China renal cell carcinoma pathology

China Renal Cell Carcinoma Pathology Outlines Ho Utloisisa Pathology of Renal Cell Carcinoma in ChinaSengoliloeng sena se fana ka kakaretso e akaretsang ea likarolo tsa pathological tsa renal cell carcinoma (RCC) naheng ea China, se shebane le mefuta e meng e tloaelehileng, mekhoa ea ho hlahloba, le litlamorao tsa tsoelo-pele. Re tla hlahloba lipatlisiso tsa morao-rao le litataiso tsa bongaka ho fana ka kutloisiso e hlakileng ea mofetše ona o atileng. Sesebelisoa sena se etselitsoe litsebi tsa tlhokomelo ea bophelo bo botle le bafuputsi ba nang le thahasello ho RCC pathology.

Epidemiology le Risk Factors ea RCC naheng ea China

Renal cell carcinoma ke phephetso e kholo ea bophelo bo botle ba sechaba Chaena. Le hoja litekanyetso tse nepahetseng tsa liketsahalo li fapana ho ea ka libaka, liphuputso li fana ka maikutlo a mokhoa o ntseng o phahama, o bonahatsang mekhoa ea lefats'e. Mabaka a 'maloa a kotsi a kenya letsoho ntlafatsong ea RCC, ho kenyelletsa ho tsuba, botenya, khatello ea mali le histori ea lelapa. Ho feta moo, ho pepesehela chefo e itseng tikolohong ho ka phetha karolo. Ho utloisisa mabaka ana a kotsi ke habohlokoa bakeng sa ho kenya ts'ebetsong mekhoa e sebetsang ea thibelo.

Pathological Classification ea RCC

Mofuta o ka sehloohong oa histological oa China renal cell carcinoma ke lisele tse hlakileng tsa RCC (ccRCC), tse ikarabellang bakeng sa linyeoe tse ngata. Leha ho le joalo, li-subtypes tse ling, tse kang papillary RCC, chromophobe RCC, le ho bokella duct RCC, le tsona lia etsahala. Phapang e nepahetseng ea pathological ke ea bohlokoa bakeng sa ho tataisa liqeto tsa kalafo le ho bolela esale pele hore na ho tla etsahala eng. Mekhoa ea sejoale-joale ea pathological, ho kenyeletsoa immunohistochemistry le profiling ea limolek'hule, e ntse e sebelisoa ka ho eketsehileng ho ntlafatsa ho nepahala ha tlhahlobo.

Hlakola Cell Renal Cell Carcinoma (ccRCC)

ccRCC e tšoauoa ka cytoplasm e hlakileng liseleng tsa hlahala ka lebaka la bongata ba glycogen le lipid content. Hangata e bontša mohlala oa lihlaha tse tiileng le li-tubules. Liphetoho tse khethehileng tsa limolek'hule, tse kang liphetoho tsa liphatsa tsa lefutso tsa VHL, hangata li amahanngoa le ccRCC. Ho utloisisa litšobotsi tsena tsa limolek'hule ke habohlokoa bakeng sa nts'etsopele ea phekolo e lebisitsoeng.

Mefuta e meng ea RCC

Papillary RCC e tšoauoa ka meaho e kang ea papillae, hangata e bonts'a prognosis e ntle ho feta ccRCC. Chromophobe RCC ha e tloaelehe 'me e bontša sebopeho sa eosinophilic cytoplasm. Ho bokella duct RCC ke mofuta o sa tloaelehang le o mabifi. Phapang e nepahetseng har'a li-subtypes tsena ke ea bohlokoa bakeng sa mekhoa e hlophisitsoeng ea phekolo.

Mekhoa ea Tlhahlobo ea RCC Chaena

Tlhahlobo ea China renal cell carcinoma hangata e kenyelletsa ho kopanya lithuto tsa litšoantšo (CT, MRI) le tlhahlobo ea histopathological ea biopsy kapa mehlala ea ho buoa. Tsoelo-pele ea mekhoa ea ho etsa litšoantšo, ho kenyelletsa le multiphasic CT, e ntlafatsa ho lemoha le ho khetholla bongata ba renal. Fine-needle aspiration biopsy e ka fana ka tlhaiso-leseling ea pele ea cytological, athe ho buuoa ka ho buuoa ho lumella tlhahlobo e hlakileng ea mafu.

Lintlha tsa Prognostic le Liphello tsa Phekolo

Lintlha tse 'maloa li susumetsa tsoelo-pele ea RCC, ho kenyelletsa le tumor stage (TNM staging), histological grade, le boteng ba metastasis. Sistimi ea sethala ea TNM e fana ka mokhoa o tloaelehileng oa ho arola likotsi. Ho feta moo, Sisteme ea maemo ea Fuhrman e lekola likarolo tsa nyutlelie tsa lisele tsa RCC ho bolela esale pele boitšoaro bo mabifi. Lintlha tsena li tataisa liqeto tsa phekolo, ho tloha ho ts'ebetso ea ho buoa ho ea ho liphekolo tse lebisitsoeng le immunotherapy.

Lipatlisiso le Litaelo tsa Kamoso

Patlisiso e ntseng e tsoela pele Chaena e tsepamisitse maikutlo ho ntlafatseng ho lemoha kapele, ho nchafatsa mekhoa ea tlhahlobo, le ho nts'etsapele liphekolo tse ncha tsa kalafo. China renal cell carcinoma. Sena se kenyelletsa liphuputso ho li-biomarker bakeng sa ho fumanoa kapele, ho lekola sepheo se secha sa kalafo, le liteko tsa bongaka tse hlahlobang mekhoa e mecha ea kalafo. Tšebelisano har'a bafuputsi, lingaka le baetsi ba melaoana ke ea bohlokoa ho ntšetsa pele kutloisiso le tsamaiso ea RCC Chaena.

Lethathamo: Papiso ea RCC Subtypes

Boitlhotlhollo: Litaba tsena ke tsa sepheo sa thuto feela 'me ha lia lokela ho nkoa e le keletso ea bongaka. Kamehla buisana le setsebi sa tlhokomelo ea bophelo bakeng sa mathata leha e le afe a bophelo bo botle kapa pele u etsa liqeto tse amanang le bophelo bo botle kapa phekolo ea hau.

Ho fumana lintlha tse ling mabapi le lipatlisiso tsa mofetše le mekhoa ea kalafo, ka kopo etela Setsi sa Lipatlisiso sa Kankere sa Shandong Baofa.