isigaba 3 non small cell lung cancer unyango

Inqanaba lesi-3 IiKhetho zoNyango lweMiphunga yeSeli engeNcinci Eli nqaku libonelela ngesishwankathelo esibanzi seenketho zonyango zenqanaba lesi-3 lomhlaza wemiphunga weseli engeyincinci (NSCLC), kubandakanywa utyando, ichemotherapy, unyango lweradiation, unyango olujoliswe kuyo, kunye nonyango lwamajoni omzimba. Iphonononga inkqubela phambili yamva nje kwaye inceda abaguli baqonde ukhetho lwabo ngokubonisana ne-oncologist yabo.

Inqanaba lesi-3 UKhetho loNyango oluNgelulo oluNcinane lweSeli yeMiphuphu

Inqanaba lesi-3 umhlaza wemiphunga weseli ongekho mncinci (NSCLC) luxilongo olunzima, kodwa ukuqhubela phambili kwi-oncology yezonyango kubonelela ngeendlela ezininzi zonyango. Eyona ndlela ilungileyo ixhomekeke kwizinto ezahlukeneyo, kubandakanya uhlobo oluthile kunye nenqanaba lomhlaza, impilo yakho iyonke, kunye nezinto ozikhethayo. Eli nqaku lijolise ekunikeni ukuqonda okucacileyo konyango olukhoyo, kodwa kubalulekile ukukhumbula ukuba olu lwazi akufanelekanga endaweni yokubonisana nogqirha wakho we-oncologist. Baya kwenza isicwangciso sonyango lomntu siqu ngokusekelwe kwiimeko zakho ezizodwa.

Ukuqonda iNqanaba lesi-3 le-NSCLC

Inqanaba lesi-3 le-NSCLC lihlelwe ngokwezigaba ze-IIA kunye ne-IIIB, ebonisa ubungakanani bokusasazeka komhlaza. Inqanaba IIIA libandakanya umhlaza oye wasasazeka kwii-lymph nodes ezikufutshane, ngelixa i-IIB ibandakanya ukubandakanyeka kwe-lymph node kunye nezitho ezikufutshane. Iqonga elichanekileyo liyimfuneko ekumiseleni esona sicwangciso sisebenzayo sonyango. Iimvavanyo zokucinga ezifana ne-CT scans kunye ne-PET scans zisetyenziselwa ukubeka inqanaba lomhlaza ngokuchanekileyo.

IiNdlela zoNyango lweNqanaba lesi-3 le-NSCLC

Utyando

Utyando lunokuba lukhetho kwezinye izigulana ezinenqanaba lesi-3 le-NSCLC, ngakumbi ezo zinesifo sendawo. Uhlobo lotyando olwenziweyo luxhomekeke kwindawo kunye nobukhulu bethumba. Oku kunokubandakanya ukususa ithumba kunye nenxalenye yemiphunga (lobectomy okanye pneumonectomy) kunye ne-lymph nodes ezinokuthi zichaphazeleke. Iinketho zotyando zivavanywa ngokuqhelekileyo ngokusekelwe kwizinto ezizimeleyo kumxholo weqela lezinto ezininzi. IZiko loPhando ngoMhlaza laseShandong Baofa ibonelela ngobuchule obubanzi botyando kwi-oncology.

Unyango ngamachiza

Unyango ngamachiza, kusetyenziswa amachiza okubulala iiseli zomhlaza, lunyango olusisiseko senqanaba lesi-3 umhlaza wemiphunga weseli ongekho mncinci. Ingasetyenziswa phambi kotyando (neoadjuvant chemotherapy) ukucutha ithumba, emva kotyando (i-adjuvant chemotherapy) ukunciphisa umngcipheko wokuphinda, okanye njengonyango lokuqala ukuba utyando alunakwenzeka. Iirejimeni ezahlukeneyo zechemotherapy zikhona, kwaye ukhetho luxhomekeke kwizinto ezibandakanya impilo yesigulana kunye neempawu ezithile zethumba.

Unyango ngemitha

Unyango ngemitha lusebenzisa imitha yemitha ephezulu ukutshabalalisa iiseli zomhlaza. Ihlala isetyenziswa ngokudibeneyo ne-chemotherapy kwinqanaba lesi-3 umhlaza wemiphunga weseli ongekho mncinci, mhlawumbi ngaxeshanye okanye ngokulandelelana. Unyango lweradiation lunokunceda ukunciphisa amathumba, ukuthomalalisa iimpawu, kunye nokuphucula amazinga okusinda. Unyango lwemitha ye-Stereotactic body radiation (SBRT) luhlobo oluchaneke kakhulu lonyango lwemitha olunikezela ngeedosi eziphezulu zemitha kwithumba ngelixa unciphisa umonakalo kwizihlunu ezisempilweni ezingqongileyo.

Unyango ekujoliswe kulo

Unyango ekujoliswe kulo ngamayeza ajolise ngokukodwa kwiiseli zomhlaza ngokusekelwe kwiinguqu zabo zemfuza. Ukuba eyakho umhlaza wemiphunga weseli ongekho mncinci ineenguqu ezithile zofuzo, ezifana nokuguqulwa kwe-EGFR okanye ukulungiswa kwakhona kwe-ALK, unyango olujoliswe kuyo lunokuba lukhetho olusebenzayo lonyango. Olu nyango lunikezela ngesenzo esijolise ngakumbi, esinokuba neziphumo ebezingalindelekanga ezimbalwa xa kuthelekiswa nechemotherapy yesintu. IZiko loPhando ngoMhlaza laseShandong Baofa isebenzisa ubuchule obuphambili kunye nobuchwepheshe ukuvavanya iiprofayili zemfuzo.

Immunotherapy

I-Immunotherapy idibanisa amajoni omzimba ukulwa nomhlaza. Iziyobisi ze-Immunotherapy, ezifana ne-checkpoint inhibitors, zinokunceda amajoni omzimba aqaphele kwaye ahlasele iiseli zomhlaza ngokufanelekileyo. I-Immunotherapy isetyenziswa ngakumbi kunyango lwe umhlaza wemiphunga weseli ongekho mncinci, ngokuphindaphindiweyo ngokudibanisa nezinye iindlela zonyango, kwaye ibonise isithembiso ekuphuculeni iziphumo kwezinye izigulane. Olu hlobo lonyango lube yinkqubela phambili ebalulekileyo kubantu abathile bezigulane.

Ukukhetha iSicwangciso soNyango esiLungileyo

Olona cwangciso lonyango lwenqanaba lesi-3 umhlaza wemiphunga weseli ongekho mncinci igqitywe liqela leengcali zezempilo, kubandakanywa i-oncologists, oogqirha botyando, i-radiation oncologists, kunye nezinye iingcali. Baza kuthathela ingqalelo ngononophelo iimeko zakho, ezinje ngempilo yakho iyonke, ubungakanani bokusasazeka komhlaza, kunye nezinto ozikhethayo, ukuphuhlisa isicwangciso sonyango somntu kunye nesibanzi. Unxibelelwano oluvulekileyo neqela lakho lokhathalelo lwempilo luyimfuneko kuyo yonke inkqubo yonyango.

Iimvavanyo zeklinikhi

Ukuthatha inxaxheba kulingo lwezonyango kunokubonelela ngokufikelela kunyango olukwinqanaba eliphezulu kwaye kube negalelo kwinkqubela phambili umhlaza wemiphunga weseli ongekho mncinci uphando. Ugqirha wakho we-oncologist unokuxoxa malunga nokuba ukuthatha inxaxheba kulingo lwezonyango kunokuba kufanelekile kuwe.

I-Disclaimer: Le ngcaciso yenzelwe iinjongo zemfundo kuphela kwaye akufanele ithathwe njengengcebiso yezonyango. Soloko udibana nomboneleli wakho wezempilo ngazo naziphi na iinkxalabo zempilo okanye ngaphambi kokuba wenze naziphi na izigqibo ezinxulumene nempilo okanye unyango lwakho.