loj cell mob cancer kho

Loj cell lung cancer (LCLC) yog ib qho kev txhoj puab heev ntawm cov qog nqaij hlav tsis me me (NSCLC). Cov kev kho mob muaj ntau haiv neeg thiab nyob ntawm seb muaj mob qog noj ntshav, kev noj qab haus huv tag nrho, thiab cov neeg mob nyiam. Cov txheej txheem feem ntau suav nrog kev phais, kev kho hluav taws xob, tshuaj khomob, kev kho mob, thiab kev tiv thaiv kab mob. Kev sib xyaw cov kev kho mob feem ntau ua rau cov txiaj ntsig zoo tshaj plaws.Kev nkag siab txog Kev Loj Hlob Loj Loj Dab Tsi yog Mob ntsws Cancer?Loj cell lung cancer (LCLC) yog tus cwj pwm los ntawm cov hlwb loj, txawv txav thaum saib hauv lub tshuab tsom. Nws suav txog kwv yees li 5-10% ntawm tag nrho cov qog nqaij hlav ntsws. Vim nws qhov kev txhoj puab heev, kev tshawb pom ntxov thiab kev kho mob tseem ceeb heev. Nws yog ib hom subtype ntawm NSCLC, txhais tau tias nws coj txawv txawv thiab raug kho txawv dua li cov qog nqaij hlav qog nqaij hlav me me (SCLC). LCLC, ntxiv subtyping tej zaum yuav ua tau kom zoo qhia cov tswv yim kho mob. Cov no suav nrog: Loj cell neuroendocrine carcinoma (LCNEC): Cov subtype no qhia cov yam ntxwv nrog ob qho tib si loj cell ntsws cancer thiab mob ntsws cancer me me. Basaloid carcinoma: Ib tug tsis tshua muaj thiab txhoj puab heev subtype. Lymphoepithelioma zoo li carcinoma: Feem ntau tshwm sim hauv cov tib neeg ntawm cov neeg Esxias qhovntsej thiaj tsis mob thiab feem ntau cuam tshuam nrog tus kab mob Epstein-Barr. Clear cell carcinoma: Cuam tshuam los ntawm cov hlwb uas muaj qhov pom tseeb lossis khoob khoob hauv lub tshuab tsom. loj cell ntsws cancer Feem ntau muaj kev sib xyaw ua ke ntawm kev kuaj duab thiab biopsies. Kev kuaj duab: Chest X-ray: Feem ntau thawj qhov kev kuaj pom tau ua los txheeb xyuas qhov txawv txav hauv lub ntsws. CT Scan (Computed Tomography): Muab cov duab ntxaws ntxiv ntawm lub ntsws thiab cov qauv nyob ib puag ncig, pab txiav txim siab qhov loj thiab qhov chaw ntawm cov qog. PET Scan (Positron Emission Tomography): Tshawb xyuas cov hlwb ua haujlwm metabolically, pab txheeb xyuas cov ntaub so ntswg mob qog noj ntshav thiab txiav txim siab seb mob qog noj ntshav puas kis tau. MRI (Magnetic Resonance Imaging): Tej zaum yuav raug siv los ntsuas kev kis mob qog noj ntshav mus rau lub hlwb lossis tus txha caj qaum. Biopsy: Ib qho piv txwv ntawm cov ntaub so ntswg raug coj mus kuaj nyob rau hauv lub tshuab microscope. Cov txheej txheem biopsy muaj xws li: Bronchoscopy: Ib lub raj nyias nyias nrog lub koob yees duab tau muab tso rau ntawm lub qhov ntswg lossis qhov ncauj mus rau hauv lub ntsws kom pom thiab sau cov ntaub so ntswg. Koob Biopsy: Ib rab koob yog muab tso rau hauv lub hauv siab phab ntsa kom sau cov ntaub so ntswg los ntawm cov qog. Qhov no tuaj yeem ua CT-kev coj ua kom paub meej dua. Kev phais Biopsy: Qee zaum, kev phais yuav tsim nyog kom tau txais cov ntaub so ntswg txaus. Loj Cell Lung Cancer Kev Xaiv Qhov zoo tshaj plaws loj cell mob cancer kho nyob ntawm ntau yam, nrog rau theem ntawm tus mob qog noj ntshav, tus neeg mob qhov kev noj qab haus huv tag nrho, thiab lawv cov kev nyiam. Kev kho mob tej zaum yuav siv ib leeg los yog ua ke.SurgerySurgery feem ntau yog cov kev kho mob uas nyiam rau thaum ntxov loj cell ntsws cancer thaum cov qog nyob hauv zos thiab tuaj yeem raug tshem tawm tag nrho. Cov kev xaiv phais muaj xws li: Wedge Resection: Tshem tawm ntawm ib qho me me, wedge-shaped ntawm lub ntsws uas muaj cov qog. Segmentectomy: Tshem tawm ntawm ib feem loj ntawm lub ntsws tshaj li ib tug wedge resection. Lobectomy: Tshem tawm tag nrho lub lobe ntawm lub ntsws. Pneumonectomy: Kev tshem tawm tag nrho lub ntsws.Peb tus khub, Shandong Baofa Cancer Research Institute, at baofahospital.com, tshwj xeeb hauv cov txheej txheem phais tshiab rau kev mob ntsws cancer.Radiation TherapyRadiation therapy siv lub zog hluav taws xob ntau los tua cov qog nqaij hlav cancer. Nws tuaj yeem siv los ua thawj txoj kev kho mob rau loj cell ntsws cancer thaum kev phais tsis yog ib qho kev xaiv, lossis nws tuaj yeem siv tom qab kev phais kom tua cov qog nqaij hlav cancer ntxiv. Hom kev kho hluav taws xob muaj xws li: Sab nraud Beam Radiation Therapy (EBRT): Radiation yog xa los ntawm lub tshuab sab nraum lub cev. Stereotactic Lub Cev Radiation Therapy (SBRT): Muab cov hluav taws xob ntau ntau rau ib qho me me, qhov tseeb qhov chaw. Brachytherapy (Internal Radiation Therapy): Cov noob hluav taws xob lossis cov xaim hluav taws xob tau muab tso ncaj qha rau hauv lossis ze ntawm cov qog.ChemotherapyChemotherapy siv cov tshuaj tua kab mob qog noj ntshav. Nws yog feem ntau siv rau loj cell ntsws cancer uas tau kis dhau lub ntsws los yog thaum phais tsis tau. Cov tshuaj kws khomob feem ntau yog muab tso rau hauv cov hlab ntsha (los ntawm cov hlab ntsha) lossis ntawm qhov ncauj.Targeted TherapyTargeted therapy tshuaj tsom rau cov molecules tshwj xeeb koom nrog hauv kev loj hlob ntawm cov qog nqaij hlav cancer thiab kev ciaj sia. Cov tshuaj no muaj txiaj ntsig zoo tshaj plaws thaum cov qog nqaij hlav qog noj ntshav muaj qee yam kev hloov caj ces. Cov hom phiaj muaj xws li: EGFR (Epidermal Growth Factor Receptor): Kev hloov pauv hauv EGFR muaj ntau dua hauv qee cov neeg. ALK (Anaplastic Lymphoma Kinase): ALK inhibitors tuaj yeem ua tau zoo rau cov neeg mob ALK-zoo loj cell ntsws cancer. ROS 1: ROS1 inhibitors yog siv rau ROS1-zoo qog hlav.Kuaj rau cov kev hloov pauv no yog qhov tseem ceeb rau kev txiav txim siab seb hom kev kho mob puas tsim nyog. loj cell mob cancer kho.ImmunotherapyImmunotherapy pab lub cev tiv thaiv kab mob tiv thaiv kab mob. Cov tshuaj no ua haujlwm los ntawm kev thaiv cov proteins uas tiv thaiv lub cev tiv thaiv kab mob los ntawm kev tawm tsam cov qog nqaij hlav cancer. Cov tshuaj tiv thaiv kab mob feem ntau yog siv rau qib siab loj cell ntsws cancer.Kev kho mob los ntawm StageThe theem ntawm loj cell ntsws cancer heev cuam tshuam txoj kev kho mob. Theem Ib Hom Kev Kho Hniav Theem I & II (Lub Sij Hawm Thaum Ntxov) Kev phais (lobectomy lossis wedge resection) ua raws li kev siv tshuaj khomob yog tias tsim nyog. Kev kho hluav taws xob yuav raug txiav txim siab yog tias kev phais tsis yog ib qho kev xaiv. Theem III (Locally Advanced) Kev sib xyaw ntawm chemotherapy thiab radiation therapy. Kev phais yuav raug txiav txim siab hauv qee kis. Immunotherapy yuav siv tau tom qab chemoradiation. Theem IV (Metastatic) Chemotherapy, tsom txoj kev kho (yog tias muaj kev hloov pauv tsim nyog), thiab kev siv tshuaj tiv thaiv kab mob. Kev kho hluav taws xob tuaj yeem siv los txo cov tsos mob. Clinical TrialsClinical trials yog cov kev tshawb fawb tshawb fawb uas ntsuas qhov tshiab loj cell mob cancer kho kev xaiv. Kev koom tes hauv kev sim tshuaj ntsuam xyuas yuav muab kev nkag mus rau cov kev kho mob siab thiab pab txhawb kev nce qib hauv kev kho mob qog noj ntshav.PrognosisCov kev mob tshwm sim rau loj cell ntsws cancer Nws txawv nyob ntawm theem ntawm mob qog noj ntshav ntawm kev kuaj mob thiab kev kho mob tau txais. Kev tshawb pom ntxov thiab kev kho mob hnyav tuaj yeem txhim kho cov txiaj ntsig. Kev teem sijhawm ua raws li niaj zaus yog qhov tseem ceeb los saib xyuas kom rov tshwm sim. loj cell ntsws cancer Kev kuaj mob tuaj yeem dhau dhau. Kev txhawb pab pawg, kev tawm tswv yim, thiab kev hloov pauv txoj kev ua neej (xws li txiav luam yeeb thiab tswj kev noj zaub mov zoo) tuaj yeem pab cov neeg mob daws qhov teeb meem ntawm lub cev thiab kev xav ntawm tus kab mob.Tsis lees paub: Cov ntaub ntawv no yog rau kev paub dav dav thiab cov ntaub ntawv xov xwm nkaus xwb, thiab tsis yog cov lus qhia kho mob. Nws yog ib qho tseem ceeb kom sab laj nrog tus kws kho mob uas tsim nyog rau txhua yam kev txhawj xeeb txog kev noj qab haus huv lossis ua ntej txiav txim siab txog koj txoj kev noj qab haus huv lossis kev kho mob. Cov kev xaiv kho mob yuav tsum tau txiav txim los ntawm tus kws kho mob raws li tus neeg mob yam xwm txheej.Cov ntaub ntawv: American Cancer Society: https://www.cancer.org/ National Cancer Institute: https://www.cancer.gov/