ọgwụgwọ ọrịa cancer akpa ume metastatic

Ọgwụgwọ ọrịa cancer akpa ume metastatic na-elekwasị anya n'ịgbatị ndụ na ime ka ndụ dịkwuo mma mgbe ọrịa kansa gbasaara n'ofe ngụgụ. Nhọrọ ọgwụgwọ dịgasị iche dabere n'ụdị ọrịa kansa, ogbo, mmụgharị, na ahụike zuru oke. Ụzọ ndị a na-emekarị gụnyere chemotherapy, ọgwụgwọ ezubere iche, immunotherapy, ọgwụgwọ radieshon, na ịwa ahụ. Ntuziaka a na-enyocha nhọrọ ndị a n'ụzọ zuru ezu, na-enye nghọta na usoro ha, uru, na mmetụta ndị nwere ike ime. Ịghọta Ọrịa Cancer Metastatic Lung Gịnị bụ Ọrịa Cancer Metastatic Lung?Metastatic akpa ume cancer, nke a makwaara dị ka ọrịa cancer akpa ume nke IV, na-apụta mgbe mkpụrụ ndụ kansa sitere na akpụ akpa ume mbụ gbasaa n'akụkụ ahụ dị anya. Ebe a na-ahụkarị metastasis gụnyere ụbụrụ, ọkpụkpụ, imeju, na gland adrenal. Ụdị ọrịa cancer akpa ume Ụdị ọrịa cancer akpa ume abụọ bụ: Ọrịa cancer akpa ume na-abụghị nke obere cell (NSCLC): Ụdị a na-ahụkarị, gụnyere adenocarcinoma, squamous cell carcinoma, na nnukwu cell carcinoma. Ọrịa cancer akpa ume obere cell (SCLC): Ụdị ọrịa cancer akpa ume na-eto ngwa ngwa nke na-ejikọta ya na ise siga. Nchọpụta nchọpụta na StagingDiagnosis na-agụnyekarị nyocha onyonyo (CT scans, PET scans, MRI), biopsies, na ule molecular. Nhazi na-enyere aka ịchọpụta oke ọrịa cancer na-eduzi mkpebi ọgwụgwọ. Nhọrọ ọgwụgwọ maka ọrịa cancer akpa ume MetastaticEbumnuche nke ọgwụgwọ ọrịa cancer akpa ume metastatic bụ ịchịkwa uto nke ọrịa kansa, jikwaa mgbaàmà, ma melite ogo ndụ. A na-ahazikarị atụmatụ ọgwụgwọ na-adabere na ọnọdụ onye ahụ kpọmkwem.ChemotherapyChemotherapy na-eji ọgwụ gbuo mkpụrụ ndụ kansa n'ime ahụ dum. A na-ejikarị ya eme ọgwụgwọ nke mbụ metastatic akpa ume cancer. Ọgwụ chemotherapy ndị a na-emekarị gụnyere: ọgwụ ndị sitere na Platinum (cisplatin, carboplatin) Taxanes (paclitaxel, docetaxel) Pemetrexed GemcitabineChemotherapy nwere ike inwe mmetụta ndị dị ka ọgbụgbọ, ike ọgwụgwụ, ntutu isi, na ihe ize ndụ nke ibute ọrịa. Nnwale molecular dị mkpa iji chọpụta ma onye ọrịa tozuru maka ọgwụgwọ ezubere iche. Ụfọdụ ebum n'obi na ọgwụ ndị kwekọrọ na ya gụnyere: EGFR (Onye na-anabata ihe na-akpata uto Epidermal): Gefitinib, erlotinib, afatinib, osimertinib. Ọgwụ ndị a dị irè karịsịa na ndị ọrịa NSCLC nwere mmụgharị EGFR. ALK (anaplastic Lymphoma Kinase): Ndị na-emepụta ihe na-emepụta ihe ndị na-emepụta ihe na-emepụta ihe ndị na-emepụta ihe ndị na-emepụta ihe ndị na-emepụta ihe ndị na-emepụta ihe na-eme ka ndị na-emepụta ihe na-eme ka ọ bụrụ ihe na-egbuke egbuke na-egbuke egbuke na-egbuke egbuke, dịka ọmụmaatụ, lorlatinib, brigatinib, alectinib, ceritinib. Ejiri ya na ndị ọrịa NSCLC nwere nhazigharị ALK. BRAF: Dabrafenib, trametinib. Ejiri ya na ndị ọrịa NSCLC nwere mmụgharị BRAF V600E. ROS1: Crizotinib, entrectinib. Ejiri ya na ndị ọrịa NSCLC nwere ROS1 fusions. NTRK: Larotrectinib, entrectinib. Ejiri ya na ndị ọrịa NSCLC nwere njikọ NTRK. MET: Capmatinib, tepotinib. Ejiri ya na ndị ọrịa NSCLC nwere MET exon 14 na-awụgharị mmụgharị. RET: Selpercatinib, pralsetinib. A na-eji ya na ndị ọrịa NSCLC nwere RET fusions. Usoro ọgwụgwọ a na-atụ anya na-enwekarị mmetụta dị ole na ole karịa chemotherapy, mana ha na-adị irè ma ọ bụrụ na ọrịa kansa nwere ebumnuche a kapịrị ọnụ. Ndị na-egbochi ihe mgbochi mgbochi bụ ụdị immunotherapy a na-ejikarị na ya ọgwụgwọ ọrịa cancer akpa ume metastatic. Ihe atụ gụnyere: Pembrolizumab (Keytruda) Nivolumab (Opdivo) Atezolizumab (Tecentriq) Durvalumab (Imfinzi) Ipilimumab (Yervoy) Ọgwụ ndị a na-egbochi protein ndị na-egbochi usoro ahụ ji alụso ọrịa ọgụ site n'ịwakpo mkpụrụ ndụ cancer, na-ekwe ka usoro ahụ ji alụso ọrịa ọgụ nwee nzaghachi siri ike. Mmetụta nwere ike ịgụnye ike ọgwụgwụ, ọkụ ọkụ, afọ ọsịsa, na mbufụt nke akụkụ ahụ dị iche iche.Radiation TherapyRadiation therapy na-eji ọkụ ọkụ dị elu gbuo mkpụrụ ndụ cancer. Enwere ike iji ya belata etuto ahụ, belata ihe mgbu, ma ọ bụ gwọọ metastases na mpaghara ụfọdụ dị ka ụbụrụ ma ọ bụ ọkpụkpụ. Ụdị ọgwụgwọ radieshon na-agụnye: Mpụga beam radiation ọgwụgwọ Stereotactic body radiation therapy (SBRT) Stereotactic radiosurgery (SRS) Mmetụta na-adabere na ọnọdụ na dose nke radieshon.Ịwa ahụ n'ozuzu abụghị ọgwụgwọ bụ isi maka ya. metastatic akpa ume cancer, mana enwere ike ịtụle ya n'ọnọdụ ụfọdụ, dị ka iwepu metastasis nke naanị ya ma ọ bụ iji belata mgbaàmà. Dịka ọmụmaatụ, ndị Shandong Baofa Cancer Research Institute mgbe ụfọdụ na-eji usoro ịwa ahụ na-akpa ike dị ntakịrị iji lebara saịtị metastatic anya kpọmkwem. Ọnwụnwa ụlọ ọgwụ bụ nyocha nyocha nke na-enyocha ọgwụgwọ ọhụrụ ma ọ bụ ngwakọta nke ọgwụgwọ. Ndị ọrịa nwere metastatic akpa ume cancer nwere ike ịtụle isonye na ule ụlọ ọgwụ iji nweta ọgwụgwọ ndị na-egbu egbu. Ijikwa akara ngosi na mmetụta dị n'akụkụ ijikwa mgbaàmà na mmetụta ndị dị n'akụkụ bụ akụkụ dị mkpa nke ọgwụgwọ ọrịa cancer akpa ume metastatic. Nke a nwere ike ịgụnye: Nlekọta mgbu Nkwado nri nri Nlekọta nke ọgbụgbọ na ọgbụgbọ iku ume nkwadoPrognosis na Ịlanahụ ỌnụegoAmụma maka metastatic akpa ume cancer dịgasị iche dabere n'ọtụtụ ihe, gụnyere ụdị ọrịa kansa akpa ume, oke mgbasa, ahụike zuru oke nke onye ọrịa, yana nzaghachi ọgwụgwọ. Ọganihu ndị e mere n'oge na-adịbeghị anya na ọgwụgwọ ezubere iche na immunotherapy emewo ka ọnụ ọgụgụ nlanarị dị mma maka ụfọdụ ndị ọrịa. Dị ka American Cancer Society si kwuo, afọ 5 na-adị ndụ maka ọrịa cancer akpa ume metastatic bụ ihe dịka 7% (maka ọkwa niile nke ọrịa cancer akpa ume jikọtara, ọnụ ọgụgụ ahụ bụ 25%). [1] Nke a na-egosipụta mkpa nyocha na-aga n'ihu na mmepe nke ọgwụgwọ ọhụrụ. Nke a bụ ntụle dị mfe nke nhọrọ ọgwụgwọ, nzube ha, na mmetụta ndị nwere ike ime: Ọgwụgwọ Nzube Mmetụta Mmetụta Chemotherapy na-egbu mkpụrụ ndụ cancer n'ime ahụ niile Ọgbụgbọ, ike ọgwụgwụ, ntutu isi, ọrịa Ezubere ọgwụgwọ Block kpọmkwem ụmụ irighiri ihe na-etinye aka na ọrịa cancer na-adabere na ọgwụ ahụ; nwere ike ịgụnye ọkụ ọkụ anụ ahụ, afọ ọsịsa, nsogbu imeju Immunotherapy Nyere usoro ahụ ji alụso ọrịa ọgụ ọgụ mkpụrụ ndụ kansa ike ike ọgwụgwụ, ọkụ ọkụ, afọ ọsịsa, mbufụt nke akụkụ ahụ Radiation Therapy Gbuo mkpụrụ ndụ kansa n'otu ebe ike ọgwụgwụ, mgbanwe akpụkpọ ahụ, mmebi akụkụ ahụ dị nso ebe ọgwụgwọ ịwa ahụ Wepu metastases ma ọ bụ wepụ ihe mgbaàmà mgbu, ọrịa, ọbara ọgbụgba mmechi.Ọgwụgwọ ọrịa cancer akpa ume metastatic bụ ogige dị mgbagwoju anya ma na-agbanwe agbanwe. Ọganihu na ọgwụgwọ ezubere iche na immunotherapy emewo ka nsonaazụ dị mma maka ụfọdụ ndị ọrịa. Ọ dị mkpa maka ndị ọrịa ka ha na ndị otu ahụike ha rụkọọ ọrụ iji mepụta atụmatụ ọgwụgwọ ahaziri onwe nke na-egbo mkpa na ebumnuche ha kpọmkwem. Na-akpọtụrụ onye ọkachamara ahụike ruru eru mgbe niile maka nyocha na ọgwụgwọ nke ọnọdụ ahụike ọ bụla. Ntụle[1] American Cancer Society. (n.d.). Ọnụego ịlanarị ọrịa kansa akpa ume. Ewepụtara na https://www.cancer.org/cancer/lung-cancer/detection-diagnosis-staging/survival-rates.html