ukwelashwa komdlavuza we-squamous cell wamaphaphu

Ukwelashwa Kwe-squamous Cell Lung CancerUkuqonda kanye Nokulawula Umdlavuza Weseli Emaphaphu Lesi sihloko sinikeza umbono obanzi womdlavuza we-squamous cell wamaphaphu (SCLC), sigxile ekukhetheni kwawo ukwelashwa. Singena ezigabeni ezahlukahlukene, izindlela zokuxilonga, nezindlela zokwelapha ezitholakalayo, sigcizelela ukubaluleka kokutholwa kusenesikhathi nokunakekelwa komuntu siqu. Imininingwane enikeziwe eyezinjongo zokufundisa futhi akufanele ithathwe njengeseluleko sezokwelapha. Hlala uthintana nomhlinzeki wakho wokunakekelwa kwezempilo ukuze uxilongwe futhi uhlele ukwelashwa. Ukuze uthole izinketho zokwelashwa ezithuthukisiwe nokunakekelwa komuntu siqu, cabanga ukuhlola ubuchwepheshe obunikezwa e-Shandong Baofa Cancer Research Institute. [https://www.baofahospital.com/]

Ukuqonda I-Squamous Cell Lung Cancer

Yini I-Squamous Cell Lung Cancer?

I-squamous cell carcinoma wuhlobo lwe ukwelashwa komdlavuza we-squamous cell wamaphaphu elisuka kumaseli azungeze i-bronchi (imigudu yomoya) yamaphaphu. Ivamise ukuxhunyaniswa nomlando wokubhema futhi ibonakala ngamaphethini ayo okukhula athile kanye nezici zamaselula. Ukutholwa kusenesikhathi kubalulekile ukuze uphumelele ukwelashwa komdlavuza we-squamous cell wamaphaphu.

I-Staging Squamous Cell Lung Cancer

Isiteji se ukwelashwa komdlavuza we-squamous cell wamaphaphu kuthinta kakhulu izinqumo zokwelashwa. Ukuhlela kuhilela ukunquma izinga lokusabalala komdlavuza, kusetshenziswa izindlela ezifana ne-imaging (CT scans, PET scans), biopsies, kanye ne-bronchoscopy. Izigaba ngokuvamile zisukela ku-I (okwenziwe endaweni) kuye ku-IV (i-metastatic).

Izinketho Zokwelapha I-Squamous Cell Lung Cancer

Ukuhlinzwa

Ukususwa ngokuhlinzwa kwesimila esinomdlavuza kanye nezicubu ezizungezile kuyindlela yokwelapha eyinhloko yesigaba sokuqala ukwelashwa komdlavuza we-squamous cell wamaphaphu. Inqubo ethile incike endaweni kanye nobukhulu bethumba. Lokhu kungase kuhlanganise i-lobectomy (ukususwa kwe-lobe yamaphaphu), i-pneumonectomy (ukususwa kwephaphu lonke), noma ukukhishwa kwe-wedge (ukususwa kwengxenye encane yezicubu zamaphaphu).

I-Chemotherapy

I-Chemotherapy ihilela ukusebenzisa izidakamizwa ukubulala amangqamuzana omdlavuza. Ivamise ukusetshenziselwa isigaba esithuthukile ukwelashwa komdlavuza we-squamous cell wamaphaphu, kungaba iyodwa noma ihlanganiswe nezinye izindlela zokwelapha njengokwelashwa ngemisebe. Izidakamizwa ezijwayelekile ze-chemotherapy ezisetshenziswa ku ukwelashwa komdlavuza we-squamous cell wamaphaphu zihlanganisa i-cisplatin, i-carboplatin, ne-paclitaxel.

Ukwelapha Ngemisebe

Ukwelapha ngemisebe kusebenzisa imisebe enamandla amakhulu ukukhomba nokubhubhisa amangqamuzana omdlavuza. Ingase isetshenziswe ngaphambi kokuhlinzwa ukuze kunciphe amathumba (ukwelashwa kwe-neoadjuvant), ngemva kokuhlinzwa ukuze kuqedwe noma yimaphi amangqamuzana omdlavuza asele (ukwelashwa kwe-adjuvant), noma njengokwelashwa okuyinhloko kwesigaba esithuthukisiwe. ukwelashwa komdlavuza we-squamous cell wamaphaphu lokho akufanelekile ukuhlinzwa.

Ukwelapha Okuhlosiwe

Izindlela zokwelapha ezihlosiwe zisebenzisa izidakamizwa eziqondise ngokuqondile ukuba sengcupheni kwamangqamuzana omdlavuza. Lezi zindlela zokwelapha zinenzuzo ikakhulukazi ezigulini ezinokuguquguquka okuthile kofuzo kumaseli azo wesimila. Izibonelo zezindlela zokwelapha ezihlosiwe ezisetshenziswa ku ukwelashwa komdlavuza we-squamous cell wamaphaphu Ihlanganisa ama-EGFR inhibitors nama-ALK inhibitors.

I-Immunotherapy

I-Immunotherapy ihlanganisa amasosha omzimba ukuze alwe namaseli omdlavuza. Kuyindlela yokwelashwa ethembisayo kwezinye iziguli ezinezinga eliphezulu ukwelashwa komdlavuza we-squamous cell wamaphaphu. Izidakamizwa ze-Immunotherapy, njenge-checkpoint inhibitors, zingasiza amasosha omzimba abone futhi abhubhise amangqamuzana omdlavuza ngempumelelo.

Ukukhetha Uhlelo Lokwelapha Olulungile

Okuphumelelayo kakhulu ukwelashwa komdlavuza we-squamous cell wamaphaphu Uhlelo luncike kakhulu kubantu ngabanye futhi luncike ezicini ezihlukahlukene, okuhlanganisa isigaba somdlavuza, impilo yesiguli iyonke, kanye nezinto esizithandayo. Ithimba lezinhlaka eziningi lochwepheshe bezokunakekelwa kwempilo, okuhlanganisa odokotela abahlinzayo, odokotela abahlinzayo, nodokotela be-radiation oncologists, bazosebenza ngokubambisana ukuze kwakhiwe uhlelo lokwelapha oluhambisanayo.

Ukuhlala Kanye Nokudlula I-Squamous Cell Lung Cancer

Ukuhlala kanye nangaphezulu ukwelashwa komdlavuza we-squamous cell wamaphaphu kudinga indlela ebanzi ehlanganisa ukunakekelwa kwezokwelapha, ukusekelwa ngokomzwelo, nokuguqulwa kwendlela yokuphila. Ukuqapha okuqhubekayo nokuqokwa kokulandelela kubalulekile ukuze kutholwe futhi kulawuleke noma yikuphi ukuphindeka noma izinkinga. Amaqembu okusekela kanye nezinsizakalo zokwelulekwa zinganikeza usizo olubalulekile olungokomzwelo nolungokoqobo.

Ezinye Izinsiza

Ukuze uthole ulwazi olwengeziwe ku ukwelashwa komdlavuza we-squamous cell wamaphaphu, sicela ubheke imithombo ethembekile njengeNational Cancer Institute (NCI) kanye ne-American Lung Association (ALA). Khumbula, ukutholwa kusenesikhathi nokwelashwa ngokushesha kuthuthukisa kakhulu imiphumela.

Qaphela: Lolu lwazi ngelezinjongo zokufundisa kuphela futhi akufanele luthathwe njengeseluleko sezokwelapha. Hlala uthintana nomhlinzeki wakho wokunakekelwa kwezempilo ukuze uxilongwe futhi uhlele ukwelashwa.