adenocarcinoma kho mob ntsws cancer

Adenocarcinoma yog hom mob ntsws cancer tshaj plaws. Kev kho mob yog nyob ntawm ntau yam, nrog rau theem ntawm tus mob qog noj ntshav, tus neeg mob lub cev noj qab haus huv, thiab kev nyiam ntawm tus kheej. Phau ntawv qhia no muab cov ncauj lus kom ntxaws txog ntau yam adenocarcinoma kho mob ntsws cancer Cov kev xaiv muaj, muab kev nkag siab txog lawv cov txiaj ntsig thiab cov kev mob tshwm sim.Kev nkag siab txog Adenocarcinoma Lung Cancer Dab tsi yog Adenocarcinoma?Adenocarcinoma yog ib hom kab mob qog noj ntshav uas tsis yog me me hauv lub ntsws (NSCLC) uas pib hauv cov qog ua kua hauv lub ntsws. Nws feem ntau tshwm sim hauv thaj tsam sab nraud ntawm lub ntsws. Kev kuaj mob ntxov yog qhov tseem ceeb rau kev ua tau zoo adenocarcinoma kho mob ntsws cancer. Cov Shandong Baofa Cancer Research Institute tau cog lus los txhawb kev nkag siab thiab kev kho mob ntawm cov kab mob nyuaj no.Risk Factors for AdenocarcinomaThaum kev haus luam yeeb yog ib qho kev pheej hmoo loj rau ntau hom mob qog noj ntshav, adenocarcinoma feem ntau pom hauv cov neeg tsis haus luam yeeb dua li lwm hom. Lwm yam kev pheej hmoo muaj xws li: Kev raug radon gas Kev raug mob rau asbestos Tsev neeg keeb kwm ntawm mob ntsws cancer Air pollutionDiagnosis thiab Staging of AdenocarcinomaDiagnostic Tests Ntau qhov kev ntsuam xyuas yog siv los kuaj xyuas adenocarcinoma, suav nrog: Chest X-ray: Muab cov duab pib ntawm lub ntsws. CT Scan: Tsim cov duab ntxaws ntxaws ntawm lub ntsws thiab cov ntaub so ntswg ib puag ncig. PET Scan: Pab txheeb xyuas thaj chaw ntawm kev ua haujlwm metabolic, qhia tias muaj mob qog noj ntshav. Bronchoscopy: Tso cai rau cov kws kho mob pom cov hlab ntsws thiab sau cov ntaub so ntswg. Biopsy: Cov qauv ntaub so ntswg raug tshuaj xyuas nyob rau hauv lub tshuab kuaj kab mob kom paub meej qhov kev kuaj mob.Staging AdenocarcinomaStaging pab txiav txim seb qhov mob qog noj ntshav thiab qhia adenocarcinoma kho mob ntsws cancer. Lub theem yog nyob ntawm: T (Tumor): Qhov loj thiab qhov chaw ntawm cov qog thawj zaug. N (Ntaus): Seb tus mob qog noj ntshav tau kis mus rau cov qog ntshav nyob ze. M (Metastasis): Txawm hais tias tus mob qog noj ntshav tau kis mus rau cov kab mob nyob deb. Cov theem ntawm theem 0 (mob qog noj ntshav hauv tsev) mus rau theem IV (metastatic mob qog noj ntshav). Adenocarcinoma ntsws Cancer kho OptionsQhov zoo tshaj plaws adenocarcinoma kho mob ntsws cancer txoj kev npaj nyob ntawm theem, tus neeg mob qhov kev noj qab haus huv tag nrho, thiab lawv cov kev nyiam. Cov kev kho mob uas muaj xws li: Kev phais phais lub hom phiaj kom tshem tawm cov qog nqaij hlav cancer thiab cov ntaub so ntswg ib puag ncig. Cov kev xaiv phais muaj xws li: Wedge Resection: Tshem tawm ntawm ib qho me me, wedge-puab daim ntawm lub ntsws. Lobectomy: Tshem tawm tag nrho lub lobe ntawm lub ntsws. Pneumonectomy: Kev tshem tawm tag nrho lub ntsws.Surgery feem ntau pom zoo rau lub sijhawm ntxov adenocarcinoma kho mob ntsws cancer Thaum cov qog nyob hauv ib cheeb tsam thiab tus neeg mob noj qab haus huv txaus los ua tus txheej txheem.Radiation TherapyRadiation therapy siv lub zog hluav taws xob ntau los tua cov qog nqaij hlav cancer. Nws tuaj yeem siv tau: Raws li kev kho mob tseem ceeb: Rau cov neeg mob uas tsis tuaj yeem phais. Tom qab phais: Txhawm rau tua cov qog nqaij hlav cancer ntxiv. Kom txo tau cov tsos mob: Xws li mob lossis ua tsis taus pa. Hom kev kho hluav taws xob muaj xws li: Sab nraud Beam Radiation Therapy (EBRT): Radiation yog xa los ntawm lub tshuab sab nraum lub cev. Stereotactic Lub Cev Radiation Therapy (SBRT): Muab cov hluav taws xob ntau ntau rau thaj tsam me me.ChemotherapyChemotherapy siv cov tshuaj tua kab mob qog noj ntshav thoob plaws lub cev. Nws yog feem ntau siv: Ua ntej kev phais: Txo cov qog (neoadjuvant chemotherapy). Tom qab phais: Txhawm rau tua cov qog nqaij hlav cancer ntxiv (adjuvant chemotherapy). Raws li kev kho mob tseem ceeb: Rau qib siab-theem adenocarcinoma.Cov tshuaj chemotherapy siv los kho adenocarcinoma suav nrog cisplatin, carboplatin, pemetrexed, thiab docetaxel.Targeted TherapyTargeted therapy tshuaj tsom rau cov molecules tshwj xeeb (piv txwv li, cov proteins, noob caj noob ces) uas koom nrog hauv kev loj hlob ntawm cov qog nqaij hlav cancer thiab ciaj sia. Cov kev kho no feem ntau siv rau adenocarcinoma nrog rau kev hloov pauv caj ces tshwj xeeb.Piv txwv ntawm kev kho mob muaj xws li: EGFR inhibitors: Erlotinib, gefitinib, afatinib, osimertinib (rau EGFR mutations) ALK inhibitors: Crizotinib, alectinib, ceritinib, brigatinib, lorlatinib (rau ALK rearrangements) ROS1 inhibitors: Crizotinib, entrectinib (rau ROS1 rearrangements) BRAF inhibitors: Dabrafenib, trametinib (rau BRAF kev hloov pauv) Kev kuaj caj ces yog qhov tseem ceeb los txiav txim siab seb tus neeg mob puas tsim nyog rau kev kho mob. Cov Shandong Baofa Cancer Research Institute hais txog qhov tseem ceeb ntawm tus kheej cov tshuaj hauv adenocarcinoma kho mob ntsws cancer.ImmunotherapyImmunotherapy tshuaj pab lub cev tiv thaiv kab mob tiv thaiv kab mob. Lawv ua haujlwm los ntawm kev thaiv cov proteins uas tiv thaiv lub cev tiv thaiv kab mob los ntawm kev tawm tsam cov qog nqaij hlav cancer.Piv txwv ntawm cov tshuaj tiv thaiv kab mob muaj xws li: PD-1 inhibitors: Pembrolizumab, nivolumab PD-L1 inhibitors: Atezolizumab, durvalumabImmunotherapy feem ntau yog siv rau theem siab adenocarcinoma, tshwj xeeb tshaj yog thaum cov qog nqaij hlav cancer qhia PD-L1.Side Effects of TreatmentAll adenocarcinoma kho mob ntsws cancer kev xaiv tuaj yeem ua rau muaj kev phiv. Cov kev mob tshwm sim tshwj xeeb yog nyob ntawm hom kev kho mob, koob tshuaj, thiab tus neeg mob cov lus teb. Cov kev mob tshwm sim muaj xws li: qaug zog xeev siab thiab ntuav Cov plaub hau poob Qhov ncauj qhov ncauj Tsis qab los noj mov Tsis muaj zog tiv thaiv kab mob Nws yog ib qho tseem ceeb los tham txog cov kev mob tshwm sim nrog koj tus kws kho mob thiab tsim ib txoj kev npaj los tswj lawv. Cov Shandong Baofa Cancer Research Institute's Kev kho mob tsom rau txo qis cov kev mob tshwm sim thaum ua kom muaj txiaj ntsig zoo.Clinical TrialsClinical trials yog cov kev tshawb fawb tshawb fawb uas sim tshiab adenocarcinoma kho mob ntsws cancer txoj hauv kev. Cov neeg mob tuaj yeem xav txog kev koom nrog hauv kev sim tshuaj ntsuam xyuas kom nkag mus rau cov kev kho tshiab uas tseem tsis tau muaj dav. Kawm paub ntau ntxiv txog kev tshawb fawb txog kev mob qog noj ntshav ntawm Shandong Baofa Cancer Research Institute.Prognosis and Survival RatesTswv yim rau adenocarcinoma nyob ntawm ntau yam, nrog rau theem ntawm tus mob qog noj ntshav, tus neeg mob txoj kev noj qab haus huv tag nrho, thiab cov lus teb rau kev kho mob. Kev kuaj pom ntxov thiab kev kho mob tuaj yeem txhim kho cov neeg muaj sia nyob tau zoo.Txhua tus neeg muaj sia nyob ntawm lub ntsws cancer feem ntau nthuav tawm raws li 5-xyoo kev ciaj sia, txhais tau tias feem pua ​​​​ntawm cov neeg tseem muaj sia nyob tsib xyoos tom qab kuaj mob. Raws li American Cancer Society, 5-xyoo kev ciaj sia nyob rau txhua theem ntawm mob ntsws cancer yog kwv yees li 25%. Txawm li cas los xij, tus lej no sib txawv nyob ntawm theem ntawm kev kuaj mob. Piv txwv li, 5-xyoo txoj kev ciaj sia rau cov qog nqaij hlav qog nqaij hlav hauv cheeb tsam (mob qog noj ntshav uas tsis tau kis mus rau sab nraud ntawm lub ntsws) yog siab dua rau cov qog nqaij hlav cancer hauv lub ntsws (mob qog nqaij hlav uas tau kis mus rau cov kab mob nyob deb). [Source: American Cancer Society]Ntawm no yog ib lub rooj yooj yim uas qhia txog kwv yees li 5-xyoo kev ciaj sia los ntawm theem: Theem kwv yees 5-xyoo muaj sia nyob Rate Localized (Cancer tsis tau kis tawm sab nraum lub ntsws) 59% Regional (Cancer kis mus rau cov qog nqaij hlav nyob ze) 33% Distant (Cancer tau kis mus rau cov kab mob nyob deb) 6% Tag nrho cov theem 2% Combination yog qhov tseem ceeb xwb Cov txiaj ntsig ntawm tus kheej tuaj yeem sib txawv heev.Living with AdenocarcinomaLiving with adenocarcinoma tuaj yeem nyuaj, tab sis muaj cov peev txheej los pab cov neeg mob thiab lawv tsev neeg daws. Cov peev txheej no suav nrog: Pab pawg Pab Pawg Counseling Palliative care Integrative therapies Kev tswj lub neej noj qab haus huv, suav nrog kev noj zaub mov kom zoo thiab kev tawm dag zog ib txwm, tuaj yeem txhim kho lub neej zoo.Adenocarcinoma kho mob ntsws cancer tau nce siab heev nyob rau hauv xyoo tas los no, muab cov neeg mob zoo dua thiab kev xaiv tus kheej. Kev nkag siab txog tus kab mob, cov kev kho mob uas muaj, thiab cov kev mob tshwm sim uas yuav tshwm sim yog qhov tseem ceeb rau kev txiav txim siab. Nco ntsoov sab laj nrog tus kws kho mob uas tsim nyog los txhim kho qhov zoo tshaj plaws adenocarcinoma kho mob ntsws cancer npaj rau koj tus kheej qhov xwm txheej. Cov Shandong Baofa Cancer Research Institute yog mob siab rau muab kev saib xyuas dav dav thiab kev khuv leej rau cov neeg mob nrog adenocarcinoma.