Ukukhutshwa okuzinzileyo kweziyobisi unyango lonyango: Ushwankathelo olubanzi 

Ukukhutshwa okuzinzileyo kweziyobisi unyango lonyango: Ushwankathelo olubanzi

Eli nqaku libonelela ngenkcukacha eneenkcukacha ze Ukukhutshwa okuzinzileyo kweziyobisi, ehlola iindlela zayo, izibonelelo, izicelo kunye nezikhokelo ezizayo. Siza kuqhuba kwiinkqubo ezahlukeneyo zokuhambisa, ukujongana nezibonelelo kunye nokusikelwa umda, kunye nokuvavanya ifuthe kwiziphumo zesigulana kunye neendleko zokhathalelo lwempilo. Ulwazi olubonisiweyo lwenzelwe abo bafuna ukuqonda okunzulu kule ndawo ibalulekileyo kuphuhliso lwamayeza kunye nonyango.

Iindlela zokukhutshwa kweziphoso ezizinzileyo

Iindlela zolawulo ezilawulwayo

Ukukhutshwa okuzinzileyo kweziyobisi ixhomekeke kwiindlela ezahlukeneyo ukulawula inqanaba apho ichiza likhutshwe khona emzimbeni. Oku kubandakanya iinkqubo ezilawulwa ngokwahlukileyo, apho ichiza lingahluka khona nge-polymeric matrix; iinkqubo ezilawulwa-zilawulwa, apho ichiza likhutshwa khona njengoko i-polymer ithoba; kunye neempompo ze-osmotic, ezisebenzisa uxinzelelo lwe-OSMOIC lokuqhuba ukukhutshwa ngamachiza. Ukukhetha indlela yendlela kuxhomekeke kwiipropathi zeziyobisi kunye neprofayili yokukhuphela imfuneko.

Iipolymers ezinobungozi

Ezininzi Ukukhutshwa okuzinzileyo kweziyobisi Sebenzisa i-billgraphid bioders njenge-poly (i-lactic-vlycolic acid) (PLGA) (PLGA) kunye ne-poly (i-caprolactor) (PCL). Ezi polimers zinika izibonelelo ezininzi, kubandakanya nokucoca i-biomity kunye nokupheliswa okulawulwayo, kukhokelela ekukhutshelwe ngokukhululekileyo kweziyobisi. Nangona kunjalo, imiceli mngeni ihlala ixhasa iipropathi zePolymer yezicelo ezithile zokuhambisa iziyobisi. Ukukhethwa kwe-polymer efanelekileyo kubalulekile ekufezekiseni ii-kinetics zokukhutshwa okufuneka kwaye kuncitshiswe iziphumo ezibi.

Izicelo zoCwangciso lweZiyobisi eziZinzileyo

Unyango lomhlaza

Ukukhutshwa kweziphoso ezinzileyo Idlala indima ebalulekileyo kunyango lomhlaza. Ngokuhambisa iiarhente zokucoca i-chemotheutic ixesha elingangexesha elide, le ndlela inciphisa imvakanyo yolawulo, inciphise iziphumo ebezingalindelekanga, kwaye iphucule ukuthotyelwa kwesigulana. Imizekelo ibandakanya iinkqubo zokuhambisa iziyobisi ezinokuhanjiswa kweziyobisi zonyango lwe-tumations yendawo kunye ne-nanopargarcles yokuhanjiswa kweziyobisi.

I-hormone yokutshintsha konyango

I-hormone yokutshintsha i-PHOPRAPUP ihlala izibonelelo Ifomu yokukhutshwa okuzinzileyo. Oku kunciphisa ukuguquguquka kumanqanaba e-hormone, kukhokelela ekuphuculeni ukusebenza kakuhle kunye neziphumo ezininzi eziphezulu ngokuthelekiswa neendlela eziqhelekileyo zomlomo okanye eziqinisekileyo. Oku kufanelekile kunyango olufuna amanqanaba amahomo ozinzileyo ixesha elide.

Ezinye iinkqubo

Ngaphaya komhlaza kunye ne-hormone yokutshintsha kwe-hormone yokutshintsha, Ukukhutshwa kweziphoso ezinzileyo isetyenziswa kwiindawo ezahlukeneyo zonyango, kubandakanya ulawulo lweentlungu (umzekelo. Ukusetyenziswa kwezi ndlela kuyenza ilungele uluhlu olubanzi lweemfuno zonyango.

Izibonelelo kunye nokungalunganga kokukhutshwa kweziyobisi

Itheyibhile engezantsi ishwankathela izibonelelo ezibalulekileyo kunye nezinto eziluncedo Ukukhutshwa okuzinzileyo kweziyobisi:

Izikhombisi zexesha elizayo zokukhutshwa kweziyobisi

Uphando luyaqhubeka ukuqhubela phambili Ukukhutshwa okuzinzileyo kweziyobisi. Iindawo ekugxilwe kuzo zibandakanya ukuphuculwa kwee-billymes ezintsha ezinokuphuculwa kunye neeprofayili zokupheliswa kwengqondo, ukudityaniswa kweendlela eziphambili zokuhambisa iziyobisi kwi-VIV, kunye noyilo lweenkqubo zokuhambisa iziyobisi ezikhuthazayo zokuphendula iziyobisi.

Ngolwazi oluthe kratya ngophando lomhlaza kunye nokhetho lonyango, jonga ukutyelela i IZiko loPhando lweShandong Baeo iwebhusayithi.

¹Idatha inokuhluka ngokuxhomekeka kwinkqubo ethile kunye nenkqubo yokuhambisa esetyenzisiweyo. Nceda ujonge uncwadi lwesayensi ofanelekileyo kunye nolwazi lwemveliso yedatha eneenkcukacha.