ka mālama ʻana i ka maʻi ʻaʻai pancreatic ke kumu o nā Halemai

ʻO ka mālama ʻana i ka maʻi maʻi pancreatic e pili ana i nā mea e like me ke kahua, kahi, a me ke olakino holoʻokoʻa. ʻO nā ala maʻamau e pili ana i ka hōʻoki ʻana, radiation, chemotherapy, a me ka lāʻau lapaʻau. ʻO ka hoʻomaopopo ʻana i nā kumu, mai nā genetic predispositions i nā kumu ola, kōkua i ka pale ʻana a me ka ʻike mua ʻana. ʻImi kēia alakaʻi i kēia mau ʻano a hōʻike i nā halemai kaulana i ʻike ʻia ka mālama ʻana i ka maʻi ʻaʻai pancreatic ke kumu o nā Halemai. Aia ʻo Shandong Baofa Cancer Research Institute ma ke alo o ka noiʻi ʻana i ka maʻi maʻi a me nā koho lapaʻau. He paʻakikī ka ʻike mua ʻana ma muli o kāna mau hōʻailona maʻalahi, no laila he mea koʻikoʻi ia e hoʻomaopopo i nā kumu pilikia a me nā hōʻailona hōʻailona. He kuleana koʻikoʻi ko ka pancreas i ka hana ʻana i nā enzymes e kōkua i ka hoʻoemi ʻana a me nā hormones e like me ka insulin e hoʻoponopono ai i ke kō koko. ʻO nā ʻano liʻiliʻi maʻamau ʻo ia ka neuroendocrine tumors (PNETs), e kū mai ana mai nā pūnaewele endocrine e hoʻohua ai i nā hormones.He aha ke kumu o ka maʻi maʻi pancreatic? ka mālama ʻana i ka maʻi ʻaʻai pancreatic ke kumu o nā Halemai. Aia kēia mau mea: Puhi: He mea koʻikoʻi koʻikoʻi, e hoʻonui ana i ka maʻi maʻi pancreatic. ʻObesity: ʻO ka nui o ke kaumaha a i ʻole ka momona e hoʻonui i ka pilikia. Diabetes: Hiki i ka maʻi diabetes ke hoʻonui i ka pilikia. ʻO ka maʻi pancreatitis mau loa: ʻO ka mumū o ka pancreas i ka manawa. Moʻolelo ʻohana: He moʻolelo ʻohana o ka maʻi ʻaʻai pancreatic a i ʻole kekahi mau genetic syndromes e like me BRCA1/2 mutations, Lynch syndrome, a me Peutz-Jeghers syndrome. makahiki: Piʻi ka pilikia me ka makahiki, ʻike pinepine ʻia i ka poʻe ʻelemakule. ʻAi: ʻO ka ʻai nui i ka ʻiʻo i hana ʻia a me ka ʻiʻo ʻulaʻula hiki ke hoʻonui i ka pilikia. ka mālama ʻana i ka maʻi ʻaʻai pancreatic ke kumu o nā Halemai pili i kekahi mau kumu, e like me ka pae o ka maʻi kanesa, kona wahi, a me ke olakino holoʻokoʻa o ka mea maʻi. Loaʻa nā ala maʻamau: ʻO ka ʻoki ʻana ʻo ia ka koho lapaʻau mua no ka maʻi maʻi pancreatic hiki ke hoʻihoʻi ʻia, ʻo ia hoʻi, hiki ke wehe loa ʻia ke koko. ʻO ke ʻano kikoʻī o ka ʻoki ʻana e pili ana i kahi o ka ʻōpū. Aia nā kaʻina hana maʻamau: ʻO ke kaʻina hana Whipple (Pancreaticoduodenectomy): ʻO ka wehe ʻana i ke poʻo o ka pancreas, kahi ʻāpana o ka ʻōpū liʻiliʻi, gallbladder, a me ka bile duct. ʻO ka maʻi pancreatectomy: ʻO ka wehe ʻana i ka huelo a me ke kino o ka pancreas, pinepine pū me ka spleen. Huina Pancreatectomy: Wehe ʻia ka pancreas holoʻokoʻa, e koi ana i ke ola holoʻokoʻa o ka enzyme a me ka insulin replacement.Radiation TherapyRadiation therapy hoʻohana i nā kukuna ikehu kiʻekiʻe e hoʻopaʻa a luku i nā pūnaʻi maʻi kanesa. Hiki ke ho'ohana 'ia ma mua o ke ka'a 'ana no ka emi 'ana o ke koko (neoadjuvant therapy), ma hope o ke ka'i 'ana no ka ho'opau 'ana i ke koena o ka ma'i 'a'ai (adjuvant therapy), a i 'ole ma ke 'ano he lapa'au mua ke hiki 'ole ke oki. Hiki ke hoʻohana wale ʻia a i hui pū ʻia me nā lāʻau lapaʻau ʻē aʻe e like me ke ʻoki a me ka radiation therapy. ʻO nā lāʻau lapaʻau lapaʻau maʻamau no ka maʻi ʻaʻai pancreatic ʻo ia ka gemcitabine, paclitaxel, a me fluorouracil (5-FU). Hoʻohana pinepine ʻia kēia mau lāʻau no nā poʻe maʻi me ka maʻi maʻi pancreatic kiʻekiʻe a me nā hoʻololi genetic kikoʻī. ʻO kahi laʻana nā lāʻau lapaʻau e huli ana i ke ala EGFR.ImmunotherapyImmunotherapy hoʻonui i ke kino o ke kino e hakakā i ka maʻi kanesa. ʻOiai ʻaʻole i hoʻohana nui ʻia no ka maʻi maʻi pancreatic, ke ʻimi nei nā hoʻokolohua lapaʻau e hoʻomau nei i kona hiki, ʻoi aku hoʻi no nā ʻōpū me nā biomarkers kikoʻī. Shandong Baofa Cancer Research Institute, Hoʻolaʻa mākou i ka paionia i nā koho lapaʻau hou no ka mālama ʻana i ka maʻi ʻaʻai pancreatic ke kumu o nā Halemai. Hāʻawi mākou i nā ʻano lapaʻau holomua, me: ʻO ka ʻoki kino liʻiliʻi: Ke hoʻohana nei i nā ʻenehana laparoscopic a me robotic e hōʻemi i ka manawa hoʻōla a hoʻomaikaʻi i nā hopena maʻi. ʻO ka lāʻau lapaʻau pololei: Ke hoʻohana nei i nā ʻenehana holomua e like me IMRT a me SBRT no ka hoʻopuka ʻana i nā koina radiation i manaʻo nui ʻia ʻoiai e mālama ana i ka ʻiʻo olakino. Nā Papahana Chemotherapy pilikino: Hoʻoponopono i nā regimen chemotherapy e pili ana i nā ʻano maʻi pilikino a me ka biology tumor. Nā hoʻokolohua lapaʻau: Ke komo nei i nā hoʻokolohua lapaʻau ʻokiʻoki e ʻimi i nā lāʻau lapaʻau hou a hoʻohiki no ka maʻi maʻi pancreatic. ka mālama ʻana i ka maʻi ʻaʻai pancreatic ke kumu o nā Halemai koʻikoʻi. E noʻonoʻo i kēia mau kumu: ʻike: E ʻimi i nā halemai me ka nui o nā mea maʻi maʻi maʻi pancreatic a me nā kauka lapaʻau ʻike, oncologists, a me nā lāʻau lapaʻau radiation. Hui Multidisciplinary: E hōʻoia i ka haukapila he pūʻulu multidisciplinary o nā loea e hui pū ana e hoʻomohala i nā hoʻolālā lapaʻau pilikino. ʻenehana kiʻekiʻe: E koho i kahi haukapila me nā ʻenehana diagnostic a me nā ʻenehana lapaʻau hou. Nā hoʻokolohua lapaʻau: E noʻonoʻo i nā halemai e hāʻawi ana i ke komo ʻana i nā hoʻokolohua lapaʻau no nā lāʻau lapaʻau hou. Nā lawelawe kākoʻo: E ʻimi i nā halemai e hāʻawi ana i nā lawelawe kākoʻo piha, me ka ʻōlelo aʻo meaʻai, ka mālama ʻana i ka ʻeha, a me ke kākoʻo naʻau. ka mālama ʻana i ka maʻi ʻaʻai pancreatic ke kumu o nā Halemai: Shandong Baofa Cancer Research Institute: ʻIke ʻia no kāna noiʻi holomua a me ka mālama maʻi. MD Anderson Cancer Center (USA): He kikowaena maʻi maʻi alakaʻi me ka manaʻo nui i ka noiʻi a me ka mālama ʻana i ka maʻi maʻi pancreatic. Mayo Clinic (USA): Hāʻawi i ka mālama piha a me kahi ala multidisciplinary i ka maʻi maʻi pancreatic. Halemai Johns Hopkins (USA): Kaulana no kona akamai i ke oki pancreatic. Noho me ka ma'i ma'i pancreatic hiki ke pa'akikī ka noho 'ana me ka ma'i 'a'ai pancreatic, akā loa'a ke kāko'o. He mea nui ka nānā 'ana i ka mālama 'ana i ke ola olakino, ka mālama 'ana i nā hō'ailona, a me ka 'imi 'ana i ke kāko'o no'ono'o mai ka 'ohana, nā hoaaloha, a i 'ole nā hui kāko'o. Nā Kūlana Kāko'o 'Oiai 'a'ohe ala pa'a e pale ai i ka ma'i 'a'ai pancreatic, hiki iā 'oe ke ho'emi i kou pilikia ma: Ha'alele i ka puhi paka: ʻO ka puhi paka kekahi kumu pilikia nui. Ka mālama ʻana i ke kaumaha olakino: Hoʻonui ka momona i ka pilikia. Ka mālama ʻana i ka maʻi diabetes: E hoʻopaʻa i kou pae kōpaʻa koko inā loaʻa iā ʻoe ka maʻi diabetes. ʻAi ʻana i kahi meaʻai olakino: E noʻonoʻo i nā huaʻai, nā mea kanu, a me nā kīʻaha piha. Ke kaupalena ʻana i ka ʻai ʻana i ka waiʻona: Hiki ke hoʻonui i ka nui o ka inu ʻana i ka waiʻona. ʻO ka ʻike mua ʻana a me ka hoʻomaʻamaʻa koʻikoʻi he mea nui ia no ka hoʻomaikaʻi ʻana i nā hopena ola. ʻO ka helu ola 5-makahiki e pili ana i ka pākēneka o nā maʻi e noho ana ma kahi o 5 mau makahiki ma hope o ka ʻike ʻia ʻana o ko lākou kanesa. Eia nō naʻe, he mea nui e hoʻomanaʻo i ka helu ʻana o ke ola ola a hiki ke hoʻololi ʻia ma muli o ke kūlana o kēlā me kēia. Ka Papa 5-Makahiki Ke Ola Ola (Akokoke) Wehewehe Ka Papa 0 ~ 20% Loaʻa nā maʻi maʻi maʻi ma ka lining o nā aʻa pancreatic wale nō. Ua kapa ʻia ʻo ia he carcinoma in situ. Ka Papa IA ~18% He 2 kenimika (cm) a emi mai paha ke koko a aia wale no ma ka pancreas. ʻO ka pae IB ~16% ʻOi aku ka nui ma mua o 2 knm ākea a aia wale nō ma ka pancreas. Ka Papa IIA ~9% Ua laha ka ma'i 'a'ai ma o aku o ka pancreatic i na kino a me na okana kokoke mai, aole nae i na puna lymph kokoke. Pae IIB ~7% Ua laha ka ma'i 'a'ai i nā pūnana lymph kokoke a ua laha paha ma waho o ka pancreas a hiki i nā ʻiʻo a me nā ʻōpū kokoke. Māhele III ~5% Ua laha ka maʻi kanesa i nā kīʻaha koko nui kokoke i ka pancreatic a ua laha paha i nā ʻōpū lymph kokoke. Ka Papa IV ~3% Ua laha ka ma'i 'a'ai ma na wahi mamao, e like me ke ake, akemāmā, a me ka peritoneum. Puna: ʻAmelika Hui Pū ʻIaManaʻo Hoʻomaopopo i nā kumu, ka mālama ʻana i ka maʻi ʻaʻai pancreatic ke kumu o nā Halemai, a he mea koʻikoʻi nā hoʻolālā pale no ka maʻi maʻi pancreatic. ʻO ka ʻike mua, ke komo ʻana i nā koho lapaʻau kiʻekiʻe, a me kahi hui mālama ola kākoʻo hiki ke hoʻopilikia nui i nā hopena. E kūkākūkā me kāu kauka e kūkākūkā i kāu mau pilikia pilikino a hoʻomohala i kahi hoʻolālā pilikino no ka pale ʻana a me ka ʻike mua ʻana.