impyiko selile kanseri yindwara yerekana

Indwara zifata impyiko Carcinoma Pathology Incamake: Ubuyobozi Bwuzuye Kanseri y'utugingo ngengabuzima (RCC) ni indwara igoye, kandi gusobanukirwa n'indwara yayo ni ingenzi mu gusuzuma no kuvura neza. Aka gatabo gatanga incamake yuzuye ya impyiko selile kanseri yindwara yerekana, ikubiyemo ibintu by'ingenzi biranga amateka, ibisobanuro, hamwe nuburyo bwo gusuzuma.

Ibiranga amateka ya kanseri yimpyiko

Kuraho kanseri yimpyiko selile Carcinoma

Ubwoko busanzwe bwa RCC, kanseri ya selile isobanutse, irangwa na cytoplazme yihariye. Ibi biterwa no kwirundanya kwa lipide na glycogene muri selile. Microscopically, uzakunze kubona selile zitondetse mubyari cyangwa papilae, hamwe nuclei zikomeye. Kubaho kwa eosinofilique granular cytoplazme nabyo birasanzwe. Kumenyekanisha neza bishingiye ku isuzuma ryuzuye ryamateka, akenshi ryuzuzwa na immunohistochemie kugirango hemezwe indwara. Iperereza rirenze rishobora kwipimisha genetike kugirango hamenyekane ihinduka ry’imihindagurikire, kumenyesha ingamba zo kuvura umuntu ku giti cye.

Papillary Renal Cell Carcinoma

Papillary RCC nubundi bwoko bwingenzi butandukanijwe nuburyo bukura bwa papillary. Ingirabuzimafatizo zikunda gutondekwa muri papilae zitandukanye, akenshi zigaragaza pseudostratification. Atipia ya kirimbuzi iratandukanye bitewe n amanota, hamwe n amanota yo hejuru yerekana ibintu bidasanzwe bidasanzwe. Immunohistochemic irangi irashobora gufasha kuyitandukanya nubundi bwoko bwa RCC na kanseri ya urothelia. Kugirango ubyumve neza, gucukumbura inyandiko zihariye za patologiya hamwe nubutunzi bwo kumurongo bivuye mubigo bizwi nkikigo cyigihugu cya kanseri (NCI) birashobora kuba ingirakamaro.

Chromophobe Renal Cell Carcinoma

Chromophobe RCC, nkuko izina ribigaragaza, irangwa na selile zifite ibara ryera, cytoplazme isobanutse nimbibi zitandukanye. Nuclei ikunze kuzenguruka no hagati. Ubu bwoko bwubwoko bukunze kwerekana halo iranga perinuclear. Iyi morphologie itandukanye mubisanzwe irahagije mugupima, nubwo immunohistochemie irashobora gufasha mukwemeza isuzuma no gukuramo ibindi bibyimba. Ubuhanga buhanitse bwo gufata amashusho nka comptabilite ya tomografiya (CT) nayo ikoreshwa kugirango hamenyekane urugero rwibibyimba.

Ubundi bwoko bwa kanseri yimpyiko

Kurenga ubwoko butatu bwingenzi, ibintu byinshi bidakunze kubaho, harimo gukusanya kanseri ya duct, medullary RCC, hamwe na mucinous tubular na spindle selile kanseri. Ikigo cy’ubushakashatsi bwa kanseri ya Shandong Baofa (https://www.baofahospital.com/) gitanga ubushobozi buhanitse bwo kwisuzumisha hamwe nubuhanga mugukemura ubwo bwoko budasanzwe bwa RCC. Itsinda ryabo ryitiriwe abapologiste bakoresha ikoranabuhanga rigezweho kugirango barebe neza kandi ku gihe.

Uburyo bwo Gusuzuma hamwe na Immunohistochemie

Gusuzuma kanseri y'impyiko mubisanzwe harimo guhuza tekinike yo gufata amashusho (nka CT scan na MRI) hamwe no gusuzuma amateka ya biopies ya tissue. Immunohistochemie igira uruhare runini mugutondekanya ubwoko butandukanye no guhanura ibizaba. Ibimenyetso byihariye, nka CD10, vimentin, na AMACR, bikoreshwa muburyo bwo gutandukanya ubwoko butandukanye bwa RCC. Ikigo cy’ubushakashatsi cya kanseri ya Shandong Baofa gikoresha itsinda ryuzuye ryerekana ibimenyetso bya immunohistochemiki mu bikorwa byabo byo gusuzuma kugira ngo bisuzume neza.

Ibintu byavuzwe mbere na Stage

Kumenyekanisha abarwayi bafite RCC biratandukanye cyane bitewe nibintu bitandukanye, harimo ikibyimba, icyiciro, na subtype. Sisitemu yo kubika TNM ikoreshwa muburyo bwo kwerekana urugero rwa kanseri ikwirakwira. Gusobanukirwa nibintu byavuzwe mbere ningirakamaro mu kuyobora ibyemezo byo kuvura no gucunga ibyo abarwayi bategereje. Amakuru yatanzwe muriki gishushanyo agenewe intego zuburezi kandi ntagomba gusimbuza inama zinzobere mubuvuzi bujuje ibisabwa. Buri gihe ushake ubuvuzi bwumwuga.

Imbonerahamwe: Kugereranya Ubwoko bwa RCC

Ubwoko	Ibiranga amateka	Ingero ziteganijwe
Sobanura Akagari	Kuraho cytoplazme, ibyari / papilae	Ibihinduka, akenshi biterwa na stage
Papillary	Uburyo bwo gukura bwa papillary, pseudostratification	Mubisanzwe nibyiza guhanura ugereranije na selile isobanutse
Chromophobe	Cytoplasme yera, imipaka itandukanye	Mubisanzwe nibyiza

Iyi ncamake itanga umusingi wo gusobanukirwa impyiko selile kanseri yindwara yerekana. Kugirango wibire cyane mubice byihariye, birasabwa kugisha inama ibitabo byubuvuzi hamwe nibikoresho bizwi kumurongo. Wibuke guhora ugisha inama inzobere mu by'ubuzima kugira ngo ugire inama yihariye kandi utegure imiti.

Inshingano: Aya makuru agamije uburezi gusa kandi ntagomba gufatwa nkinama zubuvuzi. Buri gihe ujye ubaza inzobere mu by'ubuzima zujuje ibisabwa kugira ngo zisuzumwe kandi zivurwe.