unyango lung ithumba unyango

Unyango lweTumor yeLung: Isikhokelo esiBanzi

Eli nqaku libonelela ngesishwankathelo esibanzi unyango ithumba emiphunga iinketho, ezibandakanya izigaba ezahlukeneyo kunye neendlela. Siza kuphonononga iindlela ezahlukeneyo zonyango, sixoxe ngezinto ezinefuthe kwizigqibo zonyango, kwaye sinike ulwazi malunga nokulawula imingeni enxulumene nonyango. unyango ithumba emiphunga. Esi sikhokelo sijolise ekuxhobiseni abantu kunye neentsapho zabo ngolwazi oluyimfuneko lokuhamba kolu hambo lunzima.

Ukuqonda amathumba emiphunga

Iintlobo zamathumba emiphunga

Amathumba emiphungeni ahlelwa ngokubanzi abe ngamacandelo amabini aphambili: i-benign (engenawo umhlaza) kunye ne-malignant (umhlaza). Amathumba emiphunga anobungozi ahlulwa kwakhona abe ngumhlaza wemiphunga omncinci weseli (SCLC) kunye nomhlaza wemiphunga weseli ongeyonxalenye encinci (NSCLC). I-NSCLC yenza uninzi loxilongo lomhlaza wemiphunga. Uhlobo oluthile lwethumba emiphunga luchaphazela kakhulu unyango lung ithumba unyango isicwangciso.

Umhlaza wemiphunga

Iqonga libalulekile ekumiseleni okufanelekileyo unyango lung ithumba unyango iqhinga. Inqanaba libonisa ubungakanani bokusasazeka komhlaza. Iinkqubo zesiteji, ezifana nenkqubo ye-TNM, qwalasela ubukhulu be-tumor (T), ukubandakanyeka kwe-lymph node (N), kunye ne-metastasis ekude (M). Ukulinganisa okuchanekileyo kufuna iimvavanyo ezahlukeneyo zokuxilonga, kuquka i-imaging scans (CT, PET), i-biopsies, kunye novavanyo lwegazi.

IiKhetho zoNyango lwamathumba emiphunga

Utyando

Ukususwa ngotyando lwethumba lolona khetho lonyango lokuqala lomhlaza wemiphunga. Inkqubo ethile yotyando ixhomekeke kwindawo yethumba kunye nobukhulu. Ukhetho lubandakanya i-lobectomy (ukususwa kwe-lobe), i-segmentectomy (ukususwa kwecandelo), kunye nokususwa kwe-wedge (ukususwa kwenxalenye encinci yomphunga). Ubuchwephesha obuncinci, njengotyando lwe-thoracoscopic oluncediswa yividiyo (i-VATS), luhlala lukhethwa ukunciphisa ukuhlaselwa kunye nexesha lokubuyisela.

Unyango ngamachiza

I-Chemotherapy isebenzisa amayeza ukubulala iiseli zomhlaza. Ihlala isetyenziselwa umhlaza wemiphunga okwinqanaba eliphezulu, nokuba uwedwa okanye udityaniswe nolunye unyango. Iirejimeni ezininzi zechemotherapy ziyafumaneka, kwaye ukhetho luxhomekeke kwizinto ezahlukeneyo ezibandakanya uhlobo kunye nenqanaba lomhlaza, impilo yesigulana iyonke, kunye neziphumo ebezingalindelekanga. Iziko lomhlaza leSizwe inikeza ulwazi oluthe kratya kwiiprothokholi zechemotherapy.

Unyango ngemitha

Unyango ngemitha lusebenzisa imitha yemitha ephezulu ukujolisa kunye nokutshabalalisa iiseli zomhlaza. Ingasetyenziswa phambi kotyando (neoadjuvant), emva kotyando (adjuvant), okanye njengonyango oluphambili lwamathumba angasebenziyo. Unyango lwemitha yemitha yangaphandle lolona hlobo luxhaphakileyo. Unyango ngemitha yemitha ye-stereotactic (SBRT) luhlobo oluchane ngakumbi lonyango lwemitha olunikezela ngeedosi eziphezulu zemitha yemitha kwiiseshini ezimbalwa.

Unyango ekujoliswe kulo

Unyango ekujoliswe kulo lusebenzisa amachiza ajolise ngokukodwa kwiiseli zomhlaza ngaphandle kokonakalisa iiseli eziqhelekileyo. Olu nyango lusebenza ngokukodwa kwi-NSCLC ngokuguqulwa kofuzo oluthile. Imizekelo ibandakanya i-EGFR inhibitors, i-ALK inhibitors, kunye ne-PD-1/PD-L1 inhibitors. Uvavanyo lwemfuzo lubalulekile ukuchonga izigulane ezinokuxhamla kolu nyango lujoliswe kubo.

Immunotherapy

I-Immunotherapy idibanisa amajoni omzimba ukulwa nomhlaza. Iziyobisi ze-Immunotherapy, ezifana ne-checkpoint inhibitors, zinceda amajoni omzimba ukuba abone kwaye atshabalalise iiseli zomhlaza. Le ndlela ibonise impumelelo ebalulekileyo ekunyangeni umhlaza wemiphunga ophambili, kwaye ukusebenza kwawo kuhlala kuvavanywa ngee-biomarkers ezifana ne-PD-L1 expression.

Ukukhetha iSicwangciso soNyango esiLungileyo

Eyona ilungileyo unyango lung ithumba unyango Isicwangciso somntu ngamnye kwaye sixhomekeke kwizinto ezininzi, kubandakanya uhlobo kunye nenqanaba lethumba lemiphunga, impilo yesigulana iyonke, kunye nezinto ozikhethayo. Iqela leengcali ezininzi zonyango, kubandakanywa i-oncologists, oogqirha botyando, i-radiologists, kunye nezinye iingcali, baya kusebenzisana ukuphuhlisa isicwangciso sonyango esibanzi esilungiselelwe iimfuno zomntu ngamnye.

Ukulawula iZiphumo eziPhakamileyo kunye neNkxaso

Unyango ithumba kwimiphunga unyango kunokubangela iziphumo ebezingalindelekanga ezahlukahlukeneyo, kuxhomekeke kunyango oluthile olusetyenziswayo. Ukulawula ezi ziphumo bezingalindelekanga kubalulekile ekuphuculeni umgangatho wobomi. Amaqela enkxaso, iinkonzo zokucebisa, kunye nokhathalelo lokuthomalalisa uncedo lunokunceda kakhulu izigulane kunye neentsapho zazo ngeli xesha linzima. I Umbutho wamaLung waseMelika ibonelela ngezibonelelo ezixabisekileyo kunye nothungelwano lwenkxaso kubantu abachatshazelwe ngumhlaza wemiphunga.

UPhando kunye noTshintsho kuNyango lweTumor yeLung

Uphando oluqhubekayo luqhubela phambili ngokuqhubekayo unyango lung ithumba unyango iinketho, ezikhokelela kwiziphumo eziphuculweyo kunye nomgangatho wobomi bezigulane. Ulingo lwezonyango lubonelela ngofikelelo kunyango oluyilayo kunye negalelo kuphuhliso lonyango olutsha noluphuculweyo. Ngolwazi oluthe kratya malunga nolingo lwezonyango, ungadibana nomboneleli wakho wezempilo okanye ubhekisele kwizibonelelo ezifana ClinicalTrials.gov.

Ngolwazi oluthe kratya kunye nezikhethekileyo unyango ithumba emiphunga, Cinga ngokuqhagamshelana neShandong Baofa Cancer Research Institute e https://www.baofahospital.com/