unyango isigaba 2a unyango umhlaza wemiphunga

Inqanaba 2A Unyango lomhlaza wemiphunga: Isikhokelo esiBanzi

Inqanaba lesi-2A lomhlaza wemiphunga lifuna indlela ebanzi yonyango, elungiselelwe ngokweempawu zesigulana ngasinye. Esi sikhokelo sinika umbono weendlela ezahlukeneyo zonyango, iziphumo ebezingalindelekanga ezinokwenzeka, kunye neengqwalaselo ezibalulekileyo kwizigulana ezihamba olu xilongo lucelomngeni. Ukuqonda iindlela ezahlukeneyo zonyango kunye neenzuzo zazo ezinokubakho kunye nezinto ezithintelayo kubalulekile ekwenzeni izigqibo ezinolwazi kunye neqela lakho lezempilo.

Ukuqonda iNqanaba 2A Umhlaza wemiphunga

Inqanaba 2A umhlaza wemiphunga lithetha ukuba umhlaza usasazeke kwii-lymph nodes ezikufutshane kodwa hayi kwiindawo ezikude zomzimba. Isicwangciso sonyango oluthile luya kuxhomekeka kwizinto ezifana nobukhulu kunye nendawo yethumba, impilo yesigulane iyonke, kunye nohlobo lomhlaza wemiphunga (umzekelo, umhlaza wemiphunga weseli ongeyena omncinci (NSCLC) okanye umhlaza wemiphunga omncinci weseli (SCLC)). Ukuxilongwa kwangaphambili kunye nokuchanekileyo kubaluleke kakhulu ekusebenzeni unyango isigaba 2a unyango umhlaza wemiphunga. IZiko loPhando ngoMhlaza laseShandong Baofa ibonelela ngezakhono zokuxilonga ezikwinqanaba eliphezulu ukuqinisekisa ukucwangciswa kwezigaba ezichanekileyo kunye nezicwangciso zonyango zomntu.

IiKhetho zoNyango lweSigaba 2A soMhlaza weMiphunga

Utyando

Utyando luhlala lolona khetho luphambili lonyango lwenqanaba 2A lomhlaza wemiphunga. Uhlobo lotyando lunokwahluka ngokuxhomekeke kwindawo kunye nobukhulu bethumba. Oku kunokubandakanya i-lobectomy (ukususwa kwelobe yomphunga), i-pneumonectomy (ukususwa komphunga uphela), okanye ukususwa kwenwebu (ukususwa kwecandelo elincinane lomphunga). Iindlela zotyando ezihlaselayo zisetyenziswa rhoqo ukunciphisa ixesha lokuchacha kunye neengxaki. Ukubuyisela kwisimo sangaphambili emva kotyando kubalulekile ukuze uchache ngempumelelo. Impumelelo yotyando idla ngokuxhomekeke kwimpilo yesigulana ngasinye kunye neempawu ezithile zomhlaza wabo. IZiko loPhando ngoMhlaza laseShandong Baofa isebenzisa iindlela zotyando zangoku zokususa umhlaza wemiphunga.

Unyango ngamachiza

Unyango ngamachiza, kusetyenziswa amachiza anamandla okubulala iiseli zomhlaza, lunokusetyenziswa phambi kwe (neoadjuvant) okanye emva kotyando (i-adjuvant) ukuphucula amathuba onyango. Isenokusetyenziswa njengonyango oluphambili ukuba utyando alukho ukhetho. Iirejimeni zechemotherapy ezisetyenziswa ngokuqhelekileyo unyango isigaba 2a unyango umhlaza wemiphunga ziquka indibaniselwano yamachiza asekelwe kwiplatinam anjengecisplatin okanye i-carboplatin, kunye nezinye ii-agent ze-chemotherapy. Irejimeni ethile ye-chemotherapy iya kumiselwa ngokusekelwe kwimiba yomntu, kwaye iziphumo ezinokuthi zibekho kufuneka zixoxwe kunye ne-oncologist yakho. IZiko loPhando ngoMhlaza laseShandong Baofa ibonelela ngeenkonzo zechemotherapy ezibanzi ezixhaswa ngooncologists abanamava.

Unyango ngemitha

Unyango ngemitha lusebenzisa imiqadi enamandla kakhulu ukubulala iiseli zomhlaza. Inokusetyenziswa ngaphambi kotyando ukucutha ithumba, emva kotyando lokubulala naziphi na iiseli zomhlaza eziseleyo, okanye njengonyango lokuqala ukuba utyando alunakwenzeka. Unyango lwemitha ye-Stereotactic body radiation (SBRT) luhlobo oluchaneke kakhulu lonyango lwemitha olusa iidosi eziphezulu zemitha yemitha kwithumba ngelixa unciphisa umonakalo kwizihlunu ezisempilweni ezingqongileyo. Iziphumo ezinokubakho zonyango lwemitha ziyahluka ngokuxhomekeke kwithamo kunye nendawo yonyango.

Unyango ekujoliswe kulo

Unyango ekujoliswe kulo lusebenzisa amachiza ajolise ngokukodwa kwiiseli zomhlaza ngaphandle kokwenzakalisa iiseli ezisempilweni. Olu nyango luhlala lusetyenziswa kwizigulana ezinotshintsho oluthile lwemfuza kwiiseli zabo zethumba. Ukhetho lonyango olujoliswe kuyo luxhomekeke kakhulu kumntu ngamnye kwaye kuxhomekeke kwiziphumo zovavanyo lwemfuza yesampulu yethumba. IZiko loPhando ngoMhlaza laseShandong Baofa unokufikelela kuvavanyo oluphezulu lwe-genomic ukumisela isicwangciso sonyango esisiso.

Immunotherapy

Immunotherapy inceda amajoni omzimba ukulwa iiseli zomhlaza. Olu nyango luya lubaluleke kakhulu kwi unyango isigaba 2a unyango umhlaza wemiphunga kwaye ingasetyenziswa ngokudityaniswa nolunye unyango. I-Checkpoint inhibitors luhlobo lwe-immunotherapy oluthintela iiprotheni ezithintela amajoni omzimba ekuhlaseleni iiseli zomhlaza. Ukusebenza kwe-immunotherapy kuyahluka phakathi kwabantu.

Ukukhetha iSicwangciso soNyango esiLungileyo

Isicwangciso sonyango esingcono kakhulu unyango isigaba 2a unyango umhlaza wemiphunga kumiselwa ngengxoxo yentsebenziswano phakathi kwesigulana kunye neqela labo lezempilo. Eli qela libandakanya i-oncologist, ugqirha we-thoracic, i-radiation oncologist, kunye nezinye iingcali njengoko kufuneka. Izinto eziqwalaselwayo ziquka iminyaka yomguli, impilo yakhe iyonke, uhlobo kunye nenqanaba lomhlaza, kunye nezinto azikhethayo. Kubalulekile ukuba uthathe inxaxheba ngokusebenzayo kule nkqubo yokwenza izigqibo kwaye ubuze imibuzo ukuqinisekisa ukuba uyaziqonda ngokupheleleyo iinketho zonyango kunye neengozi zabo kunye neenzuzo zabo.

I-Prognosis kunye neNkathalo yexesha elide

Ingqikelelo yenqanaba 2A lomhlaza wemiphunga iyaguquguquka kwaye ixhomekeke kwizinto ezininzi, kubandakanywa uhlobo lomhlaza wemiphunga, ubungakanani kunye nendawo yethumba, kunye nempilo yonke yesigulana. Ukuqeshwa okulandelwa rhoqo kubalulekile ekubekeni iliso ekusebenzeni kwonyango kunye nokufumanisa nakuphi na ukuphindaphinda. Ukhathalelo lwexesha elide lunokubandakanya ukuhlolwa rhoqo, ukuskena kwemifanekiso, kunye nenkxaso eqhubekayo yokulawula nayiphi na imiphumo emibi yexesha elide evela kunyango. Izigulana kufuneka zigcine unxibelelwano oluvulekileyo kunye nababoneleli babo bezempilo kulo lonke uhambo lwabo lonyango.

Ukuzihlangula: Olu lwazi lololwazi jikelele kwaye aluyiyo ingcebiso yezonyango. Soloko udibana nengcali yokhathalelo lwempilo kuyo nayiphi na inkxalabo yezempilo okanye ngaphambi kokuba wenze naziphi na izigqibo ezinxulumene nempilo okanye unyango lwakho.