umdlavuza wamanyikwe

Umdlavuza wamanyikwe yisifo lapho amaseli abulalayo akheka khona ezicutshini ze amanyikwe, isitho esitholakala ngemuva kwesisu. Nakuba kungase kube ukuxilongwa okungathi sína, ukutholakala kusenesikhathi kanye nokuthuthuka ekwelashweni kunikeza ithemba. Lesi sihloko sihlola izimpawu, izici eziyingozi, izinqubo zokuxilonga, nezinketho zokwelapha ezitholakalayo umdlavuza wamanyikwe.Ukuqonda I-Pancreas kanye Nomdlavuza WamanyikweThe amanyikwe ibalulekile ekugayeni ukudla kanye nokulawula ushukela egazini. Ikhiqiza ama-enzyme aphula ukudla namahomoni afana ne-insulin elawula amazinga kashukela egazini. Umdlavuza wamanyikwe kwenzeka lapho amaseli ku amanyikwe shintsha futhi ukhule ngokungalawuleki, kwakheka isimila. Lezi zimila zingaphazamisa i- amanyikwe' imisebenzi evamile futhi isabalale kwezinye izingxenye zomzimba.Izinhlobo Zomdlavuza WamanyikweUhlobo oluvame kakhulu umdlavuza wamanyikwe i-adenocarcinoma, eqala kusuka kumaseli e-exocrine akhiqiza ama-enzyme okugaya. Ezinye, izinhlobo ezingajwayelekile kakhulu zihlanganisa: Izimila ze-Neuroendocrine (NETs): Lezi zivela kumaseli e-endocrine akhiqiza amahomoni. I-squamous cell carcinoma I-Adenosquamous carcinoma Izimpawu Zomdlavuza Wamanyikwe Isigaba sokuqala umdlavuza wamanyikwe ngokuvamile akubangeli izimpawu eziphawulekayo. Njengoba isimila sikhula, izimpawu zingase zihlanganise: Ubuhlungu besisu (ngokuvamile obuphumela emhlane) Ijaundice (ukuba phuzi kwesikhumba namehlo) Ukuncipha kwesisindo Ukulahlekelwa ukudla Isicanucanu nokuhlanza Izinguquko ezindleleni zamathumbu Isifo sikashukela esisanda kuqala noma ubunzima bokulawula isifo sikashukela esikhona UkukhathalaUma uhlangabezana nanoma iyiphi yalezi zimpawu, ikakhulukazi uma ziqhubeka njalo noma zibalulekile ukuze zigwenywe udokotela. Khumbula, lezi zimpawu zingabangelwa ezinye izimo, kodwa ukuxilongwa ngokushesha kubalulekile.Izinto Eziyingozi Zomdlavuza WamanyikweNakuba imbangela yangempela umdlavuza wamanyikwe akuqondwa ngokugcwele, kuye kwatholakala izici eziningana eziyingozi: Ukubhema: Ababhemayo banamathuba aphindwe kabili noma kathathu okuba bathuthuke. umdlavuza wamanyikwe kunabangabhemi. Ukukhuluphala ngokweqile: Ukukhuluphala ngokweqile noma ukukhuluphala ngokweqile kwandisa ingozi. Isifo sikashukela: Abantu abanesifo sikashukela, ikakhulukazi uhlobo 2, basengozini enkulu. I-pancreatitis engapheli: ukuvuvukala okuhlala isikhathi eside amanyikwe kuyisici esiyingozi. Umlando womndeni: Ukuba nomlando womndeni we umdlavuza wamanyikwe noma ama-syndromes athile ofuzo anyusa ubungozi. Iminyaka yobudala: Ingozi iyanda ngokuya ngeminyaka, futhi izimo eziningi zitholwa ngemva kweminyaka yobudala engama-65. Uhlanga: Abantu base-Afrika baseMelika banengozi ephakeme kancane kunamanye amaqembu ezinhlanga. Ukunciphisa izinto eziyingozi eziguquguqukayo, njengokubhema nokugcina isisindo esinempilo, kungasiza ekunciphiseni ingozi yokuthuthukisa umdlavuza wamanyikwe.Ukuxilongwa Komdlavuza WamanyikweUkuxilonga umdlavuza wamanyikwe ngokuvamile ihlanganisa inhlanganisela yalokhu okulandelayo: Ukuhlolwa komzimba nomlando wezokwelapha: Udokotela uzobuza mayelana nezimpawu zakho, izici eziyingozi, nomlando wezokwelapha. Ukuhlolwa kwesithombe: I-CT scan: Inikeza izithombe ezinemininingwane ye- amanyikwe nezitho ezizungezile. I-MRI: Isebenzisa amandla kazibuthe namagagasi omsakazo ukwenza izithombe amanyikwe. I-Endoscopic ultrasound (EUS): Isebenzisa i-endoscope ene-ultrasound probe ukuze ubone ngeso lengqondo amanyikwe futhi uthole amasampula ezicubu. I-Biopsy: Isampula yethishu ithathwa ku amanyikwe futhi ihlolwe ngaphansi kwesibonakhulu ukuze kuqinisekiswe ukuba khona kwamangqamuzana omdlavuza. Lokhu kungenziwa ngesikhathi se-EUS noma ngezinye izinqubo. Ukuhlolwa kwegazi: Ukuhlolwa kwegazi kungasiza ukuhlola ukusebenza kwesibindi nokukhomba izimpawu zesimila, njenge-CA 19-9.Staging of Pancreas CancerOnce umdlavuza wamanyikwe uma kutholakala ukuthi umdlavuza usabalele kangakanani. Ukwenza isiteji kusiza odokotela bahlele ukwelashwa okufanele kakhulu. Isigaba 0: Amaseli angavamile atholakala olwelweni lwe amanyikwe. Isigaba I: Umdlavuza utholakala kuphela amanyikwe. Isigaba II: Umdlavuza ususabalele ezicutshini nasezithweni eziseduze. Isigaba III: Umdlavuza ususabalele kuma-lymph nodes aseduze. Isigaba IV: Umdlavuza ususabalele ezithweni ezikude, njengesibindi, amaphaphu, noma i-peritoneum.Izinketho Zokwelapha I-Pancreas CancerUkwelashwa umdlavuza wamanyikwe kuncike esigabeni somdlavuza, impilo yesiguli iyonke, nezinye izici. Izinketho zokwelashwa ezijwayelekile zihlanganisa: Ukuhlinzwa: Ukususwa ngokuhlinzwa kwesimila ngokuvamile kuyindlela yokwelapha eyinhloko yesigaba sokuqala umdlavuza wamanyikwe. Uhlobo oluthile lokuhlinzwa luncike endaweni yesimila. Izinqubo zihlanganisa inqubo ye-Whipple (pancreaticoduodenectomy), i-distal pancreatectomy, kanye ne-pancreatectomy ephelele. I-Chemotherapy: I-Chemotherapy isebenzisa izidakamizwa ukubulala amangqamuzana omdlavuza. Ingase isetshenziswe ngaphambi kokuhlinzwa ukuze kuncishiswe isimila, ngemva kokuhlinzwa ukuze kubulawe noma yimaphi amangqamuzana omdlavuza asele, noma njengokwelashwa okuyinhloko kwabathuthukisiwe. umdlavuza wamanyikwe. Izidakamizwa ezivamile ze-chemotherapy zihlanganisa i-gemcitabine, i-nab-paclitaxel, ne-FOLFIRINOX. Ukwelashwa ngemisebe: Ukwelashwa ngemisebe kusebenzisa imisebe enamandla amakhulu ukubulala amangqamuzana omdlavuza. Ingasetshenziswa ngaphambi kokuhlinzwa ukuze kuncishiswe isimila, ngemva kokuhlinzwa ukuze kubulawe noma yimaphi amangqamuzana omdlavuza asele, noma ukukhulula izimpawu zokuthuthuka. umdlavuza wamanyikwe. Ukwelapha okuhlosiwe: Imithi yokwelapha eqondisiwe iqondise kuma-molecule athile abandakanyekayo ekukhuleni kwamangqamuzana omdlavuza nasekuphileni kwawo. Lezi zidakamizwa zivame ukusetshenziswa ngokuhambisana ne-chemotherapy. Izibonelo zifaka ama-EGFR inhibitors nama-PARP inhibitors. I-Immunotherapy: I-Immunotherapy isiza amasosha omzimba ukulwa nomdlavuza. Nakuba kungakabi ukwelashwa okujwayelekile kwazo zonke izinhlobo ze umdlavuza wamanyikwe, libonisa isithembiso ezimweni ezithile. Ukunakekelwa kwe-Palliative: Ukunakekelwa kwe-Palliative kugxile ekudambiseni izimpawu kanye nokwenza ngcono izinga lempilo yeziguli ezithuthukile umdlavuza wamanyikwe. Kungabandakanya ukuphathwa kwezinhlungu, ukwesekwa kokudla okunomsoco, nokusekelwa ngokomzwelo.I-Shandong Baofa Cancer Research Institute: Advancing Pancreas Cancer TreatmentAt I-Shandong Baofa Cancer Research Institute, sizinikele ekuthuthukiseni ukuqonda nokuphathwa kwe umdlavuza wamanyikwe. Ithimba lethu lama-oncologists anolwazi, odokotela abahlinzayo, nabacwaningi lizibophezele ekuhlinzekeni ukunakekelwa komuntu siqu nokusha ezigulini umdlavuza wamanyikwe. Sinikeza izinhlobonhlobo zezinsizakalo, ezihlanganisa: Ukuthwebula okuthuthukisiwe kokuxilonga Izindlela zokuhlinza ezingenele kancane Imithi yomuntu siqu yokwelapha ngamakhemikhali Ukuhlolwa kwemitholampilo yezindlela zokwelapha ezisanda kuzalwa Izinsizakalo zokunakekelwa kwe-palliativeSitholakala eShandong, kodwa siyakwamukela iziguli ezivela emhlabeni wonke. Umgomo wethu uhambisana nokuthola izindlela zokwelapha ezintsha kanye nokunikeza izinketho zeziguli ukuze ziphile isikhathi eside nezimpilo ezinempilo. Izikhungo zethu ezisezingeni lomhlaba kanye nezindlela ezibandakanya imikhakha eminingi ziqinisekisa ukuthi iziguli zethu zithola ukunakekelwa okungcono kakhulu umdlavuza wamanyikwe nezinye izinhlobo zalesi sifo esiyinselele.Ukuphila Nomdlavuza WamanyikweUkuxilongwa kwe umdlavuza wamanyikwe kungaba nzima. Kubalulekile ukufuna ukwesekwa emndenini, kubangani, nakubasebenzi bezempilo. Amaqembu okusekela kanye nemiphakathi eku-inthanethi nayo inganikeza izinsiza ezibalulekile nokuxhumana nabanye ababhekene nezinselele ezifanayo. Ukulawula izimpawu, ukugcina indlela yokuphila enempilo, nokuhlala unolwazi mayelana nezinketho zokwelapha kungasiza ukuthuthukisa izinga lempilo phakathi nangemuva kokwelashwa.I-Prognosis for Pancreas CancerIsibikezelo sokuthi umdlavuza wamanyikwe kuyahlukahluka kuye ngesigaba somdlavuza, impilo yesiguli iyonke, kanye nendlela esisabela ngayo ekwelashweni. Ukutholwa kusenesikhathi kanye nentuthuko ekwelashweni kuthuthukise amazinga okusinda eminyakeni yakamuva. Nokho, umdlavuza wamanyikwe isalokhu iyisifo esiyinselele, futhi ucwaningo oluqhubekayo lubalulekile ekuthuthukiseni amakhambi asebenza ngempumelelo.Intuthuko Yakamuva KuCancer Cancer Research umdlavuza wamanyikwe ilokhu ivela njalo. Ezinye izindawo ezithembisayo zocwaningo zihlanganisa: Imithi emisha yokwelapha ngamakhemikhali nezinhlanganisela Izindlela zokwelapha eziqondisiwe eziqondise ngokuqondile amangqamuzana omdlavuza I-Immunotherapy ethuthukisa amandla amasosha omzimba okulwa nomdlavuza umdlavuza wamanyikwe usaqala Ukuvikela Umdlavuza WamanyikweYize ingekho indlela eqinisekisiwe yokuvimbela umdlavuza wamanyikwe, izinguquko ezithile endleleni yokuphila zingasiza ekunciphiseni ingozi: Yeka ukubhema. Gcina isisindo esinempilo. Yidla ukudla okunempilo okucebile izithelo, imifino, nokusanhlamvu. Nciphisa ukusetshenziswa kotshwala. Phatha isifo sikashukela. Thola ukuhlolwa njalo nodokotela wakho.Lolu lwazi luhloselwe izinjongo zokufundisa kuphela futhi akufanele luthathwe njengeseluleko sezokwelapha. Hlala uthintana nochwepheshe bezempilo abaqeqeshiwe ukuze uxilongwe futhi ulashwe noma yisiphi isimo sezempilo.