I-China isigaba sesi-3 sokwelashwa komdlavuza wamaphaphu

Ukuqonda Nokwelapha Isigaba 3A Umdlavuza Wamaphaphu eChina

Lo mhlahlandlela ophelele uhlola ubunkimbinkimbi be I-China isigaba sesi-3 sokwelashwa komdlavuza wamaphaphu, ehlinzeka ngemininingwane mayelana nokuxilongwa, izinketho zokwelapha, kanye nentuthuko yakamuva ekunakekelweni kwe-oncology ngaphakathi kwe-China. Sizofaka izindlela zokwelashwa ezahlukahlukene, imiphumela engemihle engaba khona, kanye nokubaluleka kokufuna izeluleko zezokwelapha zochwepheshe eziklanyelwe izimo zakho ezithile.

Ukuxilongwa Kwesigaba 3A Umdlavuza Wamaphaphu

Ukuqonda Uhlelo Lwesiteji

Isiteji esinembayo sibalulekile ekunqumeni indlela yokwelashwa engcono kakhulu I-China isigaba sesi-3 somdlavuza wamaphaphu. Isigaba 3A sibonisa ukuthi umdlavuza ususabalele kuma-lymph nodes aseduze kodwa hhayi ezingxenyeni ezikude zomzimba. Lesi sigaba siphinde sihlukaniswe (3A vs 3B) ngokusekelwe ezingeni lokubandakanyeka kwe-lymph node. Ukuxilongwa okunembile kuhilela ukuhlolwa okuhlukahlukene okuhlanganisa izikena ze-imaging (CT, PET), ama-biopsies, ne-bronchoscopy. Ukuxilongwa kusenesikhathi nokunembile kubathinta kakhulu amazinga empumelelo yokwelashwa.

Amathuluzi Nezinqubo Zokuxilonga

Kusetshenziswa izindlela ezimbalwa ezithuthukile zokuthwebula izithombe ekuxilongeni umdlavuza wamaphaphu eChina. Izikena ze-Computed tomography (CT) zinikeza izithombe ezinemininingwane yamaphaphu nezicubu ezizungezile, kuyilapho izikena ze-positron emission tomography (PET) zisiza ukukhomba izinga lokusabalala komdlavuza. Ama-Biopsies, ahilela ukukhishwa kwesampula yethishu ukuze kuhlolwe i-microscopic, abalulekile ukuze kuqinisekiswe ukuxilongwa kanye nokunquma uhlobo lomdlavuza wamaphaphu.

Izinketho Zokwelashwa ZeSigaba 3A Umdlavuza Wamaphaphu

Ukuhlinzwa Kwesigaba 3A Umdlavuza Wamaphaphu

Ukuhlinzwa kungase kube inketho yeziguli ezikhethwe ngokucophelela ezinomdlavuza wamaphaphu wesigaba 3A, ikakhulukazi lezo ezinokubandakanyeka okulinganiselwe kwama-lymph node. Uhlobo lokuhlinzwa olwenziwa luncike endaweni kanye nobukhulu besimila. Lokhu kungase kuhilele i-lobectomy (ukususwa kwe-lobe yamaphaphu), i-pneumonectomy (ukususwa kwephaphu lonke), noma izinqubo ezingathí sina kakhulu. Indlela yokuhlinza ekhethiwe inqunywa ithimba lezinhlaka eziningi lodokotela abahlinzayo, odokotela abahlinzayo, nabanye ochwepheshe.

I-Chemotherapy Esigabeni 3A Ukwelashwa Komdlavuza Wamaphaphu

I-Chemotherapy idlala indima ebalulekile ekwelapheni I-China isigaba sesi-3 somdlavuza wamaphaphu, evame ukusetshenziswa ngaphambi kokuhlinzwa (ukwelashwa ngamakhemikhali kwe-neoadjuvant) ukuze kuncishiswe isimila noma ngemva kokuhlinzwa (i-adjuvant chemotherapy) ukuze kuncishiswe ingozi yokuphindeka. Kunezinhlobo ezahlukene zemithi yokwelapha ngamakhemikhali, ngayinye iklanyelwe isimo sesiguli ngasinye. Ukukhethwa kwezidakamizwa kanye nomthamo wazo kusekelwe ezintweni ezifana nohlobo lwamangqamuzana omdlavuza, impilo iyonke, nokunye ukucatshangelwa kwezokwelapha.

Ukwelapha Ngemisebe Yesigaba 3A Umdlavuza Wamaphaphu

Ukwelashwa ngemisebe, kusetshenziswa imishayo enamandla amakhulu ukucekela phansi amangqamuzana omdlavuza, kuvame ukusetshenziswa kuhlanganiswe nokwelashwa ngamakhemikhali noma ukuhlinzwa komdlavuza wamaphaphu wesigaba 3A. Ukwelashwa ngemisebe yangaphandle kuwuhlobo olusetshenziswa kakhulu, oluqondise isimila nama-lymph node azungezile. Uhlelo oluthile lwemisebe luklanywe ngokucophelela ukunciphisa ukulimala kwezicubu ezinempilo ngenkathi kukhulisa ukucekelwa phansi kwamangqamuzana omdlavuza.

Ukwelashwa Okuhlosiwe kanye ne-Immunotherapy

Izindlela zokwelapha ezihlosiwe kanye ne-immunotherapies zimelela intuthuko enkulu ekwelashweni komdlavuza. Izindlela zokwelapha ezihlosiwe zigxila kuma-molecule athile ahilelekile ekukhuleni komdlavuza, kuyilapho ama-immunotherapies ehlanganisa amasosha omzimba ukuze alwe namaseli omdlavuza. Ukufaneleka kwalokhu kwelashwa kuncike ezintweni ezihlukahlukene, okuhlanganisa ukuguqulwa kofuzo okukhethekile kanye nempilo yonke yesiguli. Lezi zindlela zokwelapha zivame ukuhlanganiswa ne-chemotherapy noma i-radiation therapy ukuze kuthuthukiswe imiphumela. I-Shandong Baofa Cancer Research Institute iyisikhungo esihamba phambili sokwelashwa komdlavuza okuthuthukile sisebenzisa lezi zindlela.

Ukukhetha Uhlelo Lokwelapha Olulungile

Ukukhetha uhlelo olufanele lokwelashwa I-China isigaba sesi-3 somdlavuza wamaphaphu kuyinqubo yokuhlanganyela ehlanganisa isiguli, i-oncologist, kanye nethimba lemikhakha eminingi. Leli thimba lingafaka odokotela abahlinzayo, odokotela be-radiation oncologists, odokotela bezempilo, odokotela bezifo, nabanye ochwepheshe bezempilo. Izinto ezinomthelela ezinqumweni zokwelashwa zihlanganisa iminyaka yesiguli, impilo iyonke, uhlobo nesigaba somdlavuza, kanye nezinto azithandayo. Ingxoxo ebanzi yezinzuzo ezingaba khona, izingozi, kanye nemiphumela engemihle yendlela ngayinye yokwelashwa ibalulekile ekwenzeni isinqumo esinolwazi.

Ukuhlala Nokudlula Isigaba 3A Umdlavuza Wamaphaphu

Ukuphila kanye nangaphezulu kokuhlonzwa kwesigaba 3A somdlavuza wamaphaphu ngokuvamile kudinga indlela ephelele ehlanganisa ukwelashwa, ukusekelwa ngokomzwelo, nokulungiswa kwendlela yokuphila. Ukuqokwa kokulandelela njalo kubalulekile ukuze kuqashwe impendulo yokwelashwa futhi kutholwe noma yikuphi ukuphindeka. Amaqembu okusekela kanye nezinsizakalo zokwelulekwa zinganikeza ukusekelwa okubalulekile ngokomzwelo nokungokoqobo ngalesi sikhathi esiyinselele. Ukugcina indlela yokuphila enempilo, okuhlanganisa ukudla okulinganiselayo, ukuvivinya umzimba njalo, nezindlela zokulawula ukucindezeleka, kungathuthukisa kakhulu izinga lempilo.

Umshwana wokuzihlangula: Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi akufanele luthathwe njengeseluleko sezokwelapha. Hlala uthintana nochwepheshe bezempilo abaqeqeshiwe ukuze uxilongwe futhi ulashwe noma yisiphi isimo sezempilo.