UMIPIC Therapy - Shandong Baofa Oncotherapy Corporation Limited

Slow Release Depot Therapy

Ultra Minimum Incision Personalized Intra-Tumoral Chemo-Immuno Therapy

Mankhwala oletsa khansa omwe amapangidwa ndi kuphatikiza kwa kumasulidwa kosalekeza, mankhwala a chemotherapy (mankhwala apawiri), ndi chitetezo cha mthupi amalowetsedwa mwachindunji mu chotupacho ndikulowetsedwa mu chotupa motsogoleredwa ndi CT, ultrasound, kapena endoscopy. Mankhwala oletsa khansa amamasulidwa pang'onopang'ono mkati mwa masiku 7-20, kupha maselo a khansa, kupeŵa zotsatira za poizoni za mankhwala pa thupi lonse ndi kukwaniritsa cholinga chochotsa chotupacho; The self tumor antigens otulutsidwa ndi ma cell a khansa omwe amaphedwa ndi mankhwala ophatikizika nthawi imodzi, mothandizidwa ndi ma adjuvants a chitetezo chamthupi, amathandizira kuyankha kwa chitetezo chamthupi, potero amatenga nawo gawo pakuchotsa ma cell a khansa omwe amabwereranso kapena metastatic. Kupha kolunjika komwe kumayang'ana kupha ndikuchotsa mutu kumatha kuchitidwa chifukwa cha zotupa zowopsa komanso zotupa za metastatic m'malo osiyanasiyana a thupi, oyenera zotupa zolimba zoyambirira, zapakati, komanso mochedwa m'mbali zonse za thupi. Chithandizochi chapeza matekinoloje ovomerezeka ku China, United States, ndi Australia. Chiyambireni ntchito yake mu 1998, yathandiza odwala khansa opitilira 80000 ndipo yapeza zotsatira zabwino zamankhwala!

Chothandizira chathu chachikulu ndikuti chithandizo chamankhwala chokhazikika chimagwirizanitsa ubwino wa chemotherapy ndi immunotherapy, ndipo kwa nthawi yoyamba, awiriwa aphatikizidwa ndikugwiritsidwa ntchito ku intratumoral therapy kupyolera mwa kuchitapo kanthu. Zimagwirizanitsa chithandizo cham'deralo ndi padziko lonse lapansi, ndikuwonjezera ndende ndi nthawi ya mankhwala pogwiritsa ntchito kumasulidwa kosalekeza kwa mankhwala mkati mwa chotupacho, chomwe sichimangokhala ndi zotsatira za anticancer m'deralo za mankhwala amphamvu a chemotherapy, komanso amaganiziranso ntchito ya systemic immunotherapy, motero kupanga zofooka za njira zina zochiritsira, kupereka malingaliro atsopano ndi njira zothandizira khansa, makamaka zotupa zapakati ndi zapamwamba, makamaka kuchepetsa ndi kuchepetsa chotupa. kuletsa chotupa Kusamutsa kuli ndi phindu lofunika kwambiri; Chithandizo cha UMPIC chili ndi mwayi wogwiritsa ntchito chotupa ngati gwero la antigen komanso katemera wa autologous, zomwe zimagwirizananso ndi kakulidwe ka Personalized Medicine. Ndipo amagwiritsidwa ntchito ku chipatala, hapten pamodzi ndi mankhwala a chemotherapy kuti apitirize kutulutsidwa kwa chithandizo cha khansa ya pancreatic, pamene akuthandizira zotsatira za distal, zomwe zimachititsa kuti chitetezo cha mthupi chitetezeke, T-cell zokhudzana ndi CD4, CD8, DC, T ndi NK maselo, ndi B-cell zokhudzana ndi chotupa autoantibodies: Antibodies to P53, P16, Cmyc, Zeta IMP1, Koc, Survivin, p62, HCC1 ndi ma oncogenes ena, aka ndi nthawi yoyamba kupeza kuti T ndi B akukhudzidwa ndi kuyankha kwa chitetezo chamthupi, komanso ntchito zachipatala za distal effect ndipo chithandizochi chinasankhidwa kuti "Clinical Operation Guidelines for Interventional Treatment of Advanced Pancreatic Cancer" (Trial) (7th edition by the Chinese Medical Center for the Chinese Researching for the Medical Center for the Medical Center for the Chinese Research and the Anti-Formulated Association of Medical Center ndi Therapy, ndi National Interventional Medicine Innovation Alliance inasindikizidwa pa

Journal of Clinical Radiology, voliyumu 43, nambala 19, 2024, 1636-1648.

Dr.Baofa Yu ndi gulu lake zokonda zofufuza zomwe zidaphatikizapo izi:

1.Zotupa zazing'ono zakutali zimatha kuwongoleredwa, ndi umboni ndi zolemba;

2.Kuyang'ana kwa subclinical kumatha kuwongoleredwa, kotero kuti nthawi yopulumuka ya odwala ndi yayitali;

3.Imachepetsanso ma cell chotupa ozungulira (CTC) ndi 80%, nkhani yomwe iyenera kusindikizidwa;

4.Ikhoza kulimbikitsa hypothalamus ya ubongo kuti itenge nawo mbali pachitetezo cha chitetezo cha mthupi, ndipo panthawi imodzimodziyo, imathanso kusunga chisangalalo cha ubongo ndi nyimbo kuti zigwirizane ndi zotsutsana ndi khansa. Nkhaniyi yamalizidwa, ndipo pulofesa wa UCSD akuwonetsa kuti apereke ku chilengedwe kapena mankhwala achilengedwe.

UMIPIC-Therapy: Mankhwala amtundu wa mankhwala

Adjuvant: kuwonjezeka kwa immunological reaction komanso mwachindunji
Sustaining agent: kusunga zonse pamalo okwera kwa nthawi yayitali
Antitumor agents: Malamulo ovomerezeka a FDA anachititsa kuti chotupa chizifa kuti chitulutse ma antigen kuti chisawuma.

Ubwino waukulu zisanu ndi chimodzi wa Slow Release Depot Therapy: kulunjika pang'ono, kuchotsedwa kwa chotupa, kutsekeka kwa chitetezo chamthupi, katemera wochulukirachulukira, wokhalitsa, wotetezeka komanso wogwira mtima.

Ubwino pamasamba angapo a interception chotupa
(1) Tumoricidal Interception pa malo oyambirira a chotupa: pansi pa CT kapena ultrasound guiding, malingana ndi kukula kwa chotupa, mukhoza kubaya mlingo woyenera wa mankhwala osakaniza.
(2) Kupititsa patsogolo mankhwala oletsa khansa: oxidant inachititsa kuti chotupacho chikhale chotupa kuti chigwire mankhwalawa kwa nthawi yayitali ndikuchita bwino.
(3) Kuthamangitsidwa kwa Immunological: kuchotsa chotupa chachikulu panthawiyi kumapangitsa kuti chitetezo cha mthupi chitetezeke chotupa pa malo achiwiri a chotupacho.
(4) Autologous angapo chotupa ma antigen : chotupa kugwirizana ma antigen ndi gwero la haptenation ndi katemera: yeniyeni autologous antigen, ma antigen enieni angapo ndi antigen kwenikweni payekha.
(5) Yosavuta kugwiritsa ntchito: Imatha kuchiza chotupa choyambirira komanso imatha kuchiza chotupa chachiwiri komanso kupangitsa kuti munthu asadwale matenda.
(6) Zotetezeka komanso zothandiza.

UMPIC Therapy

Slow Release Depot Therapy

Ultra Minimum Incision Personalized Intra-Tumoral Chemo-Immuno Therapy

UMIPIC-Therapy: Mankhwala amtundu wa mankhwala

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