Ubushinwa impyiko kanseri ya kanseri yerekana indwara

Ubushinwa Impyiko Zifata Indwara ya Carcinoma Yerekana Ubusobanuro bwa Pathologiya ya Carcinoma Yimpyiko Y’UbushinwaIyi ngingo itanga incamake yuzuye yibiranga indwara ya kanseri yimpyiko (RCC) mubushinwa, yibanda kubisobanuro rusange, uburyo bwo kwisuzumisha, nibisobanuro byerekana. Tuzasesengura ubushakashatsi buheruka gukorwa nubuyobozi bwo kwa muganga kugirango dusobanukirwe neza iyi kanseri yiganje. Aya masoko agenewe inzobere mu buzima n’abashakashatsi bashishikajwe n’indwara ya RCC.

Icyorezo cya Epidemiologiya n'ingaruka za RCC mu Bushinwa

Kanseri y'impyiko yerekana ikibazo gikomeye cyubuzima rusange mubushinwa. Mugihe ibipimo nyabyo byanduye bitandukana mukarere, ubushakashatsi bwerekana ko izamuka ryiyongera, ryerekana imiterere yisi. Impamvu nyinshi ziterwa ningaruka zigira uruhare mu iterambere rya RCC, harimo kunywa itabi, umubyibuho ukabije, hypertension, n'amateka y'umuryango. Byongeye kandi, guhura nuburozi bwibidukikije bushobora kugira uruhare. Gusobanukirwa nibi byago ni ngombwa mugushira mubikorwa ingamba zo gukumira.

Ibyiciro bya Pathologiya ya RCC

Ubwoko bwamateka bwiganje bwa Ubushinwa kanseri yimpyiko ni selile RCC (ccRCC), ibara umubare munini wimanza. Ariko, ubundi bwoko butandukanye, nka papillary RCC, chromophobe RCC, hamwe no gukusanya umuyoboro RCC, nabyo bibaho. Ibyiciro bya patologi byukuri nibyingenzi kuyobora ibyemezo byo kuvura no guhanura ibizaba. Ubuhanga bugezweho bwa pathologiya, harimo na immunohistochemie na profekile ya molekulari, burakoreshwa cyane kugirango tunonosore neza.

Kuraho kanseri yimpyiko ya kanseri (ccRCC)

ccRCC irangwa na cytoplazme isobanutse muri selile yibibyimba bitewe na glycogene nyinshi hamwe na lipide. Bikunze kwerekana icyitegererezo cyibyari bikomeye na tubules. Guhindura molekuline yihariye, nka VHL ihindagurika rya gene, bikunze guhuzwa na ccRCC. Gusobanukirwa ibi biranga molekuline ningirakamaro mugutezimbere imiti igamije.

Ubundi bwoko bwa RCC

Papillary RCC irangwa nuburyo busa na papilae, akenshi bugaragaza prognoza nziza kuruta ccRCC. Chromophobe RCC ntisanzwe kandi irerekana eosinofilique cytoplazme. Gukusanya umuyoboro RCC ni ubwoko budasanzwe kandi bukabije. Itandukaniro nyaryo muri ubu buryo ni ngombwa mu ngamba zihariye zo kuvura.

Uburyo bwo Gusuzuma RCC mu Bushinwa

Gusuzuma Ubushinwa kanseri yimpyiko mubisanzwe bikubiyemo guhuza amashusho (CT, MRI) hamwe no gusuzuma histopathologique ya biopsy cyangwa kubagwa. Iterambere mubuhanga bwo gufata amashusho, harimo na CT nyinshi, byongera kumenya no kuranga impyiko. Biopsy nziza-inshinge nziza irashobora gutanga amakuru yambere ya cytologiya, mugihe kubaga kubaga bituma hasuzumwa neza indwara.

Ibintu byamenyekanye hamwe nuburyo bwo kuvura

Ibintu byinshi bigira ingaruka kumenyekanisha rya RCC, harimo ikibyimba (stade ya TNM), icyiciro cyamateka, no kuba metastasis. Sisitemu yo kubika TNM itanga uburyo busanzwe bwo gutandukanya ibyago. Byongeye kandi, sisitemu yo gutanga amanota ya Fuhrman isuzuma ibiranga ingufu za kirimbuzi za selile RCC kugirango zihanure imyitwarire ikaze. Izi ngingo ziyobora ibyemezo byo kuvura, uhereye kubagwa kubagwa kugeza kubuvuzi bugenewe no gukingira indwara.

Ubushakashatsi nicyerekezo kizaza

Ubushakashatsi burimo gukorwa mu Bushinwa bwibanze ku kunoza gutahura hakiri kare, kunonosora uburyo bwo gusuzuma, no guteza imbere imiti mishya Ubushinwa kanseri yimpyiko. Ibi birimo iperereza kuri biomarkers kugirango hamenyekane hakiri kare, ubushakashatsi ku ntego zo kuvura udushya, hamwe n’amavuriro asuzuma uburyo bwo kuvura udushya. Ubufatanye hagati y'abashakashatsi, abaganga, n'abafata ibyemezo ni ngombwa kugira ngo bateze imbere imyumvire n'imicungire ya RCC mu Bushinwa.

Imbonerahamwe: Kugereranya Ubwoko bwa RCC

Inshingano: Aya makuru agamije uburezi gusa kandi ntagomba gufatwa nkinama zubuvuzi. Buri gihe ujye ubaza inzobere mu buzima kubibazo byose byubuzima cyangwa mbere yo gufata ibyemezo byose bijyanye nubuzima bwawe cyangwa kwivuza.

Ukeneye ibisobanuro birambuye kubyerekeye ubushakashatsi bwa kanseri no kuvura, nyamuneka sura Shandong Baofa Ikigo Cyubushakashatsi Kanseri.