Horumarka daaweynta kansarka sanbabada cusub 2020

Sannadka 2020, horumarro la taaban karo ayaa laga sameeyay daawaynta kansarka sanbabada, oo ay ku jiraan oggolaanshaha daawaynta cusub ee la beegsaday iyo immunotherapy, oo siinaya natiijooyin la wanaajiyey iyo habab shakhsiyeed oo loogu talagalay bukaannada. Horumarradan waxay siiyeen doorashooyin cusub kuwa la dagaallamaya kansarka sanbabada, wax ka qabashada isbeddellada hidde-sidaha ee gaarka ah iyo kor u qaadista jawaabta difaaca jirka si uu ula dagaallamo cudurka. Sannadka Horumarka: Furaha Horumar Cusub oo Daaweynta Kansarka Sambabada 20202020 waxay calaamad u ahayd sanad muhiim ah oo la dagaalanka kansarka sanbabada. Iyadoo sanadka uu ahaa mid ay u badan tahay masiibada caalamiga ah, cilmi-baarayaasha iyo daaweeyayaasha waxay sii wadeen inay riixaan xuduudaha doorashooyinka daaweynta. Dhawr horumar oo rajo leh ayaa soo baxay, kuwaas oo rajo siinaya bukaanada iyo dib u qaabaynta muuqaalka daryeelka kansarka sanbabada. Machadka Cilmi-baarista Kansarka ee Shandong Baofa ayaa si dhow ula socday horumarkan. Daaweynta La Beegsaday: Horumarka Daawada Saxda ah, ee loogu talagalay in lagu weeraro daciifnimada gaarka ah ee unugyada kansarka, waxay arkeen horumar la taaban karo 2020. daawayntan waxay inta badan keenaan waxyeellooyin yar marka loo eego kiimoterabiga dhaqameed sababtoo ah waxay si sax ah u beegsadaan unugyada kansarka si sax ah. Kansarka sambabada unugyada aan yarayn (NSCLC). Sannadka 2020, hor-joogayaasha cusub ee EGFR ee la hagaajiyay ayaa la ansixiyay, iyagoo siinaya badbaado-horumar-la'aaneed oo wanaagsan bukaannada leh isbeddelladan. Kahortagayaasha jiilka cusub waxay inta badan ka gudbaan hababka iska caabbinta ee xaddidaya waxtarka daawooyinka hore. Gaar ahaan, wakiilada bartilmaameedsanaya EGFR exon 20 is-beddelka gelinta ayaa muujiyay waxqabad rajo leh. Tusaale ahaan, mid ka mid ah wakiilkan waa amivantamab. Jadwalka soo socdaa wuxuu tusinayaa natiijooyinka tijaabooyinka caafimaad ee amivantamab: Heerka Jawaabta Guud ee Wajiga tijaabada (ORR) Muddada Jawaabta (DoR) Wajiga I 40% 11.1 bilood Isha: FDAKahortagayaasha ALK: Balaadhinta Ikhtiyaarada Daaweynta. Dhowr alK inhibitors ayaa horayba loo heli jiray, iyo 2020, cilmi-baaris ayaa diiradda lagu saaray ka-hortagga iska caabbinta daawooyinkan iyo horumarinta ka-hortagga awood badan. Daawooyinka isku dhafan ee cusub ayaa sidoo kale la sahamiyay si loo hagaajiyo natiijooyinka ALK-positive cancer cancer. daaweynta kansarka sambabada sare. 2020, daraasaduhu waxay sahamiyeen isticmaalka daawooyinkan marxaladihii hore ee cudurka, oo ay ku jiraan qalliinka ka dib ama lagu daro kiimoterabi. Daraasadahani waxay muujiyeen in immunotherapy ay hagaajin karto heerarka badbaadada oo ay yarayn karto khatarta soo noqoshada bukaannada qaarkood. Isku-dhafka Immunotherapy RegimensResearchers ayaa sidoo kale baaritaan ku sameeyay isku-darka daawooyinka immunotherapy ee kala duwan si kor loogu qaado waxtarkooda. Xayiraadda laba-koontorool, iyadoo la adeegsanayo laba nooc oo kala duwan oo ah isbaarada isbaarada difaaca, ayaa muujisay ballanqaad bukaannada qaarkood oo aan ka jawaabin tallaalka difaaca jirka ee hal wakiil ah. Tijaabooyinka caafimaadku waxay sii wadeen si ay u nadiifiyaan hababkan isku dhafan si loo aqoonsado bukaanada ay u badan tahay inay ka faa'iidaystaan. Doorka Tijaabada Biomarker Horumarka daaweynta la beegsaday iyo daaweynta difaaca jirka ayaa muujisay muhiimada baaritaanka biomarker dhamaystiran ee kansarka sanbabada. Sannadka 2020, waxaa sare loo sii qaaday xoogga la saarayo tijaabinta noocyo badan oo isbeddel hidde ah iyo muujinta PD-L1 si loo hago go'aannada daawaynta. Habkan shakhsi ahaaneed ayaa hubinaya in bukaanku helaan daaweynta ugu habboon uguna waxtarka badan ee kansarka gaarka ah.Shandong Baofa Institute Research Institute ayaa xooga saaraysa muhiimada baaritaan dhamaystiran si loo gaaro natiijooyinka ugu fiican. Horumarrada cusub ee daaweynta kansarka sanbabada 2020 waxay u gogol xaaraysay horumar intaa ka sii badan sanadaha soo socda. Cilmi-baarista socota waxay diiradda saareysaa horumarinta daawayn cusub oo la beegsanayo, hagaajinta xeeladaha difaaca jirka, iyo aqoonsiga biomarkers cusub. Hadafka kama dambaysta ahi waa in la horumariyo daawaynta waxtarka leh iyo kuwa gaarka loo leeyahay kuwaas oo wanaajiya heerarka badbaadada iyo tayada nolosha ee dhammaan bukaannada qaba kansarka sanbabada. Gabagabada2020 waxay ahayd sannad horumarro la taaban karo laga gaaray daaweynta kansarka sanbabada. Oggolaanshaha daawaynta cusub ee la beegsanayo iyo daaweynta difaaca jirka, oo ay weheliso xoojinta xoojinta baaritaanka biomarker, ayaa beddelay muuqaalka daryeelka kansarka sanbabada. Horumarradan ayaa rajo siiya bukaannada iyo qoysaskooda waxayna muujinayaan muhiimadda ay leedahay sii wadida cilmi-baarista iyo hal-abuurka la dagaallanka cudurkan ba'an. Tixgeli booqashada Shandong Baofa Machadka Cilmi-baarista Kansarka website-ka si aad u hesho macluumaad dheeraad ah oo ku saabsan tijaabooyinka caafimaad iyo daawaynta kansarka horumarsan.