kev kho mob ntsws cancer kho tshiab 2020

Kev kho mob ntsws cancer tshiab: 2020 thiab Tshaj

Kab lus no muab cov ntsiab lus ntawm kev nce qib tseem ceeb hauv kev kho mob ntsws cancer kho tshiab 2020 thiab tshaj. Peb tshawb nrhiav cov kev txhim kho tseem ceeb hauv cov hom phiaj kho mob, immunotherapies, thiab lwm yam kev hloov tshiab, tsom mus rau lawv cov kev ua tau zoo thiab muaj feem cuam tshuam rau cov neeg mob tau txais txiaj ntsig. Kawm paub txog cov kev tshawb fawb tshiab thiab kev sim tshuaj kho mob txuas ntxiv mus tsim kho lub neej yav tom ntej ntawm kev kho mob ntsws cancer.

Kev Kho Mob Hom Phiaj: Cov Tshuaj Kho Mob Precision Siv Qhov Chaw Nruab Nrab

Kev nce qib hauv EGFR thiab ALK Inhibitors

Kev nce qib tseem ceeb tau ua tiav hauv cov kev kho mob, tshwj xeeb tshaj yog rau cov neeg mob uas muaj kev hloov pauv caj ces. Kev kho mob ntsws cancer kho tshiab 2020 pom qhov kev pom zoo ntawm ntau yam tshiab EGFR thiab ALK inhibitors, muab kev txhim kho kev ua tau zoo thiab kev ua kom ntev dua piv rau cov tiam dhau los. Cov tshuaj no xaiv hom mob qog noj ntshav nrog cov kev hloov pauv no, txo qis kev puas tsuaj rau cov ntaub so ntswg noj qab haus huv. Piv txwv li, txoj kev loj hlob ntawm peb tiam EGFR inhibitors tau pom cov lus cog tseg hauv kev kov yeej cov kev kho mob yav dhau los. Kev tshawb fawb ntxiv txuas ntxiv mus tshawb txog lub peev xwm ntawm cov phiaj xwm kev kho mob no nrog rau lwm cov kev kho mob.

Immunotherapies: Siv lub zog ntawm lub cev tiv thaiv kab mob

Checkpoint Inhibitors thiab lawv lub luag haujlwm hauv kev kho mob ntsws cancer

Immunotherapies, uas siv lub cev lub cev tiv thaiv kab mob los tiv thaiv qog noj ntshav, tau hloov pauv. kev kho mob ntsws cancer kho tshiab 2020. Checkpoint inhibitors, xws li PD-1 thiab PD-L1 inhibitors, tau ua pov thawj zoo kawg li hauv kev nthuav dav txoj sia nyob hauv cov neeg mob uas mob qog noj ntshav siab. Cov tshuaj no thaiv cov cim qhia tias cov qog nqaij hlav cancer siv los tiv thaiv lub cev tiv thaiv kab mob, tso cai rau lub cev tiv thaiv kab mob los tua thiab rhuav tshem cov qog. Txawm li cas los xij, tsis yog txhua tus neeg mob teb rau kev tiv thaiv kab mob, thiab kev tshawb fawb txuas ntxiv txhawm rau txheeb xyuas biomarkers los twv seb cov neeg mob twg yuav tau txais txiaj ntsig zoo tshaj plaws. Tsis tas li ntawd, cov kev tshawb fawb tab tom tshawb nrhiav kev siv cov tshuaj tiv thaiv kab mob ua ke nrog lwm cov kev kho mob, xws li kev kho tshuaj khomob lossis kev kho mob, txhawm rau txhim kho kev ua tau zoo.

Lwm Txoj Kev Cia Siab

Cov Kev Kho Mob Tshiab thiab Kev Kho Mob Nthuav Tawm

Tshaj li cov hom phiaj kho mob thiab kev tiv thaiv kab mob tiv thaiv kab mob, ntau lwm yam kev cog lus tau raug tshawb xyuas rau kev kho mob ntsws cancer kho tshiab 2020. Cov no suav nrog cov tshuaj khomob tshiab, kev kho mob hluav taws xob ua ntej (xws li stereotactic body radiotherapy lossis SBRT), thiab cov tshuab xa tshuaj tshiab. Ntau qhov kev sim tshuaj tau tab tom ua, ntsuas qhov ua tau zoo ntawm cov kev kho tshiab no thiab tshawb nrhiav cov kev sib txuas ua ke los ua kom tau txais txiaj ntsig zoo. Kev paub txog cov kev sim tshuaj tsis tu ncua yog qhov tseem ceeb rau cov neeg mob thiab lawv tsev neeg nrhiav kev kho mob siab tshaj plaws. ClinicalTrials.gov yog ib qho chaw muaj txiaj ntsig rau kev nrhiav cov ntaub ntawv ntawm kev sim siab tam sim no.

Lub neej yav tom ntej ntawm kev kho mob ntsws cancer

Cov toj roob hauv pes ntawm kev kho mob ntsws cancer yog hloov zuj zus mus tas li, nrog kev tshawb fawb thiab kev loj hlob tsis tu ncua thawb cov ciam teb ntawm qhov ua tau. Kev sib koom ua ke ntawm cov tshuaj precision, immunotherapy, thiab lwm yam tshiab txoj hauv kev tuav cov lus cog tseg zoo kawg nkaus rau kev txhim kho cov neeg mob tau txais txiaj ntsig thiab muaj sia nyob. Nws yog ib qho tseem ceeb rau cov tib neeg uas ntsib kev mob ntsws cancer los sab laj nrog lawv tus kws kho mob oncologist los tham txog cov tswv yim kho mob uas tsim nyog tshaj plaws raws li lawv qhov xwm txheej tshwj xeeb thiab cov caj ces. Rau kev saib xyuas mob qog noj ntshav, xav txog kev tshawb nrhiav cov kws tshaj lij muaj nyob hauv cov tsev kawm xws li Shandong Baofa Cancer Research Institute.

Cov ntaub ntawv sib piv: Cov Kev Kho Mob Tseem Ceeb Ua Ntej ()

Hom Kev Kho Mob	Qhov tseem ceeb nce qib	Kev cuam tshuam rau tus neeg mob tshwm sim
EGFR Inhibitors	Third-generation inhibitors (piv txwv li osimertinib)	Txhim kho kev vam meej-tsis muaj sia nyob thiab tag nrho cov ciaj sia nyob hauv qee cov neeg mob.
Immunotherapy (PD-1 / PD-L1 inhibitors)	Kev siv ntau ntxiv hauv cov chaw kho mob thawj zaug.	Kev txhim kho tseem ceeb hauv kev ciaj sia rau cov neeg mob tshwj xeeb.

Nco tseg: Cov ntaub ntawv no yog rau kev paub dav dav thiab cov ntaub ntawv xov xwm nkaus xwb, thiab tsis yog cov lus qhia kho mob. Nco ntsoov sab laj nrog tus kws kho mob tsim nyog rau txhua yam kev txhawj xeeb txog kev noj qab haus huv lossis ua ntej txiav txim siab txog koj txoj kev noj qab haus huv lossis kev kho mob.