kev kho mob uas tsis yog me me ntawm lub ntsws cancer kev kho mob

Kev Xaiv Kev Kho Mob rau Non-Me Me Cell Lung Cancer (NSCLC) To taub Cov Tsis-Small Cell Lung Cancer thiab Muaj Kev Kho Mob Cov kab lus no muab cov ntaub ntawv qhia txog kev kho mob uas tsis yog-me me hauv lub ntsws (NSCLC). Peb tshawb nrhiav ntau yam kev kho mob, suav nrog kev phais, kws khomob, kev kho hluav taws xob, kev kho lub hom phiaj, thiab kev siv tshuaj tiv thaiv kab mob, qhia txog lawv cov txiaj ntsig thiab cov kev mob tshwm sim. Peb lub hom phiaj los txhawb cov tib neeg ntsib qhov kev kuaj mob no nrog kev paub los pab txhawb kev sib tham nrog lawv cov kws kho mob. Nco ntsoov, cov ntaub ntawv no yuav tsum tsis txhob hloov cov lus qhia kws kho mob. Nco ntsoov sab laj nrog koj tus kws kho mob oncologist lossis lwm tus kws kho mob tsim nyog rau kev taw qhia tus kheej.

Nkag siab Tsis yog-Small Cell Lung Cancer (NSCLC)

Non-small cell ntsws cancer (NSCLC) suav txog kwv yees li 85% ntawm tag nrho cov kev kuaj mob ntsws cancer. Nws yog ib hom kab mob heterogeneous, txhais tau hais tias nws nthuav tawm txawv ntawm ntau tus neeg, cuam tshuam rau kev kwv yees thiab kev kho mob. Kev kuaj pom thaum ntxov ua rau muaj txiaj ntsig zoo dua qub, qhia txog qhov tseem ceeb ntawm kev tshuaj ntsuam xyuas tsis tu ncua thiab kho mob sai yog tias cov tsos mob tshwm sim. Hom thiab theem ntawm NSCLC cuam tshuam rau txoj kev kho mob.

Staging ntawm NSCLC

Lub staging ntawm NSCLC, feem ntau siv TNM system (Tumor, Node, Metastasis), yog qhov tseem ceeb hauv kev txiav txim siab txog kev kho mob. Cov txheej txheem no ntsuas cov qog qhov loj thiab qhov chaw, kev koom tes ntawm cov qog nqaij hlav, thiab muaj cov metastases nyob deb. Cov theem ntawm I (localized) mus rau IV (metastatic), nrog rau txhua theem qhia txog kev sib txawv thiab kev kho mob. Precise staging yuav tsum muaj kev sib xyaw ua ke ntawm cov kev ntsuam xyuas zoo li CT scans, PET scans, thiab muaj peev xwm ua rau biopsies.

Kev Xaiv Kev Kho Mob rau NSCLC

Kev xaiv kev kho mob rau NSCLC nyob ntawm ntau yam ntawm cov qog nqaij hlav cancer, tus neeg mob qhov kev noj qab haus huv tag nrho, thiab kev nyiam ntawm tus kheej. Nws feem ntau suav nrog kev sib xyaw ua ke ntawm kev kho mob kom ua tau zoo thiab txhim kho cov txiaj ntsig.

Kev phais

Kev phais tshem tawm ntawm cov qog yog ib qho kev kho mob tseem ceeb rau theem pib NSCLC. Hom kev phais nyob ntawm tus qog qhov chaw thiab qhov loj me, muaj feem cuam tshuam nrog lobectomy (tshem tawm ntawm lub ntsws lobe), pneumonectomy (tshem tawm tag nrho lub ntsws), lossis segmentectomy (tshem tawm ntawm lub ntsws me dua). Cov txheej txheem phais mob me me xws li kev phais mob thoracoscopic video (VATS) muaj ntau zuj zus, muab cov kev txiav me me thiab lub sijhawm rov qab sai dua.

Tshuaj kho mob

Kev kho mob yog siv tshuaj tua kab mob qog noj ntshav. Nws feem ntau yog siv ua ke nrog lwm yam kev kho mob, xws li kev phais lossis kev kho hluav taws xob, lossis kev kho thawj zaug rau theem siab. NSCLC. Feem ntau siv cov tshuaj chemotherapy rau NSCLC xws li cisplatin, carboplatin, paclitaxel, thiab docetaxel. Kev mob tshwm sim tuaj yeem yog qhov tseem ceeb thiab sib txawv nyob ntawm cov tshuaj tshwj xeeb thiab ntau npaum li cas.

Kev kho hluav taws xob

Kev kho hluav taws xob siv hluav taws xob hluav taws xob ntau los tua cov qog nqaij hlav cancer. Nws tuaj yeem siv los txo cov qog ua ntej kev phais, rhuav tshem cov qog nqaij hlav cancer tom qab phais, lossis kho cov theem siab NSCLC uas tsis tuaj yeem phais tshem tawm. Sab nrauv kab hluav taws xob kho mob yog hom kev tshaj tawm, xa hluav taws xob los ntawm lub tshuab sab nraud lub cev. Kev mob tshwm sim tuaj yeem suav nrog qaug zog, khaus tawv nqaij, thiab xeev siab.

Hom Kev Kho Mob

Cov phiaj xwm kho mob tsom rau cov molecules tshwj xeeb koom nrog hauv kev loj hlob ntawm cov qog nqaij hlav cancer thiab kev ciaj sia. Lawv muaj txiaj ntsig tshwj xeeb rau NSCLC Cov neeg mob uas muaj kev hloov pauv caj ces, xws li EGFR, ALK, ROS1, thiab BRAF kev hloov pauv. Cov kev kho mob no tau pom tias muaj kev vam meej zoo tshaj plaws hauv kev ncua sij hawm muaj sia nyob rau cov neeg mob uas muaj kev hloov pauv tshwj xeeb. Piv txwv ntawm kev kho mob muaj xws li erlotinib, gefitinib, crizotinib, thiab afatinib.

Immunotherapy

Immunotherapy siv lub cev lub cev tiv thaiv kab mob los tua cov qog nqaij hlav cancer. Nws muaj txiaj ntsig tshwj xeeb hauv kev kho mob NSCLC nrog siab PD-L1 qhia. Cov tshuaj tiv thaiv kab mob, xws li pembrolizumab, nivolumab, thiab atezolizumab, thaiv cov tshuaj tiv thaiv kab mob, tso cai rau lub cev tiv thaiv kab mob los tua cov qog nqaij hlav cancer. Cov kev mob tshwm sim tuaj yeem sib txawv tab sis tuaj yeem suav nrog kev qaug zog, ua pob khaus tawv nqaij, thiab cov xwm txheej tsis zoo cuam tshuam txog kev tiv thaiv kab mob.

Xaiv Txoj Kev Npaj Kho Mob Zoo

Kev xaiv ntawm NSCLC kev kho mob yog tus txheej txheem ntawm tus kheej heev. Txoj hauv kev zoo yog nyob ntawm ntau yam, suav nrog hom tshwj xeeb thiab theem ntawm mob qog noj ntshav, tus neeg mob txoj kev noj qab haus huv tag nrho, thiab kev nyiam ntawm tus kheej. Kev sib raug zoo ntawm tus neeg mob thiab lawv pab neeg saib xyuas kev noj qab haus huv yog qhov tseem ceeb los txiav txim siab txog txoj haujlwm zoo tshaj plaws. Kev sib tham nrog cov kws kho mob oncologist thiab lwm tus kws kho mob tshwj xeeb, suav nrog cov kws phais mob, kws kho mob hluav taws xob, thiab kws kho mob oncologist, yog qhov tseem ceeb los tsim cov phiaj xwm kho mob. Qhov no yuav tsum tsis yog tsuas yog kho nws tus kheej xwb tab sis kuj yog ib txoj kev npaj los tswj cov kev mob tshwm sim.

Hom Kev Kho Mob	Kev ua tau zoo	Cov teebmeem
Kev phais	Siab rau theem pib	Mob, kab mob, ua pa nyuaj
Tshuaj kho mob	Nws txawv nyob ntawm theem thiab tshuaj	xeev siab, ntuav, plaub hau poob, qaug zog
Kev kho hluav taws xob	Siv tau rau cov kab mob hauv zos	qaug zog, tawv nqaij khaus, xeev siab
Hom Kev Kho Mob	Muaj txiaj ntsig zoo rau kev hloov pauv tshwj xeeb	Cov tawv nqaij ua pob khaus, raws plab, qaug zog
Immunotherapy	Siv tau rau tej hom thiab theem	Kev qaug zog, ua pob khaus tawv nqaij, tiv thaiv kab mob tsis zoo

Yog xav paub ntxiv txog kev kho mob qog noj ntshav thiab kev txhawb nqa, thov mus saib hauv Shandong Baofa Cancer Research Institute lub vev xaib. Lawv muab cov kev kho mob siab heev thiab kev txhawb nqa dav dav rau cov tib neeg tawm tsam mob qog noj ntshav.

Disclaimer: Cov ntaub ntawv no yog tsim los rau kev kawm nkaus xwb thiab yuav tsum tsis txhob suav hais tias yog cov lus qhia kho mob. Nco ntsoov sab laj nrog ib tus kws kho mob uas tsim nyog rau kev kuaj mob thiab kho txhua yam mob.

Cov ntaub ntawv pov thawj: (Cov ntaub ntawv tshwj xeeb rau cov ntawv kho mob thiab cov koom haum mob qog noj ntshav muaj npe yuav suav nrog ntawm no, txuas rau lawv nrog rel=nofollow kom tsis txhob cuam tshuam kev tshawb fawb qeb. Piv txwv yuav suav nrog National Cancer Institute (NCI) thiab American Cancer Society (ACS) lub vev xaib.)