kev kho mob ntsws cancer tsis me

Kev kho mob ntsws cancer uas tsis yog me me (NSCLC) cov kev xaiv muaj ntau haiv neeg thiab nyob ntawm theem, subtype, thiab tus neeg mob yam xwm txheej. Cov kev kho mob feem ntau suav nrog kev phais, kev kho hluav taws xob, tshuaj khomob, kev kho mob, thiab kev tiv thaiv kab mob, feem ntau siv ua ke. Phau ntawv qhia no tshawb txog txhua qhov kev xaiv kom ntxaws, pab koj nkag siab txog qhov muaj peev xwm thiab txiav txim siab paub txog kev sab laj nrog koj pab neeg saib xyuas kev noj qab haus huv.Kev nkag siab tsis yog-Small Cell Lung Cancer (NSCLC) NSCLC yog dab tsi?Mob ntsws cancer tsis yog me me (NSCLC) yog hom mob ntsws cancer ntau tshaj plaws, suav txog li 80-85% ntawm tag nrho cov mob ntsws cancer. Nws yog lub ntsiab lus lub kaus uas suav nrog ntau hom subtypes, feem ntau yog adenocarcinoma, squamous cell carcinoma, thiab loj cell carcinoma.NSCLC StagingThe theem ntawm NSCLC yog qhov tseem ceeb rau kev txiav txim siab txoj kev kho zoo tshaj plaws. Cov theem yog txiav txim los ntawm qhov loj thiab qhov chaw ntawm cov qog, seb nws puas tau kis mus rau cov qog nqaij hlav nyob ze, thiab seb nws puas tau metastasized rau cov kab mob nyob deb. Lub hom phiaj yog tshem tawm cov qog thiab cov qog nqaij hlav nyob ze uas yuav muaj cov qog nqaij hlav cancer. Lobectomy: Tshem tawm tag nrho lub lobe ntawm lub ntsws. Pneumonectomy: Kev tshem tawm tag nrho lub ntsws. Wedge Resection: Tshem tawm ntawm ib qho me me, wedge-shaped piece ntawm lub ntsws. Segmentectomy: Kev tshem tawm ntawm ib ntu ntawm lub ntsws, uas loj dua li ib qho kev phais tab sis me dua li lub lobectomy.Nco tseg: Kev phais yuav tsis yog ib qho kev xaiv rau cov neeg mob uas muaj NSCLC siab heev los yog cov uas muaj lwm yam mob uas ua rau kev phais muaj kev pheej hmoo heev.Radiation TherapyRadiation therapy siv cov hluav taws xob hluav taws xob siab los tua cov qog nqaij hlav cancer. Nws tuaj yeem siv los kho NSCLC hauv ntau txoj hauv kev: Sab nraud Beam Radiation Therapy (EBRT): Radiation yog xa los ntawm lub tshuab sab nraum lub cev. Stereotactic Lub Cev Radiation Therapy (SBRT): Ib daim ntawv qhia meej heev ntawm EBRT uas xa cov hluav taws xob ntau rau ib cheeb tsam me. Feem ntau siv rau kev mob ntsws cancer thaum ntxov thaum phais tsis ua tau. Brachytherapy: Cov khoom siv hluav taws xob tau muab tso ncaj qha rau hauv lossis ze ntawm lub qog.Radiation therapy tuaj yeem siv ib leeg lossis ua ke nrog lwm yam kev kho mob, xws li tshuaj tua kab mob. Peb ntawm Shandong Baofa Cancer Research Institute nkag siab txog qhov tseem ceeb ntawm kev sib txuas cov kev kho mob kom tau txais txiaj ntsig zoo tshaj plaws. Baofa yog tus thawj coj hauv kev saib xyuas mob qog noj ntshav.ChemotherapyChemotherapy siv tshuaj tua kab mob qog noj ntshav thoob plaws lub cev. Nws yog feem ntau siv los kho NSCLC siab heev lossis tiv thaiv kev mob qog noj ntshav tom qab phais. Cov tshuaj siv tshuaj khomob rau NSCLC suav nrog: Cisplatin Carboplatin Pemetrexed Docetaxel PaclitaxelChemotherapy feem ntau muab rau hauv cov voj voog, nrog rau lub sijhawm kho mob ua raws li lub sijhawm so. Cov kev mob tshwm sim tuaj yeem sib txawv nyob ntawm cov tshuaj siv thiab tus neeg mob.Targeted TherapyTargeted therapy siv cov tshuaj uas tsom rau cov molecules tshwj xeeb koom nrog hauv kev mob qog noj ntshav thiab kev ciaj sia. Cov tshuaj no feem ntau siv tau zoo dua thiab muaj kev phiv tsawg dua li kev siv tshuaj khomob. Cov hom phiaj kho mob feem ntau yog rau cov neeg mob uas muaj kev hloov caj ces tshwj xeeb. Cov hom phiaj muaj xws li: EGFR: Epidermal Growth Factor Receptor ALK: Anaplastic Lymphoma Kinase ROS 1: ROS1 Proto-Oncogene Receptor Tyrosine Kinase BRAF: B-Raf Proto-Oncogene, Serine/Threonine Kinase NTRK: Neurotrophic Tyrosine Receptor KinaseCov piv txwv ntawm cov tshuaj tiv thaiv kev kho mob siv rau NSCLC suav nrog: Gefitinib (Iressa) Erlotinib (Tarceva) Afatinib (Gilotrif) Osimertinib (Tagrisso) Crizotinib (Xalkori) Ceritinib (Zykadia) AlectinibBeforeen txoj kev kho mob hauv qab no Kev ntsuam xyuas caj ces los txiav txim seb lawv puas muaj kev hloov pauv.ImmunotherapyImmunotherapy siv cov tshuaj los pab lub cev tiv thaiv kab mob tiv thaiv kab mob. Cov tshuaj no tuaj yeem thaiv cov protein uas tiv thaiv lub cev tiv thaiv kab mob los ntawm kev tawm tsam cov qog nqaij hlav cancer. Cov tshuaj tiv thaiv kab mob rau NSCLC suav nrog: Pembrolizumab (Keytruda) Nivolumab (Opdivo) Atezolizumab (Tecentriq) Durvalumab (Imfinzi) Immunotherapy tuaj yeem siv ib leeg lossis ua ke nrog kev kho mob lossis lwm yam kev kho mob. Kev mob tshwm sim tuaj yeem suav nrog qaug zog, ua pob khaus tawv nqaij, thiab mob ntawm ntau yam kabmob.NSCLC Kev Kho Mob los ntawm StageStage I NSCLCSurgery feem ntau yog thawj txoj kev kho mob rau theem I NSCLC. SBRT yuav raug txiav txim siab yog tias tus neeg mob tsis yog tus neeg thov kev phais.Stage II NSCLCTreatment rau Theem II NSCLC feem ntau muaj kev phais tom qab siv tshuaj khomob. Kev kho hluav taws xob kuj tseem siv tau.Stage III NSCLCTreatment rau Theem III NSCLC yog qhov nyuaj dua thiab tuaj yeem koom nrog kev phais, kws khomob, thiab kev kho hluav taws xob. Immunotherapy kuj tseem siv tau tom qab chemoradiation hauv qee kis.Stage IV NSCLCTreatment for Stage IV NSCLC tsom rau kev tswj kev loj hlob ntawm cov qog nqaij hlav thiab txo cov tsos mob. Cov kev xaiv yuav suav nrog kev kho mob, kev kho mob, kev tiv thaiv kab mob, thiab kev kho hluav taws xob. Kev xaiv kev kho mob yog nyob ntawm cov yam ntxwv tshwj xeeb ntawm tus mob qog noj ntshav thiab tus neeg mob tag nrho kev noj qab haus huv.Clinical TrialsClinical trials yog cov kev tshawb fawb tshawb fawb uas kuaj cov kev kho mob tshiab. Cov neeg mob nrog NSCLC tuaj yeem tsim nyog koom nrog hauv kev sim tshuaj. Tham nrog koj tus kws kho mob kom paub ntau ntxiv txog kev sim tshuaj thiab seb lawv puas yog rau koj. Shandong Baofa Cancer Research Institute's Kev cog lus rau kev tshawb fawb txhais tau tias peb nyob ntawm qhov txiav ntawm cov kev xaiv kho tshiab, qee zaum dhau los ntawm kev sim tshuaj kho mob.Kev txiav txim siab txog kev kho mob xaiv txoj kev kho mob rau NSCLC yog qhov kev txiav txim siab nyuaj uas yuav tsum tau tham nrog koj pab neeg kho mob. Cov yam tseem ceeb uas yuav tsum xav txog suav nrog theem thiab hom kab mob qog noj ntshav, tus neeg mob txoj kev noj qab haus huv tag nrho, thiab lawv cov kev nyiam. Tsis txhob ua siab deb nug cov lus nug thiab nrhiav lub tswv yim thib ob yog tias xav tau.Prognosis and Survival RatesSurvival rates for NSCLC nws txawv nyob ntawm theem ntawm mob qog noj ntshav, kev kho mob tau txais, thiab lwm yam. Kev tshawb pom ntxov thiab kev kho mob tuaj yeem txhim kho txoj hauv kev muaj sia nyob. Theem 5-Year Survival Rate Theem I 68-92% Theem II 53-60% Theem III 13-36% Theem IV Tsawg dua 10% *Source: American Cancer Society (www.cancer.org) Nyob nrog NSCLCLiving nrog NSCLC tuaj yeem nyuaj, tab sis muaj ntau yam kev pab cuam los pab cov neeg mob thiab lawv tsev neeg daws. Cov peev txheej no suav nrog pab pawg txhawb nqa, kev pab sab laj, thiab kev pab nyiaj txiag.