rcc

RCC, cyangwa kanseri y'impyiko Carcinoma, ni ubwoko bwa kanseri y'impyiko ku bantu bakuru. Bitangirira kumurongo wuduce duto mumpyiko. Ibimenyetso birashobora kuba byoroshye, ariko kwisuzumisha hakiri kare no kuvura bizamura cyane ibisubizo. Aka gatabo karasobanura neza impamvu, ibimenyetso, gusuzuma, uburyo bwo kuvura, hamwe na prognoz ya RCC.Kanseri y'impyiko (RCC) ni iki? Kanseri y'impyiko (RCC) ni ubwoko bwa kanseri ikomoka mu mpyiko. Impyiko ni ingingo zimeze nk'ibishyimbo, buri kimwe kijyanye n'ubunini bw'igituba cyawe, giherereye inyuma yingingo zawe, imwe kuruhande rwumugongo. Zungurura imyanda n'amazi arenze mumaraso yawe, hanyuma bigasohoka muminkari yawe. RCC ikora iyo selile nzima mumpyiko imwe cyangwa zombi zihindutse zigakura ntizigenzure, zikora misa. Iyi misa irashobora kuba nziza (idafite kanseri) cyangwa mbi (kanseri). Kanseri nyinshi zimpyiko ni RCC.Ubwoko bwa Carcinoma Yimpyiko Hariho ubwoko bwinshi bwa RCC, buri kimwe gifite ibimenyetso bitandukanye nibiteganijwe. Ubwoko bukunze kuboneka harimo: Sobanura Akagari RCC: Ubu ni ubwoko bwiganje cyane, bingana na 70-80% ya RCC manza. Irangwa na selile zisobanutse cyangwa zisa neza iyo urebye munsi ya microscope. Papillary RCC: Ubwoko bwa kabiri bukunze kuboneka, bingana na 10-15% byimanza. Papillary RCC ifite urutoki rumeze (papillae). Chromophobe RCC: Ubu bwoko bwerekana hafi 5% ya RCC manza. Mubisanzwe bifite prognoza nziza kuruta selile isobanutse RCC. Gukusanya Umuyoboro RCC: Ubwoko budasanzwe kandi bukaze bwa RCC, ibarirwa munsi ya 1% yimanza. RCC idafite ibyiciro: Rimwe na rimwe, ingirangingo za kanseri ntizihuza neza na kimwe mu byiciro byavuzwe haruguru. Ibintu bishobora gutera RCCIbintu byinshi bishobora kongera ibyago byo kwandura RCC. Muri byo harimo: Kunywa itabi: Kunywa itabi ni ikintu gikomeye gishobora guteza ibyago, hafi kwikuba kabiri ibyago byo RCC. Umubyibuho ukabije: Ibiro birenze urugero byongera ibyago byo RCCcyane cyane mu bagore. Umuvuduko ukabije w'amaraso: Umuvuduko ukabije w'amaraso ujyana no kwiyongera. Amateka yumuryango: Kugira amateka yumuryango wa kanseri yimpyiko byongera ibyago byawe. Indwara zimwe na zimwe zarazwe, nk'indwara ya von Hippel-Lindau (VHL), syndrome ya Birt-Hogg-Dube, hamwe na kanseri yo mu bwoko bwa papillary impyiko kanseri, byongera ibyago cyane. Indwara Yimpyiko Yambere cyangwa Dialysis: Abantu barwaye impyiko zidakira, cyane cyane abafite dialyse, bafite ibyago byinshi. Imiti imwe n'imwe: Gukoresha igihe kirekire kugabanya ububabare bumwe na bumwe, nka phenacetine, bifitanye isano no kongera ibyago (phenacetine ntigikoreshwa cyane). Guhura nibintu bimwe na bimwe: Guhura na kadmium hamwe na bimwe mubyatsi byica bifitanye isano no kwiyongera kwibyago.Ibimenyetso bya RCCMu ntangiriro, RCC ntishobora gutera ibimenyetso bigaragara. Mugihe ikibyimba gikura, ibimenyetso bishobora gukura, harimo: Amaraso mu nkari (Hematuria): Iki ni kimwe mu bimenyetso bikunze kugaragara. Ububabare bwo hepfo: Kubabara kuruhande rumwe rwumugongo wo hasi, ntabwo bifitanye isano no gukomeretsa. Ikibyimba cyangwa Misa kuruhande cyangwa inyuma: Imbaga ishoboka mu nda cyangwa mu mpande. Gutakaza ibiro: Kugabanuka kudasobanutse. Umunaniro: Umunaniro uhoraho kandi udasobanutse. Umuriro: Umuriro udatewe no kwandura. Anemia: Umubare muto wamaraso atukura.Gusuzuma RCCNiba umuganga wawe akeka RCC, birashoboka ko bazakora ibizamini byinshi kugirango bemeze ko basuzumye kandi bamenye urugero rwa kanseri. Ibi bizamini birashobora kubamo: Ikizamini cyumubiri: Muganga azagusuzuma akubaze amateka yubuvuzi nibimenyetso byawe. Ibizamini by'inkari: Kwipimisha inkari birashobora kumenya amaraso mu nkari nibindi bidasanzwe. Kwipimisha Amaraso: Kwipimisha amaraso birashobora gusuzuma imikorere yimpyiko no gushakisha ibimenyetso bya kanseri. Ibizamini byo Kwerekana: Kubara Tomografiya (CT) Gusikana: CT scan itanga amashusho arambuye yimpyiko nuduce dukikije. Nibizamini bisanzwe byerekana amashusho bikoreshwa mugupima RCC. Magnetic Resonance Imaging (MRI): MRI ikoresha imirima ya magneti hamwe na radio yumurongo kugirango ikore amashusho arambuye. Irashobora gukoreshwa mugusuzuma neza ibibyimba bigaragara kuri CT scan. Ultrasound: Ultrasound ikoresha amajwi kugirango ikore amashusho. Irashobora gukoreshwa mugutandukanya ibibyimba bikomeye na cysts yuzuye amazi. Impyiko Arteriogram: Arteriogram ikoresha irangi ryatewe mumitsi yimpyiko kugirango yerekane amaraso atembera mumpyiko. Biopsy: Biopsy ikubiyemo gukuramo urugero ruto rw'uturemangingo two mu kibyimba cy'impyiko kugira ngo dusuzume kuri microscope. Ntabwo buri gihe ari ngombwa, ariko birashobora gufasha mukwemeza kwisuzumisha no kumenya ubwoko bwubwoko bwa RCC.Gutegura RCCOnce RCC isuzumwa, kanseri ikorwa kugirango hamenyekane urugero rwindwara. Gutegura bifasha abaganga gutegura uburyo bwiza bwo kuvura. Sisitemu yo kubika TNM (Tumor, Node, Metastasis) ikoreshwa cyane: T (Tumor): Sobanura ingano nubunini bwikibyimba cyibanze. N (Node): Yerekana niba kanseri yarakwirakwiriye hafi ya lymph node. M (Metastasis): Yerekana niba kanseri yarakwirakwiriye ahantu kure (metastasis) .Icyiciro kiva kuri I kugeza kuri IV, icyiciro cya IV nicyo cyateye imbere cyane. Amahitamo yo kuvura RCCTreatment ya RCC biterwa nicyiciro cya kanseri, ubuzima bwumurwayi muri rusange, nibindi bintu. Uburyo bwo kuvura bushobora kubamo: Kubaga: Nephrectomy: Gukuraho impyiko zose, ingirabuzimafatizo zikikije, ndetse rimwe na rimwe hafi ya lymph node. Ubu ni bwo buryo bwo kuvura busanzwe RCC. Nephrectomy igice: Kurandura ikibyimba gusa nigice gito cyumubiri ukikije. Ibi bikunze guhitamo kubyimba bito cyangwa mugihe imikorere yimpyiko igomba kubikwa. Igenzura rifatika: Kubibyimba bito, bikura buhoro, kugenzura neza (gutegereza neza) birashobora kuba amahitamo. Ibi bikubiyemo gukurikirana buri gihe hamwe no gupima amashusho kugirango urebe niba ikibyimba gikura. Ubuvuzi bwo gukuraho: Ubu buhanga bukoresha ubushyuhe cyangwa ubukonje kugirango urimbure ikibyimba. Gukuraho Radiofrequency (RFA): Koresha umurongo wa radio kugirango ushushe kandi usenye ikibyimba. Cryoablation: Koresha ubukonje bukabije kugirango uhagarike kandi usenye ikibyimba. Ubuvuzi bugamije: Iyi miti yibasira molekile zihariye zigira uruhare mu mikurire ya kanseri no kubaho. Ubuvuzi busanzwe bugenewe RCC harimo: Inzitizi za VEGF: Nka sunitinib (Sutent), sorafenib (Nexavar), pazopanib (Votrient), axitinib (Inlyta), na cabozantinib (Cabometyx). Iyi miti ihagarika imikurire yimitsi mishya ikibyimba gikeneye gukura. Inhibitor ya mTOR: Nka temsirolimus (Torisel) na everolimus (Afinitor). Iyi miti ihagarika poroteyine yitwa mTOR ifasha selile kanseri gukura no kugabana. HIF-2α Inhibitor: Belzutifan (Welireg) kubarwayi bafite RCC ifitanye isano na VCC. Immunotherapy: Iyi miti ifasha umubiri wumubiri kurwanya kanseri. Ubudahangarwa busanzwe kuri RCC harimo: Inhibitori ya PD-1: Nka nivolumab (Opdivo) na pembrolizumab (Keytruda). Iyi miti ihagarika poroteyine yitwa PD-1 ifasha selile kanseri kwirinda ubudahangarwa bw'umubiri. Inzitizi za CTLA-4: Nka ipilimumab (Yervoy). Uyu muti uhagarika poroteyine yitwa CTLA-4 nayo ifasha selile kanseri kwirinda ubudahangarwa bw'umubiri. Interleukin-2 (IL-2): Cytokine itera ubudahangarwa bw'umubiri. Ubuvuzi bw'imirasire: Imiti ivura imirasire ikoresha imirasire yingufu nyinshi kugirango yice kanseri. Ntabwo isanzwe ikoreshwa kuri RCC, ariko irashobora gukoreshwa mukuvura metastase cyangwa kugabanya ububabare. Ibigeragezo bivura: Kwitabira ibizamini byamavuriro birashobora gutanga uburyo bwo kuvura bushya kandi butanga ikizere.Prognoz ya RCCIbiteganijwe kuri RCC biterwa nibintu byinshi, harimo icyiciro cya kanseri, subtype ya RCC, ubuzima bwumurwayi muri rusange, nubuvuzi bwakiriwe. Kumenya hakiri kare no kuvura nibyingenzi mugutezimbere ibisubizo.Muri rusange, abarwayi bafite aho baherereye RCC (icyiciro I-III) bafite prognoza nziza. Igipimo cyimyaka 5 yo kubaho kurwego I. RCC ni hejuru cyane, akenshi irenga 90%. Ariko, guhanura abarwayi bafite metastatike RCC (icyiciro cya IV) ntabwo ari byiza, hamwe nimyaka 5 yo kubaho hafi 10-20%. Nyamara, uburyo bushya bwo kuvura bugamije kuvura no gukingira indwara bwateje imbere cyane imyumvire y’abarwayi benshi bafite iterambere RCC. Gukomeza ubushakashatsi niterambere mu buvuzi biratanga ibyiringiro byibyiza bizagerwaho mugihe kizaza.Kwirinda RCC Mugihe ntaburyo bwizewe bwo gukumira RCC, urashobora gufata ingamba zo kugabanya ibyago byawe, harimo: Kureka itabi: Niba unywa itabi, kureka ishuri nicyo kintu cyingenzi ushobora gukora kugirango ugabanye ibyago. Komeza ibiro byiza: Kugabanya ibiro niba ufite umubyibuho ukabije cyangwa umubyibuho ukabije birashobora kugabanya ibyago byawe. Kurwanya umuvuduko ukabije w'amaraso: Korana na muganga wawe kugirango ucunge umuvuduko wamaraso. Irinde guhura nibintu bimwe na bimwe: Mugabanye guhura na kadmium na herbiside. Vugana na Muganga wawe kubyerekeye amateka yumuryango: Niba ufite amateka yumuryango wa kanseri yimpyiko, ganira na muganga wawe ibyago byawe.RCC Ubushakashatsi muri Shandong Baofa Research Research InstituteAt Shandong Baofa Ikigo Cyubushakashatsi Kanseri, twiyemeje guteza imbere imyumvire no kuvura RCC. Ubushakashatsi bwacu bwibanze ku guteza imbere ubuvuzi bushya no kunoza ibisubizo ku barwayi bafite iyi ndwara. Twizera ko binyuze mubushakashatsi bukomeje nubufatanye, dushobora guhindura byinshi mubuzima bwabafashwe na kanseri yimpyiko.RCC Gutanga Urugero Icyiciro cya Tumor Ingano (T) Lymph Node (N) Metastasis (M) I T1 (cm 7 cm) N0 M0 II T2 (> cm 7, zigarukira ku mpyiko) N0 M0 III T3. . Baza numuhanga mubuvuzi kugirango ategure neza.RCC: Uburyo bw'abarwayi-bushingiye ku gusobanukirwa ningorabahizi za RCC ni ngombwa mugutahura hakiri kare no gucunga neza. Kuva aho kumenya ingaruka zishobora guterwa no gufata inzira zo kuvura, guha imbaraga abantu bafite ubumenyi bibafasha kuyobora urugendo rwubuzima bwabo neza. Kubuvuzi bwihariye nubushakashatsi bwibanze mu kuvura kanseri, cyane cyane bijyanye RCC, tekereza gushakisha ibikoresho biboneka mubigo nka Shandong Baofa Ikigo Cyubushakashatsi Kanseri.Inshingano: Aya makuru agenewe ubumenyi rusange nintego zamakuru gusa, kandi ntabwo bigize inama zubuvuzi. Ni ngombwa kugisha inama inzobere mu by'ubuzima zibishoboye kubibazo byose byubuzima cyangwa mbere yo gufata ibyemezo byose bijyanye n'ubuzima bwawe cyangwa kwivuza.Inkomoko: Umuryango w'Abanyamerika Kanseri: www.cancer.org Ikigo cy'igihugu cya kanseri: www.cancer.gov Ivuriro rya Mayo: www.mayoclinic.org