iimpawu umhlaza pancreatic

Iimpawu umhlaza pancreatic zihlala zifihlakeleyo kumanqanaba okuqala, nto leyo eyenza ukuba ukufunyanwa kwangoko kube lucelomngeni. Iimpawu eziqhelekileyo ziquka intlungu yesisu, ukulahleka kwesisindo esingenakuchazwa, i-jaundice (i-yellowing yesikhumba kunye namehlo), utshintsho kwimikhwa yamathumbu, kunye nesifo sikashukela esitsha. Uvavanyo lonyango olukhawulezileyo lubalulekile ukuba ufumana nayiphi na kwezi mpawu, njengoko ukuxilongwa kwangoko kuphucula kakhulu iziphumo zonyango. Eli nqaku liza kuphonononga iimpawu ezahlukahlukeneyo ezinxulumene nazo iimpawu umhlaza pancreatic, iindlela zokuxilonga, kunye nokhetho olukhoyo lonyango.Ukuqonda uMhlaza wePancreaticI-pancreas lilungu elibekwe emva kwesisu elidlala indima ebalulekileyo ekucoleni nasekulawuleni iswekile yegazi. Umhlaza wodaka lwenzeka xa iiseli ezingaqhelekanga zikhula ngokungalawulekiyo kudakada. Kukho iindidi ezimbini eziphambili: amathumba e-exocrine, axhaphake kakhulu, kunye namathumba e-endocrine. I-Adenocarcinoma lolona hlobo luxhaphakileyo lomhlaza wepancreatic. Nangona kunjalo, ezininzi zezi mpawu zinokubangelwa zezinye iimeko. Ngoko ke, kubalulekile ukubonisana nodokotela ukuze ufumane ukuxilongwa okufanelekileyo. Intlungu yesisu Intlungu yesisu yenye yezona zinto zixhaphakileyo iimpawu umhlaza pancreatic. Ngokuqhelekileyo iqala njengentlungu ebuhlungu kwisisu esingaphezulu esinokuthi siphume ngasemva. Intlungu inokuba mandundu emva kokutya okanye xa ulele.Ukuncipha kobunzima obungachazwangaOkubalulekileyo kunye nokungachazwanga ukwehla kobunzima bolunye malunga neempawu. Oku kunokuba ngenxa ye-malabsorption (i-pancreas engavelisi i-enzymes eyaneleyo yokugaya ukutya) okanye utshintsho kwi-metabolism ebangelwa ngumhlaza.I-JaundiceJaundice, ebonakaliswe ngokuphuzi kwesikhumba kunye nabamhlophe bamehlo, kwenzeka xa i-tumor ivimba i-bile duct. Olu thintelo luthintela i-bilirubin, into ephuzi eveliswa sisibindi, ukuba ikhutshwe, ibangele ukuba yakhiwe emzimbeni.Utshintsho kwimikhwa yamathumbu Utshintsho kwimikhwa yamathumbu, njengohudo, ukuqunjelwa, okanye i-fatty stools (i-steatorrhea), ingenzeka ngenxa yokukhubazeka kwe-pancreas ukuvelisa i-enzyme yokugaya. I-Steatorrhea iphumela kwizitulo eziphaphathekileyo, ezinobuninzi, kunye nevumba elibi.Isifo seswekile esitsha sokuQala umhlaza wePancreatic ngamanye amaxesha unokukhokelela ekukhuleni kwesifo seswekile esitsha okanye wenze ukuba isifo seswekile esikhoyo kube nzima ukusilawula. Oku kungenxa yokuba i-pancreas ivelisa i-insulin, kwaye umhlaza unokuphazamisa lo msebenzi.Ezinye Iimpawu ezinokuthi zinokwenzeka I-Nausea kunye nokuhlanza Ukulahlekelwa ngumdla wokutya Ukudinwa Amahlwili egazi Ukwandiswa kwe-gallbladder okanye isibindi Izinto ezinobungozi kwiPancreatic CancerIzinto ezininzi ezinokonyusa umngcipheko wokukhula. iimpawu umhlaza pancreatic. Ezi ziquka: Ukutshaya ukutyeba kakhulu Isifo seswekile Isifo sokudumba esingapheliyo Imbali yentsapho yomhlaza wepancreatic Ezinye ii-syndromes zofuzo, ezifana ne-BRCA2, i-Peutz-Jeghers syndrome, kunye ne-Lynch syndrome. Ubudala: Umngcipheko wonyuka ngokweminyaka, uqhele ukwenzeka emva kweminyaka engama-45. Ukuxilongwa kwePancreatic CancerUkuba iimpawu umhlaza pancreatic kurhanelwa, ugqirha uya kwenza uviwo olucokisekileyo lomzimba kwaye ayalele iimvavanyo ezahlukeneyo zokuxilonga. Olu vavanyo lunokunceda ukufumanisa ukuba umhlaza ukhona na, inqanaba lawo, kunye nokuba usanwenwe kusini na.I-Imaging Tests I-Computed Tomography (CT) Scan: I-CT scan isebenzisa ii-X-reyi ukwenza imifanekiso eneenkcukacha yodakada kunye namalungu ajikelezileyo. Umfanekiso weMagnetic Resonance (MRI): I-MRI isebenzisa imagnethi kunye namaza kanomathotholo ukuvelisa imifanekiso eneenkcukacha yodakada. I-Endoscopic Ultrasound (EUS): I-EUS ibandakanya ukufaka ityhubhu ebhityileyo, ebhetyebhetye eneprobe ye-ultrasound kummizo kunye nesisu ukufumana imifanekiso esondeleyo ye-pancreas. Le nkqubo inokusetyenziselwa ukufumana isampuli yethishu ye-biopsy. I-Positron Emission Tomography (PET) Skena: Ngokuqhelekileyo kudibaniswa ne-CT scan, i-PET scans inokunceda ukufumanisa iiseli zomhlaza ezinokuthi zingabonakali kwezinye iimvavanyo ze-imaging.I-BiopsyA biopsy ibandakanya ukuthatha isampuli yezicubu ezincinci kwi-pancreas ukuze zihlolwe phantsi kwe-microscope. Le kuphela kwendlela yokuxilonga ngokuqinisekileyo iimpawu umhlaza pancreatic. I-Biopsies inokufumaneka ngexesha le-EUS, utyando, okanye ngenaliti ye-biopsy ekhokelwa yi-imaging.Uvavanyo lwegazi, olufana ne-CA 19-9 yovavanyo lwe-tumor marker, lunokunceda ukufumanisa izinto ezikhutshwe ngamaseli omhlaza. Nangona kunjalo, ezi mvavanyo azisoloko zichanekile kwaye ziqhele ukusetyenziswa kunye nezinye iindlela zokuxilonga.Unyango loNyango lwePancreatic CancerTreatment for iimpawu umhlaza pancreatic kuxhomekeke kwinqanaba kunye nendawo yomhlaza, kunye nempilo yonke yesigulane. Iinketho zonyango eziqhelekileyo zibandakanya: UtyandoUtyando luhlala lunyango oluphambili lomhlaza we-pancreatic, ngakumbi ukuba umhlaza usendaweni kwaye awusasazekanga. Inkqubo ye-Whipple (pancreaticoduodenectomy) lutyando oluqhelekileyo lwamathumba abekwe kwintloko ye-pancreas. Olunye ukhetho lotyando lubandakanya i-distal pancreatectomy (ukususwa komsila we-pancreas) kunye ne-pancreatectomy iyonke (ukususwa kwe-pancreas yonke).I-ChemotherapyI-Chemotherapy isebenzisa iziyobisi ukubulala iiseli zomhlaza. Ingasetyenziswa phambi kotyando ukucutha ithumba, emva kotyando lokubulala naziphi na iiseli zomhlaza eziseleyo, okanye njengonyango lokuqala lomhlaza wepancreatic. Iziyobisi eziqhelekileyo ze-chemotherapy ezisetyenziselwa ukunyanga umhlaza we-pancreatic ziquka i-gemcitabine, i-paclitaxel, kunye ne-cisplatin.Unyango lwe-Radiation TherapyRadiation therapy isebenzisa imiqadi yamandla amakhulu ukubulala iiseli zomhlaza. Ingasetyenziswa yodwa okanye idityaniswe nechemotherapy, ngaphambi okanye emva kotyando. I-Stereotactic body radiation therapy (SBRT) luhlobo lonyango lokusasazeka ngemitha olunikezela ngeedosi eziphezulu zokusasazeka kwemitha kwindawo echanekileyo.Unyango oluJoliswe ekuJolisweni lusebenzisa amachiza ajolise kwiimolekyuli ezithile ezibandakanyekayo ekukhuleni kweeseli zomhlaza. Imizekelo ibandakanya iziyobisi ezijolise kwindlela ye-EGFR okanye i-PARP inhibitors kwizigulane ezine-BRCA mutations.ImmunotherapyImmunotherapy isebenzisa amajoni omzimba ukulwa nomhlaza. Nangona ingasetyenziswanga ngokuqhelekileyo kumhlaza we-pancreatic njengezinye iintlobo zomhlaza, i-immunotherapy inokuba yinto ekhethiweyo kwezinye izigulane ezineenguqu ezithile zofuzo. iimpawu umhlaza pancreatic. Oku kunokubandakanya ukulawulwa kweentlungu, inkxaso yesondlo, kunye nokucebisa ngokweemvakalelo. IZiko loPhando ngoMhlaza laseShandong Baofa inikezela ngeenkonzo ezibanzi zokhathalelo lonyango ukunceda izigulane zilawule iimpawu zazo kwaye ziphucule impilo yazo yonke. Indlela yeSibhedlele saseBaofa kukhathalelo lomhlaza idibanisa unyango olukumgangatho ophezulu kunye nonyango oluxhasayo ukuqinisekisa ukuba izigulane zifumana ukhathalelo olupheleleyo nolomntu ngamnye. iimpawu umhlaza pancreatic iyahluka ngokuxhomekeke kwinqanaba lokuxilonga, impilo yesigulana iyonke, kunye nonyango olufunyenweyo. Ukufunyaniswa kwangoko kunye nonyango kuphucula kakhulu amazinga okusinda. Izinga leminyaka emihlanu lokusinda kumhlaza wepancreatic uphezulu kakhulu kunenqanaba eliphambili. Ngokutsho kwe-American Cancer Society, izinga lokusinda leminyaka emi-5 kuzo zonke izigaba zomhlaza wepancreatic limalunga ne-11%. Nangona kunjalo, la manani ayi-avareji kwaye anokwahluka kakhulu kumntu nomntu. [1]Nantsi itheyibhile eshwankathela amazinga okusinda ngokwenqanaba, ngokutsho kweAmerican Cancer Society. Nceda uqaphele ukuba olu luqikelelo jikelele kwaye iziphumo zomntu ngamnye zinokwahluka. Inqanaba le-5-Year Survival Rate Localized (Evalelwe kwi-Pancreas) I-44% yeNgingqi (Ukusasaza kwiiTissues ezikufutshane okanye i-Lymph Nodes) I-16% Ekude (Ukusasaza kwii-Organs ezikude) 3% Zonke izigaba ezidibeneyo 11% ukuThintelwa kunye nokuFunyaniswa kwaPhakathiNangona kungekho ndlela eqinisekisiweyo yokuthintela umhlaza womhlaza, unokunciphisa umngcipheko wokuphila kwe-pancreatic. Oku kuquka: Ukuyeka ukutshaya Ukugcina ubunzima obunempilo Ukutya ukutya okunesondlo okuneziqhamo kunye nemifuno egcwele iziqhamo kunye nemifuno Ukulawula isifo seswekile Ukunciphisa ukuselwa kotywala Ukuhlolwa rhoqo nogqirha kubalulekile ukuze ubhaqwe kwangethuba, ingakumbi kubantu abanomngcipheko iimpawu umhlaza pancreatic. Ukuba ufumana naziphi na iimpawu, funa unyango ngokukhawuleza.I-Disclaimer: Eli nqaku libonelela ngolwazi ngokubanzi malunga neempawu zomhlaza we-pancreatic kunye nonyango kwaye akufanele kuthathwe njengengcebiso yezonyango. Soloko unxibelelana negcisa lezempilo eliqeqeshiweyo ukuze ufumane isikhokelo somntu zonyango.1 Umthombo: American Cancer Society. 'Amazinga okusinda kuMhlaza wePancreatic'. https://www.cancer.org/cancer/types/pancreatic-cancer/detection-diagnosis-staging/survival-rates.html (Ifikeleleke ngo-Oktobha 26, 2023).