lāʻau lapaʻau lapaʻau maʻi ʻaʻai māmā

Nā Laʻau Lapaʻau Lapaʻau ʻana i ka Maʻi Maʻi ʻĀkau: He alakaʻi piha ʻO ka maʻi maʻi maʻi maʻi maʻi he maʻi koʻikoʻi, a me ka hoʻomaopopo ʻana i ka loaʻa lāʻau lapaʻau lapaʻau maʻi ʻaʻai māmā he mea koʻikoʻi no nā maʻi a me ko lākou ʻohana. Hāʻawi kēia alakaʻi i kahi hiʻohiʻona o nā koho lapaʻau like ʻole, e kālele ana i nā lāʻau i hoʻohana ʻia a me kā lākou hana. E ʻimi mākou i nā ʻano lāʻau lapaʻau like ʻole a hōʻike i ke koʻikoʻi o nā hoʻolālā lapaʻau pilikino i kūpono i nā pono o kēlā me kēia maʻi. No ka hoʻonaʻauao wale nō kēia ʻike a ʻaʻole pono e hoʻololi i ka ʻōlelo aʻoaʻo lapaʻau ʻoihana. E kūkākūkā mau me kāu kauka oncologist a i ʻole mea mālama ola no ka maʻi ʻana a me ka hoʻolālā ʻana.

Nā ʻano o nā lāʻau lapaʻau maʻi maʻi ʻāʻī

ʻO ka Lapaʻau Kūlohelohe

ʻO nā lāʻau lapaʻau i hoʻopaʻa ʻia e kālele ana i nā molekole kikoʻī i loko o nā maʻi kanesa e hoʻoikaika i ko lākou ulu a ola. He ʻokoʻa ka hana o kēia mau lāʻau lapaʻau ma mua o ka chemotherapy maʻamau, me ka manaʻo e hōʻemi i ka pōʻino i nā cell olakino. ʻO nā laʻana o nā lāʻau lapaʻau i hoʻopaʻa ʻia e like me: EGFR inhibitors: Hoʻopili kēia mau lāʻau i ka epidermal growth factor receptor (EGFR), he protein e pāʻani ana i ka ulu ʻana o ke kelepona. He kūpono loa lākou i nā maʻi me nā hoʻololi EGFR. ʻO nā laʻana maʻamau ka gefitinib, erlotinib, a me afatinib. ʻOkoʻa ka hopena a me nā hopena ʻaoʻao mai kēlā me kēia maʻi. ALK inhibitors: ʻO Anaplastic lymphoma kinase (ALK) kekahi pūmua ʻē aʻe e hiki ke kōkua i ka ulu ʻana o ka maʻi kanesa. ʻO nā mea pale ALK, e like me crizotinib, alectinib, a me ceritinib, e kuhikuhi i kēia protein. ʻO nā lāʻau lapaʻau ʻē aʻe i hoʻopaʻa ʻia: Nui nā lāʻau lapaʻau ʻē aʻe i loaʻa, e huli ana i nā molekele like ʻole a me nā ala e pili ana i ka ulu ʻana o ka maʻi kanesa. E hoʻoholo kāu kauka oncologist i ka lapaʻau kūpono loa e pili ana i kāu mau hiʻohiʻona kikoʻī.

Kemoterapi

Hoʻohana ʻo Chemotherapy i nā lāʻau lapaʻau e pepehi i nā maʻi kanesa. Hoʻohana pinepine ʻia kēia mau lāʻau lapaʻau i hui pū ʻia me nā lāʻau lapaʻau ʻē aʻe a hiki ke hāʻawi ʻia i loko o ke koko a i ʻole ka waha. ʻO nā lāʻau lapaʻau chemotherapy maʻamau i hoʻohana ʻia ma lāʻau lapaʻau lapaʻau maʻi ʻaʻai māmā e komo pū me cisplatin, carboplatin, paclitaxel, a me docetaxel. ʻO nā lāʻau lapaʻau kūikawā a me kā lākou hui pū ʻana e pili ana i ke kahua a me ke ʻano o ka maʻi kanesa maʻi. Hiki ke koʻikoʻi nā hopena ʻaoʻao, a he mea koʻikoʻi ka hoʻokele pono.

Immunotherapy

Hoʻohana ka Immunotherapy i ke kino ponoʻī o ke kino e hakakā i ka maʻi kanesa. Ke hana nei kēia mau lāʻau lapaʻau ma o ka hoʻonui ʻana i ka hiki o ka ʻōnaehana pale ke ʻike a luku i nā maʻi kanesa. ʻO nā mea hoʻopaʻapaʻa checkpoint, e like me pembrolizumab a me nivolumab, he mau laʻana o nā lāʻau immunotherapy i hoʻohana ʻia ma lāʻau lapaʻau lapaʻau maʻi ʻaʻai māmā. Kuhi ʻia kēia mau lāʻau i nā protein e pale ai i ka ʻōnaehana pale mai ka hoʻouka ʻana i nā maʻi maʻi maʻi. Hiki iā lākou ke hāʻawi i nā pōmaikaʻi nui akā hele pū me nā hopena ʻaoʻao.

Nā Hana ʻē aʻe

Ma waho aʻe o nā lāʻau lapaʻau, hoʻokomo pinepine ʻia nā lāʻau lapaʻau ʻē aʻe i kahi ākea lāʻau lapaʻau lapaʻau maʻi ʻaʻai māmā hoʻolālā. Hiki i kēia mau mea ke komo: Radiation therapy: Hoʻohana i ka pāhawewe ikehu kiʻekiʻe no ka pepehi ʻana i nā maʻi maʻi maʻi. ʻO ka ʻoki ʻana: Wehe ʻia ka maʻi maʻi ʻaʻai. Ka mālama kākoʻo: Ke nānā aku nei i ka mālama ʻana i nā hopena ʻaoʻao a me ka hoʻomaikaʻi ʻana i ka maikaʻi o ke ola o ka mea maʻi.

Ke koho ʻana i ka Lapaʻau Pono

ʻO ke koho o lāʻau lapaʻau lapaʻau maʻi ʻaʻai māmā ʻano pilikino a hilinaʻi ʻia i kekahi mau kumu, e like me: ʻAno a me ka pae o ka maʻi maʻi ʻāʻī: pane ʻokoʻa nā ʻano like ʻole o ka maʻi kanesa i nā ʻano lapaʻau like ʻole. Hoʻopili ka pae o ka maʻi kanesa i nā hoʻoholo lapaʻau. ʻO ke olakino holoʻokoʻa o ka mea maʻi: Hiki i ke olakino maʻamau o ka mea maʻi a me nā kūlana mua ke hoʻopilikia i ko lākou ʻae ʻana i kekahi mau lāʻau lapaʻau. Hoʻāʻo Genetic: ʻO ka hoʻāʻo ʻana no nā hoʻololi kikoʻī i loko o nā keʻena maʻi maʻi hiki ke kōkua i ke alakaʻi ʻana i nā koho lapaʻau.

Nā hopena ʻaoʻao a me ka hoʻokele

Nui lāʻau lapaʻau lapaʻau maʻi ʻaʻai māmā hiki ke hana i nā hopena ʻaoʻao. Hiki i kēia mau mea mai ka maʻalahi a hiki i ke koʻikoʻi a ʻokoʻa ma muli o ka lāʻau lapaʻau kūikawā a me ka mea maʻi hoʻokahi. He mea nui e kūkākūkā i nā hopena ʻaoʻao me kāu mea mālama ola a hoʻomohala i nā hoʻolālā no kā lākou hoʻokele. He mea koʻikoʻi ke kamaʻilio wehe ʻana me kāu hui lapaʻau i ke kaʻina hana lapaʻau.

Kahi e loaʻa ai ka ʻike hou aku

No ka ʻike kikoʻī e pili ana i ka maʻi maʻi ʻaʻai a me kāna mālama ʻana, hiki iā ʻoe ke nīnau i nā kumu kaulana e like me ka National Cancer Institute (NCI) https://www.cancer.gov/ a me ka American Lung Association (ALA) https://www.lung.org/. E hoʻomanaʻo, ʻo ka ʻimi ʻana i nā ʻōlelo aʻo lapaʻau ʻoihana ka mea nui i ka hoʻokele ʻana i nā paʻakikī o ka mālama ʻana i ka maʻi kanesa. No ka mālama holomua a pilikino, e noʻonoʻo e nīnau i nā loea ma nā ʻoihana kaulana e like me ka Shandong Baofa Cancer Research Institute https://www.baofahospital.com/.

ʻAno Laʻau	Nā laʻana	Mechanism of Action	Hiki i nā hopena ʻaoʻao
ʻO nā mea pale EGFR	ʻO Gefitinib, Erlotinib	Hoʻopaʻa i ka hōʻailona EGFR	Rash, diarrhea, luhi
ʻO nā mea pale ALK	Crizotinib, Alectinib	Hoʻopaʻa i ka hōʻailona ALK	Nausea, luaʻi, constipation
Kemoterapi	Cisplatin, Carboplatin	Poino i ka DNA	Nausea, luaʻi, lauoho lauoho
Immunotherapy	Pembrolizumab, Nivolumab	Hoʻonui i ka pane immune	ʻO ka luhi, ka ʻūhū, ka ʻōpū

Kuhi ʻia kēia ʻike no nā kumu hoʻonaʻauao wale nō a ʻaʻole pono e manaʻo ʻia he ʻōlelo aʻoaʻo olakino. E kamaʻilio mau me kahi ʻoihana mālama ola kūpono no ka hōʻoia ʻana a me ka hoʻolālā lāʻau.