maʻemaʻe cell renal cell carcinoma

Clear Cell Renal Cell Carcinoma: He alakaʻi piha ka hoʻomaopopo ʻana i ka maʻi maʻi maʻi maʻi.maʻemaʻe cell renal cell carcinoma), e kālele ana i nā kumu, nā hōʻailona, ​​ka hōʻoia, ka mālama ʻana, a me ka wānana. Manaʻo mākou e hoʻoikaika i ka poʻe me ka ʻike e hoʻokele pono i kēia kūlana paʻakikī. No ka hoʻonaʻauao wale nō ka ʻike i hāʻawi ʻia ma ʻaneʻi a ʻaʻole pono e manaʻo ʻia he ʻōlelo aʻoaʻo olakino. E kūkākūkā mau me kāu mea mālama ola no ka ʻike a me ka mālama ʻana.

Ka hoomaopopo ana i na kumu o Hoʻomaʻemaʻe i ka maʻi maʻi kino kino

He aha ka Hoʻomaʻemaʻe i ka maʻi maʻi kino kino?

Maʻemaʻe cell renal cell carcinoma (ccRCC) ʻo ia ke ʻano maʻamau o ka maʻi maʻi ʻaʻai. Loaʻa ia mai loko mai o nā tubules renal, nā paipu liʻiliʻi i loko o nā puʻupaʻa e kānana i ka ʻōpala mai ke koko. ʻO ka hoʻohālikelike ʻana o ke kelepona maʻemaʻe mai ka ʻike ʻia ʻana o nā pūnana maʻi maʻi ma lalo o kahi microscope - ʻike ʻia lākou i ka akaka a i ʻole translucent ma muli o ka nui o ka glycogen content.

Nā kumu o Hoʻomaʻemaʻe i ka maʻi maʻi kino kino

ʻO ke kumu kūpono o maʻemaʻe cell renal cell carcinoma ʻAʻole ʻike ʻia, akā ua ʻike ʻia kekahi mau mea pilikia: Puhi: Hoʻonui nui ka paka i ka pilikia o ka ulu ʻana maʻemaʻe cell renal cell carcinoma. Nā Kuleana Genetic: ʻO kekahi mau maʻi hoʻoilina hoʻoilina, e like me ka maʻi von Hippel-Lindau (VHL), hoʻonui i ka maʻalahi. Obesity: Hōʻike nā haʻawina i ka pilina ma waena o ka momona a me ka piʻi nui ʻana. Ka ʻike ʻana i kekahi mau mea kemika: Ua hoʻopili ʻia ka ʻike lōʻihi ʻana i kekahi mau kemika ma ka wahi hana i kahi pilikia kiʻekiʻe. Moʻolelo ʻohana: ʻO ka loaʻa ʻana o ka moʻolelo ʻohana o ka maʻi maʻi maʻi ʻaʻai hiki ke hoʻonui i kou pilikia.

Nā hōʻailona o Hoʻomaʻemaʻe i ka maʻi maʻi kino kino

ʻAkahi-pae maʻemaʻe cell renal cell carcinoma ʻike pinepine ʻia me nā hōʻailona ʻike ʻole. I ka ulu ʻana o ka maʻi koko, hiki ke komo i nā hōʻailona: Koko i loko o ka mimi (hematuria) ʻEha ma ka ʻaoʻao (ʻeha ma ka ʻaoʻao).

ʻIke a me ke kau ʻana o Hoʻomaʻemaʻe i ka maʻi maʻi kino kino

Nā hoʻāʻo diagnostic

Ka hoʻopaʻa ʻana maʻemaʻe cell renal cell carcinoma ʻO ka mea maʻamau e pili ana: Nā hoʻāʻo kiʻi: Hoʻohana ʻia nā scan tomography (CT), magnetic resonance imaging (MRI), a me ka ultrasound e nānā i ka ʻōpū a nānā i kona nui a me kona wahi. Biopsy: Wehe ʻia kahi ʻāpana liʻiliʻi o ka ʻiʻo a nānā ʻia ma lalo o kahi microscope e hōʻoia i ka ʻike a hoʻoholo i ke ʻano o ke kanesa.

ʻO ke kau ʻana o Hoʻomaʻemaʻe i ka maʻi maʻi kino kino

Hiki ke hoʻoholo i ka nui o ke kanesa. Hoʻohana mau ʻia ka ʻōnaehana staging TNM, ka hoʻokaʻawale ʻana i ka ʻōpū (T), nā ʻōpū lymph āpau (N), a me ka metastasis mamao (M). Ke alakaʻi nei kēia ʻike i nā hoʻoholo lapaʻau.

Nā koho lapaʻau no Hoʻomaʻemaʻe i ka maʻi maʻi kino kino

Nā koho lapaʻau no maʻemaʻe cell renal cell carcinoma ʻokoʻa ma muli o kekahi mau kumu, e like me ka pae o ka maʻi kanesa, ke olakino holoʻokoʻa o ka mea maʻi, a me nā makemake pilikino. ʻO nā ala lapaʻau maʻamau: ʻO ka ʻoki ʻana: ʻO ka wehe ʻana i ke koko, ʻo ka ʻāpana (nephron-sparing surgery) a i ʻole piha (radical nephrectomy), ʻo ia ka lāʻau mua loa no ka maʻi kūloko. Hoʻohana ʻia nā lāʻau lapaʻau e hoʻopaʻa i nā protein kikoʻī e pili ana i ka ulu ʻana o ka maʻi maʻi maʻi i hoʻohana ʻia no ka mālama ʻana i ka holomua a i ʻole ka metastatic maʻemaʻe cell renal cell carcinoma. ʻO nā laʻana he sunitinib, sorafenib, a me pazopanib. Immunotherapy: Hoʻohana kēia lāʻau lapaʻau i ka ʻōnaehana pale o ke kino e hakakā ai i nā maʻi maʻi maʻi. Hoʻohana ʻia nā mea hoʻopaʻapaʻa checkpoint, e like me nivolumab a me ipilimumab, i kekahi mau hihia. Radiation Therapy: ʻAʻole maʻamau ka lāʻau lapaʻau ka lapaʻau mua no maʻemaʻe cell renal cell carcinoma, akā hiki ke hoʻohana ʻia i nā kūlana kūikawā, e like me ka mālama palliative e mālama i ka ʻeha a i ʻole nā ​​hōʻailona ʻē aʻe. Chemotherapy: ʻAʻole ʻoi aku ka maikaʻi o ka chemotherapy ma mua o ka lāʻau lapaʻau i kuhikuhi ʻia a i ʻole immunotherapy no maʻemaʻe cell renal cell carcinoma a emi iki ka hoʻohana ʻana.

Ka wānana a me ka hoʻokele wā lōʻihi

ʻO ka wānana no maʻemaʻe cell renal cell carcinoma hilinaʻi nui ma ke kahua ma ka hōʻoia a me ke olakino holoʻokoʻa o ka mea maʻi. ʻO ka ʻike mua ʻana a me ka hoʻomaʻamaʻa wikiwiki ʻana e hoʻomaikaʻi nui i ka manawa o ka hopena kūleʻa. Hoʻokomo pinepine ka hoʻokele wā lōʻihi i nā koho maʻamau, nā hoʻokolohua kiʻi, a me ka nānā ʻana no ka hoʻi hou ʻana.

ʻAno Lapaʻau	Nā pono	Nā pōʻino
ʻO ka ʻoki ʻana	He lāʻau lapaʻau no ka maʻi kūloko	Loaʻa paha nā pilikia, ʻaʻole kūpono i nā pae āpau
ʻO ka Lapaʻau Kūlohelohe	Pono no ka ma'i holomua, hiki ke hooloihi i ke ola	Hiki ke nui nā hopena ʻaoʻao
Immunotherapy	Hiki ke alakaʻi i nā pane paʻa i kekahi mau maʻi	Hiki ke loaʻa nā hopena pili pili i ka immune

No ka ʻike hou aku a me ke kākoʻo, e noʻonoʻo e kelepona i ka Shandong Baofa Cancer Research Institute a i ʻole nā kikowaena maʻi maʻi kaulana ʻē aʻe. E hoʻomanaʻo, he mea koʻikoʻi ka ʻike mua ʻana a me ke ʻano o ka mālama ʻana i ka mālama ʻana maʻemaʻe cell renal cell carcinoma. No ka hoʻonaʻauao wale nō kēia ʻike a ʻaʻole ia he ʻōlelo aʻo lapaʻau. E ʻoluʻolu e kamaʻilio me kāu mea mālama ola no kekahi pilikia olakino.