isigaba 3a unyango lomhlaza wemiphunga

Inqanaba 3A UMhlaza Wemiphunga: IiKhetho Zonyango kunye neOngameleyo Eli nqaku libonelela ngamagqabantshintshi abanzi okhetho lonyango kunye noxilongo lwenqanaba 3A lomhlaza wemiphunga. Sigubungela iindlela ezahlukeneyo zonyango, kubandakanya utyando, ichemotherapy, unyango lweradiation, kunye nonyango ekujoliswe kulo, sixoxa ngokusebenza kwazo, iziphumo ebezingalindelekanga ezinokubakho, kunye nokufaneleka kweeprofayili zesigulana ezahlukeneyo. Ingcaciso enikelwe apha yenzelwe iinjongo zemfundo kwaye akufuneki ithathe indawo yengcebiso yezonyango. Soloko udibana ne-oncologist yakho ngesicwangciso sonyango lomntu.

Inqanaba 3A Umhlaza Wemiphunga: Iinketho zonyango kunye neNjongo

Inqanaba 3A umhlaza wemiphunga imele umngeni obalulekileyo kwi-oncology, ebonakala ngokusasazeka komhlaza kwiilymph nodes ezikufutshane. Ukuqonda iindlela zonyango ezikhoyo kunye neziphumo zazo ezinokubakho kubalulekile kwizigulane kunye neentsapho zazo. Esi sikhokelo sijonge ukubonelela ngolwazi olucacileyo, olufutshane malunga isigaba 3a unyango lomhlaza wemiphunga, igxininisa ukubaluleka kokhathalelo lomntu kunye nokwenza izigqibo ngokubambisana neqela lakho lezempilo. Khumbula, ulwazi olulapha lwenzelwe iinjongo zemfundo kwaye akufuneki luthathe indawo yokubonisana nabasebenzi bezonyango.

Ukuqonda iNqanaba 3A Umhlaza wemiphunga

Ngaphambi kokuba ujonge kunyango, kubalulekile ukuqonda izinto ezithile isigaba 3A umhlaza wemiphunga. Eli nqanaba libonisa ukuba umhlaza usasazeke kwii-lymph nodes kwicala elifanayo lesifuba njenge-tumor (N2), kodwa kungekhona kwii-lymph nodes kwelinye icala lesifuba okanye kwiindawo ezikude. I-subtype ethile yomhlaza wemiphunga (iseli encinci okanye iseli engeyincinci) ikwachaphazela kakhulu izicwangciso zonyango. Ukulinganisa okuchanekileyo kwenziwa ngeemvavanyo ze-imaging ezifana ne-CT scans, i-PET scans, kunye ne-bronchoscopy, kunye ne-biopsies.

IiNdlela zoNyango lweSigaba 3A soMhlaza weMiphunga

Unyango lwe isigaba 3A umhlaza wemiphunga Ibandakanya indibaniselwano yonyango, edla ngokubizwa ngokuba lunyango lwe-multimodal. Eyona ndlela ifanelekileyo ixhomekeke kwizinto ezininzi, kuquka impilo yesigulane ngokubanzi, uhlobo oluthile kunye nendawo yethumba, kunye nobungakanani bokubandakanyeka kwe-lymph node.

Utyando

Utyando lunokuba lukhetho kwezinye izigulane ezine isigaba 3A umhlaza wemiphunga, ngakumbi abo banokubandakanyeka okulinganiselweyo kunye nempilo enhle iyonke. Uhlobo lotyando lunokusuka kwi-lobectomy (ukususwa kwe-lung lobe) ukuya kwi-pneumonectomy (ukususwa komphunga uphela). Uqhaqho loqhaqho lujolise ekususeni zonke iiseli zomhlaza ezibonakalayo.

Unyango ngamachiza

I-Chemotherapy lunyango lwenkqubo olusebenzisa amayeza ukubulala iiseli zomhlaza kuwo wonke umzimba. Idla ngokusetyenziswa phambi kotyando (neoadjuvant chemotherapy) ukucutha ithumba okanye emva kotyando (i-adjuvant chemotherapy) ukunciphisa umngcipheko wokuphinda. Iirejimeni ezininzi zechemotherapy ziyafumaneka, kwaye ukhetho luxhomekeke kwizinto ezifana nohlobo lomhlaza kunye neempawu zesigulana. Iirejimeni eziqhelekileyo ziquka i-cisplatin kunye ne-etoposide, okanye i-carboplatin kunye ne-paclitaxel.

Unyango ngemitha

Unyango ngemitha lusebenzisa imitha yamandla aphezulu ukubulala iiseli zomhlaza. Ingasetyenziswa yodwa okanye idityaniswe nolunye unyango. Kwi isigaba 3A umhlaza wemiphunga, unyango ngeradiation lunokusetyenziswa ngaphambi kotyando (neoadjuvant radiotherapy) okanye emva kotyando (adjuvant radiotherapy), okanye njengenxalenye yonyango lwekhemoradiation ngaxeshanye. Unyango lwemitha yemitha ye-stereotactic (SBRT) luhlobo oluchane kakhulu lwemitha yemitha ehambisa iidosi eziphezulu zemitha yemitha kwithumba kwiiseshini ezimbalwa.

Unyango ekujoliswe kulo

Unyango ekujoliswe kulo ngamachiza ajolise ngokukodwa kwiiseli zomhlaza ngaphandle kokonakalisa iiseli eziqhelekileyo. Ukusetyenziswa kwonyango olujoliswe kuyo luchongwa yi-genetic makeup ye-tumor. Ngokomzekelo, ukuba ithumba ligcina utshintsho oluthile lwemfuza (njenge-EGFR, ALK, ROS1), unyango olujoliswe kuyo njenge-EGFR inhibitors okanye i-ALK inhibitors inokusebenza kakhulu.

UkuKhethwa koNyango kunye ne-Prognosis

Ukukhethwa kweyona ndlela yonyango yonyango isigaba 3A umhlaza wemiphunga yinkqubo yentsebenziswano phakathi kwesigulane kunye neqela labo le-oncology. Oku kubandakanya uphononongo ngononophelo lwempilo yesigulana iyonke, iimpawu zethumba, kunye neengenelo ezinokubakho kunye nobungozi bokhetho ngalunye lonyango. Uqikelelo lwe isigaba 3A umhlaza wemiphunga iyahluka kakhulu ngokuxhomekeke kwizinto ezifana histology ithumba, ubungakanani ukubandakanyeka lymph node, kunye nempendulo yesigulane kunyango. Ngelixa imbonakalo inokuba ngumceli mngeni, ukuqhubela phambili kunyango kuye kwawaphucula kakhulu amazinga okuphila kwiminyaka yakutshanje. Ukuxoxa ngoxilongo ngokuphandle nangokunyaniseka neqela lakho lezempilo kubalulekile ekwenzeni izigqibo ezizizo kunye nokucwangcisela ikamva.

Ukukhetha iZiko loNyango eliLungileyo

Ukukhetha iziko lomhlaza eliqeqeshiweyo kubaluleke kakhulu ekufumaneni olona khathalelo lunokwenzeka isigaba 3A umhlaza wemiphunga. Khangela amaziko aneengcali ze-oncologists, amaqela e-multidisciplinary, ukufikelela kubuchwephesha obuphezulu, kunye nokuzinikela kukhathalelo olujoliswe kwisigulane. Phanda kwaye uthelekise iinketho ezahlukeneyo, ugxile kubuchule babo kunyango lomhlaza wemiphunga, kwaye ungathandabuzi ukubuza imibuzo ukuqinisekisa ukuba uziva ukhululekile ngokhetho lwakho.

Ngolwazi oluthe kratya ngokhetho oluphambili lonyango lomhlaza, ungacinga ngokuqhagamshelana IZiko loPhando ngoMhlaza laseShandong Baofa ukudibana. Banikezela ngoluhlu olubanzi lweenkonzo kunye nobuchwephesha bokusika ukulawula esi sifo esinzima. Khumbula ukuxoxa ngayo yonke imiba yonyango lwakho kunye neqela lakho lokhathalelo lwempilo ukwenza ezona zigqibo zilungileyo kwimpilo yakho.

I-Disclaimer: Le ngcaciso yenzelwe iinjongo zemfundo kuphela kwaye akufanele ithathwe njengengcebiso yezonyango. Soloko udibana nomboneleli wakho wezempilo ukuze ufumane ukuxilongwa kunye nonyango lwazo naziphi na iimeko zonyango.