rcc impyiko kanseri yimpyiko

RCC (Carcinoma Cell) ni ubwoko bwa kanseri y'impyiko ku bantu bakuru. Iyi ngingo irasesengura indwara, ikubiyemo ubwoko bwayo, ibimenyetso, gusuzuma, uburyo bwo kuvura, hamwe no guhanura. Niki Kanseri y'impyiko?Indwara ya kanseri yimpyiko (RCC), cyangwa kanseri y'impyiko, ikomoka kumurongo wa tubule yegeranye cyane, igice cyigituba gito cyane mumpyiko cyungurura amaraso kandi kigakuraho imyanda. Gusobanukirwa ubwoko butandukanye nibyiciro bya RCC ni ngombwa mu kuvura neza. Ubwoko bwa Kanseri y'impyikoUbwoko butandukanye bwa RCC kubaho, buri kimwe gifite imiterere itandukanye hamwe nuburyo bwo kuvura. Ubwoko bukunze kuboneka harimo: Sobanura Akagari Kanseri y'impyikoUbwoko bwiganje cyane, bingana na 70% ya RCC manza. Irangwa na selile igaragara neza cyangwa yera munsi ya microscope kubera ibintu byinshi bya lipide. Inkomoko: Sosiyete y'AbanyamerikaPapillary Kanseri y'impyikoUbwoko bwa kabiri bukunze kugaragara, bugizwe na 10-15% byimanza. Papillary RCC irangwa nintoki zisa na projection bita papillae. Bikunze kuba bifitanye isano na genetique runaka. Hariho ubwoko bubiri bwingenzi: Ubwoko bwa 1 nubwoko bwa 2, hamwe nubwoko bwa 2 muri rusange bukaze. Chromophobe Kanseri y'impyikoUbu bwoko bwerekana hafi 5% ya RCC manza. Chromophobe RCC mubisanzwe bifite prognoza nziza ugereranije na selile isobanutse RCC. Ingirabuzimafatizo nini kandi nziza kuruta selile isobanutse RCC selile. Gukusanya Umuyoboro Kanseri y'impyikoUbwoko budasanzwe kandi bukaze, bingana na 1% byimanza. Gukusanya umuyoboro RCC ikomoka mu miyoboro yo gukusanya impyiko, itwara inkari mu ruhago. Bikunze gusuzumwa mugihe cyanyuma kandi birashobora kugorana kuvura.Ubuvuzi Kanseri y'impyikoUbundi bwoko budasanzwe kandi bukaze, cyane cyane bugira ingaruka kubantu bafite ingirabuzimafatizo. Medullary RCC ikunze guhuzwa nibisubizo bibi.Ibimenyetso bya Kanseri y'impyikoIntambwe yambere ya RCC ntishobora kwerekana ibimenyetso bigaragara. Ariko, uko ikibyimba gikura, ibimenyetso bishobora kubamo: Amaraso mu nkari (hematuria) Ububabare buhoraho muruhande cyangwa umugongo Ikibyimba cyangwa misa kuruhande cyangwa inyuma Kugabanuka ibiro bidasobanutse Gutakaza ubushake bwumunaniro Umunaniro udaterwa no kwandura Anemia (kubara amaraso make yumutuku) Niba uhuye nibimenyetso bimwe na bimwe, ni ngombwa kubaza umuganga kugirango asuzume neza.Diagnose Kanseri y'impyikoGusuzuma RCC mubisanzwe bikubiyemo guhuza ibizamini byumubiri, ibizamini byerekana amashusho, hamwe na biopsy.Ibizamini byo KwerekanaIshusho yerekana amashusho bigira uruhare runini mugushakisha no gutunganya RCC. Ibizamini bisanzwe byerekana amashusho birimo: Kubara Tomografiya (CT) scan: Itanga ibisobanuro birambuye byambukiranya impyiko hamwe nuduce twose. Magnetic Resonance Imaging (MRI): Tanga itandukaniro ryiza ryoroshye kandi rifite akamaro kanini mugusuzuma urugero rwibibyimba no kumenya gukwirakwira mubikorwa byegeranye. Ultrasound: Irashobora gufasha gutandukanya imbaga nini na cysts yuzuye amazi mumpyiko. Impyiko Arteriografiya (Angiography): Isuzuma rya X-ray yimitsi yimpyiko nyuma yo guterwa irangi. Ikoreshwa cyane kurenza CT cyangwa MRI.BiopsyA biopsy ikubiyemo gukuramo urugero ruto rwimpyiko kugirango rusuzumwe kuri microscope. Biopsy irakenewe kugirango hemezwe isuzuma rya RCC hanyuma umenye ubwoko bwubwoko. Ishusho ya biopsies ikorwa mubisanzwe ikoresheje CT cyangwa ultrasound kugirango harebwe neza intego yibice bikekwa. Icyiciro cya Kanseri y'impyikoIcyiciro cya RCC bivuga urugero rwa kanseri kandi niba yarakwirakwiriye mu bindi bice by'umubiri. Gutegura ni ngombwa mu kumenya uburyo bukwiye bwo kuvura no guhanura ibizaba. Sisitemu yo kubika TNM (Tumor, Node, Metastasis) ikoreshwa cyane: T (Tumor): Sobanura ingano nubunini bwikibyimba cyibanze. N (Node): Yerekana niba kanseri yarakwirakwiriye hafi ya lymph node. M (Metastasis): Yerekana niba kanseri yarakwirakwiriye ahantu kure, nk'ibihaha, amagufwa, cyangwa ubwonko.Icyiciro kiva kuri I kugeza ku cya IV, Icyiciro cya I kikaba icyiciro cya mbere naho Icyiciro cya IV kikaba cyateye imbere cyane. Amahitamo yo kuvura Kanseri y'impyikoUmuti wa RCC Biterwa nibintu byinshi, harimo icyiciro cya kanseri, ubuzima bwumurwayi muri rusange, hamwe nibyo akunda. Uburyo rusange bwo kuvura burimo: Kubaga Gukuraho ikibyimba akenshi niwo muti wibanze waho RCC (Icyiciro I-III). Amahitamo yo kubaga arimo: Nephrectomy igice: Kurandura ikibyimba gusa nuduce duto twa tissue nzima. Ubu buryo burahitamo mugihe bishoboka kugirango ubungabunge imikorere yimpyiko. Nephrectomy: Gukuraho impyiko zose, hamwe nuduce dukikije, nka glande ya adrenal na lymph node. Ibi mubisanzwe bikorwa kubyimba binini cyangwa mugihe igice cya nephrectomie kidashoboka. Ubuvuzi bugamije Ubuvuzi bugamije kuvura ni imiti yibasira molekile zigira uruhare mu mikurire ya kanseri no kubaho. Iyi miti irashobora kuba ingirakamaro mu kuvura iterambere RCC (Icyiciro cya IV) kandi birashobora no gukoreshwa mubyiciro byambere mubihe bimwe. Ingero zirimo: Inzitizi za VEGF: Sunitinib (Sutent), Sorafenib (Nexavar), Pazopanib (Votrient), Axitinib (Inlyta), Bevacizumab (Avastin) Inhibitor ya mTOR: Temsirolimus (Torisel), Everolimus (Afinitor) ImmunotherapyImmunotherapy imiti ifasha umubiri wumubiri kumenya no gutera kanseri. Immunotherapy yerekanye amasezerano akomeye mukuvura iterambere RCC. Ingero zirimo: Inhibitori ya PD-1: Nivolumab (Opdivo), Pembrolizumab (Keytruda) Inzitizi za CTLA-4: Ipilimumab (Yervoy) Gukingira Immunotherapy: Nivolumab wongeyeho IpilimumabUbundi buvuzi Ubundi buvuzi bushobora gukoreshwa mubihe bimwe na bimwe, nka: Ubuvuzi bw'imirasire: Gukoresha imirasire yingufu nyinshi kugirango wice selile. Ntabwo isanzwe ikoreshwa kuri RCC, ariko irashobora gukoreshwa mukuvura metastase yamagufa cyangwa kugabanya ububabare. Ubuvuzi bwo gukuraho: Ubuhanga nka radiofrequency ablation (RFA) cyangwa cryoablation ikoresha ubushyuhe cyangwa imbeho kugirango isenye ikibyimba. Ibi birashobora gukoreshwa kubibyimba bito kubarwayi badakandida beza kubagwa. Igenzura rifatika: Kubibyimba bito cyane, bikura buhoro buhoro, gukurikiranira hafi (gukurikiranira hafi) birashobora kuba amahitamo aho kuvurwa byihuse.Prognose ya Kanseri y'impyikoKumenyekanisha kwa RCC biratandukanye bitewe nibintu byinshi, harimo icyiciro cya kanseri, subtype, nubuzima bwumurwayi muri rusange. Kumenya hakiri kare no kuvura nibyingenzi mugutezimbere ibisubizo. Ukurikije Uwiteka Gahunda y'igihugu ya Kanseri ya SEER, imyaka 5 ugereranije yo kubaho kurugero rwaho RCC (kanseri itakwirakwiriye hanze y'impyiko) ni ndende. Nyamara, igipimo cyo kubaho kigabanuka cyane mubyiciro byindwara. Igipimo cyimyaka 5 yo Kurokoka Kurwara Kanseri Yimpyiko Yicyiciro Cyimyaka 5 Igipimo cyo Kurokoka Cyimyaka 5 Yegereye 93% Uturere 71% Intera 15% Ibyiciro BYABONA Byahujwe 76% Iyi mibare ishingiye kubantu basuzumwe RCC imyaka myinshi ishize, bityo igipimo cyo kubaho gishobora kuba kinini ubu kubera iterambere mubuvuzi.Kubushishozi bwinzobere nuburyo bwo kuvura buhanitse Kanseri y'impyiko, shakisha ingamba zubushakashatsi kuri Shandong Baofa Ikigo Cyubushakashatsi Kanseri, yitangiye guteza imbere ubuvuzi bwa kanseri.