nnukwu ọgwụgwọ ọrịa kansa akpa ume cell

Ọrịa cancer akpa ume cell buru ibu (LCLC) bụ ụdị ọrịa cancer akpa ume na-abụghị obere cell (NSCLC). Nhọrọ ọgwụgwọ dị iche iche ma dabere na ọkwa ọrịa kansa, ahụike zuru oke, na mmasị ndị ọrịa. Ụzọ ndị a na-emekarị gụnyere ịwa ahụ, ọgwụgwọ radieshon, chemotherapy, ọgwụgwọ ezubere iche, na immunotherapy. Ijikọta ọgwụgwọ na-arụpụtakarị nsonaazụ kacha mma. Ịghọta nnukwu ọrịa kansa akpa ume cell Gịnị bụ nnukwu ọrịa cancer akpa ume?Ọrịa cancer akpa ume cell buru ibu (LCLC) e ji nnukwu mkpụrụ ndụ na-adịghị mma mara mgbe a na-ele ya n'okpuru microscope. Ọ bụ ihe dịka 5-10% nke ọrịa cancer akpa ume niile. N'ihi ọdịdị ike ike ya, nchọpụta mmalite na ọgwụgwọ dị oke mkpa. Ọ bụ ụdị nke NSCLC, nke pụtara na ọ na-akpa àgwà dị iche iche na a na-emeso ya dị iche iche karịa obere ọrịa cancer akpa ume cell (SCLC).Ụdị Ọrịa cancer akpa ume nke ukwuu LCLC, enwere ike ịme ntinye ederede ọzọ iji nweta usoro ọgwụgwọ ka mma. Ndị a gụnyere: Nnukwu cell neuroendocrine carcinoma (LCNEC): Ụdị nke a na-ekekọrịta njirimara na ha abụọ nnukwu cell akpa ume cancer na obere ọrịa kansa akpa ume cell. Basaloid carcinoma: Ụdị dị ụkọ na nke na-eme ihe ike. Lymphoepithelioma dị ka carcinoma: Nke a na-ahụkarị na ndị sitere na Eshia ma na-ejikọta ya na nje Epstein-Barr. Kpochapụ carcinoma cell: Ejiri mkpụrụ ndụ nwere ọdịdị doro anya ma ọ bụ ihe efu n'okpuru microscope. Nchọpụta ọrịa cancer akpa ume buru ibu. nnukwu cell akpa ume cancer na-agụnyekarị nchikota nke nyocha onyonyo na biopsies. Nnwale onyonyo: X-ray nke obi: Ọtụtụ mgbe, a na-enyocha onyonyo nke mbụ iji chọpụta ihe na-adịghị mma na ngụgụ. Nyocha CT ( Tomography gbakọọ): Na-enye nkọwa zuru ezu nke ngụgụ na ihe ndị gbara ya gburugburu, na-enyere aka ịchọpụta nha na ọnọdụ nke etuto ahụ. Nyocha PET (Positron Emission Tomography): Na-achọpụta mkpụrụ ndụ metabolic na-arụ ọrụ, na-enyere aka ịchọpụta anụ ahụ na-egbu egbu ma chọpụta ma ọrịa kansa agbasawo. MRI (ihe onyonyo resonance magnet): Enwere ike iji chọpụta mgbasa nke ọrịa kansa na ụbụrụ ma ọ bụ ọkpụkpụ azụ. Biopsy: A na-ewere ihe nlele anụ ahụ maka nyocha n'okpuru microscope. Usoro biopsy gụnyere: Bronchoscopy: A na-etinye tube dị gịrịgịrị, na-agbanwe agbanwe nke nwere igwefoto site na imi ma ọ bụ ọnụ n'ime ngụgụ iji hụ anya wee nakọta ihe nlele anụ ahụ. Biopsy agịga: A na-etinye agịga n'ahụ mgbidi obi iji nweta ihe nlele anụ ahụ site na etuto ahụ. Enwere ike iduzi CT maka nkenke karịa. Biopsy ịwa ahụ: N'ọnọdụ ụfọdụ, ịwa ahụ nwere ike ịdị mkpa iji nweta nlele anụ ahụ zuru oke. Nhọrọ ọgwụgwọ ọrịa cancer akpa ume buru ibu nke kacha mma nnukwu ọgwụgwọ ọrịa kansa akpa ume cell dabere n'ọtụtụ ihe, gụnyere ọkwa nke ọrịa kansa, ahụike zuru oke nke onye ọrịa, na mmasị ha. Enwere ike iji nhọrọ ọgwụgwọ naanị ma ọ bụ jikọtara ya. Ịwa ahụ na-abụkarị ọgwụgwọ kachasị mma maka mmalite mmalite. nnukwu cell akpa ume cancer mgbe a na-ahụ maka etuto ahụ ma nwee ike iwepụ ya kpamkpam. Nhọrọ ịwa ahụ gụnyere: Ndozi wedge: Mwepụ nke obere akụkụ akpa ume nwere etuto ahụ. Akụkụ: Mwepụ akụkụ ka ukwuu nke ngụgụ karịa mwepu wedge. Lobectomy: Mwepụ nke otu lobe nke ngụgụ. Pneumonectomy: Mwepụ nke ngụgụ dum. Onye ibe anyị, Shandong Baofa Cancer Research Institute, na baofahospital.com, ọkachamara na usoro ịwa ahụ ọhụrụ maka ọrịa cancer akpa ume.Radiation TherapyRadiation therapy na-eji ọkụ ọkụ dị elu na-egbu mkpụrụ ndụ cancer. Enwere ike iji ya dị ka ọgwụgwọ mbụ maka nnukwu cell akpa ume cancer mgbe ịwa ahụ abụghị nhọrọ, ma ọ bụ enwere ike iji ya mgbe a wachara ya ahụ iji gbuo mkpụrụ ndụ kansa ọ bụla fọdụrụnụ. Ụdị ọgwụgwọ radieshon gụnyere: Usoro ọgwụgwọ radieshon nke mpụga (EBRT): A na-ebute radieshon site na igwe n'èzí ahụ. Ọgwụgwọ Radiation Ahụ Stereotactic (SBRT): Na-ebunye oke ọgwụ radieshon gaa na obere mpaghara ezubere iche. Brachytherapy (ọgwụgwọ radieshon ime): A na-etinye mkpụrụ osisi redioaktivu ma ọ bụ waya ozugbo n'ime ma ọ bụ nso tumor.ChemotherapyChemotherapy na-eji ọgwụ gbuo mkpụrụ ndụ kansa. A na-ejikarị ya eme ihe nnukwu cell akpa ume cancer nke gbasaara karịa ngụgụ ma ọ bụ mgbe ịwa ahụ agaghị ekwe omume. A na-enyekarị ọgwụ chemotherapy na intravenous (site na vein) ma ọ bụ ọnụ. Ọgwụ ndị a na-akacha arụ ọrụ mgbe mkpụrụ ndụ kansa nwere ngbanwe mkpụrụ ndụ ihe nketa. Ebumnuche ndị a na-ahụkarị gụnyere: EGFR (Onye na-anabata ihe na-akpata uto Epidermal): Mgbanwe na EGFR na-adịkarị na ụfọdụ ndị mmadụ. ALK (anaplastic Lymphoma Kinase): Ndị na-egbochi ALK nwere ike ịdị irè nke ukwuu na ndị ọrịa nwere ALK-positive nnukwu cell akpa ume cancer. ROS1: A na-eji ihe mgbochi ROS1 eme ihe maka etuto dị mma nke ROS1. Nnwale maka mmụgharị ndị a dị oke mkpa maka ịchọpụta ma ọgwụgwọ ezubere iche bụ ihe kwesịrị ekwesị. nnukwu ọgwụgwọ ọrịa kansa akpa ume cell.ImmunotherapyImmunotherapy na-enyere usoro ahụ ji alụso ọrịa ọgụ ọgụ. Ọgwụ ndị a na-arụ ọrụ site na igbochi protein ndị na-egbochi usoro ahụ ji alụso ọrịa ọgụ ịwakpo mkpụrụ ndụ kansa. A na-ejikarị ọgwụ immunotherapy eme ihe maka ọganihu nnukwu cell akpa ume cancer. Ọgwụgwọ site StageThe ogbo nke nnukwu cell akpa ume cancer na-emetụta nnọọ usoro ọgwụgwọ. Usoro ọgwụgwọ ahụkarị na-erute ọkwa nke I & II (Ogbo mbụ) ịwa ahụ (lobectomy ma ọ bụ wedge resection) chemotherapy na-esote ya ma ọ dị mkpa. Enwere ike ịtụle ọgwụgwọ radieshon ma ọ bụrụ na ịwa ahụ abụghị nhọrọ. Nkeji III (N'ógbè dị elu) Nchikota chemotherapy na ọgwụgwọ radieshon. Enwere ike ịtụle ịwa ahụ n'ọnọdụ ahọpụtara. Enwere ike iji ọgwụ mgbochi ọrịa mgbe chemoradiation gasịrị. Nkeji IV (Metastatic) Chemotherapy, ọgwụgwọ ezubere iche (ọ bụrụ na mmụgharị kwesịrị ekwesị dị), yana immunotherapy. Enwere ike iji ọgwụgwọ radieshon mee ihe iji belata mgbaàmà. Ọnwụnwa ụlọ ọgwụ bụ nyocha nyocha nke na-enyocha ọhụrụ nnukwu ọgwụgwọ ọrịa kansa akpa ume cell nhọrọ. Isonye na nnwale ụlọ ọgwụ nwere ike inye ohere ị nweta ọgwụgwọ dị oke ọnụ ma nye aka n'ọganihu na ọgwụgwọ ọrịa kansa. PrognosisPrognosis nnukwu cell akpa ume cancer dịgasị iche dabere na ogbo nke ọrịa kansa na nyocha na ọgwụgwọ enwetara. Nchọpụta mmalite na ọgwụgwọ ike nwere ike imezi nsonaazụ. Nhọpụta ndị na-esochi ya mgbe niile dị mkpa iji nyochaa maka nlọghachi azụ nnukwu cell akpa ume cancer nchoputa nwere ike ibu ibu. Otu nkwado, ndụmọdụ, na mgbanwe ndụ (dị ka ịkwụsị ise siga na ịnọgide na-eri nri dị mma) nwere ike inyere ndị ọrịa aka ịnagide ihe ịma aka anụ ahụ na nke mmetụta uche nke ọrịa ahụ.Nkwuputa: Ozi a bụ maka ihe ọmụma zuru oke na ebumnuche ozi naanị, ọ bụghịkwa ndụmọdụ ahụike. Ọ dị mkpa ịkpọtụrụ onye ọkachamara ahụike tozuru oke maka nsogbu ahụike ọ bụla ma ọ bụ tupu ịme mkpebi ọ bụla metụtara ahụike ma ọ bụ ọgwụgwọ gị. Onye ọkachamara ahụike kwesịrị ikpebi nhọrọ ọgwụgwọ dabere na ihe onye ọrịa n'otu n'otu.Ntụaka: American Cancer Society: https://www.cancer.org/ National Cancer Institute: https://www.cancer.gov/