ʻaʻole pono e pani i ka ʻōlelo aʻoaʻo lapaʻau ʻoihana. E kūkākūkā mau me kāu oncologist no kahi hoʻolālā lapaʻau pilikino.

Papa 3A Ka ma'i ma'i 'a'ai: Nā Koho Lapa'au a me ka Mana'o

ʻĀpana 3A maʻi maʻi maʻi maʻi He luʻi koʻikoʻi i ka oncology, i hōʻike ʻia e ka laha ʻana o ka maʻi maʻi i nā ʻōpū lymph kokoke. He mea koʻikoʻi ka hoʻomaopopo ʻana i nā koho lapaʻau i loaʻa a me kā lākou hopena kūpono no nā maʻi a me ko lākou ʻohana. Ke manaʻo nei kēia alakaʻi e hāʻawi i ka ʻike maopopo a pōkole e pili ana pae 3a ka mālama ʻana i ka maʻi kanesa, e hōʻike ana i ke koʻikoʻi o ka mālama pilikino a me ka hoʻoholo like ʻana me kāu hui mālama ola. E hoʻomanaʻo, no ka hoʻonaʻauao ka ʻike ma aneʻi a ʻaʻole pono e hoʻololi i ke kūkākūkā me nā ʻoihana lapaʻau.

Ka hoʻomaopopo ʻana i ka Papa 3A i ka maʻi maʻi ʻāʻī

Ma mua o ke komo ʻana i ka lāʻau lapaʻau, he mea nui e hoʻomaopopo i nā kikoʻī o pae 3A ma'i 'a'ai. Hōʻike kēia pae i ka laha ʻana o ka maʻi kanesa ma ka ʻaoʻao like o ka umauma e like me ke koko (N2), akā ʻaʻole i nā ʻōpū lymph ma kēlā ʻaoʻao o ka umauma a i ʻole nā ​​wahi mamao. ʻO ke ʻano kikoʻī kikoʻī o ka maʻi maʻi ʻaʻai māmā (ke kelepona liʻiliʻi a i ʻole ka liʻiliʻi liʻiliʻi) hoʻololi nui i nā hoʻolālā lapaʻau. Hana ʻia ka hana pololei ma o nā hoʻokolohua kiʻi e like me ka CT scans, PET scans, a me bronchoscopy, me nā biopsies.

Nā ʻano hana lapaʻau no ka pae 3A o ka maʻi maʻi ʻāʻī

Lapaʻau no pae 3A ma'i 'a'ai ʻO ka maʻamau e pili ana i kahi hui o nā lāʻau lapaʻau, i ʻōlelo pinepine ʻia he multimodal therapy. ʻO ke ala maikaʻi loa e pili ana i nā kumu he nui, me ke olakino holoʻokoʻa o ka mea maʻi, ke ʻano kikoʻī a me kahi o ka ʻōpū, a me ka nui o ke komo ʻana o ka lymph node.

ʻO ka ʻoki ʻana

He koho paha ka ʻoki ʻana no kekahi mau maʻi me pae 3A ma'i 'a'ai, ʻoi aku ka poʻe me nā nodal liʻiliʻi a me ke olakino maikaʻi. Hiki ke ʻano o ka ʻoki ʻana mai ka lobectomy (ka wehe ʻana i kahi ʻōpū o ka ʻōpū) a i ka pneumonectomy (ka wehe ʻana i kahi pūmāmā holoʻokoʻa). ʻO ka ʻoki ʻoki ʻana ka manaʻo e hoʻoneʻe i nā maʻi kanesa ʻike ʻia.

Kemoterapi

He lāʻau lapaʻau ʻo Chemotherapy e hoʻohana i nā lāʻau lapaʻau e pepehi i nā maʻi maʻi maʻi a puni ke kino. Hoʻohana maʻamau ia ma mua o ka ʻoki ʻana (neoadjuvant chemotherapy) e hōʻemi i ke koko a i ʻole ma hope o ke ʻoki ʻana (adjuvant chemotherapy) e hōʻemi i ka pilikia o ka hoʻi hou ʻana. Loaʻa kekahi mau papa hana chemotherapy, a ʻo ke koho e pili ana i nā mea e like me ke ʻano maʻi kanesa a me nā ʻano pilikino o ka mea maʻi. ʻO nā regimens maʻamau ka cisplatin a me ka etoposide, a i ʻole carboplatin a me ka paclitaxel.

Lapaʻau Radiation

Hoʻohana ka lāʻau lapaʻau i ka pāhawewe ikaika nui e pepehi i nā maʻi maʻi maʻi. Hiki ke hoʻohana hoʻokahi a hui pū me nā lāʻau lapaʻau ʻē aʻe. In pae 3A ma'i 'a'ai, hiki ke hoʻohana ʻia ka lāʻau lapaʻau ma mua o ka ʻoki ʻana (neoadjuvant radiotherapy) a i ʻole ma hope o ke ʻoki ʻana (radiotherapy adjuvant), a i ʻole he ʻāpana o ka chemoradiation like. ʻO ka Steeotactic body radiation therapy (SBRT) kahi ʻano kikoʻī loa o ka radiation e hāʻawi ana i nā kiʻekiʻe kiʻekiʻe o ka radiation i ka ʻōpū i kekahi mau kau.

ʻO ka Lapaʻau Kūlohelohe

ʻO nā lāʻau lapaʻau i hoʻopaʻa ʻia he lāʻau lapaʻau e hoʻopaʻa pono i nā maʻi maʻi maʻi me ka ʻole e hōʻino i nā cell maʻamau. Hoʻoholo ʻia ka hoʻohana ʻana i ka lāʻau lapaʻau e ka genetic makeup o ka ʻōpū. No ka laʻana, inā loaʻa i ka tumo nā hoʻololi genetic kikoʻī (e like me EGFR, ALK, ROS1), hiki ke ʻoi aku ka maikaʻi o nā lāʻau lapaʻau e like me EGFR inhibitors a i ʻole ALK inhibitors.

Koho Lapaʻau a me ka Prognosis

ʻO ke koho ʻana i ke ala lapaʻau maikaʻi loa no pae 3A ma'i 'a'ai He kaʻina hana like ia ma waena o ka mea maʻi a me kā lākou hui oncology. Hoʻopili kēia i ka loiloi akahele i ke olakino holoʻokoʻa o ka mea maʻi, nā ʻano o ka ʻōpū, a me nā pono kūpono a me nā pilikia o kēlā me kēia koho lapaʻau. Ka wānana no pae 3A ma'i 'a'ai ʻokoʻa nui ma muli o nā kumu e like me ka histology tumor, ka nui o ke komo ʻana o ka lymph node, a me ka pane o ka mea maʻi i ka mālama ʻana. ʻOiai he paʻakikī ka manaʻo, ua hoʻomaikaʻi maikaʻi ka holomua o ka mālama ʻana i nā helu ola i nā makahiki i hala. He mea koʻikoʻi ke kūkākūkā ʻana i ka wānana me ka ʻoiaʻiʻo me kāu hui mālama ola no ka hoʻoholo ʻana a me ka hoʻolālā no ka wā e hiki mai ana.

Ke koho ʻana i ke kikowaena mālama pono

ʻO ke koho ʻana i kahi kikowaena maʻi maʻi kūpono ka mea nui no ka loaʻa ʻana o ka mālama maikaʻi loa pae 3A ma'i 'a'ai. E ʻimi i nā kikowaena me nā poʻe loea oncologists, nā hui multidisciplinary, ke komo ʻana i nā ʻenehana holomua, a me ka hoʻokō i ka mālama maʻi. E noiʻi a hoʻohālikelike i nā koho like ʻole, me ka nānā ʻana i ko lākou akamai i ka mālama ʻana i ka maʻi maʻi ʻaʻai, a mai hoʻokaʻulua e nīnau i nā nīnau i mea e hōʻoluʻolu ai ʻoe i kāu koho.

No ka ʻike hou aku e pili ana i nā koho lapaʻau maʻi maʻi holomua, e noʻonoʻo paha ʻoe e kelepona Shandong Baofa Cancer Research Institute no ke kukakuka ana. Hāʻawi lākou i kahi ākea o nā lawelawe a me nā ʻenehana ʻokiʻoki e mālama i kēia maʻi paʻakikī. E hoʻomanaʻo e kūkākūkā i nā ʻano āpau o kāu mālama ʻana me kāu hui mālama ola e hana i nā hoʻoholo maikaʻi loa no kou olakino.

Hōʻole: Ua manaʻo ʻia kēia ʻike no nā kumu hoʻonaʻauao wale nō a ʻaʻole pono e manaʻo ʻia he ʻōlelo aʻoaʻo olakino. E kūkākūkā mau me kāu mea mālama ola no ka ʻike a me ka mālama ʻana i kekahi maʻi olakino.