kanseri yimpyiko kanseri

Kanseri y'impyiko metastatike (mRCC) ni ubwoko bwa kanseri y'impyiko yakwirakwiriye mu bindi bice by'umubiri. Uburyo bwo kuvura buratandukanye bitewe nicyiciro nibiranga kanseri, ariko akenshi harimo kuvura intego, immunotherapie, kubaga, hamwe no kuvura imirasire. Kumenya hakiri kare hamwe nuburyo bushya bwo kuvura nibyingenzi mugutezimbere ibisubizo kubarwayi barwaye mRCC. Aka gatabo gatanga incamake yimbitse ya mRCC, ikubiyemo ibitera, ibimenyetso, kwisuzumisha, uburyo bwo kuvura, hamwe no guhanura.Ni ubuhe bwoko bwa kanseri yo mu bwoko bwa Carcinoma na Metastasis? Bikomoka kumurongo wa tubulike yegeranye, utuntu duto cyane mumpyiko zungurura amaraso kandi zikuraho imyanda. Iyo RCC yipimishije, bivuze ko kanseri ya kanseri yavuye mu kibyimba cyambere cyo mu mpyiko ikwirakwira mu bindi bice by'umubiri, nk'ibihaha, amagufwa, ubwonko, cyangwa umwijima. Iyo imaze gukwirakwira, ishyirwa mu rwego rwa kanseri yimpyiko kanseri . Umubyibuho ukabije: Kugira umubyibuho ukabije cyangwa umubyibuho ukabije bifitanye isano no kwiyongera. Umuvuduko ukabije wamaraso: Umuvuduko ukabije wamaraso urashobora kwangiza impyiko no kongera kanseri. Amateka yumuryango: Kugira amateka yumuryango wa RCC byongera ibyago byawe. Indwara zimwe na zimwe twarazwe, nk'indwara ya von Hippel-Lindau (VHL), syndrome ya Birt-Hogg-Dube, hamwe na kanseri yo mu bwoko bwa papillary renal selile kanseri ifitanye isano n'ingaruka nyinshi. Indwara Yimpyiko Yambere cyangwa Dialysis: Abantu barwaye impyiko zidakira, cyane cyane abafite dialyse, bafite ibyago byinshi. Guhura na Shimi zimwe na zimwe: Guhura nakazi ka kadmium, trichlorethylene, hamwe nudukoko twangiza ibyatsi byatewe na RCC.Ibimenyetso bya kanseri yimpyiko ya kanseri ya kanseri ya mbere ya RCC akenshi nta bimenyetso ifite. Mugihe ikibyimba gikura cyangwa metastasize, ibimenyetso bishobora kugaragara. Ibi birashobora gutandukana bitewe na kanseri yakwirakwiriye, ariko ibimenyetso bisanzwe bya kanseri yimpyiko kanseri ushizemo: Amaraso mu nkari (hematuria) Ububabare budashira kuruhande cyangwa inyuma Igibyimba cyangwa misa kuruhande cyangwa inyuma Kugabanya ibiro bidasobanutse Umunaniro ukabije udatewe no kwandura Anemia (kubara amaraso make atukura) Kubabara amagufwa (niba kanseri yarakwirakwiriye kumagufa) Kubyimba mumaguru no mumaguruIsuzuma rya Metastatic Renal Cell CarcinomaDi kanseri yimpyiko kanseri mubisanzwe birimo guhuza ibizamini byumubiri, ibizamini byerekana amashusho, na biopsies. Ikizamini cyumubiri: Muganga azakora ikizamini cyumubiri kugirango arebe niba bidasanzwe. Ibizamini byo Kwerekana: CT Gusikana: CT scan itanga amashusho arambuye yimpyiko nuduce tuyikikije kandi birashobora gufasha kumenya ibibyimba no gusuzuma ubunini bwaho n'aho biherereye. MRI: MRI irashobora gutanga amashusho arambuye kandi ikoreshwa mugusuzuma urugero rwa kanseri. Gusikana amagufwa: Gusuzuma amagufwa bikoreshwa mu gusuzuma niba kanseri yarakwirakwiriye mu magufa. PET Scan: Gusuzuma PET birashobora gufasha kumenya kanseri ya kanseri mumubiri. Biopsy: Biopsy ikubiyemo gukuramo ingero ntoya yimpyiko cyangwa ahantu metastatike kugirango isuzumwe kuri microscope. Ibi byemeza isuzuma rya RCC kandi bifasha kumenya ubwoko bwihariye bwa RCC.Ihitamo ryuburyo bwo kuvura kanseri yimpyiko ya kanseri ya kanseri ya kanseri yimpyiko kanseri biterwa nibintu byinshi, harimo urugero rwa kanseri, ubuzima bwumurwayi muri rusange, nibiranga ikibyimba. Uburyo rusange bwo kuvura burimo: Ubuvuzi bugamije Imiti igamije kuvura yibanda kuri molekile zihariye zigira uruhare mu mikurire ya kanseri no kubaho. Iyi miti irashobora gufasha gutinda gukura kwa kanseri no kuzamura imibereho. Ubuvuzi bukunze kugaragara kuri mRCC burimo: Inhibitor za VEGF (urugero: sunitinib, sorafenib, pazopanib, axitinib, cabozantinib): Iyi miti ihagarika inzira yo gukura kw'imitsi iva mu mitsi (VEGF), ifite akamaro kanini mu mitsi y'amaraso mu bibyimba. Inhibitori ya mTOR (urugero, everolimus, temsirolimus): Iyi miti ihagarika intego y’inyamabere y’inzira ya rapamycin (mTOR), igira uruhare mu mikurire y’utugingo ngengabuzima na metabolism. Iyi miti yerekanye ibisubizo bitanga umusaruro mukuvura mRCC. Ubudahangarwa busanzwe bwa mRCC burimo: Inzitizi za Checkpoint (urugero, nivolumab, pembrolizumab, ipilimumab): Iyi miti ibuza poroteyine ku ngirabuzimafatizo z'umubiri zibabuza kwibasira kanseri ya kanseri. Ibi birashobora kugabanya ibimenyetso no kuzamura imibereho. Cytoreductive nephrectomy ikubiyemo gukuramo ikibyimba cyibanze cyimpyiko nubwo kanseri yakwirakwiriye mubindi bice byumubiri. Ibi birashobora kunoza imikorere yizindi miti.Ubuvuzi bwa RadiyoyasiRadiation ivura ikoresha imirasire yingufu nyinshi kugirango yice selile. Irashobora gukoreshwa mu kugabanya ububabare cyangwa ibindi bimenyetso biterwa n'ibibyimba metastatike, cyane cyane mu magufa cyangwa mu bwonko. Ikigeragezo cya Clinical Ibigeragezo bya kliniki ni ubushakashatsi bwakozwe busuzuma uburyo bushya bwo kuvura kanseri. Abarwayi hamwe kanseri yimpyiko kanseri irashobora gutekereza kwitabira igeragezwa rya clinique kugirango igere ku buvuzi bugezweho. Kumenyekanisha kanseri yimpyiko yimpyiko CarcinomaIbisobanuro kuri kanseri yimpyiko kanseri biratandukanye bitewe nibintu byinshi, harimo urugero rwa kanseri, ubuzima bwumurwayi muri rusange, nigisubizo cyo kwivuza. Mu mateka, mRCC yari ifite imenyekanisha ribi, ariko iterambere mu buvuzi bugamije no gukingira indwara ryateje imbere cyane abarwayi benshi. Ibintu bishobora kugira ingaruka ku bimenyekanisha harimo amanota mpuzamahanga y’imyororokere ya Carcinoma Database Consortium (IMDC) amanota y’ibyago, atekereza ku bihe nkigihe cyo kwisuzumisha kugeza kwivuza, imiterere yimikorere, urugero rwa hemoglobine, urugero rwa calcium, kubara neutrophil, no kubara kwa platine. Kubana na Metastatic Renal Cell CarcinomaKubaho hamwe kanseri yimpyiko kanseri birashobora kuba ingorabahizi, haba kumubiri no mumarangamutima. Ni ngombwa kugira sisitemu ikomeye yo gushyigikira no gufata ingamba zo gucunga ibimenyetso n'ingaruka zo kuvurwa. Ibi birashobora kubamo: Gucunga ububabare Inkunga yintungamubiri Imyitozo ngororamubiri nubuvuzi bwumubiri Impanuro cyangwa amatsinda atera inkunga Uruhare rwubushakashatsi bwa kanseri ya Shandong BaofaAt Shandong Baofa Ikigo Cyubushakashatsi Kanseri, twiyemeje gutanga ubuvuzi bwuzuye kandi bushya bwa kanseri. Twiyemeje guteza imbere ubushakashatsi bwa kanseri no guha abarwayi imiti myiza ishoboka. Itsinda ryacu ryinzobere muri oncologiste, kubaga, hamwe nabakozi bunganira bafatanyiriza hamwe gutegura gahunda yo kuvura yihariye kuri buri murwayi yibanda ku kuzamura imibereho no kubaho muri rusange. Twihatira gutanga iterambere rigezweho mu kuvura kanseri, harimo kuvura indwara, immunotherapie, hamwe n’ibizamini byo kwa muganga. Icyerekezo kizaza muri Metastatic Renal Cell Carcinoma UbushakashatsiUbushakashatsi muri kanseri yimpyiko kanseri irakomeje, ifite intego yo guteza imbere uburyo bushya kandi bunoze bwo kuvura. Ibice byubushakashatsi bigezweho birimo: Gutezimbere uburyo bushya bwo kuvura no gukingira indwara Kumenya ibimenyetso bya biomark bishobora guhanura ibisubizo byubuvuzi Gusobanukirwa uburyo bwo kurwanya imiti igamije kuvura no gukingira indwara Gutegura ingamba nshya zo gukumira ikwirakwizwa rya RCCBy dukomeje guteza imbere imyumvire yacu kuri mRCC, dushobora kunoza ibisubizo ku barwayi bafite iyi ndwara itoroshye.