unyango umhlaza esibindini

Iinketho zonyango kuMhlaza wesibindi

Umhlaza wesibindi, imeko enzima, ifuna ngokukhawuleza kwaye isebenze unyango. Esi sikhokelo sibanzi siphonononga ezahlukeneyo unyango iinketho zomhlaza wesibindi, ukubonelela ngengqiqo ekusebenzeni kwabo, ukufaneleka, kunye nemiphumo enokubakho. Siza kugocagoca kwiinkqubela-phambili zamva nje kunye neendlela ezisetyenziswayo ukulwa nesi sifo, sikuncede uqonde indlela eya ekusebenzeni unyango lomhlaza esibindini.

Ukuqonda uMhlaza Wesibindi

Iintlobo zomhlaza wesibindi

Iindidi ezininzi zomhlaza zinokuchaphazela isibindi, eyona ixhaphakileyo yi-hepatocellular carcinoma (HCC) kunye ne-cholangiocarcinoma. Ukuqonda uhlobo oluthile lomhlaza wesibindi kubalulekile ekumiseleni okona kulungileyo unyango iqhinga. Inkqubo yokuxilongwa ibandakanya iimvavanyo ze-imaging (ezifana ne-CT scans kunye ne-MRI), i-biopsies, kunye novavanyo lwegazi ukuvavanya ukusebenza kwesibindi kunye nokubona iimpawu ze-tumor.

Umhlaza Wesibindi

Iqonga lichaza ubungakanani bokunwenwa komhlaza. Oku kubalulekile ukumisela okufanelekileyo unyango isicwangciso. Ukwenziwa kweqonga kubandakanya indibaniselwano yezifundo zokucinga kunye ne-biopsy enokubakho. Inqanaba lomhlaza lichaphazela ngokuthe ngqo unyango iinketho ezikhoyo, ukusuka kwiinkqubo ezihlasela kancinci ukuya kunyango olubanzi.

Iinketho zonyango kuMhlaza wesibindi

Utyando

Ukususwa ngotyando kwenxalenye yomhlaza yesibindi, eyaziwa ngokuba yi-hepatic resection okanye ukutshintshwa kwesibindi, yeyona nto iphambili. unyango ukhetho lomhlaza wesibindi kwinqanaba lokuqala. I-Hepatic resection ijolise ekususeni i-tumor ngelixa igcina izicubu zesibindi ezinempilo kangangoko kunokwenzeka. Ukutshintshwa kwesibindi kuqwalaselwa xa izicubu zesibindi ezisele zingakwazi ukusebenza ngokufanelekileyo emva kokutshatyalaliswa, okanye ukuba umhlaza usasazeke ngaphaya kwesibindi.

Unyango ngamachiza

I-Chemotherapy isebenzisa amayeza ukubulala iiseli zomhlaza. Nangona ayisoloko iphambili unyango kumhlaza wesibindi, ingasetyenziswa kwiimeko ezahlukeneyo: njengonyango lwe-neoadjuvant ngaphambi kotyando ukucutha ithumba; njengonyango lwe-adjuvant emva kokuhlinzwa ukunciphisa umngcipheko wokuphindaphinda; okanye njengento yokuthomalalisa unyango ukunciphisa iimpawu kunye nokuphucula umgangatho wobomi kwizigaba eziphambili. Irejimeni ethile ye-chemotherapy ixhomekeke kuhlobo kunye nenqanaba lomhlaza.

Unyango ngeRadio

I-radiotherapy isebenzisa imitha ephezulu yamandla ukubulala iiseli zomhlaza. Unyango lwemitha yemitha yangaphandle luqhele ukusetyenziswa kumhlaza wesibindi, rhoqo ngokudityaniswa nolunye unyango. Ingasetyenziselwa ukunciphisa amathumba, ukulawula iintlungu, kunye nokuphucula umgangatho wobomi. Ukusetyenziswa kweendlela ekujoliswe kuzo ngeradiotherapy ezifana ne-stereotactic body radiation therapy (SBRT) ivumela ukuhanjiswa okuchanekileyo kwemitha kwithumba, kuncitshiswe umonakalo kwizihlunu ezisempilweni ezingqongileyo.

Unyango ekujoliswe kulo

Unyango ekujoliswe kulo ngamachiza ajolise ngokukodwa kwiiseli zomhlaza, ezishiya iiseli ezisempilweni zingonzakali. Ezi zihlala zisetyenziswa kwizigulane ezinomhlaza wesibindi ophezulu kwaye zinokulawulwa ngomlomo okanye nge-intravenously. Ukusebenza kwonyango olujoliswe kuyo kuxhomekeke kuhlobo oluthile kunye neempawu zeeseli zomhlaza.

Immunotherapy

I-Immunotherapy idibanisa amajoni omzimba ukulwa neeseli zomhlaza. Ii-Checkpoints inhibitors, uhlobo lwe-immunotherapy, zisetyenziselwa ukunceda amajoni omzimba abone ngcono kwaye ahlasele iiseli zomhlaza. Olu nyango lunokusebenza, ngakumbi kwiintlobo ezithile zomhlaza wesibindi kwaye xa zidityaniswe nolunye unyango. Iziphumo ebezingalindelekanga ziyahluka kakhulu phakathi kwabantu.

Embolization

I-Transarterial chemoembolization (TACE) yinkqubo ehlasela kancinci ehambisa amayeza echemotherapy ngokuthe ngqo kwithumba nge-hepatic artery, evalela ukuhamba kwegazi kwithumba. Oku kugxininisa i-chemotherapy kwaye kunciphisa impembelelo kuwo wonke umzimba.

Ukukhetha Unyango Olululo

Ukukhethwa kweyona nto ingcono unyango ngenxa umhlaza esibindini kuxhomekeke kwizinto eziliqela, kuquka uhlobo nenqanaba lomhlaza, impilo yomguli ngokubanzi, nezinto azikhethayo. Iqela leengcali ezininzi, kubandakanya i-oncologists, oogqirha botyando, ii-radiologists, kunye nabanye abaqeqeshi bezempilo, baya kusebenza kunye ukuphuhlisa umntu. unyango isicwangciso.

Le ngcaciso yenzelwe iinjongo zemfundo kuphela kwaye ayithathi indawo yeengcebiso zonyango zobungcali. Kubalulekile ukuba udibane nengcali yokhathalelo lwempilo ukuze ufumane uxilongo oluchanekileyo kwaye unyango iinketho. Ngolwazi oluthe vetshe okanye ukwenza ishedyuli yokubonisana, ndwendwela IZiko loPhando ngoMhlaza laseShandong Baofa.