kuvura kanseri yimpyiko

Umuti wa kanseri yimpyiko (RCC) ikubiyemo uburyo butandukanye, harimo kubaga, kuvura intego, kuvura indwara, no kuvura imirasire. Guhitamo kwivuza Biterwa nibintu nkicyiciro cya kanseri, ubuzima bwumurwayi muri rusange, hamwe nibyifuzo bye. Kumenya hakiri kare no gutabara mugihe ningirakamaro mugutezimbere ibisubizo. Kumva kanseri yimpyikoKanseri y'impyiko (RCC) ni ubwoko bwa kanseri y'impyiko ikuze. Ikomoka kumurongo wa tubule yegeranye cyane, igice cyimpyiko zungurura amaraso kandi kigakuraho imyanda. Nubwo impamvu nyayo itera RCC itajya isobanuka neza, ibintu bimwe bishobora gutera ingaruka ziterwa no kwiyongera kwindwara. Izi mpamvu zishobora guteza akaga harimo kunywa itabi, umubyibuho ukabije, umuvuduko ukabije w'amaraso, hamwe n'indwara zikomoka ku bwoko nka von Hippel-Lindau (VHL). Kuri Shandong Baofa Ikigo Cyubushakashatsi Kanseri, twiyemeje gutanga amakuru yuzuye kandi yateye imbere kwivuza amahitamo kubarwayi ba RCC.Ubwoko bwa Carcinoma Yimpyiko Hariho ubwoko butandukanye bwa RCC, buri kimwe gifite imiterere itandukanye nibisubizo bitandukanye kuri kwivuza. Ubwoko bukunze kugaragara harimo: Sobanura selile RCC: Ubu ni bwo bwoko bwiganje cyane, bingana na 70-80% by'imanza. Papillary RCC: Ubwoko bwa kabiri bukunze kugaragara, bugereranya hafi 10-15% yimanza. Chromophobe RCC: Ubwoko buto busanzwe, bugizwe na 5% byimanza. Gukusanya umuyoboro RCC: Uburyo budasanzwe kandi bukaze bwa RCC.Amahitamo yo kuvura kanseri yimpyiko kwivuza uburyo bwa RCC buterwa nibintu byinshi, harimo icyiciro cya kanseri, ubuzima bwumurwayi muri rusange, hamwe nubwoko bwihariye bwa RCC. Bisanzwe kwivuza muburyo burimo kubaga, kuvura bigamije, gukingira indwara, no kuvura imirasire. kuvura kanseri yimpyiko, cyane cyane iyo kanseri yegereye impyiko. Amahitamo yo kubaga arimo: Nephrectomy ikabije: Ibi bikubiyemo gukuraho burundu impyiko zanduye, hamwe nuduce dukikije nka glande ya adrenal na lymph node. Nephrectomy igice: Ibi bikubiyemo kuvanaho ikibyimba gusa nuduce duto duto twiza, kubika impyiko nyinshi zishoboka. Ubu buryo busanzwe bukundwa kubibyimba bito cyangwa mugihe umurwayi afite impyiko imwe gusa. Intego yo kuvuraIbikoresho bigamije kuvura ni imiti yibasira molekile zigira uruhare mu mikurire ya kanseri no kubaho. Ubu buryo bwo kuvura bushobora kuba ingirakamaro cyane muri RCC yateye imbere. Ubuvuzi busanzwe bugamije harimo: Inzitizi za VEGF: Iyi miti ihagarika inzira yo gukura kw'imitsi y'amaraso (VEGF), ikaba ari ngombwa mu gushiraho imiyoboro mishya y'amaraso itanga ibibyimba. Ingero zirimo sunitinib (Sutent), sorafenib (Nexavar), pazopanib (Votrient), axitinib (Inlyta), na cabozantinib (Cabometyx). mTOR inhibitor: Iyi miti ibuza inyamaswa z’inyamabere inzira ya rapamycine (mTOR), igenga imikurire ya selile na metabolism. Ingero zirimo temsirolimus (Torisel) na everolimus (Afinitor) .ImmunotherapyImmunotherapy ikoresha imbaraga z'umubiri w’umubiri urwanya kanseri. Imiti ikingira indwara ya RCC irimo: Immune igenzura: Iyi miti ihagarika poroteyine zibuza umubiri kwirinda indwara ya kanseri. Ingero zirimo nivolumab (Opdivo), pembrolizumab (Keytruda), ipilimumab (Yervoy), na atezolizumab (Tecentriq). Nivolumab ikunze guhuzwa na ipilimumab kubwindwara zateye imbere. Cytokines: Dose-interleukin-2 (IL-2) na interferon-alpha (IFN-α) ni cytokine ishobora gutera imbaraga z'umubiri. Nyamara, iyi miti irashobora kugira ingaruka zikomeye kandi ntigikoreshwa cyane muri iki gihe kubera ko haboneka imiti mishya yubuvuzi. Ntabwo aribisanzwe kuvura kanseri yimpyiko, ariko irashobora gukoreshwa mugucunga ububabare cyangwa ibindi bimenyetso biterwa na kanseri yateye imbere yakwirakwiriye mubindi bice byumubiri. Rimwe na rimwe ikoreshwa nyuma yo kubagwa niba hari ibyago kanseri izagaruka cyangwa niba bimwe mubyimba bidashobora kuvaho. Ubuvuzi bwa stereotactique yumubiri (SBRT) butanga urugero rwinshi rwimirasire ahantu hagenewe neza kandi rimwe na rimwe bikoreshwa mubibyimba byimpyiko.Icyiciro cya kanseri yimpyiko na kuvura Icyiciro cya RCC nikintu cyingenzi muguhitamo igikwiye kwivuza inzira. Icyiciro gishingiye ku bunini n'aho ikibyimba giherereye, cyaba cyarakwirakwiriye mu mitsi ya lymph hafi, ndetse no kuba cyarageze ku ngingo za kure.Icyiciro cya I Renal Cell Carcinoma Ikibyimba kigarukira ku mpyiko kandi gifite cm 7 cyangwa munsi ya diameter. Umuti mubisanzwe bikubiyemo kubaga ikibyimba, haba mubice cyangwa bikabije nephrectomy.Icyiciro cya kabiri Carcinoma Cell Renal Cell Ikibyimba kinini kirenze cm 7 ariko kiracyafite impyiko. Umuti mubisanzwe birimo nephrectomy. Umuti Irashobora kuba irimo nephrectomy radical, lymph node dissection, hamwe nibishoboka bivura (urugero, kuvura intego cyangwa immunotherapie) .Icyiciro cya IV Carcinoma Cell Renal kanseri yibasiye ingingo za kure, nk'ibihaha, amagufwa, cyangwa ubwonko. Umuti amahitamo arashobora kubamo gukuramo ikibyimba cyibanze (cytoreductive nephrectomy), kuvura intego, immunotherapy, kuvura imirasire, cyangwa guhuza ubu buryo. Igeragezwa rya Clinical naryo rishobora kuba amahitamo. Kubana na kanseri yimpyiko Carcinoma Kubana na RCC birashobora kwerekana ibibazo bitandukanye, haba kumubiri no mumarangamutima. Ni ngombwa kugira sisitemu ikomeye yo gushyigikira no kubona ubuvuzi bwuzuye. Abarwayi barashobora guhura n'ingaruka ziva kwivuza, nk'umunaniro, isesemi, impiswi, no kurwara uruhu. Gukemura izo ngaruka ni igice cyingenzi cyo kwita kuri kanseri. Byongeye kandi, gukomeza ubuzima buzira umuze, harimo indyo yuzuye hamwe na siporo isanzwe, birashobora gufasha kuzamura imibereho myiza muri rusange. Mu kigo cy’ubushakashatsi bwa kanseri ya Shandong Baofa, itsinda ryacu ryitanze ritanga ubuvuzi bwimpuhwe kandi bwihariye kwivuza gahunda yo gufasha abarwayi gucunga RCC yabo no kuzamura imibereho yabo. Turi mu gace ka Jinan Innovation Zone, kandi ubutumwa bwacu bujyanye n’ingamba za 'Made in China 2025'. kwivuza ihora itera imbere, hamwe nubuvuzi bushya nuburyo butezwa imbere. Iterambere rya vuba ririmo: Gukingira Immunotherapy: Gukomatanya imiti itandukanye yubudahangarwa, nka nivolumab na ipilimumab, yerekanye umusaruro ushimishije mubarwayi bamwe na bamwe bafite RCC yateye imbere. Kunoza imiti igamije: Ibisekuru bishya byubuvuzi bugamije gutezwa imbere hamwe no kunoza imikorere ningaruka nke. Ubuvuzi bwihariye: Abashakashatsi barimo gukora kugirango bamenye ibinyabuzima bishobora gufasha kumenya abarwayi bashobora kwitabira byihariye kwivuza. kwivuza. Kumenya hakiri kare no gutabara mugihe ningirakamaro mugutezimbere ibisubizo. Abarwayi bafite RCC yaho babazwe bafite amahirwe menshi yo gukira. Ariko, guhanura ntabwo ari byiza kubarwayi bafite RCC yateye imbere. Ubushakashatsi burimo kwibanda ku guteza imbere ibishya kandi byiza kwivuzas kunoza imenyekanisha kubarwayi bose barwaye RCC.Igeragezwa rya Clinical Ibigeragezo bya kliniki ni ubushakashatsi bwubushakashatsi busuzuma ibishya kwivuzas cyangwa inzira ya RCC. Kwitabira ikizamini cyamavuriro birashobora gutanga uburyo bwo kuvura butaraboneka henshi. Abarwayi bashishikajwe no kumenya byinshi kubyerekeye ibizamini byo kwa muganga bagomba kuvugana na muganga wabo.Urugero rwamakuru: Igipimo cyo Kurokoka Icyiciro Icyiciro Cyimyaka 5 yo Kurokoka Icyiciro I 81-93% Icyiciro II 74-91% Icyiciro cya III 53-83% Icyiciro cya IV 8-20% Inkomoko: Sosiyete y'Abanyamerika Kanseri (www.cancer.org)