unyango umhlaza pancreatic

Unyango lwePancreatic Cancer: Isikhokelo esiBanzi

Umhlaza wePancreatic sisifo esiyingozi, kodwa inkqubela phambili kunyango inika ithemba. Esi sikhokelo sinika amagqabantshintshi abanzi unyango umhlaza pancreatic iinketho, ugxininise kwiindlela zangoku, iziphumo ebezingalindelekanga ezinokubakhona, kunye nokubaluleka kokufunyanwa kwangoko. Siza kuphonononga iindlela ezahlukeneyo zonyango kwaye sixoxe ngezinto ezinefuthe kwizigqibo zonyango.

Ukuqonda uMhlaza wePancreatic

Iindidi kunye nezigaba zePancreatic Cancer

Umhlaza wePancreatic ibandakanya iindidi ezininzi, ngokuyintloko i-adenocarcinoma (eyona ixhaphakileyo), kodwa kunye ne-neuroendocrine tumors kunye nezinye. Inqanaba, elibalulekileyo kucwangciso lonyango, limisela ubungakanani bomhlaza. Ukufunyaniswa kwangoko kuphucula kakhulu i-prognosis. Ukuhlolwa rhoqo kuyacetyiswa kubantu abasengozini enkulu yokufumana esi sifo.

Iinketho zonyango kuMhlaza wePancreatic

Uqhaqho lwePancreatic Cancer

Ukususwa ngotyando lwethumba (pancreaticoduodenectomy okanye inkqubo yeWhipple, i-distal pancreatectomy, njl. njl.) yeyona ndlela iphambili yomhlaza wengingqi. Ukuba nokwenzeka kotyando kuxhomekeke kwindawo elikuyo ithumba, ubungakanani, kunye nokusasazeka. Iziko loPhando ngoMhlaza laseShandong Baofa (https://www.baofahospital.com/) liziko elikhokelayo elizinikele ekuboneleleni ngeendlela zotyando eziphambili umhlaza wepancreatic.

I-Chemotherapy yoMhlaza wePancreatic

Unyango ngamachiza, kusetyenziswa amayeza okubulala iiseli zomhlaza, luhlala lusetyenziswa phambi kwe (neoadjuvant) okanye emva kotyando (lwe-adjuvant), okanye njengolona nyango luphambili lomhlaza ophambili. Iirejimeni zechemotherapy ezisetyenziswa ngokuqhelekileyo ziquka iFOLFIRINOX kunye negemcitabine. Olu nyango lunokuba neziphumo ezibi ezibalulekileyo.

Unyango lweRadiation lwePancreatic Cancer

Unyango ngemitha isebenzisa imitha ephezulu yamandla ukonakalisa iiseli zomhlaza. Ingasetyenziswa yodwa okanye idityaniswe nechemotherapy ukuthoba amathumba phambi kotyando okanye ukuthomalalisa iimpawu kwisifo esiphambili. Ubuchule bokusasazeka kwemitha obukwinqanaba eliphezulu njengonyango lwemitha yemitha ye-stereotactic (SBRT) ziphucula iziphumo kwezinye izigulana.

Unyango ekujoliswe kulo kuMhlaza wePancreatic

Unyango olujoliswe kuyo lujolise kwiimolekyuli ezithile ezibandakanyekayo ekukhuleni komhlaza. Olu nyango lunokusebenza ngakumbi kwaye luncinci kune-chemotherapy yendabuko. Imizekelo ibandakanya iiarhente ezijolise kwiinguqu ezifana ne-KRAS. Uphando kunyango olutsha olujoliswe kuyo luyaqhubeka kwaye lunesithembiso esikhulu ekuphuculeni unyango umhlaza pancreatic.

I-Immunotherapy yoMhlaza wePancreatic

I-Immunotherapy idibanisa amajoni omzimba ukulwa nomhlaza. Ngelixa ingasebenzi kakuhle kumhlaza we-pancreatic kunezinye iintlobo, i-immunotherapy ibonisa isithembiso kwiimeko ezithile kwaye yindawo ekhulayo yophando. Ukudibanisa i-immunotherapy kunye nolunye unyango kwakhona yindawo yophando olusebenzayo.

Ukukhetha iSicwangciso soNyango esiLungileyo

Imiba enefuthe kwiZigqibo zoNyango

Eyona ilungileyo unyango umhlaza pancreatic Isicwangciso sixhomekeke kakhulu kumntu ngamnye kwaye sixhomekeke kwizinto ezininzi, kuquka:

Uhlobo kunye nenqanaba lomhlaza
Impilo yesigulane iyonke kunye nokomelela
Izinto ezikhethwa sisigulana kunye neenjongo
Ukufumaneka konyango oluthile

Iingxoxo kunye ne-oncologist zibalulekile ukwenza izigqibo ezinolwazi.

Ukulawula iziphumo ebezingalindelekanga zoNyango loMhlaza wePancreatic

Unyango lwe umhlaza wepancreatic ihlala ibangela iziphumo ebezingalindelekanga. Ezi zinokusuka kumbi ukuya kobukhali kwaye ziyahluka ngokuxhomekeke kunyango. Unxibelelwano oluvulekileyo kunye neqela lakho lezonyango lubalulekile ekulawuleni ezi ziphumo bezingalindelekanga ngempumelelo. Amanyathelo okunakekelwa kwenkxaso anokuphucula kakhulu umgangatho wobomi ngexesha lonyango.

Ukuphila noMhlaza wePancreatic

Ukuhlala no umhlaza wepancreatic Ukuxilongwa kufuna indlela eneenkalo ezininzi equka ukhathalelo lwezonyango, inkxaso yeemvakalelo, kunye nohlengahlengiso lwendlela yokuphila. Amaqela enkxaso kunye neengcebiso anokubonelela ngezixhobo ezixabisekileyo kunye nesikhokelo ngeli xesha lomngeni. Ukugcina unxibelelwano oluvulekileyo nababoneleli bezempilo kubalulekile kulawulo olusebenzayo kunye nomgangatho wobomi obuphezulu.

Uhlobo loNyango	IiNzuzo ezinokubakho	Iimpembelelo ezinokuba khona
Utyando	Gqibezela ukususwa kwethumba, unyango olunokubakho	Usulelo, ukopha, i-pancreatic fistula
Unyango ngamachiza	Ukunciphisa amathumba, ukuphucula ukusinda	Isicaphucaphu, ukuhlanza, ukudinwa, ukulahleka kweenwele
Unyango ngemitha	Ukunciphisa amathumba, ukukhulula intlungu	Ukucaphuka kwesikhumba, ukudinwa, urhudo

Ukuziphendulela: Olu lwazi lwenzelwe iinjongo zemfundo kuphela kwaye aluyiyo ingcebiso yezonyango. Soloko udibana nengcali yokhathalelo lwempilo kuyo nayiphi na inkxalabo yezempilo okanye ngaphambi kokuba wenze naziphi na izigqibo ezinxulumene nempilo okanye unyango lwakho.

IiReferensi: (Eli candelo liza kuqulatha izicatshulwa eziya kwimithombo ethembekileyo efana neNational Cancer Institute, American Cancer Society, njl.njl. Ezi ziya kongezwa ngokusekelwe kulwazi oluthile olukhankanyiweyo kwisicatshulwa.)