Kurekura Kuramba Kumiti yo Gutanga Ibiyobyabwenge: Incamake Yuzuye 

Kurekura Kuramba Kumiti yo Gutanga Ibiyobyabwenge: Incamake Yuzuye

Iyi ngingo itanga ibisobanuro birambuye bya gukomeza kurekura imiti itanga imiti, gucukumbura uburyo bwayo, inyungu, porogaramu, hamwe nicyerekezo kizaza. Tuzacengera muri sisitemu zitandukanye zo kubyara, dukemure ibyiza byabo n'imbogamizi, tunasuzume ingaruka ku musaruro w'abarwayi n'ibiciro by'ubuvuzi. Amakuru yatanzwe agenewe abashaka gusobanukirwa byimbitse niki gice cyingenzi cyiterambere ryimiti no kuvura.

Uburyo bwo Kurekura Kuramba Gutanga Ibiyobyabwenge

Kugenzura Kurekura Uburyo

Kurekura kuramba kuvura imiti yishingikiriza ku buryo butandukanye bwo kugenzura igipimo ibiyobyabwenge bisohoka mu mubiri. Harimo sisitemu igenzurwa na diffuzione, aho ibiyobyabwenge bitandukana binyuze muri materique polymeric; sisitemu igenzurwa nisuri, aho ibiyobyabwenge bisohoka nkuko polymer yangirika; pompe ya osmotic, ikoresha umuvuduko wa osmotic kugirango ibiyobyabwenge bisohore. Guhitamo uburyo biterwa nibiyobyabwenge hamwe numwirondoro wo kurekura.

Ibinyabuzima bishobora kwangirika

Benshi uburyo burambye bwo gutanga ibiyobyabwenge koresha polymers ya biodegradable nka poly (acide lactique-co-glycolike) (PLGA) na poly (caprolactone) (PCL). Izi polymers zitanga ibyiza byinshi, harimo biocompatibilité no kugabanuka kwangirika, biganisha ku kurekura ibiyobyabwenge. Nyamara, imbogamizi ziracyari mugutezimbere polymer kubintu byihariye byo gutanga ibiyobyabwenge. Guhitamo polymer ikwiye ningirakamaro mugushikira ibyifuzo byo kurekura no kugabanya ingaruka mbi.

Gushyira mu bikorwa Kurekura Kurekura Gutanga Ibiyobyabwenge

Ubuvuzi bwa Kanseri

Kurekura burundu gutanga ibiyobyabwenge igira uruhare runini mu kuvura kanseri. Mugutanga imiti ya chimiotherapeutique mugihe kinini, ubu buryo bugabanya inshuro zubuyobozi, bugabanya ingaruka mbi, kandi bunoze kubahiriza abarwayi. Ingero zirimo uburyo bwo gutanga ibiyobyabwenge byatewe no kuvura ibibyimba byaho hamwe na nanoparticles yo gutanga imiti igamije.

Ubuvuzi bwa Hormone

Ubuvuzi bwo gusimbuza imisemburo akenshi bungukirwa irekurwa rirambye. Ibi bigabanya ihindagurika ryurwego rwa hormone, biganisha ku kunoza imikorere ningaruka nke ugereranije nubuvuzi busanzwe bwo mu kanwa cyangwa inshinge. Ibi birakenewe cyane cyane kubuvuzi busaba imisemburo ihamye mugihe kirekire.

Ibindi Porogaramu

Kurenga kanseri hamwe no kuvura imisemburo ya hormone, gukomeza kurekura ibiyobyabwenge ikoreshwa mubice bitandukanye byo kuvura, harimo gucunga ububabare (urugero, opioide yaguye-irekura), indwara zifata umutima (urugero, anti-hypertensives ikomeza-kurekura), hamwe nubuvuzi bwamaso (urugero, ibitonyanga bikomeza kurekura amaso). Ubwinshi bwubu buryo butuma bukenerwa muburyo butandukanye bwo kuvura.

Ibyiza nibibi byo Kurekura Kuramba Gutanga Ibiyobyabwenge

Imbonerahamwe ikurikira irerekana muri make ibyiza byingenzi nibibi bya gukomeza kurekura imiti itanga imiti:

Icyerekezo kizaza muburyo burambye bwo kurekura ibiyobyabwenge

Ubushakashatsi bukomeje gutera imbere gukomeza kurekura imiti itanga imiti. Mu bice byibandwaho harimo guteza imbere polimeri nshya y’ibinyabuzima ishobora kunonosorwa neza kandi ikagenzura imyirondoro y’imyororokere, guhuza uburyo bwo gufata amashusho buhanitse bwo gukurikirana irekurwa ry’ibiyobyabwenge muri vivo, hamwe no gushushanya uburyo bwo gutanga imiti itera imiti irekura ibiyobyabwenge hasubijwe ibimenyetso byihariye bya physiologique.

Ukeneye ibisobanuro birambuye kubyerekeye ubushakashatsi bwa kanseri no kuvura, tekereza gusura Shandong Baofa Ikigo Cyubushakashatsi cya Kanseri urubuga.

¹Amakuru arashobora gutandukana bitewe na sisitemu yihariye yo gutanga no gutanga. Nyamuneka saba ibitabo bya siyansi bijyanye nibicuruzwa bijyanye namakuru arambuye.