Kev kho mob ntsws cancer tshiab 2020

Xyoo 2020, kev nce qib tseem ceeb tau ua hauv kev kho mob qog noj ntshav, suav nrog kev pom zoo rau cov kev kho mob tshiab thiab kev tiv thaiv kab mob, muab cov txiaj ntsig tau zoo dua thiab cov kev coj ua tus kheej rau cov neeg mob. Cov kev tawg no tau muab cov kev xaiv tshiab rau cov uas tawm tsam mob qog noj ntshav, hais txog kev hloov pauv caj ces tshwj xeeb thiab txhawb lub cev tiv thaiv kab mob los tiv thaiv tus kab mob. Kev kho mob ntsws cancer tshiab 20202020 yog ib lub xyoo tseem ceeb hauv kev tawm tsam mob qog noj ntshav. Thaum lub xyoo tau tswj hwm los ntawm kev sib kis thoob ntiaj teb, cov kws tshawb fawb thiab cov kws kho mob txuas ntxiv thawb cov ciam teb ntawm kev xaiv kho mob. Ntau qhov kev cia siab tau tshwm sim, muab kev cia siab rau cov neeg mob thiab kho thaj chaw kho mob ntsws cancer. Shandong Baofa Cancer Research lub koom haum tau ua raws li cov kev nce qib no ze.Tej hom kev kho mob: Precision Medicine AdvancesTargeted therapies, tsim los tawm tsam tej yam tsis muaj zog ntawm cov qog nqaij hlav cancer, pom muaj kev vam meej nyob rau hauv 2020. Cov kev kho no feem ntau ua rau muaj kev phiv tsawg dua li cov tshuaj siv tshuaj khomob vim tias lawv tsom cov qog nqaij hlav cancer ntau dua.Cov kev pom zoo tshiab rau kev loj hlob EGFRmal receptors. feem ntau nyob rau hauv non-small cell lung cancer (NSCLC). Xyoo 2020, EGFR inhibitors tshiab thiab txhim kho tau raug pom zoo, muab kev muaj sia nyob zoo dua rau cov neeg mob uas muaj kev hloov pauv no. Cov tshiab tiam tshiab inhibitors feem ntau kov yeej cov txheej txheem tiv thaiv uas txwv cov txiaj ntsig ntawm cov tshuaj ua ntej. Tshwj xeeb, cov neeg ua haujlwm tsom mus rau EGFR exon 20 qhov kev hloov pauv hloov tau pom tias muaj kev ua haujlwm tau zoo.Piv txwv li, ib tus neeg sawv cev zoo li no yog amivantamab. Cov lus hauv qab no qhia txog cov txiaj ntsig ntawm kev sim tshuaj ntawm amivantamab: Lub Sij Hawm Lub Sij Hawm Zuag Qhia Tag Nrho Cov Lus Teb (ORR) Lub Sijhawm Ua Haujlwm (DoR) Phase I 40% 11.1 lub hlis Source: FDAALK Inhibitors: Nthuav Kev Xaiv Kev Kho MobAnaplastic lymphoma kinase (ALK) rov kho dua yog lwm qhov kev hloov pauv hauv NSCLC. Ob peb ALK inhibitors twb muaj lawm, thiab xyoo 2020, kev tshawb fawb tau tsom mus rau kev kov yeej cov tshuaj tiv thaiv no thiab tsim cov tshuaj tiv thaiv ntau dua. Cov kev kho tshiab ua ke kuj tau tshawb nrhiav los txhim kho cov txiaj ntsig ntawm ALK-positive ntsws cancer.Immunotherapy: Harnessing the Power of the Immune SystemImmunotherapy, uas boosts lub cev tiv thaiv kab mob los tiv thaiv qog noj ntshav, txuas ntxiv mus ua ib qho kev loj hlob ntawm kev kho mob ntsws cancer nyob rau hauv 2020.Checkpoint Inhibitors nyob rau hauv bronier Stages, xws liCheckpoint inhibitors, thiab lwm yam. tau hloov kho kev kho mob ntsws cancer siab heev. Hauv xyoo 2020, kev tshawb fawb tshawb fawb txog kev siv cov tshuaj no hauv cov theem ua ntej ntawm tus kab mob, suav nrog tom qab phais lossis ua ke nrog kev kho mob. Cov kev tshawb fawb no tau pom tias kev siv tshuaj tiv thaiv kab mob tuaj yeem txhim kho kev ciaj sia thiab txo qhov kev pheej hmoo ntawm kev rov tshwm sim hauv qee tus neeg mob.Combination Immunotherapy RegimensResearchers kuj tau tshawb xyuas kev sib txuas cov tshuaj tiv thaiv kab mob sib txawv los txhim kho lawv cov txiaj ntsig. Dual checkpoint blockade, siv ob hom kev tiv thaiv kab mob tiv thaiv kab mob, pom cov lus cog tseg hauv qee cov neeg mob uas tsis teb rau ib tus neeg tiv thaiv kab mob. Cov kev sim tshuaj txuas ntxiv ua kom zoo dua cov kev sib xyaw ua ke no txhawm rau txheeb xyuas cov neeg mob feem ntau yuav tau txais txiaj ntsig.Lub luag haujlwm ntawm Biomarker Kev Ntsuas Cov kev nce qib hauv cov hom phiaj kho mob thiab kev tiv thaiv kab mob tau hais txog qhov tseem ceeb ntawm kev kuaj biomarker hauv ntsws cancer. Hauv xyoo 2020, tau muaj kev qhia ntxiv rau kev sim rau ntau yam kev hloov pauv caj ces thiab PD-L1 qhia los coj kev txiav txim siab kho mob. Txoj hauv kev uas tus kheej no ua kom cov neeg mob tau txais kev kho mob uas tsim nyog thiab zoo tshaj plaws rau lawv cov mob qog noj ntshav tshwj xeeb.Shandong Baofa Cancer Research Institute hais txog qhov tseem ceeb ntawm kev sim ntsuas kom ua tiav cov txiaj ntsig zoo tshaj plaws.Looking Ahead: Cov Lus Qhia Yav Tom NtejCov. Kev kho mob ntsws cancer tshiab 2020 tau ua txoj hauv kev kom muaj kev vam meej ntxiv nyob rau xyoo tom ntej. Kev tshawb fawb tsis tu ncua yog tsom rau kev tsim cov kev kho mob tshiab, txhim kho cov tswv yim tiv thaiv kab mob, thiab txheeb xyuas cov biomarkers tshiab. Lub hom phiaj kawg yog los tsim kho cov kev kho mob zoo dua qub thiab kho tus kheej uas txhim kho cov neeg muaj sia nyob thiab lub neej zoo rau txhua tus neeg mob qog noj ntshav.Conclusion 2020 yog ib xyoo ntawm kev nce qib tseem ceeb hauv kev kho mob ntsws cancer. Kev pom zoo ntawm cov phiaj xwm kho mob tshiab thiab kev tiv thaiv kab mob tiv thaiv kab mob, nrog rau kev nce ntxiv ntawm kev kuaj biomarker, tau hloov pauv thaj chaw ntawm kev kho mob ntsws cancer. Cov kev tawg no muab kev cia siab rau cov neeg mob thiab lawv tsev neeg thiab qhia txog qhov tseem ceeb ntawm kev tshawb fawb txuas ntxiv thiab kev tsim kho tshiab hauv kev tawm tsam tus kab mob loj heev no. Xav txog kev mus xyuas Shandong Baofa Cancer Research Institute's lub vev xaib kom paub ntau ntxiv txog kev sim tshuaj thiab kev kho mob qog noj ntshav siab.