ukwelashwa komdlavuza we-squamous cell lung

Ukwelashwa komdlavuza wamaphaphu we-squamous cell izinketho ziyahlukahluka kuye ngesiteji, indawo, kanye nempilo yonke yesiguli. Izindlela zokwelapha ezijwayelekile zihlanganisa ukuhlinzwa, ukwelashwa ngemisebe, i-chemotherapy, ukwelashwa okuhlosiwe, kanye ne-immunotherapy. Ngokuvamile, inhlanganisela yalezi zindlela zokwelapha isetshenziselwa ukuzuza umphumela omuhle kakhulu. E-Shandong Baofa Cancer Research Institute, sihlinzeka ngezinketho zokwelapha ezithuthukisiwe kanye nokunakekelwa komuntu siqu ezigulini ezinakho umdlavuza we-squamous wamaphaphu.Ukuqonda I-Squamous Cell Umdlavuza WamaphaphuUyini Umdlavuza We-Squamous Cell Wamaphaphu?Umdlavuza wamaphaphu we-squamous cell (SCC) wuhlobo lomdlavuza wamaphaphu ongewona omncane (i-NSCLC) osuka kumaseli e-squamous, amangqamuzana amancane, ayisicaba axhume imigudu yomoya yamaphaphu. I-SCC ivame ukuhlotshaniswa nomlando wokubhema futhi ijwayele ukukhula engxenyeni emaphakathi yamaphaphu, eduze kwemigudu yomoya eyinhloko.Izici Zobungozi NezimbangelaIsici esiyinhloko sobungozi umdlavuza we-squamous wamaphaphu uyabhema. Ezinye izici eziyingozi zihlanganisa ukuchayeka entuthuni kagwayi, i-radon, i-asbestos, namanye amakhemikhali. Izakhi zofuzo kanye nomlando womndeni womdlavuza wamaphaphu nakho kungase kwenyuse ingozi.Izimpawu Zomdlavuza Wamaphaphu I-Squamous CellIzimpawu umdlavuza we-squamous wamaphaphu kungahluka kodwa kungase kuhlanganise: Ukukhwehlela okungapheli Ukukhwehlela igazi (i-hemoptysis) Ubuhlungu besifuba Ukuphelelwa umoya Ukuhefuzela Ukwehla kwesisindo okungachazeki Ukukhathala Ukutheleleka okuphindaphindiwe kokuphefumula, njengenyumoniya noma ukucinana kwemigudu yokuphefumula, njengenyumoniya noma ukucinana kwemigudu yokuphefumula. umdlavuza we-squamous wamaphaphu ngokuvamile kubandakanya inhlanganisela yokuhlolwa kwezithombe kanye nama-biopsies.Ukuhlolwa KwezithombeUkuhlola okujwayelekile kwezithombe kufaka phakathi: I-X-ray yesifuba: Ingasiza ekuboneni izixuku ezingavamile emaphashini. I-CT Scan (i-Computed Tomography): Inikeza izithombe ezinemininingwane eminingi yamaphaphu nezicubu ezizungezile. I-PET Scan (i-Positron Emission Tomography): Ingasiza ekutholeni amaseli omdlavuza kuwo wonke umzimba. I-MRI (i-Magnetic Resonance Imaging): Ingase isetshenziselwe ukuhlola izinga lomdlavuza.I-BiopsyA biopsy iyadingeka ukuze kuqinisekiswe ukuxilongwa nokunquma uhlobo lomdlavuza wamaphaphu. Izindlela ze-Biopsy zihlanganisa: I-Bronchoscopy: Ishubhu elincanyana, eligobekayo elinekhamera lifakwa emigwaqweni yomoya ukuze libone ngeso lengqondo futhi liqoqe amasampula ezicubu. I-Needle Biopsy: Inalithi isetshenziselwa ukuqoqa amasampula ezicubu ngodonga lwesifuba. I-Biopsy Yokuhlinzwa: Kwezinye izimo, kungase kudingeke ukuhlinzwa ukuze kutholwe isampula yethishu.Ukwelashwa Komdlavuza wamaphaphu we-Squamous Cell IzinkethoIndlela yokwelapha ye umdlavuza we-squamous wamaphaphu kuncike ezicini eziningana, okuhlanganisa isigaba somdlavuza, impilo yesiguli iyonke, nezinto ezithandwa umuntu siqu. Izinketho zokwelapha ezivamile zihlanganisa ukuhlinzwa, ukwelapha ngemisebe, ukwelapha ngamakhemikhali, ukwelashwa okuhlosiwe, kanye nokwelashwa kwamasosha omzimba.UkuhlinzwaUkuhlinzwa kungase kube inketho uma umdlavuza utholakala endaweni futhi ungasakazekelanga ezindaweni ezikude. Izinqubo zokuhlinza ze umdlavuza we-squamous wamaphaphu zihlanganisa: Ukususwa Kwe-Wedge: Ukususwa kwengxenye encane yephaphu emise okumise okwejiko. I-Segmentectomy: Ukususwa kwengxenye enkulu yephaphu. I-Lobectomy: Ukususwa kwe-lobe yonke yephaphu. I-Pneumonectomy: Ukususwa kwephaphu lonke.Ukwelashwa ngemisebeUkwelashwa ngeRadiation kusebenzisa imishayo enamandla amakhulu ukubulala amangqamuzana omdlavuza. Ingasetshenziswa njengokwelashwa okuyisisekelo, ngaphambi kokuhlinzwa ukuze kuncishiswe isimila, noma ngemva kokuhlinzwa ukubulala noma imaphi amangqamuzana omdlavuza asele. Izinhlobo zokwelashwa ngemisebe zihlanganisa: I-Beam Radiation Therapy yangaphandle (EBRT): Imisebe ihanjiswa emshinini ongaphandle komzimba. I-Brachytherapy: Izinto ezikhipha imisebe zifakwa ngqo ngaphakathi emzimbeni eduze nomdlavuza.I-ChemotherapyUkwelashwa kwemithiUkwelapha usebenzisa imithi ukubulala amangqamuzana omdlavuza kuwo wonke umzimba. Ivame ukusetshenziswa ngokuhambisana nokuhlinzwa noma ukwelashwa ngemisebe. Imithi ejwayelekile ye-chemotherapy ye umdlavuza we-squamous wamaphaphu zihlanganisa i-cisplatin, i-carboplatin, i-paclitaxel, i-docetaxel, ne-gemcitabine.Imithi yokwelapha ehlosiwe ye-TherapyTargeted iqondise ama-molecule athile ahilelekile ekukhuleni kweseli lomdlavuza kanye nokuphila. Lezi zindlela zokwelapha zivame ukusetshenziswa ezigulini ezinezinguquko ezithile zofuzo noma ama-biomarker. Kodwa-ke, izindlela zokwelapha ezihlosiwe zivame ukusetshenziswa kakhulu ku-adenocarcinoma, olunye uhlobo lwe-NSCLC, kune umdlavuza we-squamous wamaphaphu.Imishanguzo ye-Immunotherapy isiza amasosha omzimba ukubona futhi ahlasele amangqamuzana omdlavuza. Lezi zindlela zokwelapha zibonise imiphumela ethembisayo ekwelapheni umdlavuza we-squamous wamaphaphu. Izidakamizwa ezivamile ze-immunotherapy zihlanganisa i-pembrolizumab, i-nivolumab, ne-atezolizumab.Ukwelashwa nge-StageIsigaba somdlavuza sithonya kakhulu uhlelo lokwelapha. Ngezansi umbono jikelele wezinketho zokwelapha ngesiteji. Sicela uxhumane nochwepheshe bezokwelapha abaqeqeshiwe ukuze uthole uhlelo lokwelapha lomuntu siqu. Izinketho Zokwelashwa Kwesiteji Ukuhlinzwa Kwesiteji (i-lobectomy noma i-wedge resection) kulandelwa i-adjuvant chemotherapy kwezinye izimo. Isigaba II Ukuhlinzwa okulandelwa yi-adjuvant chemotherapy. Ukwelashwa ngemisebe kungase kucatshangelwe uma ukuhlinzwa kungeyona inketho. Isigaba III Inhlanganisela ye-chemotherapy kanye ne-radiation therapy. Ukuhlinzwa kungase kucatshangelwe ezimweni ezikhethiwe. I-Immunotherapy ingase ibe inketho ngemva kwe-chemoradiation. I-Stage IV Chemotherapy, i-immunotherapy, ukwelashwa okuhlosiwe (uma kusebenza), ukwelapha ngemisebe ukuphatha izimpawu. Ukunakekelwa kwe-Palliative ukuthuthukisa izinga lempilo. I-Clinical TrialsIzinhlolo zocwaningo ziyizifundo zocwaningo ezihlola izindlela zokwelapha ezintsha umdlavuza we-squamous wamaphaphu. Iziguli zingase zicabange ukubamba iqhaza ezivivinyweni zomtholampilo ukuze zifinyelele ekwelashweni kwesimanjemanje. I-Shandong Baofa Cancer Research Institute ibamba iqhaza ngenkuthalo ezivivinyweni zomtholampilo, ihlinzeka iziguli ukufinyelela entuthukweni yakamuva yokwelashwa komdlavuza.I-Shandong Baofa Cancer Research Institute: Uzakwethu Ekunakekelweni Komdlavuza Wamaphaphu I-Shandong Baofa Cancer Research Institute, sizinikele ekuhlinzekeni ukunakekelwa okuphelele futhi komuntu siqu ezigulini ezine umdlavuza we-squamous wamaphaphu. Ithimba lethu lochwepheshe bemikhakha eminingi lihlanganisa ongoti bezokwelapha, odokotela be-radiation oncologists, odokotela abahlinzayo, nochwepheshe abasekelayo. Sinikeza izinketho ezisezingeni eliphezulu zokuxilonga nokwelashwa, okuhlanganisa ukuhlinza, ukwelapha ngemisebe, ukwelashwa ngamakhemikhali, ukwelashwa okuhlosiwe, i-immunotherapy, nezivivinyo zomtholampilo.Siyaqonda ukuthi ukuhlonzwa komdlavuza kungaba nzima kakhulu. Kungakho sizibophezele ekunikezeni ukunakekelwa kozwelo nokusekela kulo lonke uhambo lwakho lomdlavuza. Xhumana nathi namuhla ukuze ufunde kabanzi mayelana nezinsizakalo zethu nokuthi singakusiza kanjani.Ukuphila Nomdlavuza We-Squamous Cell Lung umdlavuza we-squamous wamaphaphu zingaletha izinselele eziningi. Ukulawula izimpawu, ukubhekana nemiphumela engemihle yokwelashwa, nokubhekana nezidingo ezingokomzwelo nezingokwengqondo konke kuyizici ezibalulekile zokunakekela. Amaqembu okusekela, ukwelulekwa, kanye nezinsizakalo zokunakekela abagulayo zingasiza iziguli nemindeni yazo ukuthi zikwazi ukubhekana nalezi zinselele.Izinsiza kanye NokwesekwaIzinhlangano eziningi zinikeza izinsiza nokusekelwa kwabantu abanomdlavuza wamaphaphu, okuhlanganisa: Inhlangano Yomdlavuza WaseMelika (i-American Cancer Society)www.cancer.org) I-Lung Cancer Research Foundation (www.lungcancerresearchfoundation.orgI-American Lung Association (www.lung.org)IsiphethoUmdlavuza wamaphaphu we-squamous cell kuyisifo esibucayi, kodwa ngokutholwa kusenesikhathi nokwelashwa okufanele, iziguli eziningi zingazuza imiphumela emihle. Ukuqonda izici zobungozi, izimpawu, izindlela zokuxilonga, nezinketho zokwelapha kubalulekile ekuphatheni ngempumelelo. E-Shandong Baofa Cancer Research Institute, sizibophezele ekuhlinzekeni ukunakekelwa kwekhwalithi ephezulu kakhulu ezigulini ezinakho umdlavuza we-squamous wamaphaphu.Umshwana wokuzihlangula: Lesi sihloko sinikeza ulwazi olujwayelekile futhi akufanele kubhekwe njengeseluleko sezokwelapha. Hlala uthintana nochwepheshe bezempilo abaqeqeshiwe ukuze uxilongwe futhi ulashwe izimo zezokwelapha.Izithenjwa: I-American Cancer Society. (n.d.). Uyini Umdlavuza Wamaphaphu? Kubuyiswe kusuka https://www.cancer.org/cancer/lung-cancer/about/what-is-lung-cancer.html I-National Cancer Institute. (n.d.). Ukwelashwa Komdlavuza Wamaphaphu (PDQ?)–Inguqulo Yesiguli. Kubuyiswe kusuka https://www.cancer.gov/types/lung/patient/non-small-cell-lung-treatment-pdq