Ukuqonda iinkqubo zokuhambisa iziyobisi 

Ukuhanjiswa kweziyobisi ekujoliswe kuzo Le ndlela iphucula kakhulu ukusebenza konyango kwaye inciphisa iziphumo ezibi ezihambelana ne-chemotherapy ye-chemotherapy. Esi sikhokelo siphonononga iindlela ezahlukeneyo, izibonelelo, imiceli mngeni, kunye nethemba elizayo Ukuhanjiswa kweziyobisi ekujoliswe kuwo kuMhlaza.

Ukuqonda iinkqubo zokuhambisa iziyobisi

Isidingo sokuchaneka

I-chemotherapy yonyango eqhelekileyo ihambisa iziyobisi ezi-anticialr kuwo wonke umzimba, ukhokelela kwityhefu yenkqubo. Ukuhanjiswa kweziyobisi ekujoliswe kuwo kuMhlazaKwelinye icala, kugxile ekunikezeleni i-arhente yonyango ngokuthe ngqo kwi-tumoor, ngaloo ndlela kuncitshiswa iziphumo ebezingalindelekanga kwaye ukwandisa ukusebenza konyango. Oku kufezekiswa ngokusebenzisa iinkqubo ezahlukeneyo zokuthwala ezijolise ngqo kwiiseli zomhlaza okanye i-tumor micronvienventions.

Iindlela zokujolisa

Izicwangciso ezininzi ziqeshwa ukufezekisa ukuhanjiswa okujolisiweyo. Oku kubandakanya: I-Antiboctor-Iyobisi (ii-ADCs): Antibodies) Ukubopha iiseli ze-tumor, ukuhambisa amachiza amacytotoxic eqhotyoshelweyo ngqo kwiiseli zomhlaza. Imizekelo iquka i-trastuzumab e-Entensine (Kadcyla) ye-herner yakhe elungileyo ye-heat kunye ne-Brentculob Ve Dotin (Adcetris) ye-Hodgkin ye-Hodgkin. Olunye uphando luyaqhubeka ekuphuculeni ukusebenza ngempumelelo kwi-ADC kunye nokunciphisa iziphumo ekujoliswe kuzo. I-LIOSOMES: Ezi zizinto ze-vesical zisebenzisa ichiza. Banokuguqulwa ngokujolisa kwi-ligands yokuphucula ubuchwephesha beeseli zomhlaza. I-Liposomal Doxoricin (Doxil) ngumzekelo oqhelekileyo, ukubonisa ingqibelelo ephuculiweyo xa kuthelekiswa neDoxorIcicin yasimahla. I-Nanoparclecles: i-nanopalicles, ezinjenge-thelymeric napticcurgaticles kunye ne-nanopartical i-nanopargaltics, tshintsha uqwalaselo kwizakhono zokulayishwa kweziyobisi kunye nokujolisa amandla. Ubungakanani babo kunye neepropathi zabo zinokulungelelaniswa ukuphucula ukuqokelelwa kwe-tumoor kunye nokukhutshwa kweziyobisi. Uphando lokusetyenziswa kwe-nanoparcloccurticals Ukuhanjiswa kweziyobisi ekujoliswe kuwo kuMhlaza Ibanzi kwaye ibandakanya ukuphonononga i-billymeds enokuhlelwa kunye ne-nanopalicals. Iivenkile zentsholongwane: Iintsholongwane zinokuba zenjini zokuhambisa izinto zemvelo, ezinje ngohlobo lonyango okanye iintsholongwane, ngokukodwa kwiiseli ze-tumer. Le ndlela iphononongwa ngonyango lwemfuza kuMhlaza.

Izibonelelo kunye nemiceli mngeni

Izibonelelo zokuhanjiswa kweziyobisi ekujoliswe kuzo

Ukwanda kokusebenza kakuhle: Uxinzelelo lweziyobisi oluphezulu kwindawo yethumba ikhokelela kwiziphumo zonyango. Ukuncitshiswa kwetyhefu yobuso: Ukuvezwa okuncinci kwezicubu ezinempilo ukuya kwichiza kuncipha iziphumo ebezingalindelekanga. Ukuphuculwa kwesigulana okuphuculweyo: Iziphumo ebezingalindelekanga zinokukhokelela ekunyamezeleni kakuhle izigulo kunye nokubambelela kwiirejimeni zonyango. Inokubakho kwiPhi iZakhono

Imiceli mngeni ekunikezelweni kweziyobisi

I-Tumor Heterogeneity: Iiseli zomhlaza ngaphakathi kwesitulo zinokukubonisa iimpawu ezahlukeneyo, zenze kube nzima ukujolisa kuzo zonke iiseli ngokufanelekileyo. Ukungena kweziyobisi: Ukufikelela kwi-tumor core kunokuba lucelomngeni ngenxa yescroma ye-turumu. Impendulo yomzimba Iindleko kunye nokwenza ububanzi beendleko: Ukuphuhliswa kokuvelisa kunye nokuvelisa iinkqubo ezijolise kuzo iziyobisi kunokubiza kakhulu.

Izikhombisi ezizayo

Uphando ngaphakathi Ukuhanjiswa kweziyobisi ekujoliswe kuwo kuMhlaza Iphononongwa ngenkuthalo iindlela ezithembisayo ezithembisayo, kubandakanya: ukudibanisa unyango: ukudibanisa ukuhanjiswa kweziyobisi kunye nolunye unyango lomhlaza, njengokunyanga okanye ukunyanga kwe-radopeap okanye radiation. Ukuphuculwa kokujolisa kwi-ligands: Ukuphuhliswa kweemolekyuli ezisebenzayo nezicwangcisiweyo. Ukukhutshwa ngamachiza aphendulayo Ukudityaniswa kweenkqubo ezahlukeneyo zokuhambisa: Ukudibanisa izibonelelo zeenkqubo ezininzi zefuthe elilinganayo.

Ukuqukumbela

Ukuhanjiswa kweziyobisi ekujoliswe kuwo kuMhlaza imele ukuqhubela phambili okubalulekileyo kunyango lomhlaza. Ngelixa imiceli mngeni ihlala, uphando oluqhubekayo kunye neenzame zophuhliso zifaka isithembiso esikhulu sokuphucula ukusebenza nokhuseleko lonyango lomhlaza. Ukudityaniswa kweendlela eziphambili zokucinga zengcinga kunye nokuqonda okuphuculweyo kwebhayoloji ye-turus kubalulekile ukuze kusebenze uyilo kunye nokusetyenziswa kwezi nkqubo. Ngolwazi oluthe kratya malunga nophando lomhlaza kunye neenketho zonyango, nceda undwendwele iZiko loPhando lwe-Shandong Baeof iwebhsayithi.Ukububanzi (ububanzi) 700px; umda: 20px auto; Ukuwa komda: Ukuwa;} th, td {umda padding: 8px; Lungelelanisayo: ishiywe;} {}