ukwelashwa kwezimpawu zomdlavuza we-pancreatic

Ukuhlonza i ukwelashwa kwezimpawu zomdlavuza we-pancreatic kusenesikhathi kungasithuthukisa kakhulu i-prognosis. Lesi sihloko sicubungula izimpawu ezivamile, izindlela zokuxilonga, kanye nokwelashwa okutholakalayo komdlavuza we-pancreatic, kugcizelela ukubaluleka kokungenelela kwezokwelapha okufika ngesikhathi. Ukuqonda lezi zici kunganikeza abantu amandla okuthola iseluleko sezokwelapha ngokushesha futhi bahambe ohambweni lwabo lokwelashwa ngokuphumelelayo.Ukuqonda Umdlavuza WepancreaticUmdlavuza we-pancreatic kwenzeka lapho amangqamuzana abulalayo akheka ezicutshini ze-pancreas, isitho esingemuva kwesisu. Amanyikwe akhiqiza ama-enzyme asiza ukugaya namahomoni asiza ukulawula ushukela wegazi. Kunezinhlobo ezimbili eziyinhloko zomdlavuza we-pancreatic: i-adenocarcinoma (uhlobo oluvame kakhulu, oluvela kumangqamuzana e-exocrine) kanye nezimila ze-neuroendocrine (ezingavamile kakhulu futhi zivela kumangqamuzana e-endocrine) .Izici Eziyingozi Zomdlavuza We-pancreaticIzici eziningana zingandisa ingozi yokuba nomdlavuza we-pancreatic, okuhlanganisa: Ukubhema: Ababhemayo banamathuba amabili noma amathathu okuba nomdlavuza we-pancreatic izikhathi ezimbili kuya kwezintathu. Ukukhuluphala ngokweqile: Ukukhuluphala ngokweqile noma ukukhuluphala ngokweqile kwandisa ingozi. Isifo sikashukela: Isifo sikashukela esinesikhathi eside siyingozi. I-Pancreatitis Engapheli: Ukuvuvukala kwamanyikwe isikhathi eside kungandisa ingozi. Umlando Womndeni: Ukuba nomlando womndeni womdlavuza we-pancreatic, noma ama-syndromes athile ofuzo, kuphakamisa ingozi. Iminyaka yobudala: Ingozi iyanda ngokuya ngeminyaka, futhi izimo eziningi zenzeka kubantu abangaphezu kweminyaka engama-65.Okuvamile Ukwelashwa Izimpawu Zomdlavuza We-pancreatic kanye ne-SymptomsEarly-stage pancreatic cancer ngokuvamile uveza izimpawu ezimbalwa noma ezingenazo nhlobo, ezingenza ukusheshe kutholakale kube inselele. Njengoba umdlavuza uqhubeka, izimpawu zingase zibe khona. Kubalulekile ukuthi uxhumane nochwepheshe bezempilo uma uhlangabezana nanoma yikuphi kwalokhu okulandelayo ukwelashwa kwezimpawu zomdlavuza we-pancreatic ngokuqhubekayo:I-JaundiceIjaundice, ukuba phuzi kwesikhumba nokumhlophe kwamehlo, kuwuphawu oluvamile. Kwenzeka lapho isimila sivimba i-bile duct, ivimbela i-bile ukuthi ingagelezi kahle. Lokhu kunqwabelana kwe-bilirubin (i-bile pigment) kubangela ukuguquguquka kombala ophuzi.Ubuhlungu BesisuUbuhlungu besisu esingenhla noma emhlane kungolunye uphawu oluvamile. Ubuhlungu bungase bufike futhi budlule, noma buhlale njalo. Kuvame ukuchazwa njengezinhlungu ezibuhlungu, kodwa futhi zingaba bukhali futhi zibe namandla.Ukunciphisa Isisindo Nokulahlekelwa Isifiso Sokudla Ukuncipha kwesisindo okungachazwanga kanye nokuncipha kwesifiso sokudla kuvamile. Umdlavuza we-pancreatic ungaphazamisa ikhono lomzimba lokugaya ukudla kanye nokumunca izakhi, okuholela ekwehleni kwesisindo ngisho nalapho udla ngokujwayelekile.Izinkinga Zokugaya Izinkinga zokugaya ukudla, njengokucanuzela kwenhliziyo, ukuhlanza, nokushintsha kwemikhuba yamathumbu (isb., isifo sohudo noma ukuqunjelwa), kungenzeka. Umdlavuza we-pancreatic ungaphazamisa ukukhiqizwa kwama-enzyme okugaya ukudla, okuholela kulezi zinkinga.Umchamo Omnyama kanye Nendle Enemibala EkhanyayoLezi zinguquko zingabonisa ukuvaleka kwe-bile duct. Umchamo omnyama uwuphawu lwe-bilirubin eyeqile, kuyilapho indle enombala okhanyayo ivela ngenxa yokuthi i-bile ayikhishelwanga kahle.Isifo Sikashukela Esisanda KuqalaEzimeni ezingavamile, umdlavuza wama-pancreas ungabangela isifo sikashukela esisanda kuqala, ikakhulukazi kubantu abadala. Lokhu kungenxa yokuthi isimila singathinta amangqamuzana akhiqiza i-insulini kumanyikwe.Ukuxilongwa KweCancer YepancreaUma uba nezimpawu ezisikisela umdlavuza we-pancreatic, udokotela wakho angase atuse lokhu kuhlolwa kokuxilonga okulandelayo: Ukuhlolwa Komzimba: Ukuhlolwa okuphelele komzimba kuyisinyathelo sokuqala. Ukuhlolwa Kwegazi: Ukuhlolwa kwegazi kungahlola ukusebenza kwesibindi, amazinga e-bilirubin, kanye nokuba khona kwezimpawu zesimila (ezifana ne-CA 19-9). Ukuhlolwa Kwezithombe: I-CT Scan: Izikena ze-Computed tomography (CT) zinikeza izithombe ezinemininingwane yamanyikwe nezitho ezizungezile. I-MRI: I-Magnetic resonance imaging (MRI) ingasiza ekutholeni amathumba futhi ihlole ubukhulu bawo nendawo. I-Endoscopic Ultrasound (EUS): I-EUS ihilela ukufaka ishubhu elincanyana, eliguquguqukayo eline-ultrasound probe phansi kommizo liye esiswini kanye ne-duodenum ukuze ubone amanyikwe ngeso lengqondo. Le nqubo ingasetshenziswa futhi ukuthola amasampula ezicubu ze-biopsy. I-Biopsy: I-biopsy ihilela ukuthatha isampula yethishu encane ukuze ihlolwe nge-microscopic. Lena ukuphela kwendlela yokuqinisekisa ukuhlonzwa komdlavuza we-pancreatic.Izinketho Zokwelapha I-Pancreatic CancerUkwelashwa komdlavuza we-pancreatic kuncike esigabeni nendawo umdlavuza, kanye nempilo jikelele yesiguli. Izinketho zingabandakanya:UkuhlinzwaUkuhlinzwa ukuze kukhishwe isimila kuyindlela yokwelapha eyinhloko yomdlavuza we-pancreatic otholakala endaweni futhi ongasakazekelanga ezindaweni ezikude. Inqubo yokuhlinzwa evame kakhulu inqubo ye-Whipple (pancreaticoduodenectomy), ehilela ukukhipha ikhanda le-pancreas, ingxenye yamathumbu amancane, i-gallbladder, nengxenye yesisu. Ukuhlinzwa okwenziwa ezikhungweni ezifana ne I-Shandong Baofa Cancer Research Institute ngokuvamile ibona imiphumela engcono yesiguli.I-ChemotherapyI-Chemotherapy ihlanganisa ukusebenzisa izidakamizwa ukuze kubulawe amangqamuzana omdlavuza. Ingase isetshenziswe ngaphambi kokuhlinzwa (i-neoadjuvant chemotherapy), ngemva kokuhlinzwa (i-adjuvant chemotherapy), noma njengendlela yokwelapha eyinhloko yomdlavuza we-pancreatic othuthukisiwe.I-Radiation TherapyRadiation therapy isebenzisa imisebe enamandla amakhulu ukubulala amangqamuzana omdlavuza. Ingase isetshenziselwe ukuhlanganiswa nokwelashwa ngamakhemikhali noma njengendlela yokwelapha yokudambisa izimpawu. Le mithi ingase isetshenziswe ezigulini ezinokuguqulwa okuthile kofuzo.I-ImmunotherapyImmunotherapy isiza amasosha omzimba ukubona futhi ahlasele amangqamuzana omdlavuza. Akuvamile ukusetshenziselwa umdlavuza we-pancreatic kodwa kungase kube inketho ezimweni ezithile.Ukunakekelwa kwePalliativeUkunakekelwa kwePalliative kugxile ekudambiseni izimpawu kanye nokwenza ngcono izinga lempilo yeziguli ezinomdlavuza we-pancreatic othuthukile. Lokhu kungase kuhlanganise ukulawula izinhlungu, ukwesekwa ngokudla okunomsoco, nokusekelwa ngokomzwelo.Ukuphila Nomdlavuza WamanyikweUkuphila nomdlavuza wamanyikwe kungaba inselele, ngokomzimba nangokomzwelo. Amaqembu okusekelana, ukwelulekwa, kanye nezinye izinsiza kungasiza iziguli nemindeni yazo ukuba zibhekane nesifo. Ukuqaphela amandla ukwelashwa kwezimpawu zomdlavuza we-pancreatic kanye nokufuna usizo lwezokwelapha ngokushesha kungenza umehluko omkhulu. I I-Shandong Baofa Cancer Research Institute izinikele ekuthuthukiseni ucwaningo lomdlavuza kanye nokuhlinzeka ukunakekelwa okuphelele ezigulini.