unyango lomhlaza we-squamous cell lung

Unyango lomhlaza wemiphunga kwiseli yesquamous iinketho ziyahluka ngokuxhomekeke kwinqanaba, indawo, kunye nempilo yonke yesigulane. Unyango oluqhelekileyo lubandakanya utyando, unyango lweradiation, ichemotherapy, unyango olujoliswe kuyo, kunye ne-immunotherapy. Amaxesha amaninzi, indibaniselwano yolu nyango isetyenziselwa ukufikelela esona siphumo sifanelekileyo. KwiZiko loPhando loMhlaza laseShandong Baofa, sibonelela ngeendlela zonyango oluphezulu kunye nokhathalelo lobuqu kwizigulana i-squamous cell lung cancer.Ukuqonda uMhlaza weSquamous Cell weMiphungaYintoni iSquamous Cell Lung Cancer?Umhlaza wemiphunga yeeseli zesquamous (i-SCC) luhlobo lomhlaza wemiphunga weseli engeyiyo encinci (NSCLC) osuka kwiiseli ze-squamous, ezibhityileyo, iiseli ezisicaba ezijikeleze iindlela zomoya zemiphunga. I-SCC isoloko inxulunyaniswa nembali yokutshaya kwaye ithande ukukhula kumbindi wemiphunga, kufutshane neendawo eziphambili zomoya. i-squamous cell lung cancer uyatshaya. Abanye oothunywashe abasengozini kukuchanabeka kumsi wecuba, iradon, iasbestos, neminye imichiza ethile. Imiba yemfuza kunye nembali yosapho yomhlaza wemiphunga nazo zisenokwandisa umngcipheko.Iimpawu zeSquamous Cell Lung CancerImpawu zomhlaza wemiphunga. i-squamous cell lung cancer zinokwahluka kodwa zingabandakanya: Ukhohlokhohlo oluzingisileyo Ukukhohlela igazi (hemoptysis) Intlungu yesifuba Ukuphelelwa ngumphefumlo Ukuphefumla Ukutswina Ukubetha ngomsindo ngendlela engaqondakaliyo Ukwehla kobunzima obungachazekiyo Ukudinwa Ukosuleleka ngokuphindaphindiweyo kokuphefumla, njengenyumoniya okanye ibronchitis Ukuxilongwa kweSquamous Cell Lung Cancer Ukuxilongwa i-squamous cell lung cancer ngokwesiqhelo kubandakanya indibaniselwano yovavanyo lomfanekiso kunye ne-biopsies.Uvavanyo lomfanekiso Uvavanyo lwemifanekiso eqhelekileyo lubandakanya: X-reyi yesifuba: Inokunceda ekuchongeni ubunzima obungaqhelekanga kwimiphunga. I-CT Scan (iComputed Tomography): Ibonelela ngemifanekiso eneenkcukacha ezininzi zemiphunga kunye nezicubu ezijikelezileyo. I-PET Scan (iPositron Emission Tomography): Inokunceda ekuboneni iiseli zomhlaza kuwo wonke umzimba. I-MRI (Umfanekiso weMagnetic Resonance): Ingasetyenziselwa ukuvavanya ubungakanani bomhlaza.I-BiopsyA biopsy iyimfuneko ukuze kuqinisekiswe ukuxilongwa kunye nokumisela uhlobo lomhlaza wemiphunga. Iindlela ze-Biopsy ziquka: Ibronchoscopy: Ityhubhu encinci, eguquguqukayo enekhamera ifakwe kwi-airways ukuze ibone kwaye iqokelele iisampulu zezicubu. Inaliti ye-Biopsy: Inaliti isetyenziselwa ukuqokelela iisampulu zethishu ngodonga lwesifuba. Uqhaqho lweBiopsy: Kwezinye iimeko, utyando lunokuba yimfuneko ukufumana isampulu yethishu.Unyango lweSquamous Cell Lung Cancer UkhethoIndlela yonyango ye i-squamous cell lung cancer kuxhomekeke kwizinto eziliqela, kuquka inqanaba lomhlaza, impilo yomguli, nezinto azikhethayo. Iinketho zonyango eziqhelekileyo zibandakanya utyando, unyango lwe-radiation, i-chemotherapy, unyango olujoliswe kuyo, kunye ne-immunotherapy.I-SurgerySurgery inokuba yinto ekhethiweyo ukuba umhlaza usendaweni kwaye awuzange usasazeke kwiindawo ezikude. Iinkqubo zotyando ze i-squamous cell lung cancer ziquka: Ukususwa kweWedge: Ukususwa kwenxalenye emincinane emiphunga emiphungeni. Segmentectomy: Ukususwa kwenxalenye enkulu yomphunga. Lobectomy: Ukususwa kwelobe yonke yomphunga. Inyumoniya: Ukususwa kwawo wonke umphunga.Unyango lweRadiation TherapyRadiation isebenzisa imiqadi ene-eneji ephezulu ukubulala iiseli zomhlaza. Ingasetyenziswa njengonyango lokuqala, phambi kotyando lokunciphisa ithumba, okanye emva kotyando lokubulala naziphi na iiseli zomhlaza eziseleyo. Iindidi zonyango lwemitha ziquka: Unyango lweBeam Radiation yangaphandle (EBRT): Imitha ihanjiswa kumatshini ongaphandle komzimba. Brachytherapy: Izixhobo zokusasazeka ngemitha zibekwe ngokuthe ngqo ngaphakathi emzimbeni kufutshane nomhlaza.IChemotherapyIkhemotherapy isebenzisa amayeza ukubulala iiseli zomhlaza kuwo wonke umzimba. Ihlala isetyenziswa ngokudibanisa noqhaqho okanye unyango lweradiation. Amachiza aqhelekileyo echemotherapy i-squamous cell lung cancer ziquka i-cisplatin, i-carboplatin, i-paclitaxel, i-docetaxel, kunye ne-gemcitabine.I-Targeted TherapyTargeted zonyango amayeza ajolise kwiimolekyuli ezithile ezibandakanyekayo ekukhuleni kweeseli zomhlaza kunye nokuphila. Olu nyango luhlala lusetyenziswa kwizigulane ezineenguqu ezithile zofuzo okanye i-biomarkers. Nangona kunjalo, unyango ekujoliswe kulo lusetyenziswa ngokuqhelekileyo kwi-adenocarcinoma, olunye uhlobo lwe-NSCLC, kunokuba i-squamous cell lung cancer.ImmunotherapyImmunotherapy amayeza anceda amajoni omzimba aqaphele kwaye ahlasele iiseli zomhlaza. Olu nyango lubonise iziphumo ezithembisayo kunyango lwe i-squamous cell lung cancer. Iziyobisi eziqhelekileyo ze-immunotherapy ziquka i-pembrolizumab, i-nivolumab, kunye ne-atezolizumab.Unyango nge-StageInqanaba lomhlaza lichaphazela kakhulu isicwangciso sonyango. Ngezantsi kujongwe ngokubanzi kwiinketho zonyango ngokwenqanaba. Nceda udibane nogqirha oqeqeshiweyo kwisicwangciso sonyango lomntu. Iinketho zoNyango lweSigaba I Utyando (lobectomy okanye i-wedge resection) elandelwa yi-adjuvant chemotherapy kwezinye iimeko. Inqanaba II Utyando olulandelwa yi-adjuvant chemotherapy. Unyango ngemitha lunokuqwalaselwa ukuba utyando aluyiyo inketho. Inqanaba le-III Ukudibanisa i-chemotherapy kunye nonyango lwe-radiation. Utyando lunokuqwalaselwa kwiimeko ezikhethiweyo. I-Immunotherapy ingaba yinketho emva kwe-chemoradiation. I-Stage IV Chemotherapy, i-immunotherapy, unyango olujoliswe kuyo (ukuba lukhona), unyango lwe-radiation ukulawula iimpawu. Ukhathalelo lwePalliative ukuphucula umgangatho wobomi. Ulingo lwezonyangoUlingo lwezonyango luphononongo lophando oluvavanya unyango olutsha lwalo i-squamous cell lung cancer. Izigulana zinokuthatha inxaxheba kulingo lwezonyango ukufikelela kunyango oluphambili. I-Shandong Baofa Cancer Research Institute ithatha inxaxheba ngokukhutheleyo kulingo lwezonyango, inika izigulane ukufikelela kuphuculo lwamva nje kunyango lomhlaza. IZiko loPhando ngoMhlaza laseShandong Baofa, sizinikele ekunikeni ukhathalelo olubanzi kunye nolomntu kwizigulana ezine i-squamous cell lung cancer. Iqela lethu leengcali kwiinkalo zonke libandakanya ii-oncologists zonyango, ii-oncologists ngemitha, oogqirha botyando, kunye neengcali ezixhasayo zokhathalelo. Sinikezela ngeendlela zokuxilonga kunye nonyango lwangoku, kubandakanywa utyando, unyango lwemitha, ichemotherapy, unyango olujoliswe kuyo, i-immunotherapy, kunye novavanyo lwezonyango.Siyaqonda ukuba ukuxilongwa komhlaza kunokuba nzima. Yiyo loo nto sizibophelele ekuboneleleni ngovelwano nokhathalelo lwenkxaso kulo lonke uhambo lwakho lomhlaza. Qhagamshelana nathi namhlanje ukufunda banzi ngeenkonzo zethu kunye nendlela esinokukunceda ngayo.Ukuphila noMhlaza weSquamous Cell LungUkuhlala ne i-squamous cell lung cancer zinokuzisa iingxaki ezininzi. Ukulawula iimpawu, ukujamelana nemiphumo emibi yonyango, kunye nokujongana neemfuno zeemvakalelo kunye nezengqondo yonke imiba ebalulekileyo yokunyamekela. Amaqela enkxaso, iingcebiso, kunye neenkonzo zokhathalelo lonyango zinokunceda izigulane kunye neentsapho zabo ukuba zihambe kule mingeni.Izibonelelo kunye neNkxasoImibutho emininzi inikezela ngezibonelelo kunye nenkxaso kubantu abanomhlaza wemiphunga, kuquka: I-American Cancer Society (i-American Cancer Society)www.cancer.org) ISiseko soPhando ngoMhlaza weLung (www.lungcancerresearchfoundation.orgUmbutho wamaLung waseMelika (www.lung.org)IsipheloUmhlaza wemiphunga yeeseli zesquamous sisifo esiyingozi, kodwa ngokufunyaniswa kwangaphambili kunye nonyango olufanelekileyo, izigulane ezininzi zinokufikelela kwiziphumo ezilungileyo. Ukuqonda izinto ezinobungozi, iimpawu, iindlela zokuxilonga, kunye nokhetho lonyango lubalulekile kulawulo olusebenzayo. KwiZiko loPhando ngoMhlaza laseShandong Baofa, sizibophelele ekuboneleleni ngolona khathalelo luphezulu lwezigulana ezine i-squamous cell lung cancer.Ukuziphendulela: Eli nqaku libonelela ngolwazi ngokubanzi kwaye akufanele lithathwe njengengcebiso yezonyango. Soloko udibana nengcali yokhathalelo lwempilo olufanelekileyo ukuze uxilongwe kunye nonyango lweemeko zonyango.IiReferensi: Umbutho womhlaza waseMelika. (n.d.). Yintoni uMhlaza weMiphunga? Ifunyenwe kwi https://www.cancer.org/cancer/lung-cancer/about/what-is-lung-cancer.html Iziko lomhlaza leSizwe. (n.d.). Unyango loMhlaza weMiphunga (PDQ?)–Uguqulelo lwesigulana. Ifunyenwe kwi https://www.cancer.gov/types/lung/patient/non-small-cell-lung-treatment-pdq