chithandizo siteji 3 sanali yaing'ono cell khansa ya m'mapapo chithandizo

Njira Zochizira M'gawo Lachitatu Khansa Yam'mapapo Yosakhala Yaing'ono

Gawo 3 la khansa ya m'mapapo yopanda yaying'ono (NSCLC) imakhala ndi zovuta zapadera, zomwe zimafunikira njira zosiyanasiyana zochizira. Bukuli likuwunikira njira zosiyanasiyana zochizira, kufotokoza momwe angagwiritsire ntchito bwino, zotsatirapo zake, komanso kuyenera kutengera momwe wodwalayo alili. Kumvetsetsa zosankhazi ndikofunikira kuti mupange zisankho mwanzeru pamodzi ndi oncologist wanu.

Kumvetsetsa Gawo 3 NSCLC

Gawo 3 NSCLC lagawidwa mu Gawo IIIA ndi IIIB, kuwonetsa kukula kwa khansa. Gawo la IIIA limakhudza khansa yomwe yafalikira ku ma lymph node oyandikana nawo, pomwe Gawo IIIB limakhudza kukhudzidwa kwa ma lymph node komanso / kapena kufalikira kumagulu oyandikana nawo. Kujambula molondola kudzera mu kujambula (CT scans, PET scans) ndi biopsies ndizofunikira kwambiri kuti mudziwe zoyenera kwambiri. chithandizo siteji 3 sanali ang'onoang'ono cell khansa ya m'mapapo chithandizo dongosolo.

Njira Zochiritsira za Gawo 3 NSCLC

Opaleshoni

Opaleshoni ikhoza kukhala mwayi wosankha odwala a Gawo IIIA omwe ali ndi vuto lochepa la nodal komanso thanzi labwino. Izi zingaphatikizepo lobectomy (kuchotsa mapapu) kapena pneumonectomy (kuchotsa mapapu onse). Kuchotsa opaleshoni nthawi zambiri kumatsatiridwa ndi adjuvant therapy (chemotherapy kapena radiation) kuti achepetse chiopsezo chobwereza. Chigamulo chopitiriza opaleshoni chimadalira zinthu zingapo, kuphatikizapo malo ndi kukula kwa chotupacho, thanzi la wodwalayo, ndi kukula kwa ma lymph node. Shandong Baofa Cancer Research Institute imapereka ukadaulo wokwanira wa opaleshoni ya khansa ya m'mapapo.

Chemotherapy

Chemotherapy, kugwiritsa ntchito mankhwala amphamvu kuti aphe maselo a khansa, ndizofala chithandizo siteji 3 sanali ang'onoang'ono cell khansa ya m'mapapo chithandizo kwa Gawo IIIA ndi IIIB NSCLC. Ma regimen amasiyana kutengera momwe zinthu ziliri, ndipo zingaphatikizepo mankhwala opangidwa ndi platinamu (cisplatin kapena carboplatin) ophatikizidwa ndi othandizira ena monga pemetrexed kapena docetaxel. Chemotherapy ikhoza kuperekedwa musanachite opaleshoni (neoadjuvant) kuti muchepetse chotupacho, pambuyo pa opaleshoni (adjuvant) kuchotsa maselo a khansa otsala, kapena ngati chithandizo choyambirira. Zotsatira zake zimakhala zofala ndipo zingaphatikizepo nseru, kutopa, ndi tsitsi; komabe, izi nthawi zambiri zimatha kuyendetsedwa ndi chithandizo chothandizira.

Chithandizo cha radiation

Chithandizo cha radiation chimagwiritsa ntchito cheza champhamvu kwambiri kuti chiwononge maselo a khansa. Itha kugwiritsidwa ntchito yokha kapena kuphatikiza ndi chemotherapy. Chithandizo cha radiation chingagwiritsidwe ntchito musanachite opaleshoni (neoadjuvant) kuti achepetse chotupacho, pambuyo pa opaleshoni (adjuvant) kuti ayang'ane maselo a khansa omwe atsala, kapena ngati chithandizo choyambirira, makamaka kwa odwala omwe sali okonzekera opaleshoni. Stereotactic body radiation therapy (SBRT) ndi mtundu wolondola wa radiation womwe umapereka milingo yayikulu ya radiation ku chotupacho ndikusunga minofu yathanzi yozungulira. Mitundu yeniyeni ndi mlingo wa chithandizo cha radiation zimadalira momwe munthuyo alili.

Chithandizo Chachindunji

Thandizo loyang'aniridwa limagwiritsa ntchito mankhwala omwe amayang'ana kwambiri ma cell a khansa kutengera masinthidwe awo. Kusintha kwina kwa ma genetic (monga EGFR, ALK, ROS1 masinthidwe) ndizofala mu NSCLC ndipo zitha kuneneratu kuyankha kwamankhwala omwe akutsata. Ngati kusinthika koteroko kuzindikirika, chithandizo chomwe mukufuna chingakhale mwala wapangodya chithandizo siteji 3 sanali ang'onoang'ono cell khansa ya m'mapapo chithandizo, zomwe zingapereke zotsatira zabwino komanso zotsatirapo zochepa poyerekeza ndi mankhwala achikhalidwe. Katswiri wanu wa oncologist adzayesa ma genetic kuti adziwe ngati chithandizo chomwe mukufuna ndi choyenera kwa inu.

Immunotherapy

Immunotherapy imagwiritsa ntchito mphamvu ya chitetezo cha mthupi kulimbana ndi khansa. Ma Immune checkpoint inhibitors, monga nivolumab kapena pembrolizumab, amagwiritsidwa ntchito kuletsa mapuloteni omwe amalepheretsa chitetezo chamthupi kuukira maselo a khansa. Immunotherapy nthawi zambiri imagwiritsidwa ntchito limodzi ndi chemotherapy ndipo ikhoza kukhala njira kwa odwala omwe ali ndi mbiri yeniyeni kapena omwe sanayankhe bwino pamankhwala ena. Zotsatira zake zimakhala zotheka ndipo zimasiyana malinga ndi mankhwala enieni.

Kusankha Njira Yoyenera ya Chithandizo

Mulingo woyenera kwambiri chithandizo siteji 3 sanali ang'onoang'ono cell khansa ya m'mapapo chithandizo njira zimadalira zinthu zingapo, kuphatikizapo siteji ya khansa, wodwala wonse thanzi, ndi kukhalapo kwa enieni masinthidwe chibadwa. Gulu losiyanasiyana la akatswiri a oncologists, maopaleshoni, ndi othandizira ma radiation adzagwira ntchito limodzi kuti apange dongosolo lachithandizo lamunthu. Kulankhulana momasuka ndi wothandizira zaumoyo wanu ndikofunikira kuti mumvetsetse zomwe mungasankhe ndikusankha bwino za chisamaliro chanu.

Izi ndi zongophunzitsa zokha ndipo siziyenera kutengedwa ngati upangiri wachipatala. Nthawi zonse funsani ndi wothandizira zaumoyo wanu kuti mudziwe ndi kuchiza matenda aliwonse.

Chodzikanira: Izi ndi zongodziwitsa anthu komanso kudziwa zambiri zokha, ndipo sizikupanga upangiri wamankhwala. Ndikofunikira kukaonana ndi dokotala wodziwa bwino za thanzi lanu kapena musanapange zisankho zokhudzana ndi thanzi lanu kapena chithandizo chanu. Zomwe zaperekedwa pano siziyenera kutengedwa ngati m'malo mwa upangiri wachipatala, matenda, kapena chithandizo.