unyango lomhlaza wemiphunga oluphindaphindiweyo

Umhlaza wemiphunga oqhelekileyo ubhekisa ekubuyeni kweeseli zomhlaza emva konyango lokuqala. Indlela yonyango ye unyango lomhlaza wemiphunga oluphindaphindiweyo kuxhomekeke kwizinto ezifana nohlobo lomhlaza wemiphunga, unyango lokuqala olufunyenweyo, ixesha ukususela kunyango lokuqala, kunye nempilo yonke yomguli. Iinketho zonyango eziqhelekileyo ziquka ichemotherapy, unyango lweradiation, unyango olujoliswe kuyo, unyango lwe-immunotherapy, kunye nokuhlinzwa. umhlaza wemiphunga ophindaphindiweyo. Oku kuphinda kwenzeke kwindawo efanayo nomhlaza wokuqala (ukuphindaphinda kwendawo), kwii-lymph nodes ezikufutshane (ukuphindaphinda kwengingqi), okanye kwizitho ezikude (ukuphindaphinda okude). Ukuqonda ipateni yokuphindaphinda kubalulekile ekunqumeni isicwangciso sonyango esisebenzayo.Iintlobo zokuphindaphinda Ukuphindaphinda kwendawo: Umhlaza ubuyela kwakuloo miphunga okanye kwindawo apho wawuqale khona. Ukuphindaphinda kweNgingqi: Umhlaza ubuyela kwii-lymph nodes kufutshane nesiza somhlaza sokuqala. Ukuphindaphinda okukude: Umhlaza unwenwela kwamanye amalungu omzimba, njengengqondo, amathambo, isibindi, okanye eminye imiphunga.Iizinto ezinefuthe kwizigqibo ngoNyangoIzinto ezininzi ziyaqwalaselwa xa kusenziwa isigqibo ngesicwangciso sonyango. unyango lomhlaza wemiphunga oluphindaphindiweyo: Uhlobo lomhlaza wemiphunga: Umhlaza wemiphunga yeseli encinci (SCLC) kunye nomhlaza wemiphunga weseli ongeyincinci (NSCLC) uneendlela ezahlukeneyo zonyango. Unyango lokuqala: Unyango olufunyenwe ekuqaleni luya kuba nefuthe kwiinketho ezilandelayo. Ixesha ukusukela kuNyango lokuqala: Ithuba elide phakathi konyango lokuqala kunye nokuphindaphinda kunokubonisa imeko enyangekayo ngakumbi. Impilo iyonke: Impilo yesigulana jikelele kunye nesimo sokusebenza zizinto ezibalulekileyo ekufuneka ziqwalaselwe. Ubungakanani bokuPhinda: Nokuba ukuvela kwakhona kukwasekhaya, kwingingqi, okanye kude kuchaphazela ukhetho lonyango. Utshintsho lwemfuza: Uvavanyo lotshintsho lwemfuza oluthile lunokunceda ekuqinisekiseni ukufaneleka kunyango olujoliswe kuyo.Iinketho zoNyango oluQhelekileyo loMhlaza oQondayo wemiphungaUnyango olwahlukeneyo luyafumaneka umhlaza wemiphunga ophindaphindiweyo. Indlela ethile iya kuxhomekeka kwizinto ezikhankanywe ngasentla.I-ChemotherapyI-Chemotherapy isebenzisa amayeza ukubulala iiseli zomhlaza. Ihlala isetyenziselwa zombini i-SCLC kunye ne-NSCLC, ngakumbi xa umhlaza usasazekile. Irejimeni ethile yechemotherapy iya kuxhomekeka kuhlobo lomhlaza wemiphunga kunye nonyango lwangaphambili. IZiko loPhando ngoMhlaza laseShandong Baofa lizinikele kwiingcali zeoncologists ezineminyaka yamava ekusebenziseni iChemotherapy ukunyanga umhlaza wemiphunga.Unyango lweRadiation TherapyRadiation isebenzisa imitha yamandla aphezulu ukubulala iiseli zomhlaza. Ingasetyenziselwa ukunyanga ukuphindaphinda kwendawo okanye kwingingqi, okanye ukunciphisa iimpawu kwiimeko zokuphindaphinda okude. Inokuthi ihanjiswe ngaphandle okanye ngaphakathi (i-brachytherapy) .I-Targeted TherapyIzidakamizwa zonyango ezijoliswe kuzo zijolise kwiimolekyuli ezithile ezibandakanyekayo ekukhuleni kweeseli zomhlaza kunye nokuphila. Olu nyango lusebenza kakhulu xa iiseli zomhlaza zineenguqu ezithile zofuzo, ezifana ne-EGFR, ALK, okanye i-ROS1. Ukuvavanyelwa olu tshintsho lubalulekile. Imizekelo ibandakanya: I-EGFR inhibitors: I-Gefitinib, i-erlotinib, i-afatinib, i-osimertinib I-ALK inhibitors: Crizotinib, alectinib, ceritinib, brigatinib, lorlatinib I-ROS1 inhibitors: Crizotinib, entrectinibImmunotherapyImmunotherapy inceda amajoni omzimba ukulwa umhlaza. I-immune checkpoint inhibitors, njenge-pembrolizumab, i-nivolumab, kunye ne-atezolizumab, isetyenziswa ngokubanzi kwi unyango lomhlaza wemiphunga oluphindaphindiweyo, ngakumbi kwi-NSCLC. Basebenza ngokuthintela iiprotheyini ezithintela amajoni omzimba ekuhlaseleni iiseli zomhlaza.UtyandoUtyando lunokuba lukhetho lokuphindaphinda kwendawo, ngakumbi ukuba umhlaza uvalelwe kwindawo enye kwaye isigulane sisempilweni ngokwaneleyo ukuba senze utyando. I-Wedge resection, i-lobectomy, okanye i-pneumonectomy inokuqwalaselwa.Izilingo zeClinicalIzilingo zekliniki zibonelela ngokufikelela kunyango olutsha kunye novavanyo. Izigulane ezine umhlaza wemiphunga ophindaphindiweyo banokufuna ukucinga ngokuthatha inxaxheba kulingo lwezonyango lokuphonononga amayeza abukhali.Amaqhinga oNyango lweentlobo zoMhlaza weMiphuphu oPhindayo ongeyiyo uMncinci weSeli yemiphunga (NSCLC)Unyango lwe NSCLC yarhoqo kuxhomekeke ekubeni umhlaza unoguquko olujoliswe kuyo. Ukuba uguqulo lukhona, unyango olujoliswe kulo kaninzi lulo lonyango lodidi lokuqala. Ukuba akukho tshintsho lufunyenweyo, i-immunotherapy, ichemotherapy, okanye indibaniselwano yazo zombini inokusetyenziswa. Ukuphindaphinda kwendawo kunokunyangwa ngotyando okanye ngonyango lwemitha.Umhlaza weMiphunga yeSeli encinci eQwalasayo (SCLC)I-SCLC eqhubekayo idla ngokunyangwa ngechemotherapy, nokuba isigulana sifumene unyango lwechemotherapy ekuqaleni. I-Topotecan liyeza eliqhelekileyo le-chemotherapy. Ulingo lwezonyango lukwayingqwalasela ebalulekileyo kwizigulane ezine SCLC ephindaphindiweyo.Ukulawula iimpawu kunye neziphumo ebezingalindelekanga Ukulawula iimpawu kunye neziphumo ebezingalindelekanga yinxalenye ebalulekileyo unyango lomhlaza wemiphunga oluphindaphindiweyo. Oku kunokubandakanya ukulawulwa kweentlungu, ukuxhaswa kwesondlo, kunye nokunyamekelwa kwenkxaso ukujongana nemiphumo emibi evela kunyango, njengesicaphucaphu, ukukhathala, nokulahleka kweenwele. umhlaza wemiphunga ophindaphindiweyo kunokuba lucelomngeni. Izigulana zisenokuba neemvakalelo ezahlukahlukeneyo, kuquka uloyiko, ukuxhalaba nokudandatheka. Amaqela enkxaso, iingcebiso, kunye nokhathalelo lokuthomalalisa uncedo lunokunceda izigulane kunye neentsapho zazo ukuba zijamelane nemingeni engokweemvakalelo nesebenzayo yokuphila nayo. umhlaza wemiphunga ophindaphindiweyo.Inkqubela phambili yoNyango lweMiphuphu yeMiphuphu eQhubelayo Uphando luyaqhuba ukuphuhlisa unyango olutsha nolusebenzayo ngakumbi umhlaza wemiphunga ophindaphindiweyo. Ezi nkqubela zibandakanya: Inoveli yoNyango ekuJoliswe kulo: Amachiza amatsha ajolise kwiinguqulelo ezithile ayaphuhliswa. IiNdlela eziPhuculweyo ze-Immunotherapy: Abaphandi baphonononga iindlela ezintsha zokomeleza amajoni omzimba ukulwa nomhlaza, ezinje ngonyango oludityanisiweyo lwe-immunotherapy. Iyeza elenzelwe wena: Ukulungelelanisa unyango kwisigulana ngasinye ngokusekwe kwiprofayili yemfuza kunye nezinye izinto ziya zibaluleka ngakumbi.Iziko loPhando loMhlaza laseShandong Baofa: Ukuzibophelela kuCancer CareShandong Baofa Cancer Research Institute lizinikele ekuboneleleni ngokhathalelo oluphezulu lomhlaza, kubandakanywa iindlela zonyango olubanzi. unyango lomhlaza wemiphunga oluphindaphindiweyo. Iqela lethu leengcali ze-oncologists, oogqirha botyando, i-radiation oncologists, kunye neengcali ezixhasayo zisebenza kunye ukuphuhlisa izicwangciso zonyango lomntu ngamnye. Unokufunda ngakumbi malunga neziko lethu apha. Iziko lethu lijongene nokunyanga iintlobo zomhlaza eziquka umhlaza wemiphunga. UkuqukumbelaUnyango lomhlaza wemiphunga oluphindaphindiweyo ifuna indlela ebanzi nezimeleyo. Ukuqonda izinto ezichaphazela izigqibo zonyango, ukuhlola iindlela zonyango ezikhoyo, kunye nokulawula iimpawu zizinto zonke ezibalulekileyo zokunyamekela. Ngophando oluqhubekayo kunye nokuqhubela phambili kunyango, kukho ithemba leziphumo eziphuculweyo kwizigulane ezine umhlaza wemiphunga ophindaphindiweyo.