isigaba 3 Ukwelashwa komdlavuza wamaphaphu ongewona omncane

Isigaba 3 Izinketho Zokwelapha Umdlavuza Wengqamuzana Engasincane Le ndatshana ihlinzeka ngemininingwane ebanzi yezinketho zokwelapha umdlavuza wamaphaphu wengqamuzana ongewona omncane (NSCLC) wesigaba 3, okuhlanganisa ukuhlinzwa, ukwelapha ngamakhemikhali, ukwelapha ngemisebe, ukwelashwa okuhlosiwe, kanye nokwelashwa kwamasosha omzimba. Ihlola intuthuko yakamuva futhi isiza iziguli ukuthi ziqonde izinqumo zazo ngokubonisana nodokotela wazo we-oncologist.

Isigaba 3 Izinketho Zokwelashwa Komdlavuza Wengqamuzana Engancane

Isiteji sesi-3 umdlavuza wamaphaphu ongewona omncane (NSCLC) isifo esibucayi, kodwa intuthuko ku-oncology yezokwelapha inikeza izinketho eziningi zokwelapha. Indlela engcono kakhulu incike ezicini ezihlukahlukene, okuhlanganisa uhlobo oluthile kanye nesigaba somdlavuza, impilo yakho yonke, kanye nezinto ozikhethayo. Le ndatshana ihlose ukukunikeza ukuqonda okucacile kwezindlela zokwelapha ezitholakalayo, kodwa kubalulekile ukukhumbula ukuthi lolu lwazi akufanele luthathe indawo yokubonisana nodokotela wakho we-oncologist. Bazodala uhlelo lokwelapha lomuntu siqu olusekelwe ezimweni zakho ezihlukile.

Ukuqonda Isigaba 3 NSCLC

Isigaba sesi-3 se-NSCLC sihlukaniswe ngezigaba IIIA kanye ne-IIIB, okubonisa izinga lokusabalala komdlavuza. Isigaba IIIA sibandakanya umdlavuza osusabalele kuma-lymph nodes aseduze, kuyilapho i-IIB ihlanganisa ukubandakanyeka okubanzi kwama-lymph node kanye nezitho ezingase zibe eduze. Isiteji esinembile sibalulekile ekunqumeni isu lokwelapha elisebenza kahle kakhulu. Ukuhlolwa kokucabanga okufana nama-CT scan nama-PET scan asetshenziselwa ukukala umdlavuza.

Izindlela Zokwelapha ZeSigaba 3 NSCLC

Ukuhlinzwa

Ukuhlinzwa kungase kube inketho kwezinye iziguli ezinesigaba sesi-3 se-NSCLC, ikakhulukazi lezo ezinesifo sendawo. Uhlobo lokuhlinzwa olwenziwa luncike endaweni kanye nobukhulu besimila. Kungase kuhlanganise ukukhipha isimila kanye nengxenye yephaphu (lobectomy noma i-pneumonectomy) kanye nama-lymph node okungenzeka athinteke. Izinketho zokuhlinza zivame ukuhlolwa ngokusekelwe ezicini ngazinye kumongo wendlela yethimba lemikhakha eminingi. I-Shandong Baofa Cancer Research Institute inikeza ubuchwepheshe obuphelele be-oncology yokuhlinzwa.

I-Chemotherapy

I-Chemotherapy, isebenzisa izidakamizwa ukubulala amangqamuzana omdlavuza, iyindlela yokwelapha eyisisekelo yesigaba sesi-3 umdlavuza wamaphaphu ongewona omncane. Ingase isetshenziswe ngaphambi kokuhlinzwa (i-neoadjuvant chemotherapy) ukuze kuncishiswe isimila, ngemva kokuhlinzwa (i-adjuvant chemotherapy) ukuze kwehliswe ingozi yokuphinda, noma njengokwelashwa okuyinhloko uma ukuhlinzwa kungenzeki. Kunezinhlobo ezahlukene zemithi yokwelapha ngamakhemikhali, futhi ukukhetha kuncike ezintweni ezihlanganisa impilo yesiguli kanye nezici ezithile zesimila.

Ukwelapha Ngemisebe

Ukwelapha ngemisebe kusebenzisa imisebe enamandla amakhulu ukucekela phansi amangqamuzana omdlavuza. Ivame ukusetshenziswa ngokuhambisana ne-chemotherapy esigabeni sesi-3 umdlavuza wamaphaphu ongewona omncane, kanyekanye noma ngokulandelana. Ukwelashwa ngemisebe kungasiza ukunciphisa izimila, kudambise izimpawu, futhi kuthuthukise amazinga okusinda. I-stereotactic body radiation therapy (SBRT) iwuhlobo olunembe kakhulu lokwelapha ngemisebe oluletha imithamo ephezulu yemisebe esimila kuyilapho kunciphisa umonakalo ezicutshini ezinempilo ezizungezile.

Ukwelapha Okuhlosiwe

Izindlela zokwelapha ezihlosiwe ziyimithi eqondise ngokuqondile amangqamuzana omdlavuza ngokusekelwe ekuguquguqukeni kwawo kofuzo. Uma eyakho umdlavuza wamaphaphu ongewona omncane inezinguquko ezithile zofuzo, njengokuguqulwa kwe-EGFR noma ukuhlela kabusha kwe-ALK, ukwelapha okuhlosiwe kungase kube inketho yokwelapha ephumelelayo. Lezi zindlela zokwelapha zinikeza isenzo esiqondiswe kakhulu, okungenzeka sibe nemiphumela engemihle embalwa uma kuqhathaniswa nokwelapha ngamakhemikhali okuvamile. I-Shandong Baofa Cancer Research Institute isebenzisa amasu athuthukile kanye nobuchwepheshe ukuhlola amaphrofayili ofuzo.

I-Immunotherapy

I-Immunotherapy ihlanganisa amasosha omzimba ukulwa nomdlavuza. Izidakamizwa ze-Immunotherapy, njenge-checkpoint inhibitors, zingasiza amasosha omzimba ukubona futhi ahlasele amangqamuzana omdlavuza ngempumelelo. I-Immunotherapy isetshenziswa kakhulu ekwelapheni umdlavuza wamaphaphu ongewona omncane, ngokuvamile ngokuhlanganiswa nezinye izindlela zokwelapha, futhi uye wabonisa isithembiso ekuthuthukiseni imiphumela kwezinye iziguli. Lolu hlobo lokwelapha seluphenduke intuthuko ephawulekayo kubantu abathile beziguli.

Ukukhetha Uhlelo Lokwelapha Olulungile

Uhlelo lokwelapha olungcono kakhulu lwesigaba 3 umdlavuza wamaphaphu ongewona omncane kunqunywa ithimba lezinhlaka eziningi lochwepheshe bezokunakekelwa kwempilo, okuhlanganisa ongoti be-oncologists, odokotela abahlinzayo, odokotela be-radiation oncologists, nabanye ochwepheshe. Bazocubungula ngokucophelela izimo zakho ngazinye, njengempilo yakho iyonke, izinga lokusabalala komdlavuza, kanye nezinto ozikhethayo, ukuze kuthuthukiswe isu lokwelapha elenzelwe wena siqu neliphelele. Ukuxhumana okuvulekile nethimba lakho lezempilo kubalulekile kuyo yonke inqubo yokwelashwa.

Izilingo Zomtholampilo

Ukubamba iqhaza ezivivinyweni zomtholampilo kunganikeza ukufinyelela ekwelapheni okuphambili futhi kube negalelo entuthukweni umdlavuza wamaphaphu ongewona omncane ucwaningo. I-oncologist yakho ingaxoxa ngokuthi ukubamba iqhaza esivivinyweni somtholampilo kungase kukufanele yini.

Umshwana wokuzihlangula: Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi akufanele luthathwe njengeseluleko sezokwelapha. Hlala uthintana nomhlinzeki wakho wokunakekelwa kwezempilo nganoma yikuphi ukukhathazeka ngezempilo noma ngaphambi kokwenza noma yiziphi izinqumo ezihlobene nempilo noma ukwelashwa kwakho.