kalafo renal cell carcinoma pathology Lipetlele

Ho utloisisa Renal Cell Carcinoma Pathology le Khetho ea Kalafo Lipetleleng tse ka Sehloohong

Tataiso ena e pharaletseng e hlahloba pathology of renal cell carcinoma (RCC) le ho hlalosa mekhoa ea phekolo e fumanehang lipetleleng tse ka sehloohong tse sebetsanang le kankere ea urological. Re tla shebisisa mefuta e fapaneng ea RCC, mekhoa ea tlhahlobo, lits'ebetso tsa sethala, le mekhoa e fapaneng ea kalafo e kenyelletsang opereishene, kalafo e lebisitsoeng, immunotherapy, le kalafo ea radiation. Lintlha tse fanoeng li ikemiselitse ho matlafatsa batho ba batlang tlhahisoleseling mabapi le kalafo renal cell carcinoma pathology Lipetlele le dikgetho tsa bona.

Renal Cell Carcinoma (RCC) ke Eng?

Renal cell carcinoma (RCC) ke mofuta oa mofetše oa liphio o hlahang lera la li-tubules tse ka har'a liphio. E ikarabella bakeng sa boholo ba kankere ea liphio. Ho utloisisa pathology e khethehileng ea RCC ke habohlokoa bakeng sa ho tseba hore na ke efe e sebetsang ka ho fetisisa kalafo renal cell carcinoma pathology Lipetlele e ka fana. Tlaleho ea pathology e fana ka lintlha tse qaqileng mabapi le litšobotsi tsa hlahala, ho kenyelletsa le boemo ba eona le sethala, tse susumetsang haholo liqeto tsa kalafo.

Mefuta le Pathology ea Renal Cell Carcinoma

Ho na le li-subtypes tse 'maloa tsa RCC, e' ngoe le e 'ngoe e na le likarolo tse ikhethang tsa pathological le likarabo tse ka bang teng tsa kalafo. Li-subtypes tse tsebahalang haholo li kenyelletsa:

Hlakola Cell Renal Cell Carcinoma

Ena ke mofuta o tloaelehileng ka ho fetisisa oa RCC, o khetholloang ke cytoplasm e hlakileng liseleng tsa mofetše tlas'a microscope. Hangata lefu la eona le ama khetho ea phekolo, 'me mekhoa ea phekolo e lebisitsoeng hangata e sebetsa.

Papillary Renal Cell Carcinoma

Papillary RCC e na le likhakanyo tsa papillary (joaloka menoana). Hangata pathology ea eona e hloka mokhoa o fapaneng ha o bapisoa le lisele tse hlakileng tsa RCC.

Chromophobe Renal Cell Carcinoma

Subtype ena e khetholloa ke lisele tse silafatsang ka lidae tse tloaelehileng. Pathologies ea eona e ikhethang hangata e laela mekhoa e fapaneng ea kalafo.

Li-subtypes tse ling

Mefuta e sa tloaelehang ea RCC e teng, ho kenyelletsa ho bokella duct carcinoma le RCC e sa tsejoeng, e 'ngoe le e' ngoe e na le likarolo tse itseng tsa pathological tse hlokang tlhokomelo e khethehileng ho kalafo renal cell carcinoma pathology Lipetlele.

Tlhahlobo le Staging ea Renal Cell Carcinoma

Tlhahlobo e nepahetseng le maemo a bohlokoa bakeng sa moralo o sebetsang oa phekolo. Mekhoa ea ho hlahloba hangata e kenyelletsa:

Lithuto tsa ho Etsa Litšoantšo

CT scans, MRI scans, le ultrasound li sebelisoa ho bona liphio le ho lemoha hlahala. Mekhoa ena ea litšoantšo e thusa ho fumana boholo le sebaka sa hlahala, hammoho le boteng ba metastase leha e le efe (e hasane likarolong tse ling tsa 'mele).

Biopsy

Tlhahlobo ea biopsy e kenyelletsa ho ntša sampole ea linama tse nyane ka har'a hlahala bakeng sa tlhahlobo ea microscopic. Tlhahlobo ea pathological ea biopsy e bohlokoa bakeng sa ho netefatsa tlhahlobo, ho khetholla mofuta o itseng oa RCC, le ho lekola boemo ba hlahala (bohale).

Ho etsa sethala

Sistimi ea sethala, joalo ka sistimi ea TNM, e arola RCC ho latela boholo ba hlahala, sebaka, ho hasana ho li-lymph nodes tse haufi, le metastase e hole. Sethala se susumetsa haholo likhothaletso tsa kalafo.

Khetho ea Kalafo bakeng sa Renal Cell Carcinoma

Khetho ea kalafo bakeng sa RCC e ipapisitse le lintlha tse 'maloa, ho kenyeletsoa boemo ba mofetše, bophelo bo botle ba mokuli, le mofuta o ikhethileng oa RCC. Ea etellang pele kalafo renal cell carcinoma pathology Lipetlele fana ka mefuta e mengata ea phekolo, e ka kenyelletsang:

Ho buoa

Ho buuoa, joalo ka karolo ea nephrectomy (ho tlosoa ha hlahala feela) kapa nephrectomy e feteletseng (ho tlosoa ha liphio kaofela), ke khetho e tloaelehileng ea phekolo bakeng sa RCC ea sebakeng seo. Mofuta oa ho buuoa o itšetlehile ka lintlha tse 'maloa tse kenyeletsang boholo ba hlahala le sebaka.

Targeted Therapy

Litlhare tse reriloeng li sebelisa lithethefatsi tse lebisang liseleng tsa mofetše ka ho khetheha, ho fokotsa tšenyo ea lisele tse phetseng hantle. Hangata meriana ena e thibela liprotheine tse itseng tse amehang khōlong ea mofetše le ho phela.

Immunotherapy

Immunotherapy e sebelisa sesole sa 'mele ho loantša lisele tsa mofetše. E akarelletsa ho sebelisa meriana kapa liphekolo tse thusang sesole sa 'mele ho lemoha le ho senya lisele tsa mofetše.

Phekolo ea Mahlaseli

Kalafo ea radiation e sebelisa mahlaseli a matla ho bolaea lisele tsa mofetše. Leha e sa sebelisoe hangata joalo ka kalafo ea mantlha bakeng sa RCC, e ka bapala karolo ea tlhokomelo ea pholiso kapa ho alafa phetetso ea lehae.

Ho Khetha Sepetlele se Nepahetseng Bakeng sa Litlhoko tsa Hao

Ho bohlokoa ho khetha sepetlele se nang le tsebo ea oncology ea urological le rekoto e matla ea ho phekola RCC. Lintlha tse lokelang ho nahanoa li kenyelletsa boiphihlelo ba sepetlele ka mofuta o ikhethileng oa RCC, phihlello ea mahlale a tsoetseng pele a tlhahlobo le kalafo, le mokhoa oa sehlopha sa li-multidisciplinary mabapi le tlhokomelo ea mofets'e. Setsi sa Lipatlisiso sa Kankere sa Shandong Baofa ke setsi se tsebahalang se fanang ka tlhokomelo e felletseng bakeng sa bakuli ba renal cell carcinoma.

Boithorollo

Boitsebiso bo fanoeng sehloohong sena bo reretsoe merero ea thuto feela 'me ha boa lokela ho nkoa e le keletso ea bongaka. Kamehla buisana le setsebi se tšoanelehang sa tlhokomelo ea bophelo bakeng sa mathata leha e le afe a bophelo bo botle kapa pele u etsa liqeto tse amanang le bophelo bo botle kapa phekolo ea hau.