isigaba sokwelashwa 3 Ukwelashwa komdlavuza wamaphaphu okungewona amangqamuzana amancane Izibhedlela

Izinketho Zokwelapha Zesigaba 3 Umdlavuza Ongewona Owomncane Weseli Wamaphaphu (NSCLC)

Isigaba 3 somdlavuza wamaphaphu ongewona omncane (NSCLC) siwukuxilongwa okungathi sína, kodwa intuthuko ekwelashweni inikeza ithemba. Lo mhlahlandlela unikeza ukubuka konke okutholakalayo isigaba sokwelashwa 3 Ukwelashwa komdlavuza wamaphaphu okungewona amangqamuzana amancane Izibhedlela kanye nezinketho zokwelapha, okugcizelela ukubaluleka kokunakekelwa komuntu siqu kanye nokufuna iseluleko sezokwelapha esichwepheshile. Ukuqonda uhlelo lwakho lokwelapha kubalulekile ukuze uzulazule kulolu hambo oluyinselele. Lolu lwazi olwezinjongo zemfundo kuphela futhi akufanele luthathe indawo yeziqondiso zezokwelapha ezichwepheshile.

Ukuqonda Isigaba 3 NSCLC

Isigaba sesi-3 se-NSCLC sihlukaniswa ngeSigaba IIIA kanye ne-IIIB, okubonisa izinga lokusabalala komdlavuza. Isigaba IIIA sibandakanya ukusabalala komdlavuza kuma-lymph node aseduze, kuyilapho iSigaba IIIB sihlanganisa ukubandakanyeka okubanzi kwama-lymph node kanye/noma ukusabalala ezakhiweni eziseduze. Indlela yokwelapha ethize izoncika ezintweni ezimbalwa, okuhlanganisa isigaba esinembile, impilo yesiguli iyonke, kanye nezici zesimila (njengofuzo kanye nephrofayili yamangqamuzana).

Izinketho Zokwelashwa Zesigaba 3 NSCLC

Ukuhlinzwa

Kwezinye iziguli ezine-Stage 3 NSCLC, ukuhlinzwa kungase kube inketho, okungenzeka kuhilele ukususwa kwesimila nama-lymph nodes azungezile. Ukuba nokwenzeka kokuhlinzwa kuncike endaweni kanye nosayizi wesimila kanye nempilo yonke yesiguli. Izinketho zokuhlinzwa zingabandakanya i-lobectomy (ukususwa kwe-lobe yamaphaphu) noma i-pneumonectomy (ukususwa kwephaphu lonke). Ukunakekelwa kwangemva kokuhlinzwa kubalulekile ukuze umuntu alulame.

I-Chemotherapy

I-Chemotherapy isebenzisa imithi ukubhubhisa amangqamuzana omdlavuza. Ivamise ukusetshenziswa ngaphambi kokuhlinzwa (i-neoadjuvant chemotherapy) ukunciphisa isimila, okwenza ukuhlinzwa kuphumelele kakhulu, noma ngemva kokuhlinzwa (i-adjuvant chemotherapy) ukuze kuqedwe noma yimaphi amaseli omdlavuza asele. Kunezinhlobo ezahlukene zemithi yokwelapha ngamakhemikhali, eyenzelwe izidingo zesiguli ngasinye. Imiphumela engemihle ivamile futhi iyahlukahluka kuye ngemithi ethile esetshenzisiwe.

Ukwelapha Ngemisebe

Ukwelapha ngemisebe kusebenzisa imisebe enamandla amakhulu ukukhomba futhi kubulale amangqamuzana omdlavuza. Ingasetshenziswa iyodwa noma ihlanganiswe nezinye izindlela zokwelapha. Ukwelashwa ngemisebe ye-beam yangaphandle kuvame ukusetshenziswa, kuqondise imisebe ephuma ngaphandle komzimba iye endaweni yesimila. Ukwelashwa ngemisebe kungaba nemiphumela engemihle, okuhlanganisa ukukhathala nokucasuka kwesikhumba.

Ukwelapha Okuhlosiwe

Imithi yokwelapha ehlosiwe igxila kuma-molecule athile ngaphakathi kwamangqamuzana omdlavuza, avimbele ukukhula nokusabalala kwawo. Lezi zindlela zokwelapha zivame ukusetshenziswa lapho izinguquko ezithile zofuzo zikhona esimila. Ukusebenza kokwelashwa okuqondisiwe kuncike kuphrofayili yofuzo lwesimila. Ukuqapha njalo kuyadingeka ukuze kuhlolwe ukusebenza kokwelashwa nokulawula noma yimiphi imiphumela emibi engase ibe khona.

I-Immunotherapy

I-Immunotherapy isiza amasosha omzimba ukulwa namaseli omdlavuza. Isebenza ngokukhulisa amandla amasosha omzimba okubona nokuhlasela amangqamuzana omdlavuza. Imithi eminingi ye-immunotherapy iyatholakala, ngayinye inezindlela ezithile zokwenza. I-Immunotherapy ingaveza izimpendulo ezihlala isikhathi eside kodwa ingaba nemiphumela engemihle edinga ukuqapha okuseduze.

Ukukhetha a Ukwelashwa Isigaba 3 Izibhedlela Ezingezona Ezincane Zokwelapha Umdlavuza Wamaphaphu

Ukukhetha isibhedlela esifanele kubalulekile. Cabangela izici ezinjengokuhlangenwe nakho kwesibhedlela ekwelapheni umdlavuza wamaphaphu, ubuchwepheshe bodokotela baso bomdlavuza nodokotela abahlinzayo, ukufinyelela kubuchwepheshe bokwelapha obuthuthukisiwe (njengokuhlinzwa kwerobhothi noma amasu athuthukisiwe emisebe), kanye nokuba khona kwezinsizakalo zokweseka eziphelele. Ukubuyekezwa kwesiguli nezincomo ezivela kwezinye iziguli nakho kungabaluleka.

I I-Shandong Baofa Cancer Research Institute iyisikhungo esihamba phambili esizinikele ekuhlinzekeni ukunakekelwa komdlavuza wesimanje. Ukuzibophezela kwabo ekunakekelweni okugxiliswe esigulini, kuhlanganiswe nobuchwepheshe bezokwelapha obuthuthukile, kubenza babe insiza ebalulekile kubantu ababhekene nale nselele.

Ukucatshangelwa Okubalulekile

Kubalulekile ukukhumbula ukuthi uhambo lomdlavuza womuntu ngamunye luhlukile. Izinhlelo zokwelapha zenzelwe izimo zomuntu ngamunye, futhi ukuxhumana okuvulekile nethimba lakho lezempilo kubalulekile. Ungalokothi ungabaze ukubuza imibuzo, ukuveza okukukhathazayo, futhi ubambe iqhaza ngenkuthalo ekwenzeni izinqumo mayelana nokwelashwa kwakho. Amaqembu okusekela kanye nezinsizakalo zokwelulekwa zinganikeza ukusekelwa okubalulekile ngokomzwelo nokusebenzayo.

Umshwana wokuzihlangula: Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi akufanele luthathwe njengeseluleko sezokwelapha. Hlala uthintana nochwepheshe bezempilo ukuze uxilongwe futhi ulashwe noma yisiphi isimo sezempilo.