izimpawu zomdlavuza we-pancreatic

Izimpawu zomdlavuza we-pancreatic ngokuvamile kuhlala kucashile ezigabeni zokuqala, okwenza kube inselele ukutholakala kusenesikhathi. Izimpawu ezivamile zihlanganisa ubuhlungu besisu, ukuncipha kwesisindo esingaqondakali, i-jaundice (isikhumba esiphuzi namehlo), ukushintsha kwemikhuba yamathumbu, nesifo sikashukela esisanda kuqala. Ukuhlolwa ngokushesha kwezokwelapha kubalulekile uma uhlangabezana nanoma yiziphi zalezi zimpawu, njengoba ukuxilonga kusenesikhathi kuyithuthukisa kakhulu imiphumela yokwelashwa. Lesi sihloko sizohlola izimpawu ezihlukahlukene ezihlobene izimpawu zomdlavuza we-pancreatic, izindlela zokuxilonga, kanye nezinketho zokwelapha ezitholakalayo.Ukuqonda Umdlavuza WamanyikweI-pancreas iyisitho esingemuva kwesisu esidlala indima ebalulekile ekugayekeni ukudla nasekulawuleni ushukela egazini. Umdlavuza we-pancreatic kwenzeka lapho amangqamuzana angavamile ekhula ngokungalawuleki kumanyikwe. Kunezinhlobo ezimbili eziyinhloko: izimila ze-exocrine, ezivame kakhulu, kanye nezimila ze-endocrine. I-Adenocarcinoma iwuhlobo oluvame kakhulu lomdlavuza we-exocrine pancreatic. Izimpawu Ezivamile Zomdlavuza WamanyikweUkuqaphela izimpawu kusenesikhathi kungaba nomthelela omkhulu ekwelapheni kanye namazinga okusinda. Nokho, eziningi zalezi zimpawu zingabangelwa ezinye izimo. Ngakho-ke, kubalulekile ukubonana nodokotela ukuze uthole ukuxilongwa okufanele. Ubuhlungu Besisu Ubuhlungu besisu bungenye yezinto ezivame kakhulu izimpawu zomdlavuza we-pancreatic. Imvamisa iqala njengobuhlungu obuthuntu besisu obungase buphume ngemuva. Ubuhlungu bungakhula ngemva kokudla noma lapho ulele.Ukuncipha Kwesisindo OkungachazekiUkuncipha kwesisindo okuphawulekayo nokungachazeki kungenye ephathelene nezimpawu. Lokhu kungase kube ngenxa ye-malabsorption (ama-pancreas angakhiqizi ama-enzyme anele ukuze kugaywe ukudla) noma izinguquko kumetabolism okubangelwa umdlavuza.I-JaundiceJaundice, ebonakala ngokuba phuzi kwesikhumba nokumhlophe kwamehlo, kwenzeka lapho isimila sivimba umgudu wenyongo. Lokhu kuvinjelwa kuvimbela i-bilirubin, into ephuzi ekhiqizwa isibindi, ukuthi ingakhiphi, ibangele ukuthi yakheke emzimbeni.Izinguquko Zemikhuba YamathumbuUkushintsha kwemikhuba yamathumbu, njengokuhuda, ukuqunjelwa, noma indle enamafutha (i-steatorrhea), kungenzeka ngenxa yekhono le-pancreas elikhubazekile lokukhiqiza i-enzyme yokugaya. I-Steatorrhea ibangela indle ephaphathekile, eningi, futhi enuka kabi.Isifo sikashukela Esiqala Ukuvela Umdlavuza we-pancreatic ngezinye izikhathi ungaholela ekukhuleni kwesifo sikashukela esisanda kuqala noma wenze isifo sikashukela esikhona kube nzima ukusilawula. Lokhu kungenxa yokuthi amanyikwe akhiqiza i-insulin, futhi umdlavuza ungaphazamisa lo msebenzi.Ezinye Izimpawu Ezingaba Khona Isicanucanu nokuhlanza Ukulahlekelwa ukudla Ukukhathala Amahlule egazi Ukukhuliswa kwenyongo noma isibindi Izinto Eziyingozi Zomdlavuza WendlalaIzici eziningana zingandisa ingozi yokuba nomdlavuza. izimpawu zomdlavuza we-pancreatic. Lokhu kufaka phakathi: Ukubhema Ukukhuluphala Isifo sikashukela I-pancreatitis engapheli Umlando womndeni onomdlavuza we-pancreatic Izifo ezithile zofuzo, njenge-BRCA2, i-Peutz-Jeghers syndrome, ne-Lynch syndrome. Iminyaka yobudala: Ingozi iyanda ngokukhula, ngokuvamile okwenzeka ngemva kweminyaka engama-45. izimpawu zomdlavuza we-pancreatic kusolwa, udokotela uzokwenza ukuhlolwa okuphelele ngokomzimba futhi ahlele ukuhlolwa okuhlukahlukene kokuxilonga. Lokhu kuhlola kungasiza ekutholeni ukuthi umdlavuza ukhona yini, isigaba sawo, nokuthi ususabalele yini.Imaging Tests I-Computed Tomography (CT) Scan: I-CT scan isebenzisa ama-X-ray ukuze idale izithombe ezinemininingwane yamanyikwe nezitho ezizungezile. I-Magnetic Resonance Imaging (MRI): I-MRI isebenzisa amandla kazibuthe namaza omsakazo ukuze ikhiqize izithombe ezinemininingwane yamanyikwe. I-Endoscopic Ultrasound (EUS): I-EUS ihilela ukufaka ishubhu elincanyana, eligobekayo eline-ultrasound probe emmizweni nasesiswini ukuze uthole izithombe eziseduze zamanyikwe. Le nqubo ingasetshenziswa futhi ukuthola isampula yethishu ye-biopsy. I-Positron Emission Tomography (PET) Scan: Ngokuvamile kuhlanganiswe ne-CT scan, ukuhlola kwe-PET kungasiza ekutholeni amangqamuzana omdlavuza okungenzeka angabonakali kwezinye izivivinyo zezithombe.I-BiopsyA biopsy ihilela ukuthatha isampula lethishu elincane kumanyikwe ukuze lihlolwe ngaphansi kwesibonakhulu. Lena ukuphela kwendlela yokuxilonga ngokuqinisekile izimpawu zomdlavuza we-pancreatic. Ama-Biopsies angatholwa ngesikhathi se-EUS, ukuhlinzwa, noma nge-biopsy yenaliti eqondiswa yi-imaging.Ukuhlolwa Kwegazi Ukuhlolwa kwegazi, okufana nokuhlolwa kwe-CA 19-9 tumor marker, kungasiza ekutholeni izinto ezikhishwe amangqamuzana omdlavuza. Kodwa-ke, lezi zivivinyo azinembile ngaso sonke isikhathi futhi zivame ukusetshenziswa kanye nezinye izindlela zokuxilonga.Izinketho Zokwelapha I-Pancreatic CancerUkwelashwa izimpawu zomdlavuza we-pancreatic kuncike esiteji nendawo umdlavuza, kanye nempilo jikelele yesiguli. Izinketho zokwelapha ezivamile zihlanganisa:UkuhlinzwaUkuhlinzwa kuvame ukuba yindlela yokwelapha eyinhloko yomdlavuza wamabele, ikakhulukazi uma umdlavuza utholakala endaweni futhi ungasakazeki. Inqubo ye-Whipple (pancreaticoduodenectomy) ukuhlinzwa okuvamile kwamathumba atholakala ekhanda le-pancreas. Ezinye izinketho zokuhlinzwa zihlanganisa i-distal pancreatectomy (ukususwa komsila we-pancreas) kanye ne-pancreatectomy isiyonke (ukususwa kwawo wonke amanyikwe).I-ChemotherapyI-Chemotherapy isebenzisa izidakamizwa ukubulala amangqamuzana omdlavuza. Ingasetshenziswa ngaphambi kokuhlinzwa ukuze kuncishiswe isimila, ngemva kokuhlinzwa ukuze kubulawe noma yimaphi amangqamuzana omdlavuza asele, noma njengokwelashwa okuyinhloko komdlavuza we-pancreatic othuthukisiwe. Imithi ejwayelekile yokwelapha ngamakhemikhali esetshenziselwa ukwelapha umdlavuza we-pancreatic ihlanganisa i-gemcitabine, i-paclitaxel, ne-cisplatin.Ukwelashwa ngemisebeUkwelashwa kweRadiation kusebenzisa imishayo enamandla amakhulu ukubulala amangqamuzana omdlavuza. Ingasetshenziswa yodwa noma ihlanganiswe ne-chemotherapy, ngaphambi noma ngemva kokuhlinzwa. I-Stereotactic body radiation therapy (SBRT) iwuhlobo lokwelapha ngemisebe oluletha imithamo ephezulu yemisebe endaweni enembile.I-Targeted TherapyTargeted therapy isebenzisa imithi eqondise ama-molecule athile abandakanyekayo ekukhuleni kwamangqamuzana omdlavuza. Izibonelo zihlanganisa izidakamizwa eziqondise indlela ye-EGFR noma i-PARP inhibitors ezigulini ezinezinguquko ze-BRCA.I-ImmunotherapyImmunotherapy isebenzisa amasosha omzimba ukulwa nomdlavuza. Nakuba kungavamile ukusetshenziselwa umdlavuza we-pancreatic njengezinye izinhlobo zomdlavuza, i-immunotherapy ingase ibe inketho kwezinye iziguli ezinofuzo oluthile. izimpawu zomdlavuza we-pancreatic. Lokhu kungabandakanya ukuphathwa kobuhlungu, ukwesekwa kokudla okunomsoco, nokwelulekwa ngokomzwelo. I-Shandong Baofa Cancer Research Institute inikeza izinsiza ezibanzi zokunakekelwa kwe-palliative ukusiza iziguli zilawule izimpawu zazo futhi zithuthukise inhlalakahle yazo iyonke. Indlela yesibhedlela i-Baofa yokunakekelwa komdlavuza ihlanganisa izindlela zokwelapha ezisezingeni eliphezulu nezokwelapha ezisekelayo ukuze kuqinisekiswe ukuthi iziguli zithola ukunakekelwa okuphelele nokuqondene nomuntu uqobo. izimpawu zomdlavuza we-pancreatic kuyahlukahluka kuye ngesigaba sokuxilongwa, impilo yesiguli iyonke, kanye nokwelashwa okutholiwe. Ukutholwa kusenesikhathi nokwelashwa kuthuthukisa kakhulu amazinga okusinda. Izinga leminyaka emihlanu lokusinda komdlavuza wasendaweni wasendaweni liphezulu kakhulu kunezigaba ezithuthukile. Ngokusho kwe-American Cancer Society, izinga lokusinda leminyaka emihlanu lazo zonke izigaba zomdlavuza we-pancreatic licishe libe yi-11%. Nokho, lezi zinombolo ziyizilinganiso futhi zingahluka kakhulu kumuntu nomuntu. [1]Nali ithebula elifingqa amanani okusinda ngesiteji, ngokusho kwe-American Cancer Society. Sicela uqaphele ukuthi lezi izilinganiso ezivamile futhi imiphumela ngayinye ingase yehluke. Isigaba Seminyaka Emihlanu Yokusinda Kwezinga Lokutholakala Kwasendaweni (Kuvalelwe Kumanyikwe) I-44% Yesifunda (Sabalalisa Kuzicubu Eziseduze noma Ama-Lymph Nodes) 16% Ekude (Sabalalisa Ezithweni Ezikude) 3% Zonke Izigaba Zihlanganiswe 11% Ukuvimbela Nokutholwa Kwangaphambi Kwalapho ingekho indlela eqinisekisiwe yokuvimbela umdlavuza we-pancreas. Lokhu kuhlanganisa: Ukuyeka ukubhema Ukugcina isisindo esinempilo Ukudla ukudla okulinganiselayo okucebile izithelo nemifino Ukulawula isifo sikashukela Ukunciphisa ukuphuza utshwala Ukuhlolwa njalo nodokotela kubalulekile ukuze usheshe utholakale, ikakhulukazi kubantu abasengozini yokugula. izimpawu zomdlavuza we-pancreatic. Uma uhlangabezana nanoma yiziphi izimpawu, funa usizo lwezokwelapha ngokushesha.Ukuzihlangula: Le ndatshana ihlinzeka ngolwazi olujwayelekile mayelana nezimpawu zomdlavuza we-pancreatic kanye nokwelashwa futhi akufanele kubhekwe njengeseluleko sezokwelapha. Hlala uthintana nochwepheshe bezokunakekelwa kwempilo ukuze uthole isiqondiso somuntu siqu sezokwelapha.1 Umthombo: I-American Cancer Society. 'Amazinga Okusinda Kumdlavuza We-pancreatic'. https://www.cancer.org/cancer/types/pancreatic-cancer/detection-diagnosis-staging/survival-rates.html (Kufinyelelwe ku-Okthoba 26, 2023).