inshuro eshatu kanseri y'ibere

Kanseri y'ibere inshuro eshatu: Ubuyobozi BwuzuyeGusobanukirwa Kanseri y'ibere inshuro eshatu-mbi: Igitabo cy'umurwayiTriple-negative kanseri y'ibere (TNBC) ni ubwoko bwa kanseri y'ibere itagaragaza imiti ya estrogene, progesterone, cyangwa HER2. Uku kubura kwakirwa bituma bitera ubukana kandi bigoye kuvura ugereranije nubundi bwoko bwa kanseri yamabere. Aka gatabo gatanga incamake yuzuye ya inshuro eshatu kanseri y'ibere, ikubiyemo ibiranga, gusuzuma, uburyo bwo kuvura, hamwe nibikoresho byunganira. Dufite intego yo kuguha imbaraga nubumenyi no gusobanukirwa kugirango uyobore uru rugendo rutoroshye.

Gusobanukirwa Ibiranga TNBC

Niki gitandukanya TNBC?

Bitandukanye n'ubundi bwoko bwa kanseri y'ibere, inshuro eshatu kanseri y'ibere ibura reseptor ya estrogene (ER), reseptor ya progesterone (PR), hamwe na reseptor ya epidermal yo gukura kwabantu 2 (HER2). Aba reseptors bakunze kwibasirwa no kuvura izindi kanseri yamabere, ariko kubura kwabo muri TNBC bigabanya uburyo bwo kuvura. Ibi akenshi biganisha kumasomo yindwara ikaze kandi ibyago byinshi byo kongera kubaho.

Ikwirakwizwa ningaruka ziterwa

Kanseri y'ibere inshuro eshatu bingana na 10-20% bya kanseri zose. Impamvu zishobora gutera TNBC zirimo imyaka mike mugupima, ihinduka rya gene ya BRCA1, ubwoko bwabanyamerika, hamwe namateka yumuryango wa kanseri yibere. Nyamara, abagore benshi basuzumwe na TNBC nta mpamvu zishobora guterwa.

Gusuzuma no Gutunganya TNBC

Uburyo bwo Gusuzuma

Gusuzuma inshuro eshatu kanseri y'ibere mubisanzwe birimo biopsy yo gusuzuma selile yibibyimba munsi ya microscope. Ibizamini bya Immunohistochemical (IHC) byerekana ko ER, PR, na HER2 byakira. Ibindi bizamini, nka amashusho yerekana amashusho (mammografiya, ultrasound, MRI), birashobora gukoreshwa mugupima urugero rwa kanseri.

Gutegura no Kumenyekanisha

Gutegura byerekana ubunini bwa kanseri, bigira ingaruka ku byemezo byo kuvura no guhanura. Sisitemu yo kubika TNM ikoreshwa cyane, gusuzuma ingano yibibyimba (T), uruhare rwa lymph node (N), hamwe na metastasis ya kure (M). Guteganya TNBC biratandukanye bitewe na stade nibindi bintu; gutahura hakiri kare no kuvurwa mugihe ningirakamaro mugutezimbere ibisubizo.

Amahitamo yo kuvura TNBC

Kubaga

Kubaga akenshi niwo murongo wambere wo kuvura inshuro eshatu kanseri y'ibere, ugamije gukuraho ikibyimba cya kanseri. Ibi birashobora kuba birimo lumpectomy (gukuramo ikibyimba) cyangwa kwikinisha (gukuramo ibere). Sentinel lymph node biopsy cyangwa gutandukanya lymph node irashobora gukorwa kugirango isuzume uruhare rwa lymph node.

Chimoterapi

Chimoterapi ni urufatiro rwo kuvura TNBC, akenshi ikoreshwa mbere yo kubagwa (neoadjuvant chemotherapie) kugirango igabanye ikibyimba cyangwa nyuma yo kubagwa (chimiotherapie adjuvant) kugirango igabanye ibyago byo kongera kubaho. Uburyo butandukanye bwa chimiotherapie burahari, bwatoranijwe bushingiye kubintu bitandukanye. Ubushakashatsi ikomeje gushakisha uburyo bushya bwa chimiotherapie ihuza kunoza imikorere.

Ubuvuzi

Imiti ivura imirasire ikoresha imirasire yingufu nyinshi kugirango yice selile. Bikunze gukoreshwa nyuma yo kubagwa kugirango isenye selile zose zisigaye mu ibere cyangwa hafi ya lymph node. Irashobora kandi gukoreshwa mu kuvura indwara metastatike.

Ubuvuzi bugenewe hamwe na Immunotherapy

Mugihe TNBC ititabira kuvura imisemburo cyangwa kuvura HER2, ubushakashatsi burakomeje mubuvuzi bugenewe no gukingira indwara. Bumwe mu buryo bwo kuvura bwibanda ku nzira zihariye zigira uruhare mu mikurire ya TNBC, mu gihe imiti ikingira indwara igamije kongera ubudahangarwa bw'umubiri mu kurwanya kanseri. Ubu buvuzi bwerekana amasezerano ariko buracyakurikiranwa.

Kubana na Hanze ya TNBC

Gukurikirana Kwitaho

Gahunda yo gukurikirana buri gihe ni ngombwa nyuma yo kuvurwa kugirango ikurikirane ibisubirwamo. Iyi gahunda mubusanzwe ikubiyemo kwisuzumisha kumubiri, gusikana amashusho, no gupima amaraso. Kumenya hakiri kare ibyingenzi nibyingenzi mugucunga neza.

Inkunga n'umutungo

Guhangana no gusuzuma inshuro eshatu kanseri y'ibere birashobora kuba ingorabahizi. Inkunga ituruka mumuryango, inshuti, hamwe nitsinda ryamatsinda ni ntagereranywa. Amashyirahamwe menshi atanga ibikoresho ninkunga kubantu barebwa na TNBC. Tekereza kuvugana na Shandong Baofa Ikigo Cyubushakashatsi Kanseri kubindi bisobanuro hamwe nibikoresho. Batanga ubuvuzi bwuzuye bwa kanseri, harimo ubuhanga bwo kuvura ubwoko butandukanye bwa kanseri y'ibere.

Ubundi bushakashatsi nubushakashatsi bwa Clinical

Ubushakashatsi muri inshuro eshatu kanseri y'ibere ihora itera imbere, hamwe nibigeragezo byamavuriro bikurikirana ingamba nshya zo kuvura no kunoza ibisubizo. Oncologue wawe arashobora kuganira kubishobora kwitabira ibizamini byamavuriro bishobora kuba bihuye nibihe byihariye. Gukomeza kumenyeshwa ibyagezweho mubushakashatsi bwa TNBC ni ngombwa.