Mwepụta ọgwụ na-achịkwa: Ntuziaka zuru oke 

nnyefe ọgwụ achịkwara achịkwa Emebere usoro iji wepụta ọgwụ ruo ogologo oge, na-enye ọtụtụ uru karịa ụzọ mbufe ọgwụ. Usoro ndị a na-edobe mkpokọta ọgwụ n'ime usoro ọgwụgwọ, na-ebelata mmetụta ndị na-adịghị mma ma na-emeziwanye nnabata onye ọrịa. Edemede a na-enyocha ụkpụrụ, ụdị, uru na ngwa nke nnyefe ọgwụ na-achịkwa achịkwa, na-enye nghọta zuru ezu nke ubi ọhụrụ a.

Ịghọta ntọhapụ a na-achịkwa

Kedu ihe bụ ntọhapụ a na-achịkwa?

Ntọhapụ a na-achịkwa na-ezo aka na usoro inyefe ọgwụ n'ogo a kara aka na ọnọdụ n'ime ahụ. N'adịghị ka usoro mwepụta ozugbo, nke na-ahapụ ọgwụ niile ngwa ngwa, nnyefe ọgwụ na-achịkwa achịkwa Usoro na-agbatị ntọhapụ nke ọgwụ ahụ n'ime awa, ụbọchị, ma ọ bụ ọbụna ọnwa. Usoro a na-enye mmetụta ọgwụgwọ na-agbanwe agbanwe ma na-ebelata ugboro ugboro nke doses.

Ụkpụrụ nke mwepụta a na-achịkwa

Ọtụtụ ụkpụrụ na-achịkwa nhazi na ọrụ nke ntọhapụ a na-achịkwa Sistemu:

• Mgbasa: Ntọhapụ ọgwụ na-achịkwa site na ọnụego nke ọgwụ na-agbasa site na matriks polymer.
• Mgbasa: Ntọhapụ ọgwụ na-achịkwa ọnụego nke matriks polymer na-agbaze ma ọ bụ mebie.
• Osmosis: Mwepụ ọgwụ ọjọọ na-akpata site na esemokwu nrụgide osmotic gafere n'otu akụkụ ahụ nke nwere ike ime ka ọ dị obere.
• Mgbaze: Ntọhapụ ọgwụ na-akpata site na mbelata nke nta nke nta nke matriks polymer.

Ụdị Sistemụ Mwepụta Achịkwaara

Sistemụ Matrix

Sistemu matrix gụnyere itinye ọgwụ n'ime matriks polymer. A na-ewepụta ọgwụ ahụ site na mgbasa site na matriks ma ọ bụ site na mmebi nke matriks n'onwe ya. Sistemu ndị a dị mfe imepụta yana enwere ike ịhazi ya iji nye profaịlụ ntọhapụ dị iche iche.

Sistemụ nchekwa nchekwa

Sistemụ nchekwa nchekwa nwere isi nwere ọgwụ ahụ nke akpụkpọ anụ polymer gbara ya gburugburu. A na-ahapụ ọgwụ ahụ site na akpụkpọ ahụ na ọnụ ọgụgụ a na-achịkwa. Sistemu ndị a na-enye njikwa zuru oke maka ntọhapụ ọgwụ mana ọ nwere ike ịdị mgbagwoju anya imepụta ya.

Sistemụ Osmotic

Sistemụ Osmotic na-eji nrụgide osmotic iji chịkwaa ntọhapụ ọgwụ. A na-etinye ọgwụ ahụ n'ime akpụkpọ anụ nke nwere ọkara, na mmiri na-adọta n'ime usoro site na osmosis. Nke a na-emepụta nrụgide nke na-ebupụ ọgwụ ahụ site na obere oghere. Sistemụ Osmotic na-enye ntọhapụ ọgwụ na-agbanwe agbanwe nke ukwuu.

Sistemụ na-emebi emebi

Usoro na-emebi emebi na-eji polymers na-emebi ma ọ bụ na-emebi ka oge na-aga, na-ahapụ ọgwụ ahụ ka polymer na-akụda. A na-ejikarị usoro ndị a eme ihe maka nnyefe ọgwụ ogologo oge.

Uru nke Mwepụta a na-achịkwa

Emelitere nnabata ndị ọrịa

Mbelata doses ugboro na-eme ka onye ọrịa na-agbaso usoro ọgwụ, karịsịa maka ọnọdụ adịghị ala ala.

Mmetụta Mbelata

Idobe mkpokọta ọgwụ n'ime windo ọgwụgwọ na-ebelata mgbanwe nke nwere ike ibute nsonaazụ ọjọọ.

Ịrụ Ọrụ Ọgwụgwọ emelitere

Ọkwa ọgwụ na-agbanwe agbanwe na-ebuli nsonaazụ ọgwụgwọ yana gbochie oge nke obere ọgwụgwọ ma ọ bụ mkpokọta ọgwụ na-egbu egbu.

Nnyefe ọgwụ ezubere iche

Ụfọdụ ntọhapụ a na-achịkwa Enwere ike ịhazi usoro iji nyefee ọgwụ ozugbo na anụ ahụ ma ọ bụ akụkụ ahụ akọwapụtara, na-abawanye arụmọrụ yana ibelata mkpughe usoro. Tụlee nyocha na-aga n'ihu na ụlọ ọrụ dịka Shandong Baofa Cancer Research Institute, nke na-elekwasị anya na ọgwụgwọ ezubere iche maka ọrịa dị iche iche.

Ngwa nke mwepụta a na-achịkwa

Ọrịa obi

Ntọhapụ a na-achịkwa A na-eji usoro ọgwụgwọ na-ebuga ọgwụ maka ọbara mgbali elu, angina, na ọnọdụ obi ndị ọzọ, na-eme ka njikwa ọbara mgbali elu na-agbanwe agbanwe na ibelata ihe ize ndụ nke nkụchi obi na ọrịa strok.

Ọrịa shuga mellitus

A na-ejikarị insulin na ọgwụ ndị ọzọ na-arịa ọrịa shuga ntọhapụ a na-achịkwa Sistemu na-eme ka ọkwa glucose dị n'ọbara guzosie ike ma melite njikwa glycemic.

Nlekọta mgbu

Ntọhapụ a na-achịkwa opioids na analgesics ndị ọzọ na-enye ihe mgbu na-adịgide adịgide, na-ebelata mkpa ọ dị maka ịṅụ ọgwụ ugboro ugboro na ibelata ihe ize ndụ nke ịṅụ ọgwụ ọjọọ.

Ọgwụgwọ ọrịa kansa

Ntọhapụ a na-achịkwa ọgwụ chemotherapy nwere ike ilekwasị anya na mkpụrụ ndụ kansa n'ụzọ dị irè karị, na-ebelata mmebi nke anụ ahụ dị mma yana ibelata mmetụta. Shandong Baofa Cancer Research Institute na-etinye aka na nyocha nke metụtara ngwa ntọhapụ a na-achịkwa na ọgwụgwọ ọrịa cancer.

Ngwa ndị ọzọ

Ntọhapụ a na-achịkwa a na-ejikwa ya n'ọtụtụ ngwa ndị ọzọ, gụnyere:

• Usoro ọgwụgwọ nnọchi homonụ
• Ọgwụgwọ nke nsogbu akwara ozi
• Ịgba ọgwụ mgbochi ọrịa
• Ọgwụ ọgwụgwọ ọrịa anụmanụ

Ọmụmaatụ nke ngwaahịa mwepụta a na-achịkwa

Ọgwụ ọnụ

Ọtụtụ ọgwụ ọnụ dị na ntọhapụ a na-achịkwa usoro, gụnyere:

• Metformin agbatịpụrụ maka ọrịa shuga
• Nifedipine gbatịpụrụ-ntọhapụ maka ọbara mgbali elu
• Oxycodone gbatịpụrụ-nhapụ maka njikwa mgbu

Transdermal patches

Ihe mgbochi transdermal na-ebuga ọgwụ site na akpụkpọ ahụ na ọnụ ọgụgụ a na-achịkwa. Ọmụmaatụ gụnyere:

• Ngwunye Nicotine maka ịkwụsị ise siga
• Fentanyl patches maka njikwa mgbu
• Hormone nnọchi patches

Ịkụnye

A na-etinye ihe nkedo n'ịwa ahụ nke na-ahapụ ọgwụ ruo ogologo oge. Ọmụmaatụ gụnyere:

• Mgbochi mgbochi afọ
• stent na-ekpochapụ ọgwụ

Ihe ịma aka na ntụzịaka ga-eme n'ọdịnihu

Ihe ịma aka

N'agbanyeghị ọtụtụ uru nke ntọhapụ a na-achịkwa, ọtụtụ ihe ịma aka ka dị:

• Ịmepụta mgbagwoju anya
• Ọnụ
• Mgbanwe na mwepụta ọgwụ
• Ihe gbasara onye ọrịa

Ntuziaka n'ọdịnihu

Nnyocha n'ọdịnihu na nnyefe ọgwụ na-achịkwa achịkwa lekwasịrị anya na:

• Na-emepe usoro nnyefe ọgwụ ọkaibe na nke ezubere iche
• Iji biodegradable na ihe ndị nwere ike imekọrịta ihe
• Ịhazi nnyefe ọgwụ na-adabere na mkpa onye ọrịa n'otu n'otu
• Na-ejikọta nanotechnology na microfluidics

Mmechi

nnyefe ọgwụ achịkwara achịkwa na-anọchi anya ọganihu dị ịrịba ama na nkà na ụzụ ọgwụ, na-enye ọtụtụ uru karịa usoro nnyefe ọgwụ. Ka nyocha na-aga n'ihu na teknụzụ ọhụrụ na-apụta. ntọhapụ a na-achịkwa Sistemu dị njikere ịrụ ọrụ dị mkpa na-abawanye ụba n'ịkwalite nsonaazụ ndị ọrịa yana ịkwalite ahụike ahụike.

Data na akụrụngwa

Nke a bụ ọmụmaatụ otu ụzọ nnyefe ọgwụ dị iche iche nwere ike isi tụnye n'ihe gbasara profaịlụ ntọhapụ ha. Biko mara na nke a bụ nnochite anya dị mfe maka naanị ihe atụ, na profaịlụ ntọhapụ n'ezie ga-adịgasị iche dabere n'ụdị ọgwụ a kapịrị ọnụ, nhazi na ihe ndị ọrịa.

* Mara: Data bụ ihe atụ na ụkpụrụ ga-adịgasị iche.

Nkwuputa: Edemede a bụ maka ebumnuche ozi na ọ bụghị naanị ndụmọdụ ahụike. Kpọtụrụ onye ọkachamara ahụike maka nsogbu ahụike ọ bụla ma ọ bụ tupu ịme mkpebi ọ bụla metụtara ọgwụgwọ gị.