lapaʻau hou non small cell lung cancer treatments

Lapaʻau ʻana no ka maʻi maʻi maʻi maʻi ʻaʻole liʻiliʻi hou

Ke ʻimi nei kēia alakaʻi piha i nā holomua hou loa ma lapa'au hou 'ole li'ili'i ma'i ma'i 'a'ai ma'i 'a'ai. E uhi mākou i nā ʻano lapaʻau like ʻole, e pili ana i nā lāʻau lapaʻau i hoʻopaʻa ʻia, immunotherapy, a me ka chemotherapy, e hāʻawi ana i nā ʻike i ko lākou pono, nā hopena ʻaoʻao, a me ke kūpono no nā ʻano pilikino like ʻole. E aʻo e pili ana i ka ulu ʻana o ka lāʻau lapaʻau NSCLC a pehea e hana mau ai ka poʻe noiʻi i nā koho ʻoi aku ka maikaʻi a me ka liʻiliʻi.

Ka hoʻomaopopo ʻana i ka maʻi maʻi maʻi ʻaʻai liʻiliʻi ʻole (NSCLC)

He aha ka NSCLC?

ʻO ka maʻi maʻi ʻaʻai māmā liʻiliʻi ʻole (NSCLC) ma kahi o 85% o nā maʻi kanesa āpau. He hui ia o nā maʻi maʻi maʻi e ulu ana i loko o ka māmā a ʻike ʻia e nā hiʻohiʻona kelepona ʻokoʻa ma lalo o kahi microscope. He mea koʻikoʻi ka ʻike mua ʻana no ka hoʻomaikaʻi ʻana i nā hopena lapaʻau. ʻO ka pae o ka maʻi maʻi maʻi maʻi e pili nui i nā hoʻoholo lapaʻau a me ka wānana. ʻO ka Shandong Baofa Cancer Research Institute (https://www.baofahospital.com/) he alakaʻi i ke kula, hāʻawi i ka mālama piha a me ka noiʻi i NSCLC.

ʻO ka hoʻopaʻa ʻana a me ka hōʻoia ʻana o NSCLC

He mea koʻikoʻi ka hoʻonohonoho pololei ʻana i ke ala maikaʻi loa lapa'au hou 'ole li'ili'i ma'i ma'i 'a'ai ma'i 'a'ai. Hoʻopili kēia i nā hoʻokolohua like ʻole, me ka scan imaging (CT, PET), biopsies, a me nā hoʻāʻo koko. Hoʻohana mau ʻia ka ʻōnaehana staging TNM e hoʻokaʻawale i ka NSCLC ma muli o ka nui o ka tumo (T), ke komo ʻana o ka lymph node (N), a me ka metastasis (M). ʻO ka ʻike mua ʻana, pinepine ma o nā kānana maʻamau no nā poʻe koʻikoʻi nui, e hoʻomaikaʻi i ka manawa o ka lapaʻau kūleʻa.

Nā Koho Lapaʻau no NSCLC

ʻO ka Lapaʻau Kūlohelohe

ʻO nā lāʻau lapaʻau i hoʻopaʻa ʻia e kālele ana i nā molekole kikoʻī e pili ana i ka ulu ʻana o ka maʻi kanesa. Hiki i kēia mau lāʻau lapaʻau ke ʻoi aku ka maikaʻi a me ka liʻiliʻi o nā hopena ʻaoʻao ma mua o ka chemotherapy maʻamau i kekahi mau maʻi. ʻO nā laʻana e pili ana i nā mea hoʻopaneʻe EGFR (e like me ka gefitinib a me ka erlotinib) a me nā mea hoʻopiʻi ALK (e like me crizotinib). ʻO ke koho ʻana i kahi lāʻau lapaʻau i hoʻopaʻa ʻia ma muli o nā hoʻololi genetic kikoʻī i loaʻa i loko o nā pūnaʻi kanesa.

Immunotherapy

Hoʻohana ka Immunotherapy i ka mana o ka ʻōnaehana pale o ke kino e hakakā ai i ka maʻi kanesa. ʻO nā mea hoʻopaneʻe hōʻoia, e like me ka pembrolizumab a me ka nivolumab, hoʻopaʻa i nā protein e pale ai i ka ʻōnaehana pale mai ka hoʻouka ʻana i nā maʻi maʻi maʻi. Ua hōʻike kēia mau lāʻau lapaʻau i ka kūleʻa kupaianaha i ka mālama ʻana i ka NSCLC, ʻoi aku ka nui o nā maʻi me kekahi mau biomarkers. Hiki i ka Immunotherapy ke loaʻa nā hopena ʻaoʻao like ʻole ma mua o ka chemotherapy, e koi ana i ka nānā pono ʻana e nā limahana lapaʻau.

Kemoterapi

Hoʻohana ʻo Chemotherapy i nā lāʻau lapaʻau e pepehi i nā maʻi kanesa. Hiki ke hoʻohana hoʻokahi a hui pū me nā lāʻau lapaʻau ʻē aʻe. Loaʻa nā ʻano hana chemotherapy like ʻole, i hoʻohālikelike ʻia i nā pono kikoʻī o ka mea maʻi a me ka pae o ko lākou maʻi maʻi. ʻO nā lāʻau lapaʻau maʻamau ka cisplatin, carboplatin, a me paclitaxel. Hiki i ka Chemotherapy ke loaʻa nā hopena ʻaoʻao nui, a ʻo ka mālama ʻana i kēia mau hopena ʻaoʻao he mea koʻikoʻi ia o ka mālama ʻana.

Lapaʻau Radiation

Hoʻohana ka lāʻau lapaʻau i ka hoʻoheheʻe ʻana i ka ikehu kiʻekiʻe e luku ai i nā maʻi maʻi. Hiki ke hoʻohana ʻia e hōʻemi i nā maʻi koko, hoʻomaha i nā hōʻailona, ​​​​a i ʻole e pale i ka hoʻi hou ʻana o ka maʻi kanesa. Loaʻa nā ʻano lāʻau lapaʻau like ʻole, e like me ka radiation beam waho a me ka brachytherapy. Hiki i ka lāʻau lapaʻau ke loaʻa nā hopena ʻaoʻao, ma muli o ka wahi i mālama ʻia a me ke ʻano.

ʻO nā lāʻau lapaʻau e puka mai ana a me ka noiʻi

Nā hoʻokolohua lapaʻau

Hiki i ke komo ʻana i nā hoʻokolohua lapaʻau ke hāʻawi i ke komo i nā mea hou lapa'au hou 'ole li'ili'i ma'i ma'i 'a'ai ma'i 'a'ai ma mua o ka loaʻa ʻana o ka lehulehu. Ke nānā pono ʻia kēia mau hoʻāʻo ʻana a hāʻawi i nā poʻe maʻi i ka manawa kūpono e hāʻawi i nā holomua olakino i ka wā e loaʻa ai ka mālama kūlana kiʻekiʻe. Ke komo ikaika nei nā mea noiʻi ma ka Shandong Baofa Cancer Research Institute i nā hoʻokolohua lapaʻau he nui e ʻimi ana i nā lāʻau lapaʻau no NSCLC.

Nā wai biopsies

ʻO nā biopsies wai kahi ala liʻiliʻi e ʻike a nānā i ka maʻi kanesa. Hoʻopili lākou i ka nānā ʻana i nā laʻana koko no ke kahe ʻana i ka DNA tumor (ctDNA), hiki ke hāʻawi i nā ʻike waiwai i ka genetic makeup o ka maʻi kanesa a alakaʻi i nā hoʻoholo lapaʻau. Hāʻawi kēia ʻenehana hou i nā ala lapaʻau pilikino, e hoʻolālā i nā hoʻolālā lapaʻau e pili ana i nā pono o kēlā me kēia maʻi.

Ke koho ʻana i ka Lapaʻau Pono

ʻO ka maikaʻi loa lapa'au hou 'ole li'ili'i ma'i ma'i 'a'ai ma'i 'a'ai ʻokoʻa ke ala e pili ana i nā kumu he nui, me ke ʻano o ka maʻi kanesa, ke olakino holoʻokoʻa o ka mea maʻi, a me ka hiki ʻana o nā hoʻololi genetic kikoʻī. Hoʻokomo pinepine ʻia kahi hui multidisciplinary o nā oncologists, nā kauā, a me nā ʻoihana mālama olakino ʻē aʻe i ka hoʻomohala ʻana i kahi hoʻolālā lapaʻau pilikino. He mea nui ke kamaʻilio wehe ʻana me kāu mea mālama ola e hōʻoia ʻoe e hoʻomaopopo i kāu mau koho a hoʻoholo i nā hoʻoholo.

Hōʻole: Ua manaʻo ʻia kēia ʻike no nā kumu hoʻonaʻauao wale nō a ʻaʻole pono e manaʻo ʻia he ʻōlelo aʻoaʻo olakino. E kūkākūkā mau me kekahi ʻoihana mālama ola kūpono no ka hōʻoia ʻana a me ka mālama ʻana i kekahi maʻi olakino.