lapaʻau metastatic non small cell lung cancer treatment

Ka Lapaʻau ʻana i ka maʻi maʻi ʻaʻai ʻana o ka maʻi maʻi ʻaʻole liʻiliʻi ʻaʻole metastatic. Ke ʻimi nei mākou i nā holomua hou a me nā noʻonoʻo ʻana no ke koho ʻana i ka hoʻolālā lapaʻau maikaʻi loa e pili ana i nā mea maʻi pākahi. No ka hoʻonaʻauao wale nō kēia ʻike a ʻaʻole pono e manaʻo ʻia he ʻōlelo aʻoaʻo olakino. E kūkākūkā mau me kāu mea mālama ola no ke alakaʻi pilikino.

Ka hoʻomaopopo ʻana i ka maʻi maʻi maʻi maʻi metastatic non-small cell lung

Metastatic non-small cell lung cancer (NSCLC) i ka wā e laha aku ai nā pūnaʻi kanesa mai ka māmā i nā wahi ʻē aʻe o ke kino. He kūlana koʻikoʻi kēia e koi ana i kahi ala multidisciplinary i ka mālama ʻana. ʻO ka papahana lapaʻau kūikawā e pili ana i nā kumu he nui, me ke ʻano a me ka pae o ka maʻi kanesa, ke olakino holoʻokoʻa o ka mea maʻi, a me kahi o nā metastases. He mea koʻikoʻi ka hoʻomaʻamaʻa mua ʻana a me ka mālama kūpono no ka hoʻomaikaʻi ʻana i nā hopena.

Nā Koho Lapaʻau no Metastatic NSCLC

Kemoterapi

He lāʻau lapaʻau maʻamau ka Chemotherapy no metastatic non-small cell lung cancer, ka hoʻohana ʻana i nā lāʻau lapaʻau e pepehi i nā maʻi kanesa. Loaʻa nā ʻano hoʻoponopono chemotherapy ʻokoʻa, a ʻo ke koho e pili ana i nā kumu like ʻole, e like me ke olakino ākea o ka mea maʻi a me ke ʻano kikoʻī o NSCLC. ʻO nā lāʻau lapaʻau maʻamau i hoʻohana ʻia me cisplatin, carboplatin, paclitaxel, a me docetaxel. Hiki ke ʻokoʻa nā hopena ʻaoʻao akā e komo pinepine i ka nausea, luhi, a me ka lauoho lauoho. ʻO ka National Cancer Institute hāʻawi i ka ʻike kikoʻī e pili ana i nā regimen chemotherapy no NSCLC.

ʻO ka Lapaʻau Kūlohelohe

Hoʻohana ʻia ka lāʻau lapaʻau i hoʻopaʻa ʻia i nā maʻi kanesa me kekahi mau hoʻololi genetic. He kūpono loa kēia mau lāʻau lapaʻau i nā poʻe maʻi me ka NSCLC e mālama ana i nā hoʻololi genetic kikoʻī, e like me EGFR, ALK, ROS1, a i ʻole nā ​​hoʻololi BRAF. ʻO nā laʻana o nā lāʻau lapaʻau i manaʻo ʻia ʻo osimertinib (Tagrisso), crizotinib (Xalkori), a me afatinib (Gilotrif). ʻOiai ʻoi aku ka maikaʻi, hiki i nā lāʻau lapaʻau i hoʻopaʻa ʻia ke alakaʻi i nā hopena ʻaoʻao, e like me ka ʻili ʻili, ka maʻi maʻi, a me nā pilikia o ka ate. He mea koʻikoʻi ka hoʻāʻo genetic e ʻike i nā poʻe maʻi e pōmaikaʻi ana i ka lāʻau lapaʻau.

Immunotherapy

Hoʻohana ka Immunotherapy i ka ʻōnaehana pale ʻana o ke kino e hakakā i nā maʻi maʻi maʻi. ʻO kēia mau lāʻau lapaʻau he mea nui i ka mālama ʻana i metastatic non-small cell lung cancer. ʻO nā mea hoʻopaneʻe hoʻopaʻa kino, e like me ka pembrolizumab (Keytruda) a me ka nivolumab (Opdivo), pale i nā protein e pale ai i ka ʻōnaehana pale mai ka hoʻouka ʻana i nā maʻi maʻi maʻi. ʻOiai e hāʻawi ana i nā pane kupaianaha i kekahi mau maʻi, hiki i ka immunotherapy ke loaʻa i nā hopena ʻaoʻao, e like me ka luhi, ka ʻūlū, a me ka mumū. ʻO ke kūpono o ka immunotherapy e pili ana i nā mea e like me ka hōʻike PD-L1 a me ke kaumaha mutational tumor.

Lapaʻau Radiation

Hoʻohana ka lāʻau lapaʻau i nā kukuna ikaika nui e pepehi i nā maʻi maʻi maʻi. Hiki ke hoʻohana ʻia e mālama i nā metastases kūloko a i ʻole e hōʻoluʻolu i nā hōʻailona i hoʻokumu ʻia e ka maʻi kanesa, e like me ka ʻeha a i ʻole ka pilikia hanu. Loaʻa nā ʻano lāʻau lapaʻau like ʻole, e like me ka radiation beam waho a me ka brachytherapy. Hiki i nā hopena ʻaoʻao o ka radiation therapy ke komo i ka ʻili ʻili, ka luhi, a me ka nausea.

Koho Lapaʻau a me nā mea maʻi

Ke koho ʻana i ka hoʻolālā lapaʻau maikaʻi loa no metastatic non-small cell lung cancer pono e loiloi pono i kekahi mau kumu. Hoʻopili kēia i ke olakino holoʻokoʻa o ka mea maʻi, ke kūlana hana, ke kahua a me nā hiʻohiʻona o ka maʻi kanesa, a me ka loaʻa ʻana o nā hoʻololi genetic kikoʻī. ʻO kahi hui multidisciplinary o nā oncologists, radiologists, surgeons, a me nā ʻoihana mālama olakino ʻē aʻe e hui pū me ka hoʻomohala ʻana i kahi hoʻolālā lapaʻau pilikino.

ʻO ka Shandong Baofa Cancer Research Institute (https://www.baofahospital.com/) ua hoʻolaʻa ʻia i ka hoʻolako ʻana i ka mālama maʻi maʻi holomua a me ka noiʻi ʻana, me ka hoʻohana ʻana i ka ʻenehana ʻokiʻoki a me kahi ala hui e hoʻopuka i nā hopena maʻi kūikawā. Hāʻawi lākou i nā lawelawe diagnostic a me ka mālama ʻana no nā ʻano maʻi maʻi like ʻole, me metastatic non-small cell lung cancer.

Noiʻi a me nā kuhikuhi e hiki mai ana

Ke hoʻomau nei ka noiʻi ʻana i ka ʻike a me ka mālama ʻana o metastatic non-small cell lung cancer. Hoʻomohala mau ʻia a loiloi ʻia nā lāʻau lapaʻau hou, immunotherapies, a me nā hui pū ʻana i nā hoʻokolohua lapaʻau. Hāʻawi kēia mau holomua i ka manaʻolana no ka hoʻomaikaʻi ʻana i nā hopena lapaʻau a me ka maikaʻi o ke ola no nā maʻi.

Hōʻole: No ka hoʻonaʻauao wale nō kēia ʻike a ʻaʻole pono e manaʻo ʻia he ʻōlelo aʻoaʻo olakino. E kūkākūkā mau me kāu mea mālama ola no ke alakaʻi pilikino e pili ana i kāu kūlana kikoʻī.