i-papillary renal cell carcinoma

I-Papillary Renal Cell Carcinoma: Isikhokelo esiBanzi

I-Papillary renal cell carcinoma (i-papillary renal cell carcinoma) luhlobo lomhlaza wezintso oluqala kunwebu lwemibhobho yezintso. Esi sikhokelo sibonelela ngolwazi olunzulu kwiintlobo zalo, ukuxilongwa, unyango, kunye nokuxilongwa. Ukuqonda le meko kubalulekile ekubhaqweni kwangaphambili kunye nolawulo olusebenzayo.

Ukuqonda iPapillary Renal Cell Carcinoma

Iintlobo zePapillary Renal Cell Carcinoma

I-Papillary renal cell carcinoma ihlelwa kwiindidi ezimbini eziphambili ngokusekelwe kwiimpawu zeseli: uhlobo lwe-1 kunye nohlobo lwe-2. Uhlobo lwe-1 luxhaphake kakhulu kwaye ngokuqhelekileyo lune-prognosis engcono kune-2, ehlala ihambelana nokukhula okunamandla kunye nomngcipheko ophezulu wokuphindaphinda. Ulwahlulo olongezelelekileyo lunokwenziwa ngokusekwe kwiimpawu ezongezelelweyo ze-histological. Ukuhlelwa okuchanekileyo kubalulekile kwizigqibo zonyango ezikhokelayo.

Iimpawu zePapillary Renal Cell Carcinoma

Abantu abaninzi abakwinqanaba lokuqala i-papillary renal cell carcinoma amava akukho zimpawu zibonakalayo. Njengoko i-tumor ikhula, nangona kunjalo, iimpawu zinokuvela. Oku kunokubandakanya i-hematuria (igazi kumchamo), intlungu yecala, ubunzima besisu obucacileyo, okanye ukunciphisa umzimba. Kubalulekile ukuba udibane nogqirha ukuba ufumana nayiphi na kwezi mpawu. Ukufunyanwa kwangoko kuphucula kakhulu iziphumo zonyango.

Ukuxilongwa kwePapillary Renal Cell Carcinoma

Ukuxilongwa ngokuqhelekileyo kuqala ngezifundo zokucinga ezifana ne-ultrasound, i-CT scan, okanye i-MRI. I-biopsy isoloko iyimfuneko ukuqinisekisa ukuxilongwa kunye nokumisela uhlobo oluthile lwe i-papillary renal cell carcinoma. Iimvavanyo ezingaphaya zinokuqhutywa ukujonga ubungakanani bokusasazeka komhlaza (inqanaba).

Iinketho zonyango lwePapillary Renal Cell Carcinoma

Ukususwa ngotyando

Ukususwa ngotyando lwezintso ezichaphazelekayo (i-nephrectomy engaphelelanga okanye epheleleyo) idla ngokuba lolona nyango luphambili i-papillary renal cell carcinoma. Ubungakanani botyando buxhomekeke kubungakanani, indawo, kunye nenqanaba lomhlaza. Ubuchwephesha botyando obungenelelayo busetyenziswa rhoqo ukunciphisa iingxaki zasemva kotyando.

Unyango ekujoliswe kulo

Iindlela zonyango ezijoliswe kuzo, ezifana ne-tyrosine kinase inhibitors (TKIs), zijolise ekuthinteleni iiprotheni ezithile ezikhuthaza ukukhula kweeseli zomhlaza. La mayeza anokusetyenziswa yedwa okanye adityaniswe nolunye unyango, ngakumbi kwiimeko eziphambili okanye zemetastatic. Ukukhethwa kwonyango olujoliswe kuyo kuxhomekeke kwiimpawu ezithile zofuzo ze-tumor.

Immunotherapy

I-Immunotherapy idibanisa amajoni omzimba ukulwa neeseli zomhlaza. I-Checkpoint inhibitors luhlobo lwe-immunotherapy olunokuthi lusebenze ekunyangeni i-papillary renal cell carcinoma, ngakumbi kwizigulane ezinezifo eziphambili. Olu nyango lusoloko lusetyenziswa xa ludibene nolunye unyango.

Unyango ngemitha

Unyango ngemitha lusebenzisa imitha yamandla aphezulu ukubulala iiseli zomhlaza. Ngelixa ingelonyango lokuqala lwe i-papillary renal cell carcinoma, ingasetyenziselwa ukulawula intlungu okanye ukulawula ukukhula kwe-tumor kwizigaba eziphambili okanye kwiimeko apho utyando alukho ukhetho.

I-Prognosis kunye noNonophelo lokulandela

Iprognosis ye i-papillary renal cell carcinoma iyahluka kakhulu ngokuxhomekeke kwizinto ezininzi, kubandakanywa uhlobo, inqanaba, kunye nebakala lomhlaza, kunye nempilo yomguli ngokubanzi. Ukunyamekela okulandelwa rhoqo, kubandakanywa nezifundo ze-imaging kunye neemvavanyo zegazi, kubalulekile ukubeka iliso ukuphindaphinda kunye nokufumanisa nayiphi na imiba emitsha ngokukhawuleza. Intsebenziswano esondeleyo kunye ne-oncologist yakho ibalulekile kulawulo lwexesha elide.

Izibonelelo kunye neNkxaso

Ngolwazi oluthe vetshe kunye nenkxaso, cinga ngokuqhagamshelana ne Umbutho womhlaza waseMelika okanye i Iziko leSizwe leSifo seswekile kunye neDigestive and Kidney Diseases. Kuba izigulane kwiphondo Shandong, i IZiko loPhando ngoMhlaza laseShandong Baofa inikeza ukhathalelo olubanzi lomhlaza kunye nenkxaso.

Uphando olongezelelweyo kunye novavanyo lwezonyango

Uphando oluqhubayo luhlala luphucula ukuqonda kwethu i-papillary renal cell carcinoma kunye nokuphuhlisa unyango olutsha nolusebenzayo ngakumbi. Izigulana zinokunqwenela ukuphonononga ulingo lweklinikhi njengendlela enokwenzeka yokufikelela kunyango oluqalayo. I-oncologist yakho inokunika isikhokelo ekufumaneni izilingo ezifanelekileyo.

I-Disclaimer: Olu lwazi lujoliswe kwiinjongo zemfundo kuphela kwaye aluyiyo ingcebiso yezonyango. Soloko udibana nengcali yokhathalelo lwempilo kuyo nayiphi na inkxalabo yezempilo okanye ngaphambi kokuba wenze naziphi na izigqibo ezinxulumene nempilo okanye unyango lwakho.